STEPdb: Sub-cellular Topologies of E.coli Polypeptides.

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E.coli K-12 (MG1655) Exportome

(mouse over and click on the one letter topology symbols to see which proteins of this specific subproteome are localized in each location)

Bacterial cell cartoon of sub-cellular locations


Protein ID
(Uniprot)
Accession
(Uniprot)
Gene Name
(Uniprot)
Order
Locus Name
Protein Name
(STEPdb)
Full Name
Symbol
Uniprot
EchoLOCATION
Extracellular Appendage
First Level
Targeting
Chaperoning
First Level
Secretion
System
Second Level
Targeting
Chaperoning
Second Level
Secretion
System
K-12 Core
Proteome
(yes/no)
K-12 Basic
Proteome
(yes/no)
FIMH_ECOLI
P08191
fimH
b4320 JW4283
Fimbrial extra-cellular peripheral OM protein (SEC through IM, chaperone usher export system over OM), Type 1 fimbrin D-mannose specific adhesin FimH
Peripheral outer membrane protein facing the extra-cellular space
F4
N/A
Fimbrium
Cell surface appendage (Experimental)
fimbriae
 
SEC
 
CU
no
yes
YEAL_ECOLI
P0ACY6
yeaL
b1789 JW1778
integral IM protein (SEC in IM), UPF0756 YeaL
Integral Inner Membrane
B
IM (predicted)
Cell membrane
Integral Membrane Protein
 
SRP
SEC
 
 
no
yes
YOHC_ECOLI
P0AD17
yohC
b2135 JW5356
integral IM protein (SEC in IM), YohC
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane; Multi-pass membrane protein
Integral Membrane Protein (Experimental)
 
SRP
SEC
 
 
yes
yes
YPHA_ECOLI
P0AD47
yphA
b2543 JW2527
integral IM protein (SEC in IM), YphA
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane; Multi-pass membrane protein
Integral Membrane Protein (Experimental)
 
SRP
SEC
 
 
yes
yes
GLPT_ECOLI
P08194
glpT
b2240 JW2234
integral IM protein (SEC in IM), Glycerol-3-phosphate transporter GlpT
Integral Inner Membrane
B
IM (predicted), Detected in IM Fraction
Cell inner membrane; Multi-pass membrane protein
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
CPDB_ECOLI
P08331
cpdB
b4213 JW4171
periplasmic protein (SEC through IM), 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase CpdB
Periplasmic
G
N/A
Periplasm
Periplasmic (Experimental)
 
 
SEC
SURA
 
no
yes
CRED_ECOLI
P08369
creD

cet

b4400 JW4363
integral IM protein (SEC-YidC in IM), CreD
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane; Multi-pass membrane protein
Integral Membrane Protein
 
SRP
SEC-YidC
 
 
no
yes
SPPA_ECOLI
P08395
sppA
b1766 JW1755
integral IM protein (SEC in IM), Protease 4 SppA
Integral Inner Membrane
B
IM (predicted), Detected in IM Fraction
Cell inner membrane
Membrane anchored
 
SRP
SEC
 
 
yes
yes
OSMB_ECOLI
P0ADA7
osmB
b1283 JW1275
OM lipoprotein (SEC through IM), inserted in OM by LOL), Osmotically-inducible B OsmB
Outer Membrane Lipoprotein
I
N/A
Cell membrane
Outer membrane Lipoprotein (Experimental)
 
 
SEC
 
LOL
no
yes
ECNA_ECOLI
P0ADB4
ecnA
b4410 JW5737
OM lipoprotein (SEC through IM), inserted in OM by LOL), Entericidin A EcnA
Outer Membrane Lipoprotein
I
N/A
Cell membrane; Lipid-anchor
Outer membrane Lipoprotein (Experimental)
 
 
SEC
 
LOL
no
yes
PHOR_ECOLI
P08400
phoR

nmpB

b0400 JW0390
integral IM protein (SEC in IM), Phosphate regulon sensor PhoR PhoR
Integral Inner Membrane
B
N/A
Cell inner membrane
Membrane anchored
 
SRP
SEC
 
 
yes
yes
CREC_ECOLI
P08401
creC

phoM

b4399 JW4362
integral IM protein (SEC-YidC in IM), Sensor CreC
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane; Multi-pass membrane protein
Integral Membrane Protein
 
SRP
SEC-YidC
 
 
yes
yes
DACC_ECOLI
P08506
dacC
b0839 JW0823
periplasmic peripheral IM protein (SEC through IM), D-alanyl-D-alanine carboxypeptidase DacC
Peripheral inner membrane protein facing the periplasm
F2
Soluble IM Fraction
Cell inner membrane
Membrane anchored (Experimental)
 
 
SEC
 
 
yes
yes
YJJB_ECOLI
P0ADD2
yjjB
b4363 JW4327
integral IM protein (SEC in IM), UPF0442 YjjB
Integral Inner Membrane
B
IM (predicted)
Cell membrane
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
YHHN_ECOLI
P0ADI9
yhhN
b3468 JW3433
integral IM protein (SEC in IM), YhhN
Integral Inner Membrane
B
IM (predicted)
Cell membrane
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
BCSF_ECOLI
P0ADJ5
bcsF

yhjT

b3537 JW5663
integral IM protein (SEC in IM), Cellulose biosynthesis BcsF
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane
Membrane anchored
 
SRP
SEC
 
 
no
yes
YIAA_ECOLI
P0ADJ8
yiaA
b3562 JW3534
integral IM protein (SEC in IM), YiaA
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane; Multi-pass membrane protein
Integral Membrane Protein
 
SRP
SEC
 
 
no
yes
CVPA_ECOLI
P08550
cvpA

dedE

b2313 JW2310
integral IM protein (SEC in IM), Colicin V production CvpA
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane; Multi-pass membrane protein
Integral Membrane Protein (Experimental)
 
SRP
SEC
 
 
yes
yes
DSDX_ECOLI
P08555
dsdX

orf445 yfdA yfdD

b2365 JW2362
integral IM protein (SEC in IM), D-serine transporter DsdX
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane
Integral Membrane Protein (Experimental)
 
SRP
SEC
 
 
no
yes
PTV3B_ECOLI
P08722
bglF

bglC bglS

b3722 JW3700
integral IM protein (SEC in IM), PTS system beta-glucoside-specific EIIBCA component BglF
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane; Multi-pass membrane protein
Integral Membrane Protein
 
SRP
SEC
 
 
no
yes
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