STEPdb: Sub-cellular Topologies of E.coli Polypeptides.

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E.coli BL21(DE3) proteome

(mouse over and click on the one letter topology symbols to see which proteins of this specific subproteome are localized in each location)

Bacterial cell cartoon of sub-cellular locations


Protein ID
(Uniprot)
Accession
(Uniprot)
Gene Name
Order Locus Name
Protein Name
(Uniprot)
Full Name
Symbol
Uniprot
First Level
Secretion
System
First Level
Targeting
Chaperoning
Second Level
Secretion
System
Second Level
Targeting
Chaperoning
E.coli Core
Proteome
(yes/no)
basic proteome
C6EBH0_ECOBD
C6EBH0
arcA
B21_04242 ECBD_3619 ECD_04277
DNA-binding response regulator in two-component regulatory system with ArcB or CpxA (Two component transcriptional regulator, winged helix family)
Nucleoid, Peripheral inner membrane protein facing the cytoplasm
N,F1
 
 
 
 
 
yes
yes
C6EBI1_ECOBD
C6EBI1
nadR
B21_04231 ECBD_3630 ECD_04266
Nicotinamide-nucleotide adenylyltransferase (Transcriptional regulator, XRE family)
Nucleoid, Peripheral inner membrane protein facing the cytoplasm
N,F1
 
 
 
 
 
yes
yes
C6EBC2_ECOBD
C6EBC2
 
ECBD_1702
Flagellar hook-length control protein
Cytoplasmic, Extra-cellular
A,X
 
 
 
 
 
 
yes
C6EBM9_ECOBD
C6EBM9
mrr
B21_04183 ECBD_3679 ECD_04217
Methylated adenine and cytosine restriction protein (Restriction endonuclease)
Cytoplasmic
A
 
 
 
 
 
 
yes
C6EBN0_ECOBD
C6EBN0
hsdR
B21_04182 ECBD_3680 ECD_04216
Endonuclease R (EC 3.1.21.3) (Type I site-specific deoxyribonuclease) (EC 3.1.21.3)
Cytoplasmic
A
 
 
 
 
 
 
yes
C6EBN1_ECOBD
C6EBN1
hsdM
B21_04181 ECBD_3681 ECD_04215
DNA methylase M (EC 2.1.1.72) (Site-specific DNA-methyltransferase (Adenine-specific)) (EC 2.1.1.72)
Cytoplasmic
A
 
 
 
 
 
 
yes
C6EBN4_ECOBD
C6EBN4
symE

yjiW

B21_04177 ECBD_3685 ECD_04213
Endoribonuclease symE (EC 3.1.-.-)
Cytoplasmic
A
Cytoplasm
 
 
 
 
 
yes
C6EBN5_ECOBD
C6EBN5
 
ECBD_3686
ATPase associated with various cellular activities AAA_5
Cytoplasmic
A
 
 
 
 
 
 
yes
C6EBN6_ECOBD
C6EBN6
mcrC
B21_04175 ECBD_3687 ECD_04211
5-methylcytosine-specific restriction enzyme McrBC, subunit McrC
Cytoplasmic
A
 
 
 
 
 
 
yes
C6EBN9_ECOBD
C6EBN9
yjiPQ

yjiP

B21_04170 ECBD_3691 ECD_04207
Predicted transposase (Putative transposase YhgA family protein)
Cytoplasmic
A
 
 
 
 
 
 
no
C6EBP0_ECOBD
C6EBP0
 
ECBD_3692
Putative uncharacterized protein
Cytoplasmic
A
 
 
 
 
 
 
yes
C6EKS8_ECOBD
C5W0M7
ybl15
B21_00493 ECBD_3120
Putative uncharacterized protein
Cytoplasmic
A
 
 
 
 
 
 
yes
C6EBP4_ECOBD
C6EBP4
yjiL
B21_04166 ECBD_3696 ECD_04203
CoA-substrate-specific enzyme activase (EC 1.3.99.15) (Predicted ATPase, activator of (R)-hydroxyglutaryl-CoA dehydratase)
Cytoplasmic
A
 
 
 
 
 
 
yes
C6EBP8_ECOBD
C6EBP8
kptA
B21_04163 ECBD_3700 ECD_04200
Phosphotransferase KptA/Tpt1 (RNA 2'-phosphotransferase-like protein) (EC 2.7.-.-)
Cytoplasmic
A
 
 
 
 
 
 
yes
C6EBQ1_ECOBD
C6EBQ1
iadA
B21_04159 ECBD_3703 ECD_04197
Isoaspartyl dipeptidase
Cytoplasmic
A
 
 
 
 
 
 
yes
C6EBQ3_ECOBD
C6EBQ3
yjiD

iraD

B21_04157 ECBD_3705 ECD_04195
DNA replication/recombination/repair protein (GPW/gp25 family protein)
Cytoplasmic
A
 
 
 
 
 
 
yes
C6EBQ4_ECOBD
C6EBQ4
 
ECBD_3706
Putative uncharacterized protein
Cytoplasmic
A
 
 
 
 
 
 
yes
C6EBQ5_ECOBD
C6EBQ5
 
ECBD_3707
Putative uncharacterized protein
Cytoplasmic
A
 
 
 
 
 
 
yes
C6EBQ7_ECOBD
C6EBQ7
yjiC
B21_04156 ECBD_3709 ECD_04194
Putative uncharacterized protein (Putative uncharacterized protein yjiC)
Cytoplasmic
A
 
 
 
 
 
 
yes
C6EBQ9_ECOBD
C6EBQ9
 
ECBD_3711
Putative uncharacterized protein
Cytoplasmic
A
 
 
 
 
 
 
yes
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