stepidecocyc_idecocyc_namesublocisubunit_entrysubunit_accecocyc_subunit
step2128N/A glutamic acid–dependent acid resistance system(GDAR)A,F1DCEA_ECOLI
DCEB_ECOLI
P69910
P69908
[GadA]6[GadB]6
step1605CPLX0-78821,4-dihydroxy-2-naphthoyl-CoA synthaseCytoplasmic (A)MENB_ECOLIP0ABU0[MenB]6
step1700DXPREDISOM-CPLX1-deoxy-D-xylulose 5-phosphate reductoisomeraseCytoplasmic (A)DXR_ECOLIP45568[Dxr]2
step1432CPLX0-7431-deoxyxylulose-5-phosphate synthaseCytoplasmic (A)DXS_ECOLIP77488[Dxs]2
step1452CPLX0-75641-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductaseCytoplasmic (A)ISPH_ECOLIP62623[IspH]2
step10251-PFK1-phosphofructokinaseCytoplasmic (A)K1PF_ECOLIP0AEW9[FruK]2
step1537CPLX0-772716S rRNA m3U1498 methyltransferaseCytoplasmic (A)RSME_ECOLIP0AGL7[RsmE]2
step2019CPLX0-797716S rRNA m4C1402 methyltransferaseF1*RSMH_ECOLIP60390[RsmH]2
step1878PHOSGLYCMUTASE2,3-bisphosphoglycerate-dependent phosphoglyceratemutaseCytoplasmic (A)GPMA_ECOLIP62707[GpmA]2
step1231CPLX0-14012,3-diaminopropionate ammonia-lyaseCytoplasmic (A)DPAL_ECOLIP66899[YgeX]2
step1709ENTA-CPLX2,3-dihydro-2,3-dihydroxybenzoate dehydrogenaseCytoplasmic (A)ENTA_ECOLIP15047[EntA]8
step1710ENTE-CPLX2,3-dihydroxybenzoate-AMP ligase / Ap4A synthetasePeripheral inner membrane protein facing the cytoplasm (F1)ENTE_ECOLIP10378[EntE]2
step1684DHPDIOXYGEN-CPLX2,3-dihydroxyphenylpropionate 1,2-dioxygenaseCytoplasmic (A)MHPB_ECOLIP0ABR9[MhpB]4
step1265CPLX0-20612,3-diketo-L-gulonate reductaseNucleoid (N)YIAJ_ECOLIP37671[YiaJ]2
step1115AKBLIG-CPLX2-amino-3-ketobutyrate CoA ligaseCytoplasmic (A)KBL_ECOLIP0AB77[Kbl]2
step1136AROF-CPLX2-dehydro-3-deoxyphosphoheptonate aldolaseCytoplasmic (A)AROF_ECOLIP00888[AroF]2
step1137AROG-CPLX2-dehydro-3-deoxyphosphoheptonate aldolaseCytoplasmic (A)AROG_ECOLIP0AB91[AroG]4
step1138AROH-CPLX2-dehydro-3-deoxyphosphoheptonate aldolaseCytoplasmic (A)AROH_ECOLIP00887[AroH]2
step1640CPLX0-79502-hydroxy-6-oxononatrienedioate hydrolaseCytoplasmic (A)MHPC_ECOLIP77044[MhpC]2
step1641CPLX0-79512-hydroxypentadienoate hydrataseCytoplasmic (A)MHPD_ECOLIP77608[MhpD]5
step1533CPLX0-77232-keto-3-deoxy-L-rhamnonate aldolaseCytoplasmic (A)RHMA_ECOLIP76469[RhmA]6
step1214CPLX0-10212-methylisocitrate lyaseIntegral Inner Membrane (B)PRPB_ECOLIP77541[PrpB]4
step1190CPLX-1632-O-α-mannosyl-D-glycerate transporting phosphotransferase systemIntegral Inner Membrane (B)HRSA_ECOLIP54745[HrsA]2
step1701E1O2-oxoglutarate decarboxylase, thiamine-requiringCytoplasmic (A)ODO1_ECOLIP0AFG3[Odo1]12
step10262OXOGLUTARATEDEH-CPLX2-oxoglutarate dehydrogenase complexPeripheral inner membrane protein facing the cytoplasm (F1)DLDH_ECOLI
ODO2_ECOLI
ODO1_ECOLI
P0A9P0
P0AFG6
P0AFG3
[(Odo1)12][(Odo2)24][(DldH)2]
step1442CPLX0-75252-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthaseCytoplasmic (A)MEND_ECOLIP17109[MenD]2
step1217CPLX0-112123S rRNA 2'-O-ribose G2251 methyltransferaseCytoplasmic (A)RLMB_ECOLIP63177[RlmB]2
step1429CPLX0-742323S rRNA m3Ψ1915 methyltransferaseCytoplasmic (A)RLMH_ECOLIP0A8I8[RlmH]2
step1536CPLX0-772623S rRNA m5C1962 methyltransferaseCytoplasmic (A)RLMI_ECOLIP75876[RlmI]2
step1422CPLX0-7212C-methyl-D-erythritol 2,4-cyclodiphosphate synthaseCytoplasmic (A)ISPF_ECOLIP62617[IspF]3
step1500CPLX0-76752Fe-2S cluster-containing proteinCytoplasmic (A)YEAW_ECOLIP0ABR7[YeaW]3
step1855PAPSSULFOTRANS-CPLX3'-phospho-adenylylsulfate reductaseCytoplasmic (A)CYSH_ECOLIP17854[CysH]2
step1693DIOHBUTANONEPSYN-CPLX3,4-dihydroxy-2-butanone 4-phosphate synthasePeripheral inner membrane protein facing the cytoplasm (F1)RIBB_ECOLIP0A7J0[RibB]2
step1135AROD-CPLX3-dehydroquinate dehydrataseCytoplasmic (A)AROD_ECOLIP05194[AroD]2
step1799KDO-8PPHOSPHAT-CPLX3-deoxy-D-manno-octulosonate 8-phosphate phosphatasePeripheral inner membrane protein facing the cytoplasm (F1)KDSC_ECOLIP0ABZ4[KdsC]4
step1800KDO-8PSYNTH-CPLX3-deoxy-D-manno-octulosonate 8-phosphate synthaseCytoplasmic (A)KDSA_ECOLIP0A715[KdsA]4
step1260CPLX0-19623-hydroxy acid dehydrogenaseCytoplasmic (A)YDFG_ECOLIP39831[YdfG]4
step1720FABZ-CPLX3-hydroxy-acyl-[acyl-carrier-protein] dehydratasePeripheral inner membrane protein facing the cytoplasm (F1)FABZ_ECOLIP0A6Q6[FabZ]
step1718FABA-CPLX3-hydroxydecanoyl-[acp] dehydraseCytoplasmic (A)FABA_ECOLIP0A6Q3[FabA]2
step10273-ISOPROPYLMALDEHYDROG-CPLX3-isopropylmalate dehydrogenaseCytoplasmic (A)LEU3_ECOLIP30125[LeuB]2
step1545CPLX0-77443-keto-L-gulonate 6-phosphate decarboxylaseCytoplasmic (A)ULAD_ECOLIP39304[UlaD]2
step10293-METHYL-2-OXOBUT-OHCH3XFER-CPLX3-methyl-2-oxobutanoate hydroxymethyltransferase Cytoplasmic (A)PANB_ECOLIP31057[PanB]10
step1326CPLX0-3013-octaprenyl-4-hydroxybenzoate carboxy-lyasePeripheral inner membrane protein facing the cytoplasm (F1)UBID_ECOLIP0AAB4[UbiD]6
step2018CPLX0-80053-oxoacyl-[acyl-carrier-protein] reductasePeripheral inner membrane protein facing the cytoplasm (F1)FABG_ECOLIP0AEK2[FabG]4
step1783HCAMULTI-CPLX3-phenylpropionate dioxygenase systemCytoplasmic (A)HCAE_ECOLI
HCAD_ECOLI
HCAF_ECOLI
HCAC_ECOLI
P0ABR5
P77650
Q47140
P0ABW0
[HcaC][HcaD][HcaF][HcaE]
step1753GLUCOSE-1-PHOSPHAT-CPLX3-phytase / glucose-1-phosphatasePeriplasmic (G)AGP_ECOLIP19926[Agp]2
step1403CPLX0-395330S ribosomal subunit Ribosomal (r)RS1_ECOLI
RS2_ECOLI
RS3_ECOLI
RS4_ECOLI
RS5_ECOLI
RS6_ECOLI
RS7_ECOLI
RS8_ECOLI
RS9_ECOLI
RS10_ECOLI
RS11_ECOLI
RS12_ECOLI
RS13_ECOLI
RS14_ECOLI
RS15_ECOLI
RS16_ECOLI
RS17_ECOLI
RS18_ECOLI
RS19_ECOLI
RS20_ECOLI
RS21_ECOLI
SRA_ECOLI
P0AG67
P0A7V0
P0A7V3
P0A7V8
P0A7W1
P02358
P02359
P0A7W7
P0A7X3
P0A7R5
P0A7R9
P0A7S3
P0A7S9
P0AG59
P0ADZ4
P0A7T3
P0AG63
P0A7T7
P0A7U3
P0A7U7
P68679
P68191
[RrsA][RpsA][RpsB][RpsC][RpsD][RpsE][RpsF][RpsG][RpsH][RpsI][RpsJ][RpsK][RpsL][RpsM][RpsN][RpsO][RpsP][RpsQ][RpsR][RpsS][RpsT][RpsU][Sra]
step1740GABATRANSAM-CPLX4-aminobutyrate transaminaseCytoplasmic (A)GABT_ECOLIP22256[GabT]2
step1376CPLX0-38414-diphosphocytidyl-2-C-methylerythritol kinaseCytoplasmic (A)ISPE_ECOLIP62615[IspE]2
step1282CPLX0-2344-diphosphocytidyl-2C-methyl-D-erythritol synthaseCytoplasmic (A)ISPD_ECOLIQ46893[IspD]2
step1596CPLX0-78474-hydroxy-L-threonine phosphate dehydrogenase, NAD-dependentCytoplasmic (A)PDXA_ECOLIP19624[PdxA]2
step1236CPLX0-15415'-methylthioadenosine/S-adenosylhomocysteinenucleosidaseCytoplasmic (A)MTNN_ECOLIP0AF12[MtnN]2
step1822METHYLENETHFREDUCT-CPLX5,10-methylenetetrahydrofolate reductaseCytoplasmic (A)METF_ECOLIP0AEZ1[MetF]4
step1631CPLX0-79365-phospho-α-D-ribosyl 1,2-cyclic phosphate phosphodiesterasePeriplasmic (G)PHNP_ECOLIP16692[PhnP]2
step1406CPLX0-395650S ribosomal protein complex L8Ribosomal (r)RL7_ECOLI
RL10_ECOLI
P0A7K2
P0A7J3
[RplJ][(RplL)2]2
step1411CPLX0-396250S ribosomal subunit Ribosomal (r)RRF_ECOLI
RL1_ECOLI
RL2_ECOLI
RL3_ECOLI
RL4_ECOLI
RL5_ECOLI
RL6_ECOLI
RL9_ECOLI
RL10_ECOLI
RL11_ECOLI
RL7_ECOLI
RL13_ECOLI
RL14_ECOLI
RL15_ECOLI
RL16_ECOLI
RL17_ECOLI
RL18_ECOLI
RL19_ECOLI
RL20_ECOLI
RL21_ECOLI
RL22_ECOLI
RL23_ECOLI
RL24_ECOLI
RL25_ECOLI
RL27_ECOLI
P0A805
P0A7L0
P60422
P60438
P60723
P62399
P0AG55
P0A7R1
P0A7J3
P0A7J7
P0A7K2
P0AA10
P0ADY3
P02413
P0ADY7
P0AG44
P0C018
P0A7K6
P0A7L3
P0AG48
P61175
P0ADZ0
P60624
P68919
P0A7L8
[RrlA][RrfA][RplA][RplB][RplC][RplD][RplE][RplF][(RplJ)([RplL]2)2][RplI][RplJ][RplK][RplM][RplN][RplO][RplP][RplQ][RplR][RplS][RplT][RplU][RplV][RplW][RplX][RplY][RpmA]
step1405CPLX0-395550S ribosomal subunit protein L7/L12 dimerRibosomal (r)RL7_ECOLIP0A7K2[RplL]2
step1808LUMAZINESYN-CPLX6,7-dimethyl-8-ribityllumazine synthaseCytoplasmic (A)RISB_ECOLIP61714[RibH]60
step10316PFK-1-CPX6-phosphofructokinase ICytoplasmic (A)K6PF1_ECOLIP0A796[PfkA]4
step10326PFK-2-CPX6-phosphofructokinase IICytoplasmic (A)K6PF2_ECOLIP06999[PfkB]2
step10336PGLUCONDEHYDROG-CPLX6-phosphogluconate dehydrogenase (decarboxylating)Cytoplasmic (A)6PGD_ECOLIP00350[Gnd]2
step1676DAPASYN-CPLX7,8-diaminopelargonic acid synthaseCytoplasmic (A)BIOA_ECOLIP12995[BioA]2
step1357CPLX0-35017-cyano-7-deazaguanine reductaseCytoplasmic (A)QUEF_ECOLIQ46920[QueF]2
step10347-ALPHA-HYDROXYSTEROID-DEH-CPLX7-α-hydroxysteroid dehydrogenaseCytoplasmic (A)HDHA_ECOLIP0AET8[HdhA]4
step10357KAPSYN-CPLX8-amino-7-oxononanoate synthaseCytoplasmic (A)BIOF_ECOLIP12998[BioF]2
step1356CPLX0-3482acetaldehyde dehydrogenaseCytoplasmic (A)ALDB_ECOLIP37685[AldB]4
step1644CPLX0-7955acetate / glycolate transporterIntegral Inner Membrane (B)ACTP_ECOLIP32705[ActP]2
step1091ACETOACETYL-COA-TRANSFER-CPLXacetoacetyl-CoA transferaseCytoplasmic (A)ATOA_ECOLI
ATOD_ECOLI
P76459
P76458
[(AtoA)2][(AtoD)2]
step1478CPLX0-7643acetohydroxy acid isomeroreductaseCytoplasmic (A)ILVC_ECOLIP05793[IlvC]4
step1092ACETOLACTSYNI-CPLXacetohydroxybutanoate synthase / acetolactate synthaseCytoplasmic (A)ILVN_ECOLI
ILVB_ECOLI
P0ADF8
P08142
[IlvB]2[IlvN]2
step1093ACETOLACTSYNII-CPLXacetohydroxybutanoate synthase / acetolactate synthaseCytoplasmic (A)ILVM_ECOLIP0ADG1[IlvG_1][IlvG_2][IlvM]
step1903PYRUVOXID-CPLXacetoin synthesis / pyruvate oxidasePeripheral inner membrane protein facing the cytoplasm (F1)POXB_ECOLIP07003[PoxB]4
step1094ACETOLACTSYNIII-CPLXacetolactate synthase / acetohydroxybutanoate synthaseCytoplasmic (A)ILVH_ECOLI
ILVI_ECOLI
P00894
P00893
[IlvI]2[IlvH]2
step2020CPLX0-8033acetyl esteraseCytoplasmic (A)AES_ECOLIP23872[Aes]2
step1095ACETYL-COA-ACETYLTRANSFER-CPLXacetyl-CoA acetyltransferaseCytoplasmic (A)ATOB_ECOLIP76461[AtoB]4
step1096ACETYL-COA-CARBOXYLMULTI-CPLXacetyl-CoA carboxylaseCytoplasmic (A)ACCD_ECOLI
ACCA_ECOLI
ACCC_ECOLI
BCCP_ECOLI
P0A9Q5
P0ABD5
P24182
P0ABD8
[(AccA)2(AccD)2][(AccC)2][(AccB)2]
step1097ACETYL-COA-CARBOXYLTRANSFER-CPLXacetyl-CoA carboxyltransferaseCytoplasmic (A)ACCD_ECOLI
ACCA_ECOLI
P0A9Q5
P0ABD5
[AccA]2[AccD]2
step1152ATOA-CPLXacetyl-CoA:acetoacetyl-CoA transferase, β subunitCytoplasmic (A)ATOA_ECOLIP76459[AtoA]2
step1153ATOD-CPLXacetyl-CoA:acetoacetyl-CoA transferase, β subunitCytoplasmic (A)ATOD_ECOLIP76458[AtoD]2
step2021CPLX0-8032acetyl-CoA:oxalate CoA-transferaseCytoplasmic (A)YFDE_ECOLIP76518[YfdE]2
step1098ACETYLGLUTKIN-CPLXacetylglutamate kinaseCytoplasmic (A)ARGB_ECOLIP0A6C8[ArgB]2
step1099ACETYLORNDEACET-CPLXacetylornithine deacetylaseCytoplasmic (A)ARGE_ECOLIP23908[ArgE]2
step1206CPLX-722acid phosphatasePeriplasmic (G)PPA_ECOLIP07102[AppA]2
step1126APHA-CPLXacid phosphatase/phosphotransferasePeriplasmic (G)APHA_ECOLIP0AE22[AphA]4
step1555CPLX0-7760aconitate hydratase 1Cytoplasmic (A)ACON1_ECOLIP25516[AcnA]2
step1962TRANS-CPLX-201AcrAB-TolC multidrug efflux transport systemProtein complex spanning both membranesTOLC_ECOLI
ACRB_ECOLI
ACRA_ECOLI
P02930
P31224
P0AE06
[AcrA][(TolC)3][AcrB]3
step1389CPLX0-3932AcrAD-TolC multidrug efflux transport systemProtein complex spanning both membranesTOLC_ECOLI
ACRD_ECOLI
ACRA_ECOLI
P02930
P24177
P0AE06
[AcrD][AcrA][(TolC)3]
step2011N/AAcrB homotrimerIntegral Inner Membrane (B)ACRB_ECOLIP31224[AcrB]3
step1268CPLX0-2141AcrEF-TolC multidrug efflux transport systemProtein complex spanning both membranesTOLC_ECOLI
ACRE_ECOLI
ACRF_ECOLI
P02930
P24180
P24181
[AcrE][AcrF][(TolC)3]
step2136N/AActive core of bacterial cellulose synthaseIntegral Inner Membrane (B)BCSB_ECOLI
BCSA_ECOLI
P37653
P37652
[BcsA][BcsB]
step1107ADENPRIBOSYLTRAN-CPLXadenine phosphoribosyltransferaseCytoplasmic (A)APT_ECOLIP69503[Apt]2
step1924SAMDECARB-CPLXadenosylmethionine decarboxylaseCytoplasmic (A)SPED_ECOLIP0A7F6[SpeD]4[SpeD]4
step1648CPLX0-7959adenylosuccinate lyaseCytoplasmic (A)PUR8_ECOLIP0AB89[PurB]4
step1108ADENYLOSUCCINATE-SYN-DIMERadenylosuccinate synthetaseCytoplasmic (A)PURA_ECOLIP0A7D4[PurA]2
step1109ADENYLYLSULFKIN-CPLXadenylylsulfate kinaseCytoplasmic (A)CYSC_ECOLIP0A6J1[CysC]2
step1448CPLX0-7535AdiC arginine:agmatine antiporterIntegral Inner Membrane (B)ADIC_ECOLIP60061[AdiC]2
step1367CPLX0-3681ADP-L-glycero-D-mannoheptose-6-epimeraseCytoplasmic (A)HLDD_ECOLIP67910[HldD]5
step1368CPLX0-3721ADP-sugar pyrophosphataseCytoplasmic (A)ADPP_ECOLIQ93K97[NudF]2
step1223CPLX0-1221ADP-sugar pyrophosphorylaseCytoplasmic (A)NUDE_ECOLIP45799[NudE]2
step1723FAO-CPLXaerobic fatty acid oxidation complexCytoplasmic (A)FADB_ECOLI
FADA_ECOLI
P21177
P21151
[(FadB)2][(FadA)2]
step1113AGMATIN-CPLXagmatinaseCytoplasmic (A)SPEB_ECOLIP60651[SpeB]2
step1439CPLX0-7465alanine racemase 2, PLP-bindingCytoplasmic (A)ALR2_ECOLIP29012[DadX]2
step1116ALAS-CPLXalanyl-tRNA synthetase and DNA-binding transcriptional repressorN,F1SYA_ECOLIP00957[AlaS]2
step1572CPLX0-7805aldehyde dehydrogenasePeriplasmic (G)YAGR_ECOLI
YAGS_ECOLI
YAGT_ECOLI
P77489
P77324
P77165
[YagT][YagS][YagR]
step1117ALD-CPLXaldehyde dehydrogenase A, NAD-linkedCytoplasmic (A)ALDA_ECOLIP25553[AldA]4
step1077ABC-56-CPLXaliphatic sulfonate ABC transporterIntegral Inner Membrane (B)SSUA_ECOLI
SSUC_ECOLI
SSUB_ECOLI
P75853
P75851
P0AAI1
[SsuA][SsuC]2[SsuB]2
step1118ALKAPHOSPHA-CPLXalkaline phosphatasePeriplasmic (G)PPB_ECOLIP00634[PhoA]2
step1276CPLX0-225alkanesulfonate monooxygenase, FMNH2-dependentCytoplasmic (A)SSUD_ECOLIP80645[SsuD]4
step1299CPLX0-245alkylhydroperoxide reductaseCytoplasmic (A)AHPC_ECOLI
AHPF_ECOLI
P0AE08
P35340
[AhpC]2[AhpF]2
step1207CPLX-7524allantoate amidohydrolaseCytoplasmic (A)ALLC_ECOLIP77425[AllC]2
step1204CPLX-64allantoinaseCytoplasmic (A)ALLB_ECOLIP77671[AllB]4
step1910RIB5PISOMB-CPLXallose-6-phosphate isomerase / ribose-5-phosphateisomerase BCytoplasmic (A)RPIB_ECOLIP37351[RpiB]2
step1894PRPPAMIDOTRANS-CPLXamidophosphoribosyl transferaseCytoplasmic (A)PUR1_ECOLIP0AG16[PurF]4
step1106ADCLY-CPLXaminodeoxychorismate lyaseCytoplasmic (A)PABC_ECOLIP28305[PabC]2
step1851PABASYN-CPLXaminodeoxychorismate synthaseCytoplasmic (A)PABB_ECOLI
PABA_ECOLI
P05041
P00903
[PabB][PabA]
step1330CPLX0-3061aminopeptidase A/I and DNA-binding transcriptional repressorCytoplasmic (A)AMPA_ECOLIP68767[PepA]6
step1445CPLX0-7532ammonia / ammonium transporterIntegral Inner Membrane (B)AMTB_ECOLIP69681[AmtB]3
step1121AMP-NUCLEOSID-CPLXAMP nucleosidaseCytoplasmic (A)AMN_ECOLIP0AE12[Amn]6
step1244CPLX0-1668anaerobic fatty acid oxidation complexCytoplasmic (A)FADJ_ECOLI
FADI_ECOLI
P77399
P76503
[(FadJ)2][(FadI)2]
step1839NRDACTMULTI-CPLXanaerobic nucleoside-triphosphate reductase activatingsystemCytoplasmic (A)NRDD_ECOLI
FENR_ECOLI
NRDG_ECOLI
P28903
P28861
P0A9N8
[(NrdD)2][(NrdG)2][Fpr]
step1125ANTHRANSYN-CPLXanthranilate synthasePeripheral inner membrane protein facing the cytoplasm (F1)TRPE_ECOLI
TRPG_ECOLI
P00895
P00904
[TrpE]2[TrpD]2
step1483CPLX0-7648anti-sigma factorPeriplasmic (G)RSEB_ECOLIP0AFX9[RseB]2
step1811LYSU-CPLXAp3A synthetase / Ap4A synthetase / lysyl-tRNAsynthetaseCytoplasmic (A)SYK2_ECOLIP0A8N5[LysU]2
step1127APO-ENTBapo-EntB multimerPeripheral inner membrane protein facing the cytoplasm (F1)ENTB_ECOLIP0ADI4[EntB]5
step1486CPLX0-7653AqpZ water MIP channelIntegral Inner Membrane (B)AQPZ_ECOLIP60844[AqpZ]4
step1045ABC-2-CPLXarabinose ABC transporterIntegral Inner Membrane (B)ARAG_ECOLI
ARAH_ECOLI
ARAF_ECOLI
P0AAF3
P0AE26
P02924
[AraG]2[AraH]2[AraF]
step1856PC00003AraC DNA-binding transcriptional dual regulatorNucleoid (N)ARAC_ECOLIP0A9E0[AraC]2
step1131ARCB-CPLXArcB sensory histidine kinaseIntegral Inner Membrane (B)ARCB_ECOLIP0AEC3[ArcB]2
step1063ABC-4-CPLXarginine ABC transporterIntegral Inner Membrane (B)ARTI_ECOLI
ARTJ_ECOLI
ARTQ_ECOLI
ARTP_ECOLI
ARTM_ECOLI
P30859
P30860
P0AE34
P0AAF6
P0AE30
[ArtP]2[ArtM][ArtQ][ArtI][ArtJ]
step1132ARGDECARBOXBIO-CPLXarginine decarboxylase, biosyntheticCytoplasmic (A)SPEA_ECOLIP21170[SpeA]4
step1133ARGDECARBOXDEG-CPLXarginine decarboxylase, degradativeCytoplasmic (A)ADIA_ECOLIP28629[AdiA]10
step2126N/Aarginine-dependent acid resistance system (ADAR)Integral Inner Membrane (B)ADIA_ECOLI
ADIC_ECOLI
P28629
P60061
[AdiC]2[AdiA]10
step1287CPLX0-238argininosuccinate synthaseCytoplasmic (A)ASSY_ECOLIP0A6E4[ArgG]4
step1497CPLX0-7669ArgP DNA-binding transcriptional activatorNucleoid (N)ICIA_ECOLIP0A8S1[IciA]2
step1858PC00005ArgR transcriptional dual regulatorNucleoid (N)ARGR_ECOLIP0A6D0[ArgR]6
step1530CPLX0-7720ArnE/ArnF undecaprenyl-phosphate-α-L-Ara4N flippaseIntegral Inner Membrane (B)ARNF_ECOLI
ARNE_ECOLI
P76474
Q47377
[ArnE][ArnF]
step1205CPLX-7arsenite:H+ antiporterIntegral Inner Membrane (B)ARSB_ECOLIP0AB93[ArsB]2
step1542CPLX0-7734ArsR DNA-binding transcriptional repressorNucleoid (N)ARSR_ECOLIP37309[ArsR]2
step1541CPLX0-7733AsnC DNA-binding transcriptional dual regulatorNucleoid (N)ASNC_ECOLIP0ACI6[AsnC]2
step1123ANSA-CPLXasparaginase ICytoplasmic (A)ASPG1_ECOLIP0A962[AspG1]4
step1124ANSB-CPLXasparaginase IIPeriplasmic (G)ASPG2_ECOLIP00805[AspG2]4
step1140ASNSYNA-CPLXasparagine synthetase ACytoplasmic (A)ASNA_ECOLIP00963[AsnA]2
step1141ASNSYNB-CPLXasparagine synthetase BCytoplasmic (A)ASNB_ECOLIP22106[AsnB]2
step1139ASNS-CPLXasparaginyl-tRNA synthetaseCytoplasmic (A)SYN_ECOLIP0A8M0[AsnS]2
step1320CPLX0-2901aspartate 1-decarboxylaseCytoplasmic (A)PAND_ECOLIP0A790[PanD]4[PanD]4
step1143ASPAMINOTRANS-DIMERaspartate aminotransferase, PLP-dependentCytoplasmic (A)AAT_ECOLIP00509[Aat]2
step1144ASPARTASE-CPLXaspartate ammonia-lyaseCytoplasmic (A)ASPA_ECOLIP0AC38[AspA]4
step1145ASPCARBCAT-TRIMERaspartate carbamoyltransferase, catalytic subunitCytoplasmic (A)PYRB_ECOLIP0A786[PyrB]3
step1146ASPCARBREG-DIMERaspartate carbamoyltransferase, regulatory subunitCytoplasmic (A)PYRI_ECOLIP0A7F3[PyrI]2
step1148ASPKINIHOMOSERDEHYDROGI-CPLXaspartate kinase / homoserine dehydrogenaseCytoplasmic (A)AK1H_ECOLIP00561[Ak1H]4
step1149ASPKINIIHOMOSERDEHYDROGII-CPLXaspartate kinase / homoserine dehydrogenaseCytoplasmic (A)AK2H_ECOLIP00562[Ak2H]2
step1150ASPKINIII-CPLXaspartate kinase IIICytoplasmic (A)AK3_ECOLIP08660[Ak3]2
step1142ASP-SEMIALDEHYDE-DEHYDROGENASE-CPLXaspartate semialdehyde dehydrogenaseIntegral Inner Membrane (B)DHAS_ECOLIP0A9Q9[Asd]2
step1147ASPCARBTRANS-CPLXaspartate transcarbamylaseCytoplasmic (A)PYRB_ECOLI
PYRI_ECOLI
P0A786
P0A7F3
[(PyrB)3]2[(PyrI)2]3
step1151ASPS-CPLXaspartyl-tRNA synthetasePeripheral inner membrane protein facing the cytoplasm (F1)SYD_ECOLIP21889[Syd]2
step1601CPLX0-7870AtoS sensory histidine kinaseIntegral Inner Membrane (B)ATOS_ECOLIQ06067[AtoS]2
step1623CPLX0-7923ATP independent periplasmic chaperonePeriplasmic (G)SPY_ECOLIP77754[Spy]2
step1459CPLX0-7614ATP phosphoribosyltransferaseCytoplasmic (A)HIS1_ECOLIP60757[HisG]2
step1159ATPSYN-CPLXATP synthaseIntegral Inner Membrane (B)ATPB_ECOLI
ATPL_ECOLI
ATPD_ECOLI
ATP6_ECOLI
ATPE_ECOLI
ATPA_ECOLI
ATPF_ECOLI
ATPG_ECOLI
P0ABB4
P68699
P0ABA4
P0AB98
P0A6E6
P0ABB0
P0ABA0
P0ABA6
[([AtpL]10)([AtpF]2)[Atp6]][(AtpE)(AtpD)([AtpA]3)(AtpG)([AtpB]3)]
step1716F-O-CPLXATP synthase F0 complexIntegral Inner Membrane (B)ATPL_ECOLI
ATP6_ECOLI
ATPF_ECOLI
P68699
P0AB98
P0ABA0
[(AtpL)10][(AtpF)2][Atp6]
step1158ATPF-CPLXATP synthase F0 complex - b subunitIntegral Inner Membrane (B)ATPF_ECOLIP0ABA0[AtpF]2
step1157ATPE-CPLXATP synthase F0 complex - subunit cIntegral Inner Membrane (B)ATPL_ECOLIP68699[AtpL]10
step1715F-1-CPLXATP synthase F1 complexPeripheral inner membrane protein facing the cytoplasm (F1)ATPB_ECOLI
ATPD_ECOLI
ATPE_ECOLI
ATPA_ECOLI
ATPG_ECOLI
P0ABB4
P0ABA4
P0A6E6
P0ABB0
P0ABA6
[AtpE][AtpD][(AtpA)3][AtpG][[AtpB]3]
step1154ATPA-CPLXATP synthase F1 complex - alpha subunitPeripheral inner membrane protein facing the cytoplasm (F1)ATPA_ECOLIP0ABB0[AtpA]3
step1156ATPD-CPLXATP synthase F1 complex - beta subunitPeripheral inner membrane protein facing the cytoplasm (F1)ATPB_ECOLIP0ABB4[AtpB]3
step1079ABC-58-CPLXautoinducer-2 ABC transporterIntegral Inner Membrane (B)LSRA_ECOLI
LSRD_ECOLI
LSRB_ECOLI
LSRC_ECOLI
P77257
P0AFS1
P76142
P77672
[LsrB][LsrD][LsrC][LsrA]2
step1232CPLX0-1421bacterioferritinCytoplasmic (A)BFR_ECOLIP0ABD3[Bfr]24
step2017N/Abd oxidase and YhcB subcomplexIntegral Inner Membrane (B)CYDA_ECOLI
CYDB_ECOLI
YHCB_ECOLI
P0ABJ9
P0ABK2
P0ADW3
[CydA][CydB][YhcB]
step1162BADH-CPLXbetaine aldehyde dehydrogenaseCytoplasmic (A)BETB_ECOLIP17445[BetB]4
step1318CPLX0-2861BglG transcriptional antiterminatorPeripheral inner membrane protein facing the cytoplasm (F1)BGLG_ECOLIP11989[BglG]2
step2022CPLX0-7657BglG-phosphatePeripheral inner membrane protein facing the cytoplasm (F1)BGLG_ECOLIP11989[BglG]2
step2023CPLX0-8092bifunctional β-cystathionase, PLP-dependent and regulator of maltose regulonCytoplasmic (A)MALY_ECOLIP23256[MalY]2
step1683DHHB-METHYLTRANSFER-CPLXbifunctional 3-demethylubiquinone-8 3-O-methyltransferase and 2-octaprenyl-6-hydroxyphenol methylaseCytoplasmic (A)UBIG_ECOLIP17993[UbiG]2
step1726FOLD-CPLXbifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolaseCytoplasmic (A)FOLD_ECOLIP24186[FolD]2
step1556CPLX0-7761bifunctional aconitate hydratase 2 and 2-methylisocitrate dehydrataseCytoplasmic (A)ACON2_ECOLIP36683[AcnB]2
step1669CYSSYNMULTI-CPLXbifunctional CysEK cysteine biosynthesis complexCytoplasmic (A)CYSK_ECOLI
CYSE_ECOLI
P0ABK5
P0A9D4
[(CysE)6][(CysK)2]
step2151Biochemical studies demonstrated that CpxP maintains a dimeric state but may undergo a slight structural adjustment in response to the inducing cue, alkaline pH.Periplasmic (G)CPXP_ECOLIP0AE85[CpxP]2
step2115N/ABiogenesis of OmpAH,F3SKP_ECOLI
OMPA_ECOLI
P0AEU7
P0A910
[Skp]3[OmpA]
step2114N/ABiogenesis of OmpXH,F3SKP_ECOLI
OMPX_ECOLI
P0AEU7
P0A917
[Skp]3[OmpX]
step1163BCCP-CPLXbiotin carboxyl carrier protein (dimer)Cytoplasmic (A)BCCP_ECOLIP0ABD8[AccB]2
step1165BIOTIN-CARBOXYL-CPLXbiotin carboxylaseCytoplasmic (A)ACCC_ECOLIP24182[AccC]2
step1166BIOTIN-SYN-CPLXbiotin synthaseCytoplasmic (A)BIOB_ECOLIP12996[BioB]2
step1041ABC-15-CPLXbranched chain amino acid ABC transporterIntegral Inner Membrane (B)LIVJ_ECOLI
LIVM_ECOLI
LIVG_ECOLI
LIVH_ECOLI
LIVF_ECOLI
P0AD96
P22729
P0A9S7
P0AEX7
P22731
[LivF][LivG][LivH][LivM][LivJ]
step1167BRANCHED-CHAINAMINOTRANSFER-CPLXbranched-chain amino-acid aminotransferaseCytoplasmic (A)ILVE_ECOLIP0AB80[IlvE]6
step1240CPLX0-1622c-di-GMP phosphodiesterase, heme-regulatedCytoplasmic (A)DCUP_ECOLI
DOSP_ECOLI
P29680
P76129
[DosP]2
step2123N/ACadaverine inhibition /cell survival at acidic pH.Outer Membrane b-barrel (H)OMPF_ECOLI
OMPC_ECOLI
P02931
P06996
[OmpC]3[OmpF]3
step1494CPLX0-7666CaiF transcriptional activatorNucleoid (N)CAIF_ECOLIP0AE58[CaiF]2
step1443CPLX0-7529capsular polysaccharide export apparatusB&IWZA_ECOLI
WZC_ECOLI
P0A930
P76387
[Wza]8[Wzc]4
step1169CARBPSYN-CPLXcarbamoyl phosphate synthetaseCytoplasmic (A)CARB_ECOLI
CARA_ECOLI
P00968
P0A6F1
[CarB]2[CarA]2
step1168CARBODEHYDRAT-CPLXcarbonic anhydrase 1Cytoplasmic (A)CYNT_ECOLIP0ABE9[CynT]2
step1441CPLX0-7521carbonic anhydrase 2Cytoplasmic (A)CAN_ECOLIP61517[Can]4
step2024CPLX0-8010carboxy-S-adenosyl-L-methionine synthaseCytoplasmic (A)CMOA_ECOLIP76290[CmoA]2
step1587CPLX0-7827carboxylate-amine ligaseCytoplasmic (A)CAAL_ECOLIP77213[YbdK]2
step1952THREDEHYDCAT-CPLXcatabolic threonine dehydrataseCytoplasmic (A)TDCB_ECOLIP0AGF6[TdcB]4
step1418CPLX0-646catalytic subcomplex of succinate dehydrogenasePeripheral inner membrane protein facing the cytoplasm (F1)DHSB_ECOLI
DHSA_ECOLI
P07014
P0AC41
[SdhA][SdhB]
step1061ABC-35-CPLXCcmABCDE protoheme IX ABC transporterIntegral Inner Membrane (B)CCMA_ECOLI
CCME_ECOLI
CCMD_ECOLI
CCMC_ECOLI
CCMB_ECOLI
P33931
P69490
P0ABM5
P0ABM1
P0ABL8
[(CcmD)(CcmE)(CcmC)][CcmB][CcmA]2
step1489CPLX0-7656CcmCDE protoheme IX reservoir complexIntegral Inner Membrane (B)CCME_ECOLI
CCMD_ECOLI
CCMC_ECOLI
P69490
P0ABM5
P0ABM1
[CcmD][CcmE][CcmC]
step1349CPLX0-3323CcmEFGH holocytochrome c synthetaseIntegral Inner Membrane (B)CCME_ECOLI
CCMF_ECOLI
CCMH_ECOLI
P69490
P33927
P0ABM9
[CcmE][CcmF][CcmG][CcmH]
step2104N/ACell division complex FtsZ-OpgHPeripheral inner membrane protein facing the cytoplasm (F1)FTSZ_ECOLI
OPGH_ECOLI
P0A9A6
P62517
[FtsZ][OpgH]
step1994N/Acell division complex LpoB-PbpBB&ILPOB_ECOLI
PBPB_ECOLI
P02919
P0AB38
[LpoB][PbpB]
step1450CPLX0-7538cell division factor ZapA, localizes to the cytokineticringPeripheral inner membrane protein facing the cytoplasm (F1)ZAPA_ECOLIP0ADS2[ZapA]4
step1507CPLX0-7686cell division factor ZapBPeripheral inner membrane protein facing the cytoplasm (F1)ZAPB_ECOLIP0AF36[ZapB]2
step2025CPLX0-7973cell division factor ZapDCytoplasmic (A)ZAPD_ECOLIP36680[ZapD]2
step2103N/ACell division inhibition complex FtsZ-SulAPeripheral inner membrane protein facing the cytoplasm (F1)SULA_ECOLI
FTSZ_ECOLI
P0A9A6
P0AFZ5
[FtsZ]2[SulA]2
step1622CPLX0-7922cell division inhibitor, nucleoid occlusionNucleoid (N)SLMA_ECOLIP0C093[SlmA]2
step1515CPLX0-7696cell division protein involved in chromosome partitioningN,F1MUKB_ECOLIP22523[MukB]2
step2131N/ACell envelope and the maintenance complex of YhcB with RodZIntegral Inner Membrane (B)YHCB_ECOLI
RODZ_ECOLI
P0ADW3
P27434
[YhcB][RodZ]
step1317CPLX0-2802chaperone with DnaK; curved DNA-binding proteinPeripheral inner membrane protein facing the cytoplasm (F1)CBPA_ECOLIP36659[CbpA]2
step1649CPLX0-7960chaperone, protecting proteins in response to oxidativestressCytoplasmic (A)YAJL_ECOLIQ46948[YajL]2
step1172CHEA-CPLXCheA(L) histidine kinaseCytoplasmic (A)CHEA_ECOLIP07363[CheA]2
step1173CHEZ-CPLXCheZCytoplasmic (A)CHEZ_ECOLIP0A9H9[CheZ]2
step1184CPLX-155chitobiose PTS permeaseIntegral Inner Membrane (B)PTQC_ECOLI
PTQB_ECOLI
PTQA_ECOLI
P17334
P69795
P69791
[ChbA][ChbC]2[ChbB]
step1650CPLX0-7961chloride:H+ antiporter ClcAIntegral Inner Membrane (B)CLCA_ECOLIP37019[ClcA]2
step1174CHORISMUTPREPHENDEHYDRAT-CPLXchorismate mutase / prephenate dehydrataseCytoplasmic (A)PHEA_ECOLIP0A9J8[PheA]2
step1175CHORISMUTPREPHENDEHYDROG-CPLXchorismate mutase / prephenate dehydrogenaseCytoplasmic (A)TYRA_ECOLIP07023[TyrA]2
step1134AROC-CPLXchorismate synthaseCytoplasmic (A)AROC_ECOLIP12008[AroC]4
step1451CPLX0-7561ChpB-ChpS complexNucleoid (N)CHPS_ECOLI
CHPB_ECOLI
P08365
P33647
[ChpB][ChpS]
step1337CPLX0-3121chromate reductaseCytoplasmic (A)YIEF_ECOLIP0AGE6[YieF]2
step1102ACPSUB-CPLXcitrate lyase [acyl carrier protein] componentCytoplasmic (A)CITD_ECOLIP69330[CitD]6
step1179CITTRANS-CPLXcitrate lyase, citrate-ACP transferase componentCytoplasmic (A)CILA_ECOLIP75726[CitF]6
step1178CITRYLY-CPLXcitrate lyase, citryl-ACP lyase componentCytoplasmic (A)CITE_ECOLIP0A9I1[CitE]6
step1176CITLY-CPLXcitrate lyase, inactiveCytoplasmic (A)CILA_ECOLI
CITE_ECOLI
CITD_ECOLI
P75726
P0A9I1
P69330
[(CitD)6][(CitF)6][(CitE)6]
step1177CITRATE-SI-SYNTHASEcitrate synthaseCytoplasmic (A)CISY_ECOLIP0ABH7[GltA]6
step1659CPLX0-881ClpA ATP-dependent protease specificity component andchaperoneCytoplasmic (A)CLPA_ECOLIP0ABH9[ClpA]6
step1334CPLX0-3104ClpAPCytoplasmic (A)CLPA_ECOLI
CLPP_ECOLI
P0ABH9
P0A6G7
[(ClpP)14][(ClpA)6]2
step1336CPLX0-3108ClpAXPCytoplasmic (A)CLPA_ECOLI
CLPX_ECOLI
CLPP_ECOLI
P0ABH9
P0A6H1
P0A6G7
[(ClpP)14][(ClpA)6][(ClpX)6]
step1332CPLX0-3101ClpP serine proteaseCytoplasmic (A)CLPP_ECOLIP0A6G7[ClpP]14
step1333CPLX0-3102ClpX ATP-dependent protease specificity component andchaperoneCytoplasmic (A)CLPX_ECOLIP0A6H1[ClpX]6
step1335CPLX0-3107ClpXPCytoplasmic (A)CLPX_ECOLI
CLPP_ECOLI
P0A6H1
P0A6G7
[(ClpP)14][(ClpX)6]2
step1316CPLX0-2681ClpXP protease specificity-enhancing factorCytoplasmic (A)SSPB_ECOLIP0AFZ3[SspB]2
step1181COBU-CPLXcobinamide-P guanylyltransferase / cobinamide kinaseCytoplasmic (A)COBU_ECOLIP0AE76[CobU]2
step1271CPLX0-2202Colicin S4 Transport SystemProtein complex spanning both membranesTOLR_ECOLI
PAL_ECOLI
TOLA_ECOLI
TOLB_ECOLI
OMPW_ECOLI
YBGF_ECOLI
TOLQ_ECOLI
P0ABV6
P0A912
P19934
P0A855
P0A915
P45955
P0ABU9
[(TolA)(TolQ)(TolR)(TolB)(YbgF)(Pal)][OmpW]
step1455CPLX0-7609complex involved in modification of tRNAPeripheral inner membrane protein facing the cytoplasm (F1)MNME_ECOLI
MNMG_ECOLI
P25522
P0A6U3
[(MnmE)2][(MnmG)2]
step2143N/AComplex of DmsD and DmsA potentially involved in the molybdopterin cofactor biosynthesis.Peripheral inner membrane protein facing the cytoplasm (F1)DMSA_ECOLI
DMSD_ECOLI
P69853
P18775
[DmsD][DmsA]
step2148N/AComplex of DmsD and MobA potentially involved in the molybdopterin cofactor biosynthesis.Peripheral inner membrane protein facing the cytoplasm (F1)MOBA_ECOLI
DMSD_ECOLI
P69853
P32173
[DmsD][MobA]
step2149N/AComplex of DmsD and MobB potentially involved in the molybdopterin cofactor biosynthesis.Peripheral inner membrane protein facing the cytoplasm (F1)MOBB_ECOLI
DMSD_ECOLI
P69853
P32125
[DmsD][MobB]
step2146N/AComplex of DmsD and MoeA potentially involved in the molybdopterin cofactor biosynthesis.Peripheral inner membrane protein facing the cytoplasm (F1)MOEA_ECOLI
DMSD_ECOLI
P69853
P12281
[DmsD][MoeA]
step2147N/AComplex of DmsD and MoeB potentially involved in the molybdopterin cofactor biosynthesis.Peripheral inner membrane protein facing the cytoplasm (F1)MOEB_ECOLI
DMSD_ECOLI
P69853
P12282
[DmsD][MoeB]
step2145N/AComplex of DmsD and Mog potentially involved in the molybdopterin cofactor biosynthesis.Peripheral inner membrane protein facing the cytoplasm (F1)MOG_ECOLI
DMSD_ECOLI
P69853
P0AF03
[DmsD][Mog]
step2090N/AComplex of SeqA with unkown factor SeqB.Nucleoid (N)SEQA_ECOLI
SEQB_ECOLI
P0AFY8[SeqA][SeqB]
step2150N/AComplex that interrupts cell division and cell growth.Peripheral inner membrane protein facing the cytoplasm (F1)NLPI_ECOLI
IBPA_ECOLI
IBPB_ECOLI
P0C054
P0AFB1
P0C058
[NlpI][IbpA][IbpB]
step1351CPLX0-3362connecting fragment of NADH dehydrogenase IPeripheral inner membrane protein facing the cytoplasm (F1)NUOCD_ECOLI
NUOB_ECOLI
NUOI_ECOLI
P33599
P0AFC7
P0AFD6
[NuoB][NuoC][NuoI]
step1578CPLX0-7816conserved DNA-binding proteinCytoplasmic (A)YBAB_ECOLIP0A8B5[YbaB]2
step1252CPLX0-1863conserved metal-binding proteinCytoplasmic (A)YBGI_ECOLIP0AFP6[YbgI]6
step1247CPLX0-1721copper / silver efflux transport systemProtein complex spanning both membranesCUSC_ECOLI
CUSB_ECOLI
CUSA_ECOLI
CUSF_ECOLI
P77211
P77239
P38054
P77214
[CusC]3[CusB]6[CusF][CusA]3
step1394CPLX0-3938copper binding protein CutACytoplasmic (A)CUTA_ECOLIP69488[CutA]3
step1120AMINEOXID-CPLXcopper-containing amine oxidasePeriplasmic (G)AMO_ECOLIP46883[TynA]2
step1575CPLX0-7808coproporphyrinogen III oxidaseCytoplasmic (A)HEM6_ECOLIP36553[HemF]2
step2026CPLX0-8095CP4-57 prophage; RNase LS, toxin of the RnlAB toxin-antitoxin systemCytoplasmic (A)RNLA_ECOLIP52129[RnlA]2
step1634CPLX0-7940CP4-6 prophage; probable 2-keto-3-deoxygluconate aldolaseCytoplasmic (A)YAGE_ECOLIP75682[YagE]4
step1548CPLX0-7748CpxR-Pasp DNA-binding transcriptional dual regulatorN,F1CPXR_ECOLIP0AE88[CpxR]2
step1864PC00061Cra DNA-binding transcriptional dual regulatorNucleoid (N)CRA_ECOLIP0ACP1[FruR]4
step1666CREC-CPLXCreC sensory histidine kinaseIntegral Inner Membrane (B)CREC_ECOLIP08401[CreC]2
step1535CPLX0-7725CRISPR-associated complex for antiviral defenseIntegral Inner Membrane (B)CAS6_ECOLI
CASC_ECOLI
CSE2_ECOLI
CAS5_ECOLI
CSE1_ECOLI
Q46897
Q46899
P76632
Q46898
Q46901
[YgcL][YgcK]2[YgcJ]6[YgcI][YgcH]
step1857PC00004CRP transcriptional dual regulatorN,F1CRP_ECOLIP0ACJ8[Crp]2
step1246CPLX0-1683cryptic adenine deaminaseCytoplasmic (A)ADEC_ECOLIP31441[Ade]2
step1592CPLX0-7839CSD sulfur transfer proteinCytoplasmic (A)YGDK_ECOLIP0AGF2[YgdK]2
step1645CPLX0-7956CsrA dimerCytoplasmic (A)CSRA_ECOLIP69913[CsrA]2
step1667CTPSYN-CPLXCTP synthetasePeripheral inner membrane protein facing the cytoplasm (F1)PYRG_ECOLIP0A7E5[PyrG]4
step1521CPLX0-7708CueR-Cu+ DNA-binding transcriptional dual regulatorNucleoid (N)CUER_ECOLIP0A9G4[(CueR)(Cu+)]2
step1201CPLX-3945curli secretion and assembly complexH&F4CSGG_ECOLI
CSGE_ECOLI
CSGF_ECOLI
P0AEA2
P0AE95
P0AE98
[CsgG][CsgE][CsgF]
step1668CYANLY-CPLXcyanaseCytoplasmic (A)CYNS_ECOLIP00816[(CynS)2]5
step2027CPLX0-7520cyanaseCytoplasmic (A)CYNS_ECOLIP00816[(CynS)2]5
step1171CFA-CPLXcyclopropane fatty acyl phospholipid synthaseCytoplasmic (A)CFA_ECOLIP0A9H7[Cfa]2
step1863PC00040CysB transcriptional dual regulatorN,F1CYSB_ECOLIP0A9F3[CysB]4
step1301CPLX0-248cysteine desulfuraseCytoplasmic (A)ISCS_ECOLIP0A6B7[IscS]2
step1591CPLX0-7838cysteine sulfinate desulfinasePeripheral inner membrane protein facing the cytoplasm (F1)CSDA_ECOLIQ46925[CsdA]2
step1103ACSERLYA-CPLXcysteine synthase ACytoplasmic (A)CYSK_ECOLIP0ABK5[CysK]2
step1104ACSERLYB-CPLXcysteine synthase BCytoplasmic (A)CYSM_ECOLIP16703[CysM]2
step1673CYTIDEAM-CPLXcytidine deaminaseCytoplasmic (A)CDD_ECOLIP0ABF6[Cdd]2
step1671CYT-D-UBIOX-CPLXcytochrome bd-I terminal oxidaseIntegral Inner Membrane (B)CYDB_ECOLI
CYDA_ECOLI
P0ABK2
P0ABJ9
[CydA][CydB]
step1129APP-UBIOX-CPLXcytochrome bd-II terminal oxidaseIntegral Inner Membrane (B)APPB_ECOLI
APPC_ECOLI
P26458
P26459
[AppC][AppB]
step1672CYT-O-UBIOX-CPLXcytochrome bo terminal oxidaseB&ECYOC_ECOLI
CYOB_ECOLI
CYOD_ECOLI
CYOA_ECOLI
P0ABJ3
P0ABI8
P0ABJ6
P0ABJ1
[CyoD][CyoA][CyoB][CyoC]
step1627CPLX0-7932cytosine deaminaseCytoplasmic (A)CODA_ECOLIP25524[CodA]6
step1543CPLX0-7740CytR DNA-binding transcriptional repressorCytoplasmic (A)CYTR_ECOLIP0ACN7[CytR]2
step1674DALADALALIGB-CPLXD-alanine-D-alanine ligase BCytoplasmic (A)DDLB_ECOLIP07862[DdlB]2
step1066ABC-42-CPLXD-allose ABC transporterIntegral Inner Membrane (B)ALSC_ECOLI
ALSB_ECOLI
ALSA_ECOLI
P32720
P39265
P32721
[AlsA]2[AlsC]2[AlsB]
step1675DALADEHYDROG-CPLXD-amino acid dehydrogenasePeripheral inner membrane protein facing the cytoplasm (F1)DADA_ECOLIP0A6J5[DadA]2
step1386CPLX0-3929D-arabinose 5-phosphate isomeraseCytoplasmic (A)GUTQ_ECOLIP17115[GutQ]4
step1227CPLX0-1262D-arabinose 5-phosphate isomeraseCytoplasmic (A)KDSD_ECOLIP45395[KdsD]4
step1678DCYSDESULF-CPLXD-cysteine desulfhydrase, PLP-dependent / 3-chloro-D-alanine dehydrochlorinaseCytoplasmic (A)DCYD_ECOLIP76316[DcyD]2
step1751GLUCONOKINII-CPLXD-gluconate kinase, thermostableCytoplasmic (A)GNTK_ECOLIP46859[GntK]3
step1492CPLX0-7660D-sedoheptulose 7-phosphate isomeraseCytoplasmic (A)GMHA_ECOLIP63224[GmhA]4
step1361CPLX0-3581D-Tyr-tRNATyr deacylaseCytoplasmic (A)DTD_ECOLIP0A6M4[Dtd]2
step1466CPLX0-7625dCMP phosphohydrolaseCytoplasmic (A)YFBR_ECOLIP76491[YfbR]2
step1677DCTP-DEAM-CPLXdCTP deaminaseCytoplasmic (A)DCD_ECOLIP28248[Dcd]3
step1531CPLX0-7721DcuR-Phosphorylated DNA-binding transcriptional activatorNucleoid (N)DCUR_ECOLIP0AD01[DcuR]2
step1288CPLX0-2381degradosomePeripheral inner membrane protein facing the cytoplasm (F1)RNE_ECOLI
ENO_ECOLI
PNP_ECOLI
PPK_ECOLI
RHLB_ECOLI
P21513
P0A6P9
P05055
P0A7B1
P0A8J8
[(Ppk)4][(Rne)4][(RhlB)2][(Pnp)3][(Eno)2]
step1682DGTPTRIPHYDRO-CPLXdeoxyguanosine triphosphate triphosphohydrolaseCytoplasmic (A)DGTP_ECOLIP15723[Dgt]4
step1699DUTP-PYROP-CPLXdeoxyuridine triphosphataseCytoplasmic (A)DUT_ECOLIP06968[Dut]3
step1681DETHIOBIOTIN-SYN-CPLXdethiobiotin synthetaseCytoplasmic (A)BIOD1_ECOLIP13000[BioD1]2
step1685DIACYLGLYKIN-CPLXdiacylglycerol kinaseIntegral Inner Membrane (B)KDGL_ECOLIP0ABN1[DgkA]3
step1686DIAMINOPIMDECARB-CPLXdiaminopimelate decarboxylaseCytoplasmic (A)DCDA_ECOLIP00861[LysA]4
step2028CPLX0-7997diaminopimelate epimeraseCytoplasmic (A)DAPF_ECOLIP0A6K1[DapF]2
step1571CPLX0-7802diguanylate cyclaseCytoplasmic (A)YDEH_ECOLIP31129[YdeH]2
step2029CPLX0-8090diguanylate cyclaseCytoplasmic (A)YDAM_ECOLIP77302[YdaM]4
step1689DIHYDROPICRED-CPLXdihydrodipicolinate reductaseCytoplasmic (A)DAPB_ECOLIP04036[DapB]4
step1687DIHYDRODIPICSYN-CPLXdihydrodipicolinate synthaseCytoplasmic (A)DAPA_ECOLIP0A6L2[DapA]4
step1703E2OdihydrolipoyltranssuccinylaseCytoplasmic (A)ODO2_ECOLIP0AFG6[Odo2]24
step1392CPLX0-3936dihydroneopterin aldolaseCytoplasmic (A)FOLB_ECOLIP0AC16[FolB]8
step1728FOLXTET-CPLXdihydroneopterin triphosphate 2'-epimeraseCytoplasmic (A)FOLX_ECOLIP0AC19[FolX]8
step1688DIHYDROOROT-CPLXdihydroorotaseCytoplasmic (A)PYRC_ECOLIP05020[PyrC]2
step1690DIHYDROPTERIREDUCT-CPLXdihydropteridine reductaseCytoplasmic (A)NFNB_ECOLIP38489[nfnB]2
step1782H2PTEROATESYNTH-CPLXdihydropteroate synthaseCytoplasmic (A)DHPS_ECOLIP0AC13[FolP]2
step1691DIHYDROXYACIDDEHYDRAT-CPLXdihydroxy acid dehydrataseCytoplasmic (A)ILVD_ECOLIP05791[IlvD]2
step1266CPLX0-2081dihydroxyacetone kinasePeripheral inner membrane protein facing the cytoplasm (F1)DHAM_ECOLI
DHAK_ECOLI
DHAL_ECOLI
P37349
P76015
P76014
[DhaM]2[DhaK]2[DhaL]
step1835NIRB-CPLXdimer of large subunit of nitrite reductaseCytoplasmic (A)NIRB_ECOLIP08201[NirB]2
step1293CPLX0-2423dimer of topoisomerase IV subunit APeripheral inner membrane protein facing the cytoplasm (F1)PARC_ECOLIP0AFI2[ParC]2
step1692DIMESULFREDUCT-CPLXdimethyl sulfoxide reductaseIntegral Inner Membrane (B)DMSA_ECOLI
DMSC_ECOLI
DMSB_ECOLI
P18775
P18777
P18776
[DmsA][DmsB][DmsC]
step1559CPLX0-7787DinJ-YafQ antitoxin/toxin complex and DNA-binding transcriptional repressorNucleoid (N)YAFQ_ECOLI
DINJ_ECOLI
Q47149
Q47150
[YafQ][DinJ]
step1089ABC-8-CPLXdipeptide ABC transporterIntegral Inner Membrane (B)DPPD_ECOLI
DPPB_ECOLI
DPPC_ECOLI
DPPA_ECOLI
DPPF_ECOLI
P0AAG0
P0AEF8
P0AEG1
P23847
P37313
[DppD][DppF][DppB][DppC][DppA]
step1573CPLX0-7806disulfide reductaseCytoplasmic (A)YFCG_ECOLIP77526[YfcG]2
step1620CPLX0-7917disulfide reductase / organic hydroperoxide reductasePeripheral inner membrane protein facing the cytoplasm (F1)YGHU_ECOLIQ46845[YghU]2
step1586CPLX0-7826dITP/XTP pyrophosphataseCytoplasmic (A)RDGB_ECOLIP52061[RdgB]2
step1295CPLX0-2425DNA gyraseCytoplasmic (A)GYRA_ECOLI
GYRB_ECOLI
P0AES4
P0AES6
[GyrA]2[GyrB]2
step1285CPLX0-2361DNA polymerase III, core enzymeNucleoid (N)HOLE_ECOLI
DPO3A_ECOLI
DPO3E_ECOLI
P0ABS8
P10443
P03007
[DnaE][DnaQ][HolE]
step1374CPLX0-3803DNA polymerase III, holoenzymeNucleoid (N)HOLE_ECOLI
DPO3X_ECOLI
HOLD_ECOLI
HOLC_ECOLI
HOLB_ECOLI
HOLA_ECOLI
DPO3B_ECOLI
DPO3A_ECOLI
DPO3E_ECOLI
P0ABS8
P06710
P28632
P28905
P28631
P28630
P0A988
P10443
P03007
[(DnaE)(DnaQ)(HolE)]3[(DnaX)3(HolB)(HolA)][(DnaN)2]2[(DnaX)2][(HolC)(HolD)]4
step1372CPLX0-3801DNA polymerase III, preinitiation complexNucleoid (N)DPO3X_ECOLI
HOLB_ECOLI
HOLA_ECOLI
P06710
P28631
P28630
[DnaX]3[HolB][HolA]
step1370CPLX0-3761DNA polymerase III, β subunitNucleoid (N)DPO3B_ECOLIP0A988[DnaN]2
step1373CPLX0-3802DNA polymerase III, τ subunit dimerNucleoid (N)DPO3X_ECOLIP06710[DnaX]2
step1615CPLX0-7910DNA polymerase III, ψ-χ subunitNucleoid (N)HOLD_ECOLI
HOLC_ECOLI
P28632
P28905
[HolC][HolD]
step1384CPLX0-3925DNA polymerase VNucleoid (N)UMUC_ECOLI
UMUD_ECOLI
P04152
P0AG11
[UmuC][UmuD]2
step1348CPLX0-3301DNA replication inhibitorCytoplasmic (A)CSPD_ECOLIP0A968[CspD]2
step1319CPLX0-2881DNA-binding, ATP-dependent protease LaCytoplasmic (A)LON_ECOLIP0A9M0[Lon]4
step1344CPLX0-3221DnaA initiator-associating factor for replicationinitiationN,F1DNAA_ECOLI
DIAA_ECOLI
P03004
P66817
[DiaA]2
step1791HSP70-CPLXDnaJ/DnaK/GrpEPeripheral inner membrane protein facing the cytoplasm (F1)GRPE_ECOLI
DNAK_ECOLI
DNAJ_ECOLI
P09372
P0A6Y8
P08622
[DnaJ][DnaK][GrpE]
step1212CPLX0-0DnaTCytoplasmic (A)DNAT_ECOLIP0A8J2[DnaT]3
step1989N/Adodecamer of pore-forming cytotoxin HlyEExtra-cellular (X)HLYE_ECOLIP77335[HlyE]12
step1584CPLX0-7823DosC-DosP complexCytoplasmic (A)DOSP_ECOLI
DOSC_ECOLI
P76129
P0AA89
[DosP][DosC]
step1235CPLX0-1521Dps complex; stationary phase nucleoid component that sequesters iron and protects DNA from damageN,F1DPS_ECOLIP0ABT2[Dps]12
step2030CPLX0-8004DsbGoxidizedPeriplasmic (G)DSBG_ECOLIP77202[DsbG]2
step1526CPLX0-7713DsdC DNA-binding transcriptional dual regulatorNucleoid (N)DSDC_ECOLIP46068[DsdC]2
step2031CPLX0-7990dTDP-4-dehydro-6-deoxy-D-glucose transaminaseCytoplasmic (A)RFFA_ECOLIP27833[RffA]4
step1697DTDPGLUCDEHYDRAT-CPLXdTDP-glucose 4,6-dehydrataseCytoplasmic (A)RMLB1_ECOLIP37759[RfbB]2
step2032CPLX0-8012dTDP-glucose pyrophosphorylaseCytoplasmic (A)RMLA2_ECOLIP61887[RffH]4
step2033CPLX0-8034dTDP-glucose pyrophosphorylaseCytoplasmic (A)RFFA_ECOLIP27833[RfbA]4
step1698DTDPRHAMSYNTHMULTI-CPLXdTDP-L-rhamnose synthetaseCytoplasmic (A)RMLD_ECOLI
RMLC_ECOLI
P37760
P37745
[RfbC][RfbD]
step1408CPLX0-3958EcoKI restriction-modification systemCytoplasmic (A)T1SK_ECOLI
T1MK_ECOLI
T1RK_ECOLI
P05719
P08957
P08956
[HsdM]2[HsdR]2[HsdS]
step1233CPLX0-1441ecotin homodimer; serine protease inhibitorPeriplasmic (G)ECOT_ECOLIP23827[Eco]2
step1610CPLX0-7889EF-P-lysine lysyltransferaseCytoplasmic (A)EPMA_ECOLIP0A8N7[PoxA]2
step1576CPLX0-7810EfeB dimerPeriplasmic (G)EFEB_ECOLIP31545[EfeB]2
step1479CPLX0-7644EfeU/EfeO/EfeB ferrous iron transporter; crypticIntegral Inner Membrane (B)EFEU_ECOLI
EFEB_ECOLI
EFEO_ECOLI
P75901
P31545
P0AB24
[EfeU_1][EfeO]
step1267CPLX0-2121EmrAB-TolC multidrug efflux transport systemProtein complex spanning both membranesTOLC_ECOLI
EMRA_ECOLI
EMRB_ECOLI
P02930
P27303
P0AEJ0
[EmrA][EmrB][(TolC)3]
step1269CPLX0-2161EmrKY-TolC multidrug efflux transport systemProtein complex spanning both membranesEMRY_ECOLI
TOLC_ECOLI
EMRK_ECOLI
P52600
P02930
P52599
[EmrK][EmrY][(TolC)3]
step1708ENOLASE-CPLXenolasePeripheral inner membrane protein facing the cytoplasm (F1)ENO_ECOLIP0A6P9[Eno]2
step2034CPLX0-8006enoyl-[acyl-carrier-protein] reductasePeripheral inner membrane protein facing the cytoplasm (F1)FABI_ECOLIP0AEK4[FabI]4
step1705ECNAB-CPLXentericidin toxin-antitoxin complexOuter Membrane Lipoprotein (I)ECNB_ECOLI
ECNA_ECOLI
P0ADB7
P0ADB4
[EcnB][EcnA]
step1415CPLX0-3976Enterobacterial common antigen biosynthesis protein complexIntegral Inner Membrane (B)WZYE_ECOLI
WZZE_ECOLI
WZXE_ECOLI
P27835
P0AG00
P0AAA7
[WzxE][WzyE][WzzE]
step1711ENTMULTI-CPLXenterobactin synthase multienzyme complexPeripheral inner membrane protein facing the cytoplasm (F1)ENTE_ECOLI
ENTD_ECOLI
ENTF_ECOLI
P10378
P19925
P11454
[EntBisochorismatase/aryl-carrierprotein][EntD][EntF][(EntE)2]
step1417CPLX0-5EntS-TolC Enterobactin Efflux Transport SystemProtein complex spanning both membranesTOLC_ECOLI
ENTS_ECOLI
P02930
P24077
[EntS][(TolC)3]
step1712ENVZ-CPLXEnvZ sensory histidine kinaseIntegral Inner Membrane (B)ENVZ_ECOLIP0AEJ4[EnvZ]2
step1713ERYTH4PDEHYDROG-CPLXerythrose 4-phosphate dehydrogenaseCytoplasmic (A)E4PD_ECOLIP0A9B6[Epd]4
step1567CPLX0-7798essential protein with weak ATPase activityCytoplasmic (A)YJEE_ECOLIP0AF67[YjeE]2
step1462CPLX0-7617essential respiratory protein ACytoplasmic (A)ERPA_ECOLIP0ACC3[ErpA]2
step2035CPLX0-8015ethanol dehydrogenase / alcohol dehydrogenaseA/F1ADHP_ECOLIP39451[AdhP]4
step1714ETHAMLY-CPLXethanolamine ammonia-lyaseCytoplasmic (A)EUTC_ECOLI
EUTB_ECOLI
P19636
P0AEJ6
[EutB]6[EutC]6
step1393CPLX0-3937evolved β-D-galactosidaseCytoplasmic (A)BGA2_ECOLI
EBGC_ECOLI
P06864
P0AC73
[EbgA]4[EbgC]4
step2116N/AExbB-ExbD complexIntegral Inner Membrane (B)EXBB_ECOLI
EXBD_ECOLI
P0ABU7
P0ABV2
[ExbB]4[ExbD]2
step1202CPLX-3946exonuclease VIICytoplasmic (A)EX7L_ECOLI
EX7S_ECOLI
P04994
P0A8G9
[XseA][XseB]4
step1890PPX-CPLXexopolyphosphatasePeripheral inner membrane protein facing the cytoplasm (F1)PPX_ECOLIP0AFL6[Ppx]2
step1243CPLX0-1667Fad I component of anaerobic fatty acid oxidationcomplexCytoplasmic (A)FADI_ECOLIP76503[FadI]2
step1242CPLX0-1666FadJ component of anaerobic fatty acid oxidation complexCytoplasmic (A)FADJ_ECOLIP77399[FadJ]2
step2015N/AFadL homodimerOuter Membrane b-barrel (H)FADL_ECOLIP10384[FadL]2
step1721FADA-CPLXfatty acid oxidation complex, α componentCytoplasmic (A)FADA_ECOLIP21151[FadA]2
step1722FADB-CPLXfatty acid oxidation complex, γ componentCytoplasmic (A)FADB_ECOLIP21177[FadB]2
step1105ACYLCOASYN-CPLXfatty acyl-CoA synthetasePeripheral inner membrane protein facing the cytoplasm (F1)LCFA_ECOLIP69451[FadD]2
step1476CPLX0-7641Fe(2+):H+ antiporter [multifunctional]Integral Inner Membrane (B)FIEF_ECOLIP69380[FieF]2
step1585CPLX0-7824Fe-S transport protein in Fe-S cluster assemblyPeripheral inner membrane protein facing the cytoplasm (F1)SUFA_ECOLIP77667[SufA]2
step1200CPLX-3944FecAR Signal Transduction SystemProtein complex spanning both membranesFECA_ECOLI
FECR_ECOLI
P13036
P23485
[FecA][FecR]
step1258CPLX0-1943ferric citrate outer membrane transport complexProtein complex spanning both membranesEXBD_ECOLI
TONB_ECOLI
FECA_ECOLI
EXBB_ECOLI
P0ABV2
P02929
P13036
P0ABU7
[FecA][(TonB)(ExbB)(ExbD)]
step1642CPLX0-7952ferric coprogen outer membrane transport complexProtein complex spanning both membranesEXBD_ECOLI
TONB_ECOLI
FHUE_ECOLI
EXBB_ECOLI
P0ABV2
P02929
P16869
P0ABU7
[FhuE][(TonB)(ExbB)(ExbD)]
step1643CPLX0-7954ferric coprogen transport systemProtein complex spanning both membranesEXBD_ECOLI
TONB_ECOLI
FHUC_ECOLI
FHUB_ECOLI
FHUE_ECOLI
FHUD_ECOLI
EXBB_ECOLI
P0ABV2
P02929
P07821
P06972
P16869
P07822
P0ABU7
[(FhuC)2(FhuB)2(FhuD)][(FhuE)([TonB][ExbB][ExbD])]
step1090ABC-9-CPLXferric dicitrate ABC transporterIntegral Inner Membrane (B)FECB_ECOLI
FECC_ECOLI
FECD_ECOLI
FECE_ECOLI
P15028
P15030
d
P15031
[FecE]2[FecC][FecD][FecB]
step1262CPLX0-2001ferric dicitrate transport systemProtein complex spanning both membranesFECB_ECOLI
EXBD_ECOLI
TONB_ECOLI
FECA_ECOLI
FECC_ECOLI
FECD_ECOLI
FECE_ECOLI
EXBB_ECOLI
P15028
P0ABV2
P02929
P13036
P15030
P15029
P15031
P0ABU7
[(FecE)2(FecC)(FecD)(FecB)][(FecA)([TonB][ExbB][ExbD])]
step1036ABC-10-CPLXferric enterobactin ABC transporterIntegral Inner Membrane (B)FEPB_ECOLI
FEPC_ECOLI
FEPG_ECOLI
FEPD_ECOLI
P0AEL6
P23878
P23877
P23876
[FepC]2[FepD][FepG][FepB]
step1256CPLX0-1941ferric enterobactin outer membrane transport complexProtein complex spanning both membranesEXBD_ECOLI
TONB_ECOLI
FEPA_ECOLI
EXBB_ECOLI
P0ABV2
P02929
P05825
P0ABU7
[(TonB)(ExbB)(ExbD)][FepA]
step1259CPLX0-1944ferric enterobactin transport systemProtein complex spanning both membranesFEPG_ECOLI
EXBD_ECOLI
TONB_ECOLI
FEPD_ECOLI
FEPB_ECOLI
FEPA_ECOLI
FEPC_ECOLI
EXBB_ECOLI
P23877
P0ABV2
P02929
P23876
P0AEL6
P05825
P23878
P0ABU7
[(FepC)2(FepD)(FepG)(FepB)][([TonB][ExbB][ExbD])(FepA)]
step1257CPLX0-1942ferrichrome outer membrane transport complexProtein complex spanning both membranesEXBD_ECOLI
TONB_ECOLI
FHUA_ECOLI
EXBB_ECOLI
P0ABV2
P02929
P06971
P0ABU7
[(TonB)(ExbB)(ExbD)][FhuA]
step1261CPLX0-1981ferrichrome transport systemProtein complex spanning both membranesEXBD_ECOLI
TONB_ECOLI
FHUA_ECOLI
FHUC_ECOLI
FHUB_ECOLI
FHUD_ECOLI
EXBB_ECOLI
P0ABV2
P02929
P06971
P07821
P06972
P07822
P0ABU7
[(FhuC)2(FhuB)2(FhuD)][([TonB][ExbB][ExbD])(FhuA)]
step1412CPLX0-3969ferritin iron-storage complexCytoplasmic (A)FTNA_ECOLIP0A998[FtnA]24
step1353CPLX0-3401fimbrial complexPeripheral outer membrane protein facing the extra-cellular space (F4)FIMA1_ECOLI
FIMF_ECOLI
FIMG_ECOLI
FIMH_ECOLI
P04128
P08189
P08190
P08191
[FimA][FimF][FimG][FimH]
step1519CPLX0-7705Fis DNA-binding transcriptional dual regulatorN,F1FIS_ECOLIP0A6R3[Fis]2
step1449CPLX0-7536FKBP-type peptidyl prolyl cis-trans isomeraseCytoplasmic (A)SLYD_ECOLIP0A9K9[SlyD]2
step1383CPLX0-3924FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase)Cytoplasmic (A)FKBB_ECOLIP0A9L3[FklB]2
step1435CPLX0-7451Flagellar Export ApparatusIntegral Inner Membrane (B)FLIJ_ECOLI
FLIR_ECOLI
FLII_ECOLI
FLHA_ECOLI
FLHB_ECOLI
FLIH_ECOLI
FLIO_ECOLI
FLIQ_ECOLI
FLIP_ECOLI
P52613
P33135
P52612
P76298
P76299
P31068
P22586
P0AC07
P0AC05
[FlhA][FlhB][FliO][FliP][FliQ][FliR][FliH]12[FliI]6[FliJ]
step1725FLAGELLAR-MOTOR-COMPLEXFlagellar Motor ComplexB&IMOTB_ECOLI
FLIE_ECOLI
FLIM_ECOLI
MOTA_ECOLI
FLGI_ECOLI
FLIG_ECOLI
FLGB_ECOLI
FLGC_ECOLI
FLIN_ECOLI
FLIF_ECOLI
FLGH_ECOLI
FLGG_ECOLI
FLGF_ECOLI
P0AF06
P0A8T5
P06974
P09348
P0A6S3
P0ABZ1
P0ABW9
P0ABX2
P15070
P25798
P0A6S0
P0ABX5
P75938
[(FliG)26(FliM)34(FliN)][FlgH][MotA][MotB][FlgB][FlgC][FlgF][FlgG][FlgI][FliF][FliE]
step1434CPLX0-7450Flagellar Motor Switch ComplexPeripheral inner membrane protein facing the cytoplasm (F1)FLIM_ECOLI
FLIG_ECOLI
FLIN_ECOLI
P06974
P0ABZ1
P15070
[FliG]26[FliM]34[FliN]
step1436CPLX0-7452FlagellumB&H&F4FLGE_ECOLI
FLIJ_ECOLI
FLIR_ECOLI
FLII_ECOLI
FLHA_ECOLI
FLIF_ECOLI
FLGH_ECOLI
FLGG_ECOLI
FLIC_ECOLI
FLGF_ECOLI
MOTB_ECOLI
FLIE_ECOLI
FLGK_ECOLI
FLIM_ECOLI
MOTA_ECOLI
FLGI_ECOLI
FLHB_ECOLI
FLIH_ECOLI
FLGL_ECOLI
FLIG_ECOLI
FLIO_ECOLI
FLIQ_ECOLI
FLGB_ECOLI
FLID_ECOLI
FLGC_ECOLI
FLIP_ECOLI
FLIN_ECOLI
P75937
P52613
P33135
P52612
P76298
P25798
P0A6S0
P0ABX5
P04949
P75938
P0AF06
P0A8T5
P33235
P06974
P09348
P0A6S3
P76299
P31068
P29744
P0ABZ1
P22586
P0AC07
P0ABW9
P24216
P0ABX2
P0AC05
P15070
[([FliG]26[FliM]34[FliN])(FlgH)(MotA)(MotB)(FlgB)(FlgC)(FlgF)(FlgG)(FlgI)(FliF)(FliE)][(FlhA)(FlhB)(FliO)(FliP)(FliQ)(FliR)(FliH)12(FliI)6(FliJ)][FlgE]120[FlgK][FlgL][FliC][FliD]5
step1933N/AFlgN-FlgK-FliJ-FlhA complexPeripheral inner membrane protein facing the cytoplasm (F1)FLGN_ECOLI
FLGK_ECOLI
FLIJ_ECOLI
P43533
P33235
P52613
[FlgN][FlgK][FliJ][FlhA]
step1387CPLX0-3930FlhDC DNA-binding transcriptional dual regulatorNucleoid (N)FLHC_ECOLI
FLHD_ECOLI
P0ABY7
P0A8S9
[FlhD]4[FlhC]2
step1566CPLX0-7797FNR DNA-binding transcriptional dual regulatorNucleoid (N)FNR_ECOLIP0A9E5[Fnr]2
step1594CPLX0-7843FocA formate transporterIntegral Inner Membrane (B)FOCA_ECOLIP0AC23[FocA]5
step1110ADHC-CPLXformaldehyde dehydrogenase, glutathione-dependentCytoplasmic (A)FRMA_ECOLIP25437[FrmA]2
step1534CPLX0-7724formate dehydrogenase formation proteinCytoplasmic (A)FDHE_ECOLIP13024[FdhE]2
step1729FORMATEDEHYDROGN-CPLXformate dehydrogenase-NIntegral Inner Membrane (B)FDNH_ECOLI
FDNI_ECOLI
FDNG_ECOLI
P0AAJ3
P0AEK7
P24183
[(FdnI)(FdnH)(FdnG)]3
step1730FORMATEDEHYDROGO-CPLXformate dehydrogenase-OIntegral Inner Membrane (B)FDOH_ECOLI
FDOG_ECOLI
FDOI_ECOLI
P0AAJ5
P32176
P0AEL0
[FdoG][FdoH][FdoI]
step1724FHLMULTI-CPLXformate hydrogenlyase complexIntegral Inner Membrane (B)HYCB_ECOLI
HYCD_ECOLI
HYCC_ECOLI
HYCE_ECOLI
HYCF_ECOLI
HYCG_ECOLI
FDHF_ECOLI
P0AAK1
P16430
P16429
P16431
P16432
P16433
P07658
[FdhF][(HycD)(HycC)(HycF)(HycG)(HycB)(HycE)]
step1733FORMYLTHFDEFORMYL-CPLXformyl tetrahydrofolate deformylaseCytoplasmic (A)PURU_ECOLIP37051[PurU]6
step1219CPLX0-1142formyl-CoA transferaseA/F1FCTA_ECOLIP69902[Frc]2
step1328CPLX0-303fructose 1,6-bisphosphatase IICytoplasmic (A)GLPX_ECOLIP0A9C9[GlpX]2
step1263CPLX0-201fructose 6-phosphate aldolase 1Cytoplasmic (A)FSAA_ECOLIP78055[FsaA]10
step1734FRUCBISALD-CLASSIfructose bisphosphate aldolase class ICytoplasmic (A)ALF1_ECOLIP0A991[FbaB]10
step1735FRUCBISALD-CLASSIIfructose bisphosphate aldolase class IICytoplasmic (A)ALF_ECOLIP0AB71[FbaA]2
step1187CPLX-158fructose PTS permeaseIntegral Inner Membrane (B)PTFBC_ECOLI
PTFAH_ECOLI
P20966
P69811
[FruB][FruA]2
step1558CPLX0-7776fructose-1,6-bisphosphataseCytoplasmic (A)GLPX2_ECOLIP21437[YggF]2
step1717F16B-CPLXfructose-1,6-bisphosphatase ICytoplasmic (A)F16PA_ECOLIP0A993[Fbp]4
step1377CPLX0-3861fructoselysine 3-epimeraseCytoplasmic (A)FRLC_ECOLIP45541[FrlC]8
step1656CPLX0-821fructoselysine 6-phosphate deglycaseCytoplasmic (A)FRLB_ECOLIP0AC00[FrlB]12
step1075ABC-54-CPLXFtsE/FtsX ABC transporterIntegral Inner Membrane (B)FTSX_ECOLI
FTSE_ECOLI
P0AC30
P0A9R7
[FtsE]2[FtsX]2
step1629CPLX0-7934FtsLBQ cell division complexB&EFTSB_ECOLI
FTSQ_ECOLI
FTSL_ECOLI
P0A6S5
P06136
P0AEN4
[FtsQ][FtsB][FtsL]
step1736FUMARASE-Afumarase ACytoplasmic (A)FUMA_ECOLIP0AC33[FumA]2
step1737FUMARASE-Bfumarase BCytoplasmic (A)FUMB_ECOLIP14407[FumB]2
step1738FUMARASE-Cfumarase CCytoplasmic (A)FUMC_ECOLIP05042[FumC]4
step1739FUMARATE-REDUCTASEfumarate reductaseIntegral Inner Membrane (B)FRDD_ECOLI
FRDC_ECOLI
FRDB_ECOLI
FRDA_ECOLI
P0A8Q3
P0A8Q0
P0AC47
P00363
[FrdA][FrdB][FrdC][FrdD]
step1475CPLX0-7639Fur-Fe+2 DNA-binding transcriptional dual regulatorNucleoid (N)FUR_ECOLIP0A9A9[(Fur)(Fe2+)]2
step1354CPLX0-341fused 4'-phosphopantothenoylcysteine decarboxylase and phosphopantothenoylcysteine synthetaseCytoplasmic (A)COABC_ECOLIP0ABQ0[CoaBC]12
step1491CPLX0-7659fused diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino) uracil reductaseCytoplasmic (A)RIBD_ECOLIP25539[RibD]2
step1778GSP-CPLXfused glutathionylspermidine amidase /glutathionylspermidine synthetaseCytoplasmic (A)GSP_ECOLIP0AES0[Gsp]2
step1366CPLX0-3661fused heptose 7-phosphate kinase/heptose 1-phosphateadenyltransferaseCytoplasmic (A)HLDE_ECOLIP76658[HldE]2
step1829NAG1P-URIDYLTRANS-CPLXfused N-acetylglucosamine-1-phosphate uridyltransferaseand glucosamine-1-phosphate acetyltransferaseCytoplasmic (A)GLMU_ECOLIP0ACC7[GlmU]3
step1898PUTA-CPLXfused PutA DNA-binding transcriptional repressor /proline dehydrogenase / 1-pyrroline-5-carboxylate dehydrogenaseN,F1PUTA_ECOLIP09546[PutA]2
step1598CPLX0-7852GadE-RcsB DNA binding transcriptional activatorN,F1RCSB_ECOLI
GADE_ECOLI
P69407
P63204
[RcsB][GadE]
step1280CPLX0-231galactitol PTS permeaseIntegral Inner Membrane (B)PTKA_ECOLI
PTKB_ECOLI
PTKC_ECOLI
P69828
P37188
P69831
[GatC]2[GatB][GatA]
step1068ABC-46-CPLXgalactofuranose / galactopyranose ABC transporterIntegral Inner Membrane (B)YTFT_ECOLI
YTFQ_ECOLI
YTFR_ECOLI
YJFF_ECOLI
P39328
P39325
Q6BEX0
P37772
[YjfF][YtfR][YtfT]2[YtfQ]
step1197CPLX-170galactosamine PTS permeaseIntegral Inner Membrane (B)PTPC1_ECOLI
PTPB1_ECOLI
PTPD_ECOLI
P42910
P42909
P42911
[AgaB][AgaC]2[AgaD]
step1043ABC-18-CPLXgalactose ABC transporterIntegral Inner Membrane (B)MGLC_ECOLI
MGLA_ECOLI
DGAL_ECOLI
P23200
P0AAG8
P0AEE5
[MglA]2[MglC]2[MglB]
step1742GALACTURIDYLYLTRANS-CPLXgalactose-1-phosphate uridylyltransferaseCytoplasmic (A)GAL7_ECOLIP09148[GalT]2
step1741GALACTOACETYLTRAN-CPLXgalactoside O-acetyltransferaseCytoplasmic (A)THGA_ECOLIP07464[LacA]3
step1599CPLX0-7853GAP-like protein that activates GTPase activity of DerPeripheral inner membrane protein facing the cytoplasm (F1)YIHI_ECOLI
DER_ECOLI
P0A8H6
P0A6P5
[YihI]2
step1865PC00063GatR DNA-binding transcriptional repressorNucleoid (N)GATR_ECOLIP36930[GatR_2][GatR_1]
step1378CPLX0-3881GDP-fucose synthaseCytoplasmic (A)FCL_ECOLIP32055[Fcl]2
step1747GDPMANDEHYDRA-CPLXGDP-mannose 4,6-dehydrataseCytoplasmic (A)GM4D_ECOLIP0AC88[Gmd]2
step1414CPLX0-3971GDP-mannose hydrolaseCytoplasmic (A)NUDK_ECOLIP37128[NudK]2
step1525CPLX0-7712GDP-mannose mannosyl hydrolaseCytoplasmic (A)GMM_ECOLIP32056[Gmm]2
step1312CPLX0-2621Gef dimerPeriplasmic (G)HOKC_ECOLIP0ACG4[HokC]2
step1487CPLX0-7654GlpF glycerol MIP channelIntegral Inner Membrane (B)GLPF_ECOLIP0AER0[GlpF]4
step1196CPLX-169glucitol/sorbitol PTS permeaseIntegral Inner Membrane (B)PTHC_ECOLI
PTHB_ECOLI
PTHA_ECOLI
P56579
P56580
P05706
[SrlA][SrlB][SrlE]
step1752GLUCOSAMINE-6-P-DEAMIN-CPLXglucosamine-6-phosphate deaminaseCytoplasmic (A)NAGB_ECOLIP0A759[NagB]6
step1186CPLX-157glucose PTS permeaseIntegral Inner Membrane (B)PTGCB_ECOLI
PTGA_ECOLI
P69786
P69783
[PtsG]2[Crr]
step1750GLUC1PADENYLTRANS-CPLXglucose-1-phosphate adenylyltransferaseCytoplasmic (A)GLGC_ECOLIP0A6V1[GlgC]4
step1039ABC-13-CPLXglutamate / aspartate ABC transporterIntegral Inner Membrane (B)GLTL_ECOLI
GLTI_ECOLI
GLTJ_ECOLI
GLTK_ECOLI
P0AAG3
P37902
P0AER3
P0AER5
[GltI][GltK][GltJ][GltL]
step1760GLUTDECARBOXA-CPLXglutamate decarboxylase ACytoplasmic (A)DCEA_ECOLIP69908[GadA]6
step1761GLUTDECARBOXB-CPLXglutamate decarboxylase BCytoplasmic (A)DCEB_ECOLIP69910[GadB]6
step1746GDHA-CPLXglutamate dehydrogenaseCytoplasmic (A)DHE4_ECOLIP00370[GdhA]6
step1763GLUTRACE-CPLXglutamate racemaseCytoplasmic (A)MURI_ECOLIP22634[MurI]2
step1754GLUTAMATESYN-CPLXglutamate synthasePeripheral inner membrane protein facing the cytoplasm (F1)GLTB_ECOLI
GLTD_ECOLI
P09831
P09832
[(GltD)(GltB)]4
step1755GLUTAMATESYN-DIMERglutamate synthasePeripheral inner membrane protein facing the cytoplasm (F1)GLTB_ECOLI
GLTD_ECOLI
P09831
P09832
[(GltD)(GltB)]4
step1777GSAAMINOTRANS-CPLXglutamate-1-semialdehyde aminotransferaseCytoplasmic (A)GSA_ECOLIP23893[HemL]2
step1764GLUTSEMIALDEHYDROG-CPLXglutamate-5-semialdehyde dehydrogenaseCytoplasmic (A)PROA_ECOLIP07004[ProA]4
step1522CPLX0-7709glutamate-putrescine ligaseCytoplasmic (A)PUUA_ECOLIP78061[PuuA]12
step1608CPLX0-7887glutamate-pyruvate aminotransferaseCytoplasmic (A)ALAC_ECOLIP77434[AlaC]2
step1609CPLX0-7888glutamate-pyruvate aminotransferaseCytoplasmic (A)ALAA_ECOLIP0A959[AlaA]2
step1513CPLX0-7694glutaminaseCytoplasmic (A)GLSA1_ECOLIP77454[GlsA1]4
step1514CPLX0-7695glutaminaseCytoplasmic (A)GLSA2_ECOLIP0A6W0[GlsA2]2
step2036GLUTAMINA-CPLXglutaminaseCytoplasmic (A)GLSA1_ECOLIP77454[Glsa1]4
step2037GLUTAMINB-CPLXglutaminase BCytoplasmic (A)GLSA2_ECOLIP0A6W0[Glsa2]4
step1038ABC-12-CPLXglutamine ABC transporterIntegral Inner Membrane (B)GLNP_ECOLI
GLNH_ECOLI
GLNQ_ECOLI
P0AEQ6
P0AEQ3
P10346
[GlnQ]2[GlnP]2[GlnH]
step1757GLUTAMINESYN-OLIGOMERglutamine synthetaseCytoplasmic (A)GLNA_ECOLIP0A9C5[GlnA]12
step1369CPLX0-3741glutamyl-tRNA reductaseCytoplasmic (A)HEM1_ECOLIP0A6X1[HemA]2
step1579CPLX0-7817glutaredoxin 4Cytoplasmic (A)GLRX4_ECOLIP0AC69[GrxD]2
step1070ABC-49-CPLXglutathione ABC transporterIntegral Inner Membrane (B)GSIA_ECOLI
GSID_ECOLI
GSIC_ECOLI
GSIB_ECOLI
P75796
P75799
P75798
P75797
[GsiA]2[GsiB][GsiD][GsiC]
step1081ABC-6-CPLXglutathione ABC transporter CydDCIntegral Inner Membrane (B)CYDD_ECOLI
CYDC_ECOLI
P29018
P23886
[CydD]2[CydC]2
step1758GLUTATHIONE-REDUCT-NADPH-CPLXglutathione reductaseCytoplasmic (A)GSHR_ECOLIP06715[Gor]2
step1779GST-CPLXglutathione S-transferaseCytoplasmic (A)GSTA_ECOLIP0A9D2[GstA]2
step1759GLUTATHIONE-SYN-CPLXglutathione synthetaseCytoplasmic (A)GSHB_ECOLIP04425[GshB]4
step1743GAPDH-A-CPLXglyceraldehyde 3-phosphate dehydrogenase-A complexCytoplasmic (A)G3P1_ECOLIP0A9B2[GapA]4
step1112AERGLYC3PDEHYDROG-CPLXglycerol 3-phosphate dehydrogenase, aerobicPeripheral inner membrane protein facing the cytoplasm (F1)GLPD_ECOLIP13035[GlpD]2
step1767GLYCEROL-KIN-CPLXglycerol kinaseCytoplasmic (A)GLPK_ECOLIP0A6F3[GlpK]4
step1060ABC-34-CPLXglycerol-3-phosphate / glycerol-2-phosphate ABCtransporterIntegral Inner Membrane (B)UGPB_ECOLI
UGPA_ECOLI
UGPC_ECOLI
UGPE_ECOLI
P0AG80
P10905
P10907
P10906
[UgpC]2[UgpA][UgpE][UgpB]
step1765GLYC3PDEHYDROGBIOSYN-CPLXglycerol-3-phosphate dehydrogenase, biosyntheticCytoplasmic (A)GPDA_ECOLIP0A6S7[GpsA]2
step1122ANGLYC3PDEHYDROG-CPLXglycerol-3-phosphate-dehydrogenase, anaerobicPeripheral inner membrane protein facing the cytoplasm (F1)GLPC_ECOLI
GLPB_ECOLI
GLPA_ECOLI
P0A996
P13033
P0A9C0
[GlpA][GlpB][GlpC]
step1769GLYCPDIESTER-PERI-CPLXglycerophosphoryl diester phosphodiesterase, periplasmicPeriplasmic (G)GLPQ_ECOLIP09394[GlpQ]2
step1052ABC-26-CPLXglycine betaine / proline ABC transporterIntegral Inner Membrane (B)PROV_ECOLI
PROW_ECOLI
PROX_ECOLI
P14175
P14176
P0AFM2
[ProV]2[ProW]2[ProX]
step1744GCVMULTI-CPLXglycine cleavage systemPeripheral inner membrane protein facing the cytoplasm (F1)GCSH_ECOLI
GCSP_ECOLI
GCST_ECOLI
DLDH_ECOLI
P0A6T9
P33195
P27248
P0A9P0
[(DldH)2][(GcvP)2][GcvH][GcvT]
step1745GCVP-CPLXglycine decarboxylaseCytoplasmic (A)GCSP_ECOLIP33195[GcvP]2
step1768GLYCOPHOSPHORYL-CPLXglycogen phosphorylaseCytoplasmic (A)PHSG_ECOLIP0AC86[GlgP]2
step1437CPLX0-7458glycolate oxidaseCytoplasmic (A)GLCF_ECOLI
GLCD_ECOLI
GLCE_ECOLI
P52074
P0AEP9
P52073
[GlcD][GlcE][GlcF]
step1773GLYS-CPLXglycyl-tRNA synthetaseCytoplasmic (A)SYGB_ECOLI
SYGA_ECOLI
P00961
P00960
[GlyS]2[GlyQ]2
step1772GLYOXI-CPLXglyoxalase ICytoplasmic (A)LGUL_ECOLIP0AC81[GloA]2
step1658CPLX0-861glyoxalase III, Hsp31 molecular chaperoneCytoplasmic (A)HCHA_ECOLIP31658[HchA]2
step1770GLYOCARBOLIG-CPLXglyoxylate carboligaseCytoplasmic (A)GCL_ECOLIP0AEP7[Gcl]2
step1283CPLX0-235glyoxylate reductase / glyoxylate reductase B / 2-ketoaldonate reductaseCytoplasmic (A)GHRB_ECOLIP37666[GhrB]2
step1774GMP-REDUCT-CPLXGMP reductaseCytoplasmic (A)GUAC_ECOLIP60560[GuaC]4
step1775GMP-SYN-CPLXGMP synthetaseCytoplasmic (A)GUAA_ECOLIP04079[GuaA]2
step1391CPLX0-3934GroEL-GroES chaperonin complexCytoplasmic (A)CH10_ECOLI
CH60_ECOLI
P0A6F9
P0A6F5
[GroL]14[GroS]7
step1635CPLX0-7942Grx4-BolA complexN,F1GLRX4_ECOLI
BOLA_ECOLI
P0AC69
P0ABE2
[BolA][GrxD]
step1352CPLX0-3382GspC-O secreton complexProtein complex spanning both membranesGSPK_ECOLI
GSPC_ECOLI
GSPI_ECOLI
GSPH_ECOLI
GSPF_ECOLI
GSPG_ECOLI
GSPL_ECOLI
GSPD_ECOLI
GSPM_ECOLI
GSPE_ECOLI
LEP4_ECOLI
GSPJ_ECOLI
P45762
P45757
P45760
P41443
P41441
P41442
P45763
P45758
P36678
P45759
P25960
P45761
[GspC][GspD][GspE][GspF][GspG][GspH][GspI][GspJ][GspK][GspL][GspM][GspO]
step1727FOLE-CPLXGTP cyclohydrolase ICytoplasmic (A)GCH1_ECOLIP0A6T5[FolE]10
step1780GTP-CYCLOHYDRO-II-CPLXGTP cyclohydrolase IICytoplasmic (A)RIBA_ECOLIP0A7I7[RibA]2
step1360CPLX0-3561GTP hydrolase involved in nickel liganding intohydrogenasesCytoplasmic (A)HYPB_ECOLIP0AAN3[HypB]2
step1454CPLX0-7608GTP-binding protein with a role in modification of tRNAPeripheral inner membrane protein facing the cytoplasm (F1)MNME_ECOLIP25522[MnmE]2
step1889PPPGPPHYDRO-CPLXguanosine-5'-triphosphate, 3'-diphosphatepyrophosphataseIntegral Inner Membrane (B)GPPA_ECOLIP25552[GppA]2
step1781GUANYL-KIN-CPLXguanylate kinaseCytoplasmic (A)KGUA_ECOLIP60546[Gmk]2
step1655CPLX0-801HdeA dimer, inactive form of acid-resistance proteinPeriplasmic (G)HDEA_ECOLIP0AES9[HdeA]2
step1380CPLX0-3921heat shock protein, hemimethylated DNA-binding proteinCytoplasmic (A)HSPQ_ECOLIP0AB20[HspQ]2
step1794HYDROPEROXIDII-CPLXheme d synthase / hydroperoxidaseCytoplasmic (A)DCUP_ECOLI
CATE_ECOLI
P29680
P21179
[KatE]6
step2010N/AHemX homoexamerIntegral Inner Membrane (B)HEMX_ECOLIP09127[HemX]6
step2009N/AHemX homotetramerIntegral Inner Membrane (B)HEMX_ECOLIP09127[HemX]4
step1234CPLX0-1461HF-I, host factor for RNA phage Q β replicationPeripheral inner membrane protein facing the cytoplasm (F1)HFQ_ECOLIP0A6X3[Hfq]6
step1323CPLX0-2982HflB, integral membrane ATP-dependent zincmetallopeptidaseIntegral Inner Membrane (B)FTSH_ECOLI
HFLK_ECOLI
HFLC_ECOLI
P0AAI3
P0ABC7
P0ABC3
[(HflK)(HflC)]6[FtsH]6
step1228CPLX0-1321HflK-HflC complex; regulator of FtsH proteaseIntegral Inner Membrane (B)HFLK_ECOLI
HFLC_ECOLI
P0ABC7
P0ABC3
[HflK][HflC]
step1552CPLX0-7757HipB antitoxin and DNA-binding transcriptional repressorNucleoid (N)HIPB_ECOLIP23873[HipB]2
step1430CPLX0-7425HipB-HipA antitoxin/toxin complex and DNA-binding transcriptional repressorNucleoid (N)HIPA_ECOLI
HIPB_ECOLI
P23874
P23873
[(HipB)2][HipA]2
step1785HISTDEHYD-CPLXhistidinal dehydrogenase / histidinol dehydrogenaseCytoplasmic (A)HISX_ECOLIP06988[HisD]2
step1040ABC-14-CPLXhistidine ABC transporterIntegral Inner Membrane (B)HISM_ECOLI
HISQ_ECOLI
HISP_ECOLI
HISJ_ECOLI
P0AEU3
P52094
P07109
P0AEU0
[HisP]2[HisM][HisQ][HisJ]
step1786HISTPHOSTRANS-CPLXhistidinol-phosphate aminotransferaseCytoplasmic (A)HIS8_ECOLIP06986[HisC]2
step1784HISS-CPLXhistidyl-tRNA synthetaseCytoplasmic (A)SYH_ECOLIP60906[HisS]2
step1788HOLO-ACP-SYNTH-CPLXholo-[acyl-carrier-protein] synthaseCytoplasmic (A)ACPS_ECOLIP24224[AcpS]2
step2130N/AHomodimer of YdgAPeripheral inner membrane protein facing the periplasm (F2)YDGA_ECOLIP77804[YdgA]2
step1789HOMOSERKIN-CPLXhomoserine kinaseCytoplasmic (A)KHSE_ECOLIP00547[ThrB]2
step1790HOMSUCTRAN-CPLXhomoserine O-succinyltransferaseCytoplasmic (A)META_ECOLIP07623[MetA]2
step1220CPLX0-1161HslU hexamerCytoplasmic (A)HSLU_ECOLIP0A6H5[HslU]6
step1221CPLX0-1162HslV hexamerCytoplasmic (A)HSLV_ECOLIP0A7B8[HslV]6
step1222CPLX0-1163HslVU proteaseCytoplasmic (A)HSLV_ECOLI
HSLU_ECOLI
P0A7B8
P0A6H5
[(HslU)6]2[(HslV)6]2
step1264CPLX0-2021HU DNA-binding transcriptional dual regulatorN,F1DBHA_ECOLI
DBHB_ECOLI
P0ACF0
P0ACF4
[HupA][HupB]
step1732FORMHYDROGI-CPLXhydrogenase 1Integral Inner Membrane (B)CYBH_ECOLI
MBHL_ECOLI
MBHS_ECOLI
P0AAM1
P0ACD8
P69739
[HyaA][HyaB][HyaC]
step1731FORMHYDROG2-CPLXhydrogenase 2Integral Inner Membrane (B)HYBB_ECOLI
MBHT_ECOLI
HYBA_ECOLI
MBHM_ECOLI
P37180
P69741
P0AAJ8
P0ACE0
[HybA][HybB][HybO][HybC]
step1792HYDROG3-CPLXhydrogenase 3Integral Inner Membrane (B)HYCB_ECOLI
HYCD_ECOLI
HYCC_ECOLI
HYCE_ECOLI
HYCF_ECOLI
HYCG_ECOLI
P0AAK1
P16430
P16429
P16431
P16432
P16433
[HycD][HycC][HycF][HycG][HycB][HycE]
step1302CPLX0-250hydrogenase 4Integral Inner Membrane (B)HYFB_ECOLI
HYFC_ECOLI
HYFH_ECOLI
HYFE_ECOLI
HYFF_ECOLI
HYFD_ECOLI
HYFG_ECOLI
HYFI_ECOLI
HYFA_ECOLI
P23482
P77858
P77423
P0AEW1
P77437
P77416
P77329
P77668
P23481
[HyfG][HyfI][HyfA][HyfB][HyfC][HyfD][HyfE][HyfF][HyfH]
step1793HYDROPEROXIDI-CPLXhydroperoxidase ICytoplasmic (A)KATG_ECOLIP13029[KatG]4
step1416CPLX0-4Hydroxylated aromatic carboxylic acid efflux transporterIntegral Inner Membrane (B)AAEA_ECOLI
AAEB_ECOLI
P46482
P46481
[AaeA][AaeB]
step1787HMP-P-KIN-CPLXhydroxymethylpyrimidine kinase /phosphohydroxymethylpyrimidine kinaseCytoplasmic (A)THID_ECOLI
HMP_ECOLI
P76422
P24232
[ThiD]4
step1396CPLX0-3941hydroxyphenylacetyl-CoA thioesteraseCytoplasmic (A)PAAI_ECOLIP76084[PaaI]4
step1198CPLX-171hydroxypyruvate isomeraseCytoplasmic (A)HYI_ECOLIP30147[Hyi]2
step1375CPLX0-3821HypA-HypB heterodimerCytoplasmic (A)HYPA_ECOLI
HYPB_ECOLI
P0A700
P0AAN3
[HypA][HypB]
step2038CPLX0-7986HypCD complex involved in hydrogenase maturationCytoplasmic (A)HYPD_ECOLI
HYPC_ECOLI
P24192
P0AAM3
[HypD][HypC]
step1506CPLX0-7685hypoxanthine phosphoribosyltransferaseCytoplasmic (A)HPRT_ECOLIP0A9M2[Hpt]4
step2039CPLX0-7970HypT-[Met]reducedNucleoid (N)YJIE_ECOLIP39376[(HypT)2]
step1861PC00027IHF DNA-binding transcriptional dual regulatorN,F1IHFA_ECOLI
IHFB_ECOLI
P0A6X7
P0A6Y1
[IhfA][IhfB]
step1756GLUTAMIDOTRANS-CPLXimidazole glycerol phosphate synthaseCytoplasmic (A)HIS6_ECOLI
HIS5_ECOLI
P60664
P60595
[HisH][HisF]
step1795IMIDHISTID-CPLXimidazoleglycerol-phosphate dehydratase / histidinol-phosphataseCytoplasmic (A)HIS7_ECOLIP06987[HisB]2
step1796IMP-DEHYDROG-CPLXIMP dehydrogenaseCytoplasmic (A)IMDH_ECOLIP0ADG7[GuaB]4
step1662CPLX0-921inhibitor of vertebrate C-type lysozymePeriplasmic (G)IVY_ECOLIP0AD59[Ivy]2
step1296CPLX0-243inorganic pyrophosphataseCytoplasmic (A)IPYR_ECOLIP0A7A9[Ppa]6
step1343CPLX0-322inosine-guanosine kinaseCytoplasmic (A)INGK_ECOLIP0AEW6[Gsk]2
step1037ABC-11-CPLXiron (III) hydroxamate ABC transporterIntegral Inner Membrane (B)FHUC_ECOLI
FHUB_ECOLI
FHUD_ECOLI
P07821
P06972
P07822
[FhuC]2[FhuB]2[FhuD]
step1613CPLX0-7908iron-sulfur cluster assembly proteinCytoplasmic (A)ISCA_ECOLIP0AAC8[IscA]4
step1503CPLX0-7682iron-sulfur cluster scaffold proteinCytoplasmic (A)NFUA_ECOLIP63020[NfuA]2
step2040CPLX0-7417IS2 insertion element repressor InsACytoplasmic (A)INSC1_ECOLIP0CF40[InsC-1]2
step1327CPLX0-3021isoaspartyl dipeptidaseCytoplasmic (A)IADA_ECOLIP39377[IadA]8
step1313CPLX0-263isoaspartyl dipeptidase / asparaginase IIICytoplasmic (A)IAAA_ECOLIP37595[IaaA]2[IaaA]2
step1819MENF-CPLXisochorismate synthase 2Cytoplasmic (A)MENF_ECOLIP38051[MenF]2
step1798ISOCITHASE-CPLXisocitrate dehydrogenaseCytoplasmic (A)IDH_ECOLIP08200[Icd]2
step1279CPLX0-230isocitrate dehydrogenase phosphatase / isocitratedehydrogenase kinaseCytoplasmic (A)ACEK_ECOLIP11071[AceK]2
step1797ISOCIT-LYASEisocitrate lyaseCytoplasmic (A)ACEA_ECOLIP0A9G6[AceA]4
step10283-ISOPROPYLMALISOM-CPLXisopropylmalate isomeraseCytoplasmic (A)LEUD_ECOLI
LEUC_ECOLI
P30126
P0A6A6
[LeuC][LeuD]
step1510CPLX0-7691isovaleryl-CoA dehydrogenase and DNA-binding transcriptional repressorNucleoid (N)AIDB_ECOLIP33224[AidB]4
step1155ATPASE-1-CPLXK+ transporting ATPaseIntegral Inner Membrane (B)ATKA_ECOLI
KDPF_ECOLI
ATKC_ECOLI
ATKB_ECOLI
P03959
P36937
P03961
P03960
[KdpF][KdpA][KdpB][KdpC]
step1719FABB-CPLXKASICytoplasmic (A)FABB_ECOLIP0A953[FabB]2
step10303-OXOACYL-ACP-SYNTHII-CPLXKASIICytoplasmic (A)FABF_ECOLIP0AAI5[FabF]2
step1305CPLX0-252KASIIICytoplasmic (A)FABH_ECOLIP0A6R0[FabH]2
step1499CPLX0-7674Kch potassium VIC channelIntegral Inner Membrane (B)KCH_ECOLIP31069[Kch]4
step1801KDPD-CPLXKdpD sensory histidine kinaseIntegral Inner Membrane (B)KDPD_ECOLIP21865[KdpD]2
step1564CPLX0-7795KdpE-Phosphorylated DNA-binding transcriptional activatorNucleoid (N)KDPE_ECOLIP21866[KdpE]2
step1580CPLX0-7819KefC potassium CPA2 transporterIntegral Inner Membrane (B)KEFC_ECOLIP03819[KefC]2
step1766GLYCDEH-CPLXL-1,2-propanediol dehydrogenase / glycerol dehydrogenaseCytoplasmic (A)GLDA_ECOLIP0A9S5[GldA]8
step1804LACTALDREDUCT-CPLXL-1,2-propanediol oxidoreductaseCytoplasmic (A)FUCO_ECOLIP0A9S1[FucO]2
step1651CPLX0-7962L-amino acid N-acyltransferaseCytoplasmic (A)YNCA_ECOLIP76112[YncA]2
step1130ARABISOM-CPLXL-arabinose isomeraseCytoplasmic (A)ARAA_ECOLIP08202[AraA]6
step1597CPLX0-7848L-ascorbate 6-phosphate lactonaseCytoplasmic (A)ULAG_ECOLIP39300[UlaG]6
step1706EIISGAL-ascorbate PTS permeaseIntegral Inner Membrane (B)ULAA_ECOLI
ULAB_ECOLI
ULAC_ECOLI
P39301
P69822
P69820
[UlaC][UlaB][UlaA]2
step1612CPLX0-7906L-carnitine/γ-butyrobetaine antiportIntegral Inner Membrane (B)CAIT_ECOLIP31553[CaiT]3
step1670CYSTATHIONINE-BETA-LYASE-CPLXL-cysteine desulfhydrase / cystathionine-β-lyaseCytoplasmic (A)METC_ECOLIP06721[MetC]4
step1971TRYPTOPHAN-CPLXL-cysteine desulfhydrase / tryptophanaseCytoplasmic (A)TNAA_ECOLIP0A853[TnaA]4
step1472CPLX0-7631L-fucose isomeraseCytoplasmic (A)FUCI_ECOLIP69922[FucI]6
step1480CPLX0-7645L-fucose mutarotaseCytoplasmic (A)FUCM_ECOLIP0AEN8[FucU]6
step1474CPLX0-7633L-fuculose-phosphate aldolaseCytoplasmic (A)FUCA_ECOLIP0AB87[FucA]4
step1803L-GLN-FRUCT-6-P-AMINOTRANS-CPLXL-glutamine:D-fructose-6-phosphate aminotransferaseCytoplasmic (A)GLMS_ECOLIP17169[GlmS]2
step1823METNIQ-METHIONINE-ABC-CPLXL-methionine / D-methionine ABC transporterB&EMETQ_ECOLI
METN_ECOLI
METI_ECOLI
P28635
P30750
P31547
[MetN]2[MetI][MetQ]
step1532CPLX0-7722L-rhamnonate dehydrataseCytoplasmic (A)RHMD_ECOLIP77215[rhmD]8
step1485CPLX0-7652L-rhamnose isomeraseCytoplasmic (A)RHAA_ECOLIP32170[RhaA]4
step1484CPLX0-7649L-rhamnose mutarotaseCytoplasmic (A)RHAM_ECOLIP32156[RhaM]2
step1914RIBULOKIN-CPLXL-ribulokinaseCytoplasmic (A)ARAB_ECOLIP08204[AraB]2
step1915RIBULPEPIM-CPLXL-ribulose 5-phosphate 4-epimeraseCytoplasmic (A)ARAD_ECOLIP08203[AraD]4
step1463CPLX0-7622L-serine deaminase IIIIntegral Inner Membrane (B)TDCG_ECOLIP42630[TdcG]2
step1807LTARTDEHYDRA-CPLXL-tartrate dehydrataseCytoplasmic (A)TTDB_ECOLI
TTDA_ECOLI
P0AC35
P05847
[(TtdA)2][(TtdB)2]
step1973TTDA-CPLXL-tartrate dehydratase, α subunitCytoplasmic (A)TTDA_ECOLIP05847[TtdA]2
step1974TTDB-CPLXL-tartrate dehydratase, β subunitCytoplasmic (A)TTDB_ECOLIP0AC35[TtdB]2
step1812LYXK-CPLXL-xylulose kinaseCytoplasmic (A)LYXK_ECOLIP37677[Lyx]2
step1934N/ALactose operon repressorCytoplasmic (A)LACI_ECOLIP03023[LacI]4
step1057ABC-304-CPLXleucine ABC transporterIntegral Inner Membrane (B)LIVK_ECOLI
LIVM_ECOLI
LIVG_ECOLI
LIVH_ECOLI
LIVF_ECOLI
P04816
P22729
P0A9S7
P0AEX7
P22731
[LivK][LivM][LivH][LivG][LivF]
step1860PC00010LexA DNA-binding transcriptional repressorNucleoid (N)LEXA_ECOLIP0A7C2[LexA]2
step1423CPLX0-7415lipid A disaccharide synthasePeripheral inner membrane protein facing the cytoplasm (F1)LPXB_ECOLIP10441[LpxB]2
step1547CPLX0-7747lipid hydroperoxide peroxidaseCytoplasmic (A)TPX_ECOLIP0A862[Tpx]2
step1704E3-CPLXlipoamide dehydrogenasePeripheral inner membrane protein facing the cytoplasm (F1)DLDH_ECOLIP0A9P0[DldH]2
step1581CPLX0-782lipoate synthaseCytoplasmic (A)LIPA_ECOLIP60716[LipA]2
step1518CPLX0-7704lipopolysaccharide ABC transporterIntegral Inner Membrane (B)MSBA_ECOLIP60752[MsbA]2
step2041CPLX0-7992lipopolysaccharide transport systemProtein complex spanning both membranesLPTE_ECOLI
LPTG_ECOLI
LPTA_ECOLI
LPTC_ECOLI
LPTF_ECOLI
LPTD_ECOLI
LPTB_ECOLI
P0ADC1
P0ADC6
P0ADV1
P0ADV9
P0AF98
P31554
P0A9V1
[(LptD)(LptE)][(LptG)(LptB)2(LptF)][LptC][LptA]
step1084ABC-62-CPLXLolCDE ABC lipoprotein transporterIntegral Inner Membrane (B)LOLD_ECOLI
LOLE_ECOLI
LOLC_ECOLI
P75957
P75958
P0ADC3
[LolE][LolD]2[LolC]
step1654CPLX0-8longitudinal peptidoglycan synthesis/chromosome segregation-directing complexIntegral Inner Membrane (B)MREB_ECOLI
MRED_ECOLI
MREC_ECOLI
P0A9X4
P0ABH4
P16926
[MreB][MreC][MreD]
step1806LTAA-CPLXlow-specificity L-threonine aldolaseCytoplasmic (A)LTAE_ECOLIP75823[LtaE]4
step1074ABC-53-CPLXLptABCFG ABC transporterIntegral Inner Membrane (B)LPTF_ECOLI
LPTC_ECOLI
LPTB_ECOLI
LPTA_ECOLI
LPTG_ECOLI
P0AF98
P0ADV9
P0A9V1
P0ADV1
P0ADC6
[LptG][LptF][LptA][LptB]2[LptC]
step2016N/ALptBFGC subcomplexIntegral Inner Membrane (B)LPTF_ECOLI
LPTC_ECOLI
LPTB_ECOLI
LPTG_ECOLI
P0AF98
P0ADV9
P0A9V1
P0ADC6
[LptG][LptF][LptB]2[LptC]
step2042CPLX0-8043LsrR DNA-binding transcriptional repressorNucleoid (N)LSRR_ECOLIP76141[LsrR]4
step1056ABC-3-CPLXlysine / arginine / ornithine ABC transporterIntegral Inner Membrane (B)HISM_ECOLI
HISQ_ECOLI
ARGT_ECOLI
HISP_ECOLI
P0AEU3
P52094
P09551
P07109
[HisQ][HisP]2[HisM][ArgT]
step1809LYSDECARBOX-CPLXlysine decarboxylaseCytoplasmic (A)LDCI_ECOLIP0A9H3[CadA]10
step1805LDC2-CPLXlysine decarboxylase 2Cytoplasmic (A)DCLZ_ECOLIP52095[LdcC]10
step2125N/Alysine-dependent acid resistance system(LDAR)Integral Inner Membrane (B)CADB_ECOLIP0AAE8[CadB]2[LdcI]10
step1810LYSS-CPLXlysyl-tRNA synthetase, constitutiveCytoplasmic (A)SYK1_ECOLIP0A8N3[LysS]2
step1961TRANS-200-CPLXMacAB-TolC macrolide efflux transport systemProtein complex spanning both membranesTOLC_ECOLI
MACB_ECOLI
MACA_ECOLI
P02930
P75831
P75830
[(TolC)3][MacB]2[MacA]
step1561CPLX0-7789macrodomain Ter proteinCytoplasmic (A)MATP_ECOLIP0A8N0[MatP]2
step1813MALATE-DEHASEmalate dehydrogenaseCytoplasmic (A)MDH_ECOLIP61889[Mdh]2
step1816MALIC-NADP-CPLXmalate dehydrogenaseCytoplasmic (A)MAO2_ECOLIP76558[MaeB]6
step1815MALIC-NAD-CPLXmalate dehydrogenase, NAD-requiringCytoplasmic (A)MAO1_ECOLIP26616[MaeA]4
step1824MONOMER0-1761MalT-MalKPeripheral inner membrane protein facing the cytoplasm (F1)MALK_ECOLI
MALT_ECOLI
P68187
P06993
[MalT][MalK]
step1814MALDEXPHOSPHORYL-CPLXmaltodextrin phosphorylaseCytoplasmic (A)PHSM_ECOLIP00490[MalP]2
step1042ABC-16-CPLXmaltose ABC transporterIntegral Inner Membrane (B)MALE_ECOLI
MALG_ECOLI
MALF_ECOLI
MALK_ECOLI
P0AEX9
P68183
P02916
P68187
[MalK]2[MalF][MalG][MalE]
step1817MALTACETYLTRAN-CPLXmaltose acetyltransferaseCytoplasmic (A)MAA_ECOLIP77791[Maa]2
step1191CPLX-164maltose/glucose PTS permeaseIntegral Inner Membrane (B)PTOCB_ECOLI
PTGA_ECOLI
P19642
P69783
[MalX]2[Crr]
step1193CPLX-166mannitol PTS permeaseIntegral Inner Membrane (B)PTM3C_ECOLIP00550[MtlA]2
step1185CPLX-156mannitol PTS permease - crypticIntegral Inner Membrane (B)PTMCB_ECOLI
PTMA_ECOLI
P69826
P69824
[CmtB][CmtA]2
step1504CPLX0-7683mannose isomeraseCytoplasmic (A)YIHS_ECOLIP32140[YihS]6
step1192CPLX-165mannose PTS permeaseIntegral Inner Membrane (B)PTND_ECOLI
PTNC_ECOLI
PTNAB_ECOLI
P69805
P69801
P69797
[ManZ]2[ManY][ManX]2
step1621CPLX0-7921mannose PTS permease - ManX subunitPeripheral inner membrane protein facing the cytoplasm (F1)PTNAB_ECOLIP69797[ManX]2
step1523CPLX0-7710MarR DNA-binding transcriptional repressorNucleoid (N)MARR_ECOLIP27245[MarR]2
step1657CPLX0-841MazE antitoxin of the MazF-MazE toxin-antitoxin systemNucleoid (N)MAZE_ECOLIP0AE72[MazE]2
step1225CPLX0-1242MazE-MazF antitoxin/toxin complex and DNA-binding transcriptional repressorNucleoid (N)MAZF_ECOLI
MAZE_ECOLI
P0AE70
P0AE72
[(MazF)2]2[(MazE)2]
step1224CPLX0-1241MazF toxin of the MazF-MazE toxin-antitoxin system that exhibits ribonuclease activityCytoplasmic (A)MAZF_ECOLIP0AE70[MazF]2
step1972TSR-CPLXMCP-IIntegral Inner Membrane (B)CHEA_ECOLI
MCP1_ECOLI
CHEW_ECOLI
P07363
P02942
P0A964
[CheW]2[(CheA)2][Tsr]2
step1948TAR-CPLXMCP-IIIntegral Inner Membrane (B)CHEA_ECOLI
MCP2_ECOLI
CHEW_ECOLI
P07363
P07017
P0A964
[(CheA)2][CheW]2[Tar]2
step1968TRG-CPLXMCP-IIIIntegral Inner Membrane (B)CHEA_ECOLI
MCP3_ECOLI
CHEW_ECOLI
P07363
P05704
P0A964
[(CheA)2][CheW]2[Trg]2
step1947TAP-CPLXMCP-IVIntegral Inner Membrane (B)MCP4_ECOLI
CHEA_ECOLI
CHEW_ECOLI
P07018
P07363
P0A964
[(CheA)2][CheW]2[Tap]2
step1315CPLX0-2661McrBC restriction endonucleaseCytoplasmic (A)MCRC_ECOLI
MCRB_ECOLI
P15006
P15005
[McrB][McrC]
step2118N/AMdh inside 24-meric DegP cagePeriplasmic (G)MDH_ECOLI
DEGP_ECOLI
P61889
P0C0V0
[DegP]24[Mdh]
step1963TRANS-CPLX-202MdtABC-TolC multidrug efflux transport systemProtein complex spanning both membranesTOLC_ECOLI
MDTB_ECOLI
MDTC_ECOLI
MDTA_ECOLI
P02930
P76398
P76399
P76397
[(TolC)3][MdtC][MdtB][MdtA]
step1965TRANS-CPLX-204MdtEF-TolC multidrug efflux transport systemProtein complex spanning both membranesTOLC_ECOLI
MDTE_ECOLI
MDTF_ECOLI
P02930
P37636
P37637
[(TolC)3][MdtE]3[MdtF]3
step1987YDGEF-CPLXMdtJI spermidine SMR transporterIntegral Inner Membrane (B)MDTI_ECOLI
MDTJ_ECOLI
P69210
P69212
[MdtJ][MdtI]
step1468CPLX0-7627mechanosensitive channel MscLIntegral Inner Membrane (B)MSCL_ECOLIP0A742[MscL]5
step1467CPLX0-7626mechanosensitive channel MscSIntegral Inner Membrane (B)MSCS_ECOLIP0C0S1[MscS]7
step2043CPLX0-7985mechanosensitive channel of miniconductanceIntegral Inner Membrane (B)MSCM_ECOLIP39285[MscM]7
step2044CPLX0-7981mechanosensitive channel of miniconductance YbdGIntegral Inner Membrane (B)YBDG_ECOLIP0AAT4[YbdG]7
step2045CPLX0-7983mechanosensitive channel YbiOIntegral Inner Membrane (B)YBIO_ECOLIP75783[YbiO]7
step2046CPLX0-7982mechanosensitive channel YnaIIntegral Inner Membrane (B)YNAI_ECOLIP0AEB5[YnaI]7
step2134N/AMembranre complex of Ycis (LapA) with RodZIntegral Inner Membrane (B)LAPA_ECOLI
RODZ_ECOLI
P0ACV4
P27434
[LapA][RodZ]
step2135N/AMembranre complex of Ycis (LapA) with YhcBIntegral Inner Membrane (B)LAPA_ECOLI
YHCB_ECOLI
P0ACV4
P0ADW3
[LapA][YhcB]
step1922S-ADENMETSYN-CPLXmethionine adenosyltransferaseCytoplasmic (A)METK_ECOLIP0A817[MetK]4
step1820METG-CPLXmethionyl-tRNA synthetaseCytoplasmic (A)SYM_ECOLIP00959[MetG]2
step2047CPLX0-8104methyl accepting chemotaxis protein - dipeptide sensing, subunit of chemotaxis signaling complex - dipeptide sensingIntegral Inner Membrane (B)MCP4_ECOLIP07018[Tap]2
step2048CPLX0-8105methyl accepting chemotaxis protein - ribose/galactose/glucose sensing, subunit of chemotaxis signaling complex - ribose/galactose/glucose sensingIntegral Inner Membrane (B)MCP3_ECOLIP05704[Trg]2
step2049CPLX0-8103methyl accepting chemotaxis protein - serine sensing, subunit of chemotaxis signaling complex - serine sensingIntegral Inner Membrane (B)MCP1_ECOLIP02942[Tsr]2
step2050CPLX0-8102methyl accepting chemotaxis protein Tar, subunit of chemotaxis signaling complex - aspartate sensingIntegral Inner Membrane (B)MCP2_ECOLIP07017[Tar]2
step1304CPLX0-251methylcitrate synthaseCytoplasmic (A)PRPC_ECOLIP31660[PrpC]2
step1821METHGLYSYN-CPLXmethylglyoxal synthaseCytoplasmic (A)MGSA_ECOLIP0A731[MgsA]6
step1308CPLX0-254methylmalonyl-CoA decarboxylaseCytoplasmic (A)SCPB_ECOLIP52045[ScpB]6
step1544CPLX0-7741methylmalonyl-CoA mutaseCytoplasmic (A)SCPA_ECOLIP27253[ScpA]2
step1647CPLX0-7958methylphosphonate degradation complexPeripheral inner membrane protein facing the cytoplasm (F1)PHNL_ECOLI
PHNG_ECOLI
PHNH_ECOLI
PHNI_ECOLI
P16679
P16685
P16686
P16687
[PhnL][PhnH][PhnG][PhnI]
step2051CPLX0-8027MetJ-adenineNucleoid (N)METJ_ECOLIP0A8U6[adenine][MetJ]
step2052CPLX0-8026MetJ-MTANucleoid (N)METJ_ECOLIP0A8U6[S-methyl-5'-thioadenosine][MetJ]
step1565CPLX0-7796MetJ-S-adenosylmethionine DNA-binding transcriptional repressorNucleoid (N)METJ_ECOLIP0A8U6[(MetJ)
step1554CPLX0-7759MetR DNA-binding transcriptional dual regulatorNucleoid (N)METR_ECOLIP0A9F9[MetR]2
step2121N/AMg2+/Ni2+/Co2+ transporterIntegral Inner Membrane (B)CORA_ECOLIP0ABI4[CorA]4
step1868PC00103MngR DNA-binding transcriptional repressorNucleoid (N)MNGR_ECOLIP13669[MngR]2
step1498CPLX0-7672MntR-Mn2+ DNA-binding transcriptional dual regulatorNucleoid (N)MNTR_ECOLIP0A9F1[(MntR)(Mn2+)]2
step1209CPLX-8331MoaC hexamerCytoplasmic (A)MOAC_ECOLIP0A738[(MoaC)2]3
step1210CPLX-8332MoaC hexamerCytoplasmic (A)MOAC_ECOLIP0A738[(MoaC)2]3
step1309CPLX0-2541ModE transcriptional dual regulatorNucleoid (N)MODE_ECOLIP0A9G8[ModE]2
step1314CPLX0-2641molecular chaperone, HSP90 familyPeripheral inner membrane protein facing the cytoplasm (F1)HTPG_ECOLIP0A6Z3[HtpG]2
step1044ABC-19-CPLXmolybdate ABC transporterIntegral Inner Membrane (B)MODC_ECOLI
MODA_ECOLI
MODB_ECOLI
P09833
P37329
P0AF01
[ModC]2[ModB]2[ModA]
step1832NAPAB-CPLXmolybdoprotein complexPeriplasmic (G)NAPB_ECOLI
NAPA_ECOLI
P0ABL3
P33937
[NapA][NapB]
step1306CPLX0-2521molybdopterin biosynthesis protein BCytoplasmic (A)MOAB_ECOLIP0AEZ9[MoaB]6
step2053CPLX0-8045molybdopterin molybdenumtransferaseCytoplasmic (A)MOEA_ECOLIP12281[MoeA]2
step1303CPLX0-2502molybdopterin synthaseCytoplasmic (A)MOAE_ECOLI
MOAD_ECOLI
P30749
P30748
[MoaD]2[MoaE]2
step2054CPLX0-8044molybdopterin-guanine dinucleotide biosynthesis adaptor proteinNucleoid (N)MOBB_ECOLIP32125[MobB]2
step2055CPLX0-7979monoacetylchitobiose-6-phosphate hydrolaseCytoplasmic (A)CHBF_ECOLIP17411[ChbF]4
step1424CPLX0-7418MprA DNA-binding transcriptional repressorNucleoid (N)MPRA_ECOLIP0ACR9[MprA]2
step1583CPLX0-7822MqsA-MqsR antitoxin/toxin complex and DNA-binding transcriptional repressorNucleoid (N)MQSA_ECOLI
MQSR_ECOLI
Q46864
Q46865
[MqsA]2[MqsR]4
step1311CPLX0-2561MukBEF complexN,F1MUKE_ECOLI
MUKB_ECOLI
MUKF_ECOLI
P22524
P22523
P60293
[(MukB)2][(MukE)4([MukF]2)]
step1516CPLX0-7697MukEF complexN,F1MUKE_ECOLI
MUKF_ECOLI
P22524
P60293
[MukE]4[(MukF)2]
step1517CPLX0-7698MukF dimerN,F1MUKF_ECOLIP60293[MukF]2
step1652CPLX0-7963multidrug efflux transporter EmrEIntegral Inner Membrane (B)EMRE_ECOLIP23895[EmrE]2
step1802KDPGALDOL-4OH2OXOGLUTARALDOL-CPLXmultifunctional 2-keto-3-deoxygluconate 6-phosphatealdolase and 2-keto-4-hydroxyglutarate aldolase and oxaloacetate decarboxylaseCytoplasmic (A)ALKH_ECOLIP0A955[Eda]3
step1471CPLX0-7630multifunctional acyl-CoA thioesterase I and protease Iand lysophospholipase L1Periplasmic (G)TESA_ECOLIP0ADA1[TesA]4
step1618CPLX0-7914multifunctional nucleaseCytoplasmic (A)YGBT_ECOLIQ46896[YgbT]2
step1341CPLX0-3201murein DD-endopeptidase, penicillin-insensitivePeriplasmic (G)MEPA_ECOLIP0C0T5[MepA]2
step1413CPLX0-3970murein tripeptide ABC transporter OppBCDFMppAIntegral Inner Membrane (B)OPPF_ECOLI
OPPD_ECOLI
OPPB_ECOLI
MPPA_ECOLI
OPPC_ECOLI
P77737
P76027
P0AFH2
P77348
P0AFH6
[OppB][OppC][OppD][OppF][MppA]
step2056CPLX0-7989murein tripeptide amidase ACytoplasmic (A)MPAA_ECOLIP0ACV6[MpaA]2
step1992N/Amurein-synthesizing holoenzymeProtein complex spanning both membranesPBPA_ECOLI
MIPA_ECOLI
MLTA_ECOLI
P02918
P0A908
P0A935
[PbpA][MipA][MltA]
step1546CPLX0-7745MurR DNA-binding transcriptional dual regulatorNucleoid (N)MURR_ECOLIP77245[MurR]4
step1825MUTHLS-CPLXMutHLS complex, methyl-directed mismatch repairCytoplasmic (A)MUTH_ECOLI
MUTL_ECOLI
MUTS_ECOLI
P06722
P23367
P23909
[MutL][MutS][MutH]
step1457CPLX0-7610N-acetyl-D-galactosamine PTS transporterIntegral Inner Membrane (B)PTPC2_ECOLI
PTPB2_ECOLI
P42905
P42904
[AgaV][AgaW]
step1194CPLX-167N-acetylglucosamine PTS permeaseIntegral Inner Membrane (B)PTW3C_ECOLIP09323[NagE]2
step1830NAG6PDEACET-CPLXN-acetylglucosamine-6-phosphate deacetylaseCytoplasmic (A)NAGA_ECOLIP0AF18[NagA]4
step1826N-ACETYLTRANSFER-CPLXN-acetylglutamate synthaseCytoplasmic (A)ARGA_ECOLIP0A6C5[ArgA]6
step1540CPLX0-7732N-acetylmuramic acid 6-phosphate etheraseCytoplasmic (A)MURQ_ECOLIP76535[MurQ]2
step1421CPLX0-7N-acetylmuramic acid PTS permeaseIntegral Inner Membrane (B)PTYBC_ECOLI
PTGA_ECOLI
P77272
P69783
[MurP][Crr]
step1101ACNEULY-CPLXN-acetylneuraminate lyaseCytoplasmic (A)NANA_ECOLIP0A6L4[NanA]4
step1490CPLX0-7658N-acetylneuraminate mutarotasePeriplasmic (G)NANM_ECOLIP39371[NanM]2
step1284CPLX0-236N-hydroxyarylamine O-acetyltransferaseCytoplasmic (A)NHOA_ECOLIP77567[NhoA]2
step1339CPLX0-3161N-succinyl-L-diaminopimelate desuccinylaseCytoplasmic (A)DAPE_ECOLIP0AED7[DapE]4
step1100ACETYLORNTRANSAM-CPLXN-succinyldiaminopimelate-aminotransferase /acetylornithine transaminaseCytoplasmic (A)ARGD_ECOLIP18335[ArgD]2
step1896PURE-CPLXN5-carboxyaminoimidazole ribonucleotide mutaseCytoplasmic (A)PURE_ECOLIP0AG18[PurE]8
step1897PURK-CPLXN5-carboxyaminoimidazole ribonucleotide synthetaseCytoplasmic (A)PURK_ECOLIP09029[PurK]2
step1420CPLX0-682NAD kinasePeripheral inner membrane protein facing the cytoplasm (F1)PPNK_ECOLIP0A7B3[PpnK]6
step1827NAD-SYNTH-CPLXNAD synthetase, NH3-dependentCytoplasmic (A)NADE_ECOLIP18843[NadE]2
step1425CPLX0-7419NAD(P)H:quinone oxidoreductaseCytoplasmic (A)WRBA_ECOLIP0A8G6[(WrbA)2]2
step1473CPLX0-7632NAD(P)H:quinone oxidoreductaseCytoplasmic (A)WRBA_ECOLIP0A8G6[(WrbA)2]2
step1508CPLX0-7687NAD+-dependent succinate semialdehyde dehydrogenaseCytoplasmic (A)SAD_ECOLIP76149[Sad]2
step1560CPLX0-7788NAD-dependent dihydropyrimidine dehydrogenaseCytoplasmic (A)PREA_ECOLI
PRET_ECOLI
P25889
P76440
[PreT]2[PreA]2
step1350CPLX0-3361NADH dehydrogenase I soluble NADH dehydrogenase fragment Peripheral inner membrane protein facing the cytoplasm (F1)NUOG_ECOLI
NUOF_ECOLI
NUOE_ECOLI
P33602
P31979
P0AFD1
[(NuoE)(NuoF)(NuoG)]
step2058CPLX0-7974NADH pyrophosphataseCytoplasmic (A)NUDC_ECOLIP32664[NudC]2
step1512CPLX0-7693NADH:quinone reductase, FMN dependent / NADH-azoreductaseCytoplasmic (A)AZOR_ECOLIP41407[AzoR]2
step1828NADH-DHI-CPLXNADH:ubiquinone oxidoreductase IIntegral Inner Membrane (B)NUOL_ECOLI
NUOK_ECOLI
NUOCD_ECOLI
NUOJ_ECOLI
NUOB_ECOLI
NUOI_ECOLI
NUOA_ECOLI
NUOG_ECOLI
NUOH_ECOLI
NUOF_ECOLI
NUOM_ECOLI
NUOE_ECOLI
NUON_ECOLI
P33607
P0AFE4
P33599
P0AFE0
P0AFC7
P0AFD6
P0AFC3
P33602
P0AFD4
P31979
P0AFE8
P0AFD1
P0AFF0
[NuoA][NuoH][NuoJ][NuoK][NuoL][NuoM][NuoN][(NuoE)(NuoF)(NuoG)][(NuoB)(NuoC)(NuoI)]
step1275CPLX0-224NADP(H)-dependent FMN reductaseCytoplasmic (A)SSUE_ECOLIP80644[SsuE]2
step1495CPLX0-7667NADP-dependent dehydrogenaseCytoplasmic (A)YQHD_ECOLIQ46856[YqhD]2
step1297CPLX0-244NADPH nitroreductaseCytoplasmic (A)NFSA_ECOLIP17117[NfsA]2
step1307CPLX0-253NADPH quinone reductaseCytoplasmic (A)MDAB_ECOLIP0AEY5[MdaB]2
step1624CPLX0-7927NADPH-dependent curcumin/dihydrocurcumin reductaseCytoplasmic (A)CURA_ECOLIP76113[CurA]2
step2059CPLX0-7975NadR DNA-binding transcriptional repressor and NMN adenylyltransferaseN,F1NADR_ECOLIP27278[NadR]4
step1345CPLX0-3241NapGH, alternative quinol dehydrogenaseIntegral Inner Membrane (B)NAPH_ECOLI
NAPG_ECOLI
P33934
P0AAL3
[NapG][NapH]
step1346CPLX0-3261NarGH catalytic dimer of nitrate reductase APeripheral inner membrane protein facing the cytoplasm (F1)NARG_ECOLI
NARH_ECOLI
P09152
P11349
[NarG][NarH]
step1833NARQ-CPLXNarQ sensory histidine kinaseIntegral Inner Membrane (B)NARQ_ECOLIP27896[NarQ]2
step1834NARX-CPLXNarX sensory histidine kinaseIntegral Inner Membrane (B)NARX_ECOLIP0AFA2[NarX]2
step1470CPLX0-7629NhaA sodium/proton transporterIntegral Inner Membrane (B)NHAA_ECOLIP13738[NhaA]2
step1046ABC-20-CPLXnickel ABC transporterIntegral Inner Membrane (B)NIKD_ECOLI
NIKC_ECOLI
NIKB_ECOLI
NIKA_ECOLI
NIKE_ECOLI
P33593
P0AFA9
P33591
P33590
P33594
[NikD][NikE][NikB][NikC][NikA]
step1694DMBPPRIBOSYLTRANS-CPLXnicotinate-nucleotide dimethylbenzimidazole phosphoribosyltransferaseCytoplasmic (A)COBT_ECOLIP36562[CobT]2
step1520CPLX0-7707NikR-Ni DNA binding transcriptional repressorNucleoid (N)NIKR_ECOLIP0A6Z6[(NikR)(Ni2+)]4
step1836NITRATREDUCTA-CPLXnitrate reductase AIntegral Inner Membrane (B)NARI_ECOLI
NARG_ECOLI
NARH_ECOLI
P11350
P09152
P11349
[NarI][(NarG)(NarH)]
step1837NITRATREDUCTZ-CPLXnitrate reductase ZIntegral Inner Membrane (B)NARZ_ECOLI
NARY_ECOLI
NARV_ECOLI
P19319
P19318
P0AF32
[NarY][NarZ][NarV]
step1838NITRITREDUCT-CPLXnitrite reductaseCytoplasmic (A)NIRD_ECOLI
NIRB_ECOLI
P0A9I8
P08201
[NirD][(NirB)2]
step1842NRFMULTI-CPLXnitrite reductase complexIntegral Inner Membrane (B)NRFC_ECOLI
NRFB_ECOLI
NRFD_ECOLI
NRFA_ECOLI
P0AAK7
P0ABL1
P32709
P0ABK9
[NrfD][NrfC][NrfB][NrfA]
step1883PII2-CPLXnitrogen regulatory protein GlnKPeripheral inner membrane protein facing the cytoplasm (F1)GLNK_ECOLIP0AC55[GlnK]3
step1884PIIPROTEIN-CPLXnitrogen regulatory protein P-II 1Cytoplasmic (A)GLNB_ECOLIP0A9Z1[GlnB]3
step2014N/ANlpI homodimerOuter Membrane Lipoprotein (I)NLPI_ECOLIP0AFB1[NlpI]2
step1665CPLXECOLI-7943NMN amidohydrolaseCytoplasmic (A)PNCC_ECOLIP0A6G3[YgaD]2
step1551CPLX0-7756NsrR DNA-binding transcriptional repressorNucleoid (N)NSRR_ECOLIP0AF63[NsrR]2
step1749GLNL-CPLXNtrB sensory histidine kinaseCytoplasmic (A)NTRB_ECOLIP0AFB5[GlnL]2
step1748GLNG-CPLXNtrC transcriptional dual regulatorNucleoid (N)NTRC_ECOLIP0AFB8[GlnG]2
step1893PROTEIN-NRIPNtrC-Phosphorylated DNA-binding transcriptional dual regulatorNucleoid (N)NTRC_ECOLIP0AFB8[GlnG]8
step1843NUCLEOSIDE-DIP-KIN-CPLXnucleoside diphosphate kinasePeripheral inner membrane protein facing the cytoplasm (F1)NDK_ECOLIP0A763[Ndk]4
step2060CPLX0-8106nucleoside triphosphate pyrophosphataseCytoplasmic (A)YHDE_ECOLIP25536[YhdE]2
step1511CPLX0-7692nucleoside triphosphate pyrophosphohydrolaseCytoplasmic (A)MAZG_ECOLIP0AEY3[MazG]2
step1604CPLX0-7879NusB-NusE complexRibosomal (r)RS10_ECOLI
NUSB_ECOLI
P0A7R5
P0A780
[RpsJ][NusB]
step1818MENE-CPLXo-succinylbenzoate-CoA ligasePeripheral inner membrane protein facing the cytoplasm (F1)MENE_ECOLIP37353[MenE]4
step1844O-SUCCHOMOSERLYASE-CPLXO-succinylhomoserine lyase / O-succinylhomoserine(thiol)-lyaseCytoplasmic (A)METB_ECOLIP00935[MetB]4
step1431CPLX0-7426octaprenyl diphosphate synthaseCytoplasmic (A)ISPB_ECOLIP0AD57[IspB]2
step1249CPLX0-1821oligoribonucleaseCytoplasmic (A)ORN_ECOLIP0A784[Orn]2
step2013N/AOmpA homodimerOuter Membrane b-barrel (H)OMPA_ECOLIP0A910[OmpA]2
step1882PHOSPHO-OMPROmpR-Phosphorylated DNA-binding transcriptional dual regulatorN,F1OMPR_ECOLIP0AA16[OmpR]2
step1845ORNCARBAMTRANSFERF-CPLXornithine carbamoyltransferase chain FCytoplasmic (A)OTC2_ECOLIP06960[ArgF]3
step1846ORNCARBAMTRANSFERI-CPLXornithine carbamoyltransferase chain ICytoplasmic (A)OTC1_ECOLIP04391[ArgI]3
step1847ORNDECARBOX-BIO-CPLXornithine decarboxylase, biosyntheticCytoplasmic (A)DCOR_ECOLIP21169[SpeC]2
step1848ORNDECARBOXDEG-CPLXornithine decarboxylase, degradativeCytoplasmic (A)DCOS_ECOLIP24169[SpeF]2
step2127N/Aornithine-dependent acid resistance system (ODAR)Integral Inner Membrane (B)DCOS_ECOLI
POTE_ECOLI
P24169
P0AAF1
[SpeF]2[PotE]2
step1849OROPRIBTRANS-CPLXorotate phosphoribosyltransferaseCytoplasmic (A)PYRE_ECOLIP0A7E3[PyrE]2
step1850OROTPDECARB-CPLXorotidine-5'-phosphate decarboxylaseCytoplasmic (A)PYRF_ECOLIP08244[PyrF]2
step1935N/Aosmoregulatory systemIntegral Inner Membrane (B)OMPR_ECOLI
ENVZ_ECOLI
P0AA16
P0AEJ4
[OmpR][EnvZ]
step1469CPLX0-7628outer membrane LPS assembly complexI&HLPTE_ECOLI
LPTD_ECOLI
P0ADC1
P31554
[LptD][LptE]
step1636CPLX0-7944outer membrane phospholipaseOuter Membrane b-barrel (H)PA1_ECOLIP0A921[PldA]2
step1444CPLX0-7530outer membrane pore protein EOuter Membrane b-barrel (H)PHOE_ECOLIP02932[PhoE]3
step1446CPLX0-7533outer membrane porin COuter Membrane b-barrel (H)OMPC_ECOLIP06996[OmpC]3
step1447CPLX0-7534outer membrane porin FOuter Membrane b-barrel (H)OMPF_ECOLIP02931[OmpF]3
step1390CPLX0-3933Outer Membrane Protein Assembly ComplexI&HBAMA_ECOLI
BAMC_ECOLI
BAMD_ECOLI
BAME_ECOLI
BAMB_ECOLI
P0A940
P0A903
P0AC02
P0A937
P77774
[SmpA][NlpB][YfiO][YaeT][YfgL]
step2061CPLX0-8009outer membrane protein; export and assembly of type 1 fimbriaeOuter Membrane b-barrel (H)FIMD_ECOLIP30130[FimD]2
step1603CPLX0-7878oxalyl-CoA decarboxylaseCytoplasmic (A)OXC_ECOLIP0AFI0[Oxc]4
step2062MONOMER0-2863oxidized ribonucleoside-triphosphate reductaseCytoplasmic (A)NRDD_ECOLIP28903[NrdD]2
step1595CPLX0-7844p-aminobenzoyl-glutamate hydrolaseCytoplasmic (A)ABGB_ECOLI
ABGA_ECOLI
P76052
P77357
[AbgB]2[AbgA]2
step2063CPLX0-7988PaaF-PaaG hydratase-isomerase complexCytoplasmic (A)PAAF_ECOLI
PAAG_ECOLI
P76082
P77467
[PaaG]6[PaaF]6
step1539CPLX0-7731PaaX DNA-binding transcriptional repressorNucleoid (N)PAAX_ECOLIP76086[PaaX]2
step1237CPLX0-1581palmitoyl transferase for Lipid AOuter Membrane b-barrel (H)PAGP_ECOLIP37001[PagP]2
step1854PANTOTHENATE-KIN-CPLXpantothenate kinaseCytoplasmic (A)COAA_ECOLIP0A6I3[CoaA]2
step1853PANTOATE-BETA-ALANINE-LIG-CPLXpantothenate synthetaseCytoplasmic (A)PANC_ECOLIP31663[PanC]2
step1852PABSYNMULTI-CPLXpara-aminobenzoate synthase multi-enzyme complexCytoplasmic (A)PABB_ECOLI
PABA_ECOLI
PABC_ECOLI
P05041
P00903
P28305
[(PabB)(PabA)][(PabC)2]
step1527CPLX0-7717penicillin-binding protein 1AIntegral Inner Membrane (B)PBPA_ECOLIP02918[PbpA]2
step1401CPLX0-3951penicillin-binding protein 1BIntegral Inner Membrane (B)PBPB_ECOLIP02919[PbpB]2
step1590CPLX0-7837PEP synthetase regulatory proteinCytoplasmic (A)YDIA_ECOLIP0A8A4[YdiA]4
step1325CPLX0-3001peptidase DCytoplasmic (A)PEPD_ECOLIP15288[PepD]2
step1329CPLX0-3041peptidase TCytoplasmic (A)PEPT_ECOLIP29745[PepT]2
step1048ABC-22-CPLXpeptide ABC transporter OppABCDFIntegral Inner Membrane (B)OPPF_ECOLI
OPPA_ECOLI
OPPD_ECOLI
OPPB_ECOLI
OPPC_ECOLI
P77737
P23843
P76027
P0AFH2
P0AFH6
[OppC][OppD][OppF][OppB][OppA]
step1055ABC-29-CPLXpeptide ABC transporter SapABCDFIntegral Inner Membrane (B)SAPB_ECOLI
SAPD_ECOLI
SAPF_ECOLI
SAPA_ECOLI
SAPC_ECOLI
P0AGH3
P0AAH4
P0AAH8
Q47622
P0AGH5
[SapF][SapD][SapB][SapC][SapA]
step1065ABC-41-CPLXpeptide ABC transporter YejABEFIntegral Inner Membrane (B)YEJE_ECOLI
YEJB_ECOLI
YEJF_ECOLI
YEJA_ECOLI
P33915
P0AFU0
P33916
P33913
[YejF]2[YejB][YejE][YejA]
step2064CPLX0-8097peptide antibiotic / peptide nucleic acid transporterIntegral Inner Membrane (B)SBMA_ECOLIP0AFY6[SbmA]2
step1831NAP-CPLXperiplasmic nitrate reductaseIntegral Inner Membrane (B)NAPC_ECOLI
NAPB_ECOLI
NAPH_ECOLI
NAPA_ECOLI
NAPG_ECOLI
P0ABL5
P0ABL3
P33934
P33937
P0AAL3
[(NapA)(NapB)][NapC][(NapG)(NapH)]
step1696DSBG-CPLXperiplasmic protein disulfide isomerase / proteindisulfide oxidoreductasePeriplasmic (G)DSBG_ECOLIP77202[DsbG]2
step1488CPLX0-7655phage lambda receptor protein; maltose high-affinity receptorOuter Membrane b-barrel (H)LAMB_ECOLIP02943[LamB]3
step1874PHENDEHYD-CPLXphenylacetaldehyde dehydrogenaseCytoplasmic (A)FEAB_ECOLIP80668[FeaB]2
step1875PHES-CPLXphenylalanyl-tRNA synthetaseCytoplasmic (A)SYFB_ECOLI
SYFA_ECOLI
P07395
P08312
[PheS]2[PheT]2
step1310CPLX0-255phenylhydantoinaseCytoplasmic (A)PHYDA_ECOLIQ46806[HyuA]4
step1876PHOR-CPLXPhoR sensory histidine kinaseIntegral Inner Membrane (B)PHOR_ECOLIP08400[PhoR]2
step1053ABC-27-CPLXphosphate ABC transporterIntegral Inner Membrane (B)PSTB_ECOLI
PSTA_ECOLI
PSTS_ECOLI
PSTC_ECOLI
P0AAH0
P07654
P0AG82
P0AGH8
[PstB]2[PstA][PstC][PstS]
step1616CPLX0-7912phosphate acetyltransferaseCytoplasmic (A)EUTD_ECOLIP77218[EutD]2
step1877PHOSACETYLTRANS-CPLXphosphate acetyltransferase / phosphatepropionyltransferaseIntegral Inner Membrane (B)PTA_ECOLIP0A9M8[Pta]6
step1879PHOSPHASERDECARB-CPLXphosphatidylserine decarboxylasePeripheral inner membrane protein facing the cytoplasm (F1)PSD_ECOLIP0A8K1[(Psd)(Psd)]
step1881PHOSPHASERSYN-CPLXphosphatidylserine synthasePeripheral inner membrane protein facing the cytoplasm (F1)PSS_ECOLIP23830[PssA]
step2065CPLX0-8109phosphodiesterase, c-di-GMP-specificNucleoid (N)YAHA_ECOLIP21514[YahA]2
step1871PEPCARBOX-CPLXphosphoenolpyruvate carboxylaseCytoplasmic (A)CAPP_ECOLIP00864[Ppc]4
step1872PEPSYNTH-CPLXphosphoenolpyruvate synthetaseCytoplasmic (A)PPSA_ECOLIP23538[PpsA]2
step1602CPLX0-7877phosphoglucose isomeraseCytoplasmic (A)G6PI_ECOLIP0A6T1[Pgi]2
step1895PSERTRANSAM-CPLXphosphohydroxythreonine aminotransferase / 3-phosphoserine aminotransferaseCytoplasmic (A)SERC_ECOLIP23721[SerC]2
step1067ABC-45-CPLXphospholipid ABC transporterIntegral Inner Membrane (B)MLAF_ECOLI
MLAE_ECOLI
MLAD_ECOLI
MLAB_ECOLI
MLAC_ECOLI
P63386
P64606
P64604
P64602
P0ADV7
[MlaC][MlaF]2[MlaE]2[MlaD][MlaB]2
step1936N/Aphospholipid metabolism complex PlsB-PssA-YbgC-acpPeripheral inner membrane protein facing the cytoplasm (F1)PSS_ECOLI
PLSB_ECOLI
ACP_ECOLI
YBGC_ECOLI
P23830
P0A7A7
P0A6A8
P0A8Z3
[PlsB][PssA][YbgC][Acp]
step1049ABC-23-CPLXphosphonate ABC transporterIntegral Inner Membrane (B)PHNC_ECOLI
PHND_ECOLI
PHNE_ECOLI
P16677
P16682
P16683
[PhnC]2[PhnE]2[PhnD]
step1180COADTRI-CPLXphosphopantetheine adenylyltransferaseCytoplasmic (A)COAD_ECOLIP0A6I6[CoaD]6
step1923SAICARSYN-CPLXphosphoribosylaminoimidazole-succinocarboxamide synthaseCytoplasmic (A)PUR7_ECOLIP0A7D7[PurC]3
step1114AIRS-CPLXphosphoribosylformylglycinamide cyclo-ligaseCytoplasmic (A)PUR5_ECOLIP08178[PurM]2
step2066CPLX0-7994poly-β-1,6-N-acetyl-D-glucosamine synthaseIntegral Inner Membrane (B)PGAD_ECOLI
PGAC_ECOLI
P69432
P75905
[PgaD][PgaC]
step1358CPLX0-3521polynucleotide phosphorylasePeripheral inner membrane protein facing the cytoplasm (F1)PNP_ECOLIP05055[Pnp]3
step1888PPK-CPLXpolyphosphate kinasePeripheral inner membrane protein facing the cytoplasm (F1)PPK_ECOLIP0A7B1[Ppk]4
step1887PORPHOBILSYNTH-CPLXporphobilinogen synthaseCytoplasmic (A)HEM2_ECOLIP0ACB2[HemB]8
step2138N/Apotential protein-folding maturation complex of DmsD and DnaJPeripheral inner membrane protein facing the cytoplasm (F1)DNAJ_ECOLI
DMSD_ECOLI
P69853
P08622
[DmsD][DnaJ]
step2137N/Apotential protein-folding maturation complex of DmsD and DnaKPeripheral inner membrane protein facing the cytoplasm (F1)DNAK_ECOLI
DMSD_ECOLI
P69853
P0A6Y8
[DmsD][DnaK]
step2142N/Apotential protein-folding maturation complex of DmsD and EftUPeripheral inner membrane protein facing the cytoplasm (F1)DMSD_ECOLI
EFTU1_ECOLI
P69853
P0CE47
[DmsD][TufA]
step2140N/Apotential protein-folding maturation complex of DmsD and GroELPeripheral inner membrane protein facing the cytoplasm (F1)DMSD_ECOLI
CH60_ECOLI
P69853
P0A6F5
[DmsD][GroEL]
step2139N/Apotential protein-folding maturation complex of DmsD and GrpEPeripheral inner membrane protein facing the cytoplasm (F1)GRPE_ECOLI
DMSD_ECOLI
P0AG07
P69853
[DmsD][GrpE]
step2141N/Apotential protein-folding maturation complex of DmsD and Trigger factorPeripheral inner membrane protein facing the cytoplasm (F1)TIG_ECOLI
DMSD_ECOLI
P69853
P0A850
[DmsD][Tig]
step1998N/APpiD homodimerIntegral Inner Membrane (B)PPID_ECOLIP0ADY1[PpiD]2
step1999N/APpiD homotrimerIntegral Inner Membrane (B)PPID_ECOLIP0ADY1[PpiD]3
step1997N/APpiD-YfgM unkown complexIntegral Inner Membrane (B)PPID_ECOLI
YFGM_ECOLI
P0ADY1
P76576
[PpiD][YfgM]
step1211CPLX-8401predicted 5-keto 4-deoxyuronate isomeraseCytoplasmic (A)KDUI_ECOLIQ46938[KduI]6
step1628CPLX0-7933predicted carbamoyltransferaseCytoplasmic (A)YGEW_ECOLIQ46803[YgeW]3
step1630CPLX0-7935predicted carbon-phosphorous lyase complexPeripheral inner membrane protein facing the cytoplasm (F1)PHNK_ECOLI
PHNG_ECOLI
PHNH_ECOLI
PHNI_ECOLI
PHNJ_ECOLI
P16678
P16685
P16686
P16687
P16688
[PhnK][PhnJ]2[PhnI]2[PhnH]2[PhnG]4
step1458CPLX0-7613predicted carboxysome structural proteinCytoplasmic (A)EUTN_ECOLIP0AEJ8[EutN]6
step1582CPLX0-7820predicted class I aldolaseCytoplasmic (A)LSRF_ECOLIP76143[LsrF]10
step2067CPLX0-7987predicted enamine/imine deaminaseCytoplasmic (A)TDCF_ECOLIP0AGL2[TdcF]3
step1253CPLX0-1881predicted enamine/imine deaminaseCytoplasmic (A)RIDA_ECOLIP0AF93[RidA]3
step1419CPLX0-661predicted hydrolaseIntegral Inner Membrane (B)YCAC_ECOLIP21367[YcaC]8
step1382CPLX0-3923predicted monooxygenaseCytoplasmic (A)YDHR_ECOLIP0ACX3[YdhR]2
step1496CPLX0-7668predicted oxidoreductaseCytoplasmic (A)YDJA_ECOLIP0ACY1[YdjA]2
step1428CPLX0-7422predicted rRNA methyltransferaseCytoplasmic (A)LAST_ECOLIP37005[LasT]2
step1570CPLX0-7801predicted structural protein, ethanolamine utilization micro compartmentCytoplasmic (A)EUTL_ECOLIP76541[EutL]3
step1588CPLX0-7835predicted structural protein, ethanolamine utilization microcompartmentCytoplasmic (A)EUTM_ECOLIP0ABF4[EutM]6
step1589CPLX0-7836predicted structural protein, ethanolamine utilization microcompartmentCytoplasmic (A)EUTS_ECOLIP63746[EutS]6
step1324CPLX0-3primosomal replication protein NCytoplasmic (A)PRIB_ECOLIP07013[PriB]2
step1381CPLX0-3922primosomeCytoplasmic (A)PRIM_ECOLI
DNAT_ECOLI
PRIB_ECOLI
PRIC_ECOLI
DNAB_ECOLI
PRIA_ECOLI
P0ABS5
P0A8J2
P07013
P23862
P0ACB0
P17888
[(DnaB)6][(DnaT)3][(PriB)2][PriA][PriC][DnaG]
step1465CPLX0-7624PrlF-YhaV antitoxin-toxin complexCytoplasmic (A)YHAV_ECOLIP64594[PrlF]2[YhaV]4
step1661CPLX0-902probable 4-oxalocrotonate tautomerase (4-OT)Cytoplasmic (A)PPTA_ECOLIP31992[PptA]2
step1331CPLX0-3081proline aminopeptidase P IICytoplasmic (A)AMPP_ECOLIP15034[PepP]4
step1892PROS-CPLXprolyl-tRNA synthetaseCytoplasmic (A)SYP_ECOLIP16659[ProS]2
step1557CPLX0-7766proofreading thioesterase in enterobactin biosynthesisCytoplasmic (A)ENTH_ECOLIP0A8Y8[EntH]4
step1477CPLX0-7642ProP osmosensory MFS transporterIntegral Inner Membrane (B)PROP_ECOLIP0C0L7[ProP]2
step1322CPLX0-2941protease IV, a signal peptide peptidaseIntegral Inner Membrane (B)SPPA_ECOLIP08395[SppA]4
step1568CPLX0-7799protease specific for YgjDCytoplasmic (A)YEAZ_ECOLIP76256[YeaZ]2
step2107N/Aprotein dissagregation chaperones complexCytoplasmic (A)IBPA_ECOLI
IBPB_ECOLI
P0C058
P0C054
[IbpA][IbpB]
step1695DSBC-CPLXprotein disulfide isomerase / protein disulfideoxidoreductasePeriplasmic (G)DSBC_ECOLIP0AEG6[DsbC]2
step2068CPLX0-8002protein disulfide isomerase/protein disulfide oxidoreductase - DsbCoxidisedPeriplasmic (G)DSBC_ECOLIP0AEG6[DsbC]2
step1453CPLX0-7597protein involved in a tRNA modification pathwayPeripheral inner membrane protein facing the cytoplasm (F1)MNMG_ECOLIP0A6U3[MnmG]2
step1577CPLX0-7811protoporphyrinogen oxidaseCytoplasmic (A)HEMG_ECOLIP0ACB4[HemG]4
step1937N/Apsp operon regulationIntegral Inner Membrane (B)PSPA_ECOLI
PSPB_ECOLI
PSPC_ECOLI
PSPD_ECOLI
P0AFM6
P0AFM9
P0AFN2
P0AFV8
[PspA][PspB][PspC][PspD]
step2129N/APsp self-hederodimer of large and small chainPeripheral inner membrane protein facing the cytoplasm (F1)PSD_ECOLI
ARGE_ECOLI
Y309_ECOLI
P0A8K1
P75688
P23908
[Psd (large chain) ][Psd (small chain)]
step1663CPLX0-961PspC transcriptional regulator; toxin of a PspC-PspB toxin-antitoxin pairIntegral Inner Membrane (B)PSPC_ECOLI
PSPB_ECOLI
P0AFN2
P0AFM9
[PspC]2
step1664CPLX0-981PspF DNA-binding transcriptional dual regulatorNucleoid (N)PSPF_ECOLIP37344[PspF]6
step2108N/APspF-PspA complexN,F1PSPA_ECOLI
PSPF_ECOLI
P37344
P0AFM6
[PspF][PspA]
step1632CPLX0-7938PTS enzyme IPeripheral inner membrane protein facing the cytoplasm (F1)PT1_ECOLIP08839[PtsI]2
step1188CPLX-159PTS permease - unknown specificityIntegral Inner Membrane (B)PTFLB_ECOLI
PTFA_ECOLI
P32154
P32155
[FrvB]2[FrvA]
step1189CPLX-160PTS permease - unknown specificityIntegral Inner Membrane (B)PTFB3_ECOLI
PTFC2_ECOLI
PTFB2_ECOLI
P32676
P32672
P69816
[FrwC]2[FrwB][FrwD]
step1707EIISGCPTS permease - unknown specificityIntegral Inner Membrane (B)SGCB_ECOLI
SGCC_ECOLI
SGCA_ECOLI
P58035
P39365
P39363
[SgcB][SgcC][SgcA]
step1550CPLX0-7755purine nucleoside phosphoramidaseCytoplasmic (A)HINT_ECOLIP0ACE7[HinT]2
step1680DEOD-CPLXpurine nucleoside phosphorylase deoD-typeCytoplasmic (A)DEOD_ECOLIP0ABP8[DeoD]6
step1862PC00033PurR transcriptional repressorCytoplasmic (A)PURR_ECOLIP0ACP7[PurR]2
step1281CPLX0-232putative arbutin PTS permeaseIntegral Inner Membrane (B)PTXB_ECOLI
PTXC_ECOLI
P69789
P31452
[GlvC]2[GlvB]
step1238CPLX0-1601putative selenate reductaseCytoplasmic (A)YNFH_ECOLI
YNFG_ECOLI
YNFF_ECOLI
YNFE_ECOLI
P76173
P0AAJ1
P77783
P77374
[YnfE][YnfF][YnfG][YnfH]
step1250CPLX0-1841putative selenate reductaseCytoplasmic (A)YGFM_ECOLI
YGFK_ECOLI
XDHD_ECOLI
P64557
Q46811
Q46814
[YgfK][XdhD][YgfM]
step1433CPLX0-7444putative structural proteinCytoplasmic (A)YCIF_ECOLIP21362[YciF]2
step1050ABC-24-CPLXputrescine / spermidine ABC transporterIntegral Inner Membrane (B)POTB_ECOLI
POTC_ECOLI
POTA_ECOLI
POTD_ECOLI
P0AFK4
P0AFK6
P69874
P0AFK9
[PotA]2[PotB][PotC][PotD]
step1051ABC-25-CPLXputrescine ABC transporterIntegral Inner Membrane (B)POTI_ECOLI
POTG_ECOLI
POTH_ECOLI
POTF_ECOLI
P0AFL1
P31134
P31135
P31133
[PotG]2[PotH][PotI][PotF]
step1899PYRNUTRANSHYDROGEN-CPLXpyridine nucleotide transhydrogenaseIntegral Inner Membrane (B)PNTA_ECOLI
PNTB_ECOLI
P07001
P0AB67
[PntB]2[PntA]2
step1977UDHA-CPLXpyridine nucleotide transhydrogenasePeripheral inner membrane protein facing the cytoplasm (F1)STHA_ECOLIP27306[SthA]8
step2069CPLX0-8031pyridoxal kinaseCytoplasmic (A)PDXY_ECOLIP77150[PdxY]2
step1870PDXK-CPLXpyridoxamine kinase / hydroxymethylpyrimidine kinase /pyridoxal kinaseCytoplasmic (A)PDXK_ECOLIP40191[PdxK]4
step1869PDXH-CPLXpyridoxine 5'-phosphate oxidase / pyridoxamine 5'-phosphate oxidaseCytoplasmic (A)PDXH_ECOLIP0AFI7[PdxH]2
step1342CPLX0-321pyridoxine 5'-phosphate synthaseCytoplasmic (A)PDXJ_ECOLIP0A794[PdxJ]8
step1900PYRROLINECARBREDUCT-CPLXpyrroline-5-carboxylate reductaseCytoplasmic (A)P5CR_ECOLIP0A9L8[ProC]10
step1901PYRUVATEDEH-CPLXpyruvate dehydrogenasePeripheral inner membrane protein facing the cytoplasm (F1)ODP2_ECOLI
ODP1_ECOLI
DLDH_ECOLI
P06959
P0AFG8
P0A9P0
[(AceE)2]12[AceF]24[(DldH)2]6
step1702E1P-CPLXpyruvate dehydrogenasePeripheral inner membrane protein facing the cytoplasm (F1)ODP1_ECOLIP0AFG8[AceE]2
step1902PYRUVFORMLY-INACTIVE-CPLXpyruvate formate-lyase (inactive)Cytoplasmic (A)PFLB_ECOLIP09373[PflB]2
step1111ADHE-CPLXpyruvate formate-lyase deactivase [multifunctional]Cytoplasmic (A)ADHE_ECOLIP0A9Q7[AdhE]40
step1885PKI-COMPLEXpyruvate kinase ICytoplasmic (A)KPYK1_ECOLIP0AD61[PykF]4
step1886PKII-CPLXpyruvate kinase IICytoplasmic (A)KPYK2_ECOLIP21599[PykA]4
step1338CPLX0-3141quinol monooxygenaseCytoplasmic (A)YGIN_ECOLIP0ADU2[YgiN]2
step1905QUINOPRIBOTRANS-CPLXquinolinate phosphoribosyltransferaseCytoplasmic (A)NADC_ECOLIP30011[NadC]2
step1529CPLX0-7719quinolinate synthaseCytoplasmic (A)NADA_ECOLIP11458[NadA]2
step1904QOR-CPLXquinone oxidoreductaseCytoplasmic (A)QOR1_ECOLIP28304[QorA]2
step1866PC00084RcsAB DNA-binding transcriptional dual regulatorN,F1RCSB_ECOLI
RCSA_ECOLI
P69407
P69405
[RcsB][RcsA]
step1619CPLX0-7916RcsB-BglJ DNA-binding transcriptional activatorN,F1RCSB_ECOLI
BGLJ_ECOLI
P69407
P39404
[BglJ][RcsB]
step2070CPLX0-7978RcsB-P-phosphateN,F1RCSB_ECOLIP69407[RcsB]2
step1606CPLX0-7884RcsB-phosphorylated DNA-binding transcriptional activatorN,F1RCSB_ECOLIP69407[RcsB]2
step1906RECBCDRecBCDCytoplasmic (A)EX5C_ECOLI
EX5B_ECOLI
EX5A_ECOLI
P07648
P08394
P04993
[RecD][RecC][RecB]
step1907RECFOR-CPLXRecFOR complexIntegral Inner Membrane (B)RECR_ECOLI
RECO_ECOLI
RECF_ECOLI
P0A7H6
P0A7H3
P0A7H0
[RecF][RecR][RecO]
step1213CPLX0-1reduced flavorubredoxinCytoplasmic (A)NORV_ECOLIQ46877[NorV]4
step1464CPLX0-7623regulator of acid resistance, influenced by indoleCytoplasmic (A)ARIR_ECOLIP75993[AriR]2
step1633CPLX0-7939regulator of KefC-mediated potassium transport andquinone oxidoreductaseIntegral Inner Membrane (B)KEFF_ECOLI
KEFC_ECOLI
P0A754
P03819
[KefF]2
step1553CPLX0-7758regulator of RNase III activityCytoplasmic (A)YMDB_ECOLIP0A8D6[YmdB]2
step1385CPLX0-3927regulatory ATPaseCytoplasmic (A)RAVA_ECOLIP31473[RavA]6
step1625CPLX0-7928RelB-antitoxin and DNA-binding transcriptional repressorNucleoid (N)RELB_ECOLIP0C079[RelB]4
step1562CPLX0-7791RelB-RelE antitoxin/toxin complex and DNA-binding transcriptional repressorNucleoid (N)RELE_ECOLI
RELB_ECOLI
P0C077
P0C079
[RelB]4[RelE]4
step1388CPLX0-3931Rep helicase, a single-stranded DNA dependent ATPaseNucleoid (N)REP_ECOLIP09980[Rep]2
step1364CPLX0-3621replicative DNA helicaseNucleoid (N)DNAB_ECOLIP0ACB0[DnaB]6
step2091N/AreplisomeNucleoid (N)DNAB_ECOLI
DNAG_ECOLI
HOLE_ECOLI
DPO3X_ECOLI
HOLD_ECOLI
HOLC_ECOLI
HOLB_ECOLI
HOLA_ECOLI
DPO3B_ECOLI
DPO3A_ECOLI
DPO3E_ECOLI
P0ACB0
P0ABS5
P0ABS8
P06710
P28632
P28905
P28631
P28630
P0A988
P10443
P03007
[DnaB][DnaG][(DnaE)(DnaQ)(HolE)]3[(DnaX)3(HolB)(HolA)][(DnaN)2]2[(DnaX)2][(HolC)(HolD)]4
step1921RUVABC-CPLXresolvasomeCytoplasmic (A)RUVC_ECOLI
RUVB_ECOLI
RUVA_ECOLI
P0A814
P0A812
P0A809
[RuvC]2[RuvB]4[RuvA]12
step2117N/ARespiratory complex 1Integral Inner Membrane (B)NUOJ_ECOLI
NUOK_ECOLI
NUOM_ECOLI
NUON_ECOLI
NUOL_ECOLI
NUOA_ECOLI
P33607
P0AFE4
P0AFF0
P0AFE0
P0AFE8
P0AFC3
[NuoL][NuoM][NuoN][NuoK][NuoJ][NuoA]
step1938N/Aresponce to stress complex RpoE-RseA-RsePIntegral Inner Membrane (B)RSEP_ECOLI
RSEA_ECOLI
RPOE_ECOLI
P0AEH1
P0AFX7
P0AGB6
[RpoE][RseA][RseP]
step1908RHAMNULPALDOL-CPLXrhamnulose-1-phosphate aldolaseCytoplasmic (A)RHAD_ECOLIP32169[RhaD]4
step1867PC00086RhaS transcriptional activatorNucleoid (N)RHAS_ECOLIP09377[RhaS]2
step1359CPLX0-3541RhlB, ATP-dependent RNA helicase of the RNA degradosomeNucleoid (N)RHLB_ECOLIP0A8J8[RhlB]2
step1402CPLX0-3952riboflavin synthaseCytoplasmic (A)RISA_ECOLIP0AFU8[RibE]3
step1482CPLX0-7647ribokinaseCytoplasmic (A)RBSK_ECOLIP0A9J6[RbsK]2
step1355CPLX0-3461ribonuclease EPeripheral inner membrane protein facing the cytoplasm (F1)RNE_ECOLIP21513[Rne]4
step1241CPLX0-1642ribonuclease E inhibitor protein ACytoplasmic (A)RRAA_ECOLIP0A8R0[RraA]3
step2071CPLX0-8096ribonuclease E inhibitor protein BCytoplasmic (A)RRAB_ECOLIP0AF90[RraB]2
step1239CPLX0-1621ribonuclease G (RNAse G)Cytoplasmic (A)RNG_ECOLIP0A9J0[Rng]2
step1911RIBONUCLEOSIDE-DIP-REDUCTI-CPLXribonucleoside diphosphate reductase 1Integral Inner Membrane (B)RIR2_ECOLI
RIR1_ECOLI
P69924
P00452
[(NrdA)2][(NrdB)2]
step1160B1-CPLXribonucleoside diphosphate reductase 1, α subunit dimerCytoplasmic (A)RIR1_ECOLIP00452[NrdA]2
step1161B2-CPLXribonucleoside diphosphate reductase 1, β subunit dimerCytoplasmic (A)RIR2_ECOLIP69924[NrdB]2
step1611CPLX0-7904ribonucleoside hydrolase 2 (pyrimidine-specific)Cytoplasmic (A)RIHB_ECOLIP33022[RihB]4
step1278CPLX0-229ribonucleoside triphosphate reductase activaseCytoplasmic (A)NRDG_ECOLIP0A9N8[NrdG]2
step1840NRDE-CPLXribonucleoside-diphosphate reductase 2Cytoplasmic (A)RIR3_ECOLIP39452[(NrdE)2]
step1841NRDF-CPLXribonucleoside-diphosphate reductase 2Cytoplasmic (A)RIR4_ECOLIP37146[(NrdF)2]
step1912RIBONUCLEOSIDE-DIP-REDUCTII-CPLXribonucleoside-diphosphate reductase 2Cytoplasmic (A)RIR4_ECOLI
RIR3_ECOLI
P37146
P39452
[(NrdE)2][(NrdF)2]
step1913RIBONUCLEOSIDE-TRIP-REDUCT-CPLXribonucleoside-triphosphate reductaseCytoplasmic (A)NRDD_ECOLIP28903[NrdD]2
step1054ABC-28-CPLXribose ABC transporterIntegral Inner Membrane (B)RBSA_ECOLI
RBSB_ECOLI
RBSC_ECOLI
P04983
P02925
P0AGI1
[RbsA]2[RbsC]2[RbsB]
step1481CPLX0-7646ribose pyranaseCytoplasmic (A)RBSD_ECOLIP04982[RbsD]10
step1909RIB5PISOMA-CPLXribose-5-phosphate isomerase ACytoplasmic (A)RPIA_ECOLIP0A7Z0[RpiA]2
step1638CPLX0-7946ribosomal protein S6 modification proteinCytoplasmic (A)RIMK_ECOLIP0C0U4[RimK]4
step1248CPLX0-1762ring 1,2-phenylacetyl-CoA epoxidaseCytoplasmic (A)PAAA_ECOLI
PAAC_ECOLI
PAAB_ECOLI
PAAE_ECOLI
P76077
P76079
P76078
P76081
[PaaE][PaaA][PaaC][PaaB]
step1272CPLX0-221RNA polymerase sigma 19N,F1RPOA_ECOLI
FECI_ECOLI
RPOB_ECOLI
RPOC_ECOLI
P0A7Z4
P23484
P0A8V2
P0A8T7
[(RpoA)2(RpoC)(RpoB)][FecI]
step1919RNAPE-CPLXRNA polymerase sigma 24N,F1RPOA_ECOLI
RPOB_ECOLI
RPOC_ECOLI
RPOE_ECOLI
P0A7Z4
P0A8V2
P0A8T7
P0AGB6
[(RpoA)2(RpoC)(RpoB)][RpoE]
step1273CPLX0-222RNA polymerase sigma 28N,F1RPOA_ECOLI
FLIA_ECOLI
RPOB_ECOLI
RPOC_ECOLI
P0A7Z4
P0AEM6
P0A8V2
P0A8T7
[FliA][(RpoA)2(RpoC)(RpoB)]
step1916RNAP32-CPLXRNA polymerase sigma 32N,F1RP32_ECOLI
RPOA_ECOLI
RPOB_ECOLI
RPOC_ECOLI
P0AGB3
P0A7Z4
P0A8V2
P0A8T7
[(RpoA)2(RpoC)(RpoB)][RpoH]
step1920RNAPS-CPLXRNA polymerase sigma 38N,F1RPOS_ECOLI
RPOA_ECOLI
RPOB_ECOLI
RPOC_ECOLI
P13445
P0A7Z4
P0A8V2
P0A8T7
[(RpoA)2(RpoC)(RpoB)][RpoS]
step1917RNAP54-CPLXRNA polymerase sigma 54N,F1RPOA_ECOLI
RPOB_ECOLI
RPOC_ECOLI
RP54_ECOLI
P0A7Z4
P0A8V2
P0A8T7
P24255
[(RpoA)2(RpoC)(RpoB)][RpoN]
step1918RNAP70-CPLXRNA polymerase sigma 70N,F1RPOA_ECOLI
RPOB_ECOLI
RPOC_ECOLI
RPOD_ECOLI
P0A7Z4
P0A8V2
P0A8T7
P00579
[(RpoA)2(RpoC)(RpoB)][RpoD]
step1128APORNAP-CPLXRNA polymerase, core enzymePeripheral inner membrane protein facing the cytoplasm (F1)RPOA_ECOLI
RPOB_ECOLI
RPOC_ECOLI
P0A7Z4
P0A8V2
P0A8T7
[RpoA]2[RpoC][RpoB]
step2072CPLX0-7998RNase adaptor proteinPeripheral inner membrane protein facing the cytoplasm (F1)YHBJ_ECOLIP0A894[RapZ]3
step1362CPLX0-3601RNase BNCytoplasmic (A)RBN_ECOLIP0A8V0[Rbn]2
step1347CPLX0-3281RNase IIICytoplasmic (A)RNC_ECOLIP0A7Y0[Rnc]2
step1215CPLX0-1081RNase PHCytoplasmic (A)RNPH_ECOLIP0CG19[Rph]
step1363CPLX0-3602RNase TCytoplasmic (A)RNT_ECOLIP30014[Rnt]2
step1614CPLX0-7909RnlA-RnlB toxin-antitoxin complexNucleoid (N)RNLA_ECOLI
RNLB_ECOLI
P52130
P52129
[YfjO][YfjN]
step2073CPLX0-7984S-glutathionyl-(chloro)hydroquinone reductaseCytoplasmic (A)YQJG_ECOLIP42620[YqjG]2
step1404CPLX0-3954S-lactoylglutathione hydrolase / S-formylglutathionehydrolaseCytoplasmic (A)SFGH2_ECOLIP33018[YeiG]4
step1407CPLX0-3957SbcCD ATP-dependent dsDNA exonucleasePeripheral inner membrane protein facing the cytoplasm (F1)SBCC_ECOLI
SBCD_ECOLI
P13458
P0AG76
[SbcC][SbcD]
step1574CPLX0-7807SdsRQP multidrug efflux systemB&IMDTO_ECOLI
MDTN_ECOLI
MDTP_ECOLI
P32715
P32716
P32714
[MdtP][MdtO][MdtN]
step1925SEC-SECRETION-CPLXSec Translocation ComplexIntegral Inner Membrane (B)YAJC_ECOLI
SECA_ECOLI
SECY_ECOLI
YIDC_ECOLI
SECB_ECOLI
SECE_ECOLI
SECD_ECOLI
SECG_ECOLI
SECF_ECOLI
P0ADZ7
P10408
P0AGA2
P25714
P0AG86
P0AG96
P0AG90
P0AG99
P0AG93
[SecB][SecA][(SecE)(SecG)(SecY)][(YidC)(YajC)(SecF)(SecD)]
step1939CPLX0-8089SecA dimeric statePeripheral inner membrane protein facing the cytoplasm (F1)SECA_ECOLIP10408[SecA]2
step2075CPLX0-8046SecBPeripheral inner membrane protein facing the cytoplasm (F1)SECB_ECOLIP0AG86[SecB]4
step1926SECD-SECF-YAJC-YIDC-CPLXSecD-SecF-YajC-YidC Secretion ComplexIntegral Inner Membrane (B)YAJC_ECOLI
YIDC_ECOLI
SECD_ECOLI
SECF_ECOLI
P0ADZ7
P25714
P0AG90
P0AG93
[YidC][YajC][SecF][SecD]
step1927SECE-G-Y-CPLXSecYEG translocaseIntegral Inner Membrane (B)SECY_ECOLI
SECE_ECOLI
SECG_ECOLI
P0AGA2
P0AG96
P0AG99
[SecE][SecG][SecY]
step1646CPLX0-7957selenide, water dikinaseCytoplasmic (A)SELD_ECOLIP16456[SelD]2
step1300CPLX0-246selenocysteine lyasePeripheral inner membrane protein facing the cytoplasm (F1)SUFS_ECOLIP77444[SufS]2
step1218CPLX0-1141selenocysteine synthaseCytoplasmic (A)SELA_ECOLIP0A821[SelA]10
step1995N/Aseptum inhibitor complex MinC-MinDPeripheral inner membrane protein facing the cytoplasm (F1)MINC_ECOLI
MIND_ECOLI
P18196
P0AEZ3
[MinC][MinD]
step2089N/ASeqA dimerPeripheral inner membrane protein facing the cytoplasm (F1)SEQA_ECOLIP0AFY8[SeqA]2
step1286CPLX0-237serine acetyltransferaseCytoplasmic (A)CYSE_ECOLIP0A9D4[CysE]6
step1771GLYOHMETRANS-CPLXserine hydroxymethyltransferaseCytoplasmic (A)GLYA_ECOLIP0A825[GlyA]2
step1321CPLX0-2921serine protease DoPeriplasmic (G)DEGP_ECOLIP0C0V0[DegP]6
step1928SERS-CPLXseryl-tRNA synthetaseCytoplasmic (A)SYS_ECOLIP0A8L1[SerS]2
step1438CPLX0-7462shikimate dehydrogenase / quinate dehydrogenaseCytoplasmic (A)YDIB_ECOLIP0A6D5[YdiB]2
step1245CPLX0-1669short chain acyl-CoA synthetasePeripheral inner membrane protein facing the cytoplasm (F1)FADK_ECOLIP38135[FadK]2
step1993N/Asidewall synthesis complex LpoA-PbpAB&ILPOA_ECOLI
PBPA_ECOLI
P02918
P45464
[LpoA][PbpA]
step2106N/ASigma(70) and Rsd complex formed in stationary phase.A,NRSD_ECOLI
RPOD_ECOLI
P00579
P0AFX4
[RpoD][Rsd]
step2122N/Asignal transduction system stimilated under lysine low levels Integral Inner Membrane (B)CADC_ECOLI
LYSP_ECOLI
P25737
P23890
[LysP][CadC]
step1524CPLX0-7711Skp periplasmic chaperonePeriplasmic (G)SKP_ECOLIP0AEU7[Skp]3
step2007N/ASlyB homomultimerOuter Membrane Lipoprotein (I)SLYB_ECOLIP0A905[SlyB]20
step2008N/ASlyB homomultimerOuter Membrane Lipoprotein (I)SLYB_ECOLIP0A905[SlyB]29
step2076CPLX0-8108small heat shock protein IbpA homodimerCytoplasmic (A)IBPA_ECOLIP0C054[IbpA]2
step2077CPLX0-8107small heat shock protein IbpB homodimerCytoplasmic (A)IBPB_ECOLIP0C058[IbpB]2
step2119N/ASoluble YbgFPeriplasmic (G)YBGF_ECOLIP45955[YbgF]3
step1930SORB6PDEHYDROG-CPLXsorbitol-6-phosphate dehydrogenaseCytoplasmic (A)SRLD_ECOLIP05707[SrlD]4
step1931SPERMACTRAN-CPLXspermidine acetyltransferaseCytoplasmic (A)ATDA_ECOLIP0A951[SpeG]4
step1932SPERMIDINESYN-CPLXspermidine synthaseCytoplasmic (A)SPEE_ECOLIP09158[SpeE]2
step1940SUCC-DEHASEsuccinate dehydrogenaseIntegral Inner Membrane (B)DHSB_ECOLI
DHSC_ECOLI
DHSA_ECOLI
DHSD_ECOLI
P07014
P69054
P0AC41
P0AC44
[SdhA][SdhB][SdhC][SdhD]
step1563CPLX0-7794succinate semialdehyde reductaseCytoplasmic (A)YIHU_ECOLIP0A9V8[YihU]4
step1509CPLX0-7688succinate-semialdehyde dehydrogenase (NADP+)Cytoplasmic (A)GABD_ECOLIP25526[GabD]4
step1941SUCCCOASYNsuccinyl-CoA synthetaseCytoplasmic (A)SUCD_ECOLI
SUCC_ECOLI
P0AGE9
P0A836
[SucD]2[SucC]2
step1639CPLX0-7947succinylarginine dihydrolaseCytoplasmic (A)ASTB_ECOLIP76216[AstB]2
step1942SUCCORNTRANSAM-CPLXsuccinylornithine transaminaseCytoplasmic (A)ASTC_ECOLIP77581[AstC]2
step1229CPLX0-1341SufBC2D Fe-S cluster scaffold complexPeripheral inner membrane protein facing the cytoplasm (F1)SUFD_ECOLI
SUFC_ECOLI
SUFB_ECOLI
P77689
P77499
P77522
[SufB][SufC]2[SufD]
step1230CPLX0-1342SufE homodimerPeripheral inner membrane protein facing the cytoplasm (F1)SUFE_ECOLIP76194[SufE]2
step1988N/Asulfane sulfur transfer complex of IscS and IscU (NifU)Cytoplasmic (A)ISCS_ECOLI
NIFU_ECOLI
P0A6B7
P0ACD4
[IscS][NifU]
step1087ABC-7-CPLXsulfate / thiosulfate ABC transporterIntegral Inner Membrane (B)CYSA_ECOLI
CYSP_ECOLI
CYSW_ECOLI
CYST_ECOLI
P16676
P16700
P0AEB0
P16701
[CysA]2[CysW][CysT][CysP]
step1088ABC-70-CPLXsulfate / thiosulfate ABC transporterIntegral Inner Membrane (B)SUBI_ECOLI
CYSA_ECOLI
CYSW_ECOLI
CYST_ECOLI
P0AG78
P16676
P0AEB0
P16701
[SubI][CysW][CysT][CysA]2
step2078CPLX0-7428sulfate adenylyltransferaseCytoplasmic (A)CYSD_ECOLI
CYSN_ECOLI
P21156
P23845
[(CysD)(CysN)]4
step1943SULFATE-ADENYLYLTRANS-CPLXsulfate adenylyltransferaseCytoplasmic (A)CYSN_ECOLI
CYSD_ECOLI
P23845
P21156
[(CysD)(CysN)]4
step1944SULFITE-REDUCT-CPLXsulfite reductaseCytoplasmic (A)CYSI_ECOLI
CYSJ_ECOLI
P17846
P38038
[(CysJ)8][CysI]4
step1593CPLX0-7841sulfite reductase, flavoprotein subunit complexCytoplasmic (A)CYSJ_ECOLIP38038[CysJ]8
step1199CPLX-3942sulfur transfer protein complexCytoplasmic (A)TUSC_ECOLI
TUSD_ECOLI
TUSB_ECOLI
P45531
P45532
P45530
[TusB]2[TusC]2[TusD]2
step1945SUPEROX-DISMUTFE-CPLXsuperoxide dismutase (Fe)Cytoplasmic (A)SODF_ECOLIP0AGD3[SodB]2
step1946SUPEROX-DISMUTMN-CPLXsuperoxide dismutase (Mn)Periplasmic (G)SODM_ECOLIP00448[SodA]2
step1289CPLX0-240tagatose-1,6-bisphosphate aldolase 1Cytoplasmic (A)KBAY_ECOLI
KBAZ_ECOLI
P0AB74
P0C8K0
[KbaY][KbaZ]
step1291CPLX0-241tagatose-1,6-bisphosphate aldolase 2Cytoplasmic (A)GATZ_ECOLI
GATY_ECOLI
P0C8J8
P0C8J6
[GatY][GatZ]
step1461CPLX0-7616tartronate semialdehyde reductase 2Cytoplasmic (A)GLXR_ECOLIP77161[GlxR]4
step1949TATABCE-CPLXTatABCE protein export complexIntegral Inner Membrane (B)TATA_ECOLI
TATE_ECOLI
TATB_ECOLI
TATC_ECOLI
P69428
P0A843
P69425
P69423
[TatB][TatC][TatE][TatA]
step1086ABC-64-CPLXtaurine ABC transporterIntegral Inner Membrane (B)TAUC_ECOLI
TAUA_ECOLI
TAUB_ECOLI
Q47539
Q47537
Q47538
[TauA][TauC]2[TauB]2
step1277CPLX0-227taurine dioxygenaseCytoplasmic (A)TAUD_ECOLIP37610[TauD]2
step1617CPLX0-7913tellurite methyltransferaseCytoplasmic (A)TEHB_ECOLIP25397[TehB]2
step1340CPLX0-3181tetrahydrodipicolinate succinylaseCytoplasmic (A)DAPD_ECOLIP0A9D8[DapD]2
step1274CPLX0-2221The Colicin A Import SystemProtein complex spanning both membranesOMPF_ECOLI
TOLR_ECOLI
PAL_ECOLI
TOLA_ECOLI
TOLB_ECOLI
YBGF_ECOLI
BTUB_ECOLI
TOLQ_ECOLI
P02931
P0ABV6
P0A912
P19934
P0A855
P45955
P06129
P0ABU9
[BtuB][(OmpF)3][(TolA)(TolQ)(TolR)(TolB)(YbgF)(Pal)]
step1270CPLX0-2201The Tol-Pal Cell Envelope ComplexProtein complex spanning both membranesTOLR_ECOLI
PAL_ECOLI
TOLA_ECOLI
TOLB_ECOLI
YBGF_ECOLI
TOLQ_ECOLI
P0ABV6
P0A912
P19934
P0A855
P45955
P0ABU9
[TolA][TolQ][TolR][TolB][YbgF][Pal]
step1058ABC-32-CPLXthiamin ABC transporterIntegral Inner Membrane (B)THIQ_ECOLI
THIP_ECOLI
P31548
P31549
[ThiQ]2[ThiP]2[TbpA]
step1399CPLX0-3949thiazole synthaseCytoplasmic (A)THIH_ECOLI
THIG_ECOLI
P30140
P30139
[(ThiG)(ThiH)]6
step1208CPLX-8029thiazole synthaseCytoplasmic (A)THIH_ECOLI
THIG_ECOLI
P30140
P30139
[(ThiG)(ThiH)]6
step1950THIOESTERII-CPLXthioesterase IICytoplasmic (A)TESB_ECOLIP0AGG2[TesB]4
step1951THIOREDOXIN-REDUCT-NADPH-CPLXthioredoxin reductasePeriplasmic (G)TRXB_ECOLIP0A9P4[TrxB]2
step1292CPLX0-242thiosulfate sulfurtransferaseCytoplasmic (A)GLPE_ECOLIP0A6V5[GlpE]2
step1953THREDEHYDSYN-CPLXthreonine deaminaseIntegral Inner Membrane (B)ILVA_ECOLIP04968[IlvA]4
step1954THREODEHYD-CPLXthreonine dehydrogenaseCytoplasmic (A)TDH_ECOLIP07913[Tdh]4
step1955THRS-CPLXthreonyl-tRNA synthetaseCytoplasmic (A)SYT_ECOLIP0A8M3[ThrS]2
step1679DEOA-CPLXthymidine phosphorylase / uracil phosphorylaseCytoplasmic (A)TYPH_ECOLIP07650[DeoA]2
step1956THYMIDYLATESYN-CPLXthymidylate synthaseCytoplasmic (A)TYSY_ECOLIP0A884[ThyA]2
step2120N/ATolA-YbgF complexIntegral Inner Membrane (B)YBGF_ECOLI
TOLA_ECOLI
P45955
P19934
[TolA][YbgF]2
step1653CPLX0-7964TolC outer membrane channelOuter Membrane b-barrel (H)TOLC_ECOLIP02930[TolC]3
step1254CPLX0-1923TonB energy transducing systemIntegral Inner Membrane (B)EXBD_ECOLI
TONB_ECOLI
EXBB_ECOLI
P0ABV2
P02929
P0ABU7
[TonB][ExbB][ExbD]
step2113N/ATonB-dependent import of ferrichrome.Protein complex spanning both membranesTONB_ECOLI
FHUA_ECOLI
P06971
P02929
[TonB][FhuA]
step1294CPLX0-2424topoisomerase IVPeripheral inner membrane protein facing the cytoplasm (F1)PARE_ECOLI
PARC_ECOLI
P20083
P0AFI2
[ParE]2[(ParC)2]
step2110N/ATorA/TorD complexCytoplasmic (A)TORD_ECOLI
TORA_ECOLI
P36662
P33225
[TorA][TorD]
step1958TORR-CPLXTorR transcriptional dual regulatorNucleoid (N)TORR_ECOLIP38684[TorR]2
step1959TORS-CPLXTorS sensory histidine kinaseIntegral Inner Membrane (B)TORS_ECOLIP39453[TorS]2
step2109N/ATorS/TorR phosphorelay systemIntegral Inner Membrane (B)TORS_ECOLI
TORC_ECOLI
P39453
P33226
[TorC][TorS]
step1966TRANSALDOLB-CPLXtransaldolase BCytoplasmic (A)TALB_ECOLIP0A870[TalB]2
step1298CPLX0-2441transcription termination factor RhoCytoplasmic (A)RHO_ECOLIP0AG30[Rho]6
step1967TRANSKETOI-CPLXtransketolase ICytoplasmic (A)TKT1_ECOLIP27302[TktA]2
step1226CPLX0-1261transketolase IICytoplasmic (A)TKT2_ECOLIP33570[TktB]
step2080CPLX0-7976translocation and assembly moduleProtein complex spanning both membranesTAMA_ECOLI
TAMB_ECOLI
P0ADE4
P39321
[TamB][TamA]
step1410CPLX0-3961transthyretin-related proteinPeriplasmic (G)HIUH_ECOLIP76341[HiuH]4
step1195CPLX-168trehalose PTS permeaseIntegral Inner Membrane (B)PTTBC_ECOLI
PTGA_ECOLI
P36672
P69783
[TreB]2[Crr]
step1600CPLX0-7854TreR DNA-binding transcriptional repressorCytoplasmic (A)TRER_ECOLIP36673[TreR]2
step2081ALPHA-SUBUNIT-CPLXtrimer complex of formate dehydrogenase-N α, β and γ subunitsIntegral Inner Membrane (B)FDNI_ECOLI
FDNG_ECOLI
FDNH_ECOLI
P0AEK7
P24183
P0AAJ3
[(FdnI)(FdnH)(FdnG)]3
step1957TMAOREDUCTI-CPLXtrimethylamine N-oxide reductase IIntegral Inner Membrane (B)TORC_ECOLI
TORA_ECOLI
P33226
P33225
[TorC][TorA]2
step1203CPLX-63trimethylamine N-oxide reductase IIIIntegral Inner Membrane (B)TORY_ECOLI
TORZ_ECOLI
P52005
P46923
[TorZ][TorY]
step1960TPItriose phosphate isomeraseCytoplasmic (A)TPIS_ECOLIP0A858[TpiA]2
step1427CPLX0-7421tRNA (cytidine/uridine-2'-O)-ribose methyltransferaseCytoplasmic (A)TRML_ECOLIP0AGJ7[TrmL]2
step1400CPLX0-3950tRNA m1G37 methyltransferaseCytoplasmic (A)TRMD_ECOLIP0A873[TrmD]2
step1538CPLX0-7728tRNA pseudouridine synthase ICytoplasmic (A)TRUA_ECOLIP07649[TruA]2
step1426CPLX0-7420tRNA Um32 methyltransferase / tRNA Cm32methyltransferaseCytoplasmic (A)TRMJ_ECOLIP0AE01[TrmJ]2
step1216CPLX0-1101tRNA-guanine transglycosylaseCytoplasmic (A)TGT_ECOLIP0A847[Tgt]3
step1660CPLX0-901tRNA-specific adenosine deaminaseCytoplasmic (A)TADA_ECOLIP68398[TadA]2
step1859PC00007TrpR transcriptional repressorNucleoid (N)TRPR_ECOLIP0A881[TrpR]2
step1970TRYPSYNtryptophan synthaseCytoplasmic (A)TRPB_ECOLI
TRPA_ECOLI
P0A879
P0A877
[TrpA]2[(TrpB)2]
step1290CPLX0-2401tryptophan synthase, β subunit dimerCytoplasmic (A)TRPB_ECOLIP0A879[TrpB]2
step1969TRPS-CPLXtryptophanyl-tRNA synthetaseCytoplasmic (A)SYW_ECOLIP00954[TrpS]2
step2092N/ATus-DnaBNucleoid (N)TUS_ECOLI
DNAB_ECOLI
P16525
P0ACB0
[Tus][DnaB]
step2111N/ATwo component regulatory system AcrA-AcrBB&EACRA_ECOLI
ACRB_ECOLI
P31224
P0AE06
[AcrA][AcrB]
step1975TYRB-DIMERtyrosine aminotransferaseCytoplasmic (A)TYRB_ECOLIP04693[TyrB]2
step1976TYRS-CPLXtyrosyl-tRNA synthetaseCytoplasmic (A)SYY_ECOLIP0AGJ9[TyrS]2
step2082CPLX0-8016UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferaseCytoplasmic (A)LPXD_ECOLIP21645[LpxD]3
step1978UDPGLUCEPIM-CPLXUDP-glucose 4-epimeraseCytoplasmic (A)UDP_ECOLI
GALE_ECOLI
P12758
P09147
[GalE]2
step2085CPLX0-8098UDP-glucose 6-dehydrogenaseCytoplasmic (A)UDG_ECOLIP76373[Ugd]2
step1528CPLX0-7718UDP-L-Ara4N formyltransferase / UDP-GlcA C-4"-decarboxylaseIntegral Inner Membrane (B)ARNA_ECOLI
UDP_ECOLI
GLCA_ECOLI
P77398
P12758
Q46839
[ArnA]6
step2086CPLX0-8013UDP-N-acetyl-D-mannosaminuronic acid dehydrogenaseOuter Membrane b-barrel (H)WECC_ECOLIP27829[WecC]2
step2083CPLX0-8008UDP-N-acetylglucosamine 2-epimeraseCytoplasmic (A)WECB_ECOLIP27828[WecB]2
step1979UDPNACETYLGLUCOSAMACYLTRANS-CPLXUDP-N-acetylglucosamine acyltransferaseCytoplasmic (A)LPXA_ECOLIP0A722[LpxA]3
step2084CPLX0-8014UDP-N-acetylmuramate-alanine ligaseF1*MURC_ECOLIP17952[MurC]2
step1549CPLX0-7754UhpA-Phosphorylated DNA-binding transcriptional activatorNucleoid (N)UHPA_ECOLIP0AGA6[UhpA]2
step1981UPPSYN-CPLXundecaprenyl diphosphate synthaseCytoplasmic (A)UPPS_ECOLIP60472[UppS]2
step2087CPLX0-8011undecaprenyl-phosphate α-N-acetylglucosaminyl transferaseIntegral Inner Membrane (B)WECA_ECOLIP0AC78[WecA]2
step1395CPLX0-3939universal stress protein UP12Cytoplasmic (A)USPG_ECOLIP39177[UspG]2
step1982URACIL-PRIBOSYLTRANS-CPLXuracil phosphoribosyltransferaseCytoplasmic (A)UPP_ECOLIP0A8F0[Upp]3
step2088CPLX0-7993ureidoglycolate dehydrogenaseCytoplasmic (A)ALLD_ECOLIP77555[AllD]2
step1983URPHOS-CPLXuridine phosphorylaseCytoplasmic (A)UDP_ECOLIP12758[Udp]6
step1980UMPKI-CPLXuridylate kinasePeripheral inner membrane protein facing the cytoplasm (F1)PYRH_ECOLIP0A7E9[PyrH]6
step1929SIROHEMESYN-CPLXuroporphyrin III C-methyltran