STEPdb: Sub-cellular Topologies of E.coli Polypeptides.

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E.coli K-12 (MG1655) Exportome

(mouse over and click on the one letter topology symbols to see which proteins of this specific subproteome are localized in each location)

Bacterial cell cartoon of sub-cellular locations


Protein ID
(Uniprot)
Accession
(Uniprot)
Gene Name
(Uniprot)
Order
Locus Name
Protein Name
(STEPdb)
Full Name
Symbol
Uniprot
EchoLOCATION
Extracellular Appendage
First Level
Targeting
Chaperoning
First Level
Secretion
System
Second Level
Targeting
Chaperoning
Second Level
Secretion
System
K-12 Core
Proteome
(yes/no)
K-12 Basic
Proteome
(yes/no)
HEMX_ECOLI
P09127
hemX
b3803 JW3775
integral IM protein (SEC in IM), HemX
Integral Inner Membrane
B
IM (predicted), Detected in IM Fraction
Cell inner membrane
Membrane anchored
 
SRP
SEC
 
 
no
yes
YIAW_ECOLI
P0ADK4
yiaW
b3587 JW3559
integral IM protein (SEC in IM), YiaW
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane; Multi-pass membrane protein
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
YICN_ECOLI
P0ADL3
yicN
b3663 JW5637
integral IM protein (SEC in IM), YicN
Integral Inner Membrane
B
N/A
 
Membrane anchored
 
SRP
SEC
 
 
yes
yes
YIDG_ECOLI
P0ADL6
yidG
b3675 JW3651
integral IM protein (SEC in IM), YidG
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane; Multi-pass membrane protein
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
YIDH_ECOLI
P0ADM0
yidH
b3676 JW3652
integral IM protein (SEC in IM), YidH
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane; Multi-pass membrane protein
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
OMPT_ECOLI
P09169
ompT
b0565 JW0554
OM b-barrel protein (SEC through IM, inserted in OM by BAM), Protease 7 OmpT
Outer Membrane b-barrel protein
H
Soluble IM Fraction
Cell outer membrane; Multi-pass membrane protein
Outer Membrane ??-barrel protein (Experimental)
 
SECB,TF
SEC
 
BAM
no
no
PTW3C_ECOLI
P09323
nagE

pstN

b0679 JW0665
integral IM protein (SEC in IM), PTS system N-acetylglucosamine-specific EIICBA component NagE
Integral Inner Membrane
B
IM (predicted), Detected in IM Fraction
Cell inner membrane
Integral Membrane Protein (Experimental)
 
SRP
SEC
 
 
yes
yes
MOTA_ECOLI
P09348
motA

flaJ

b1890 JW1879
integral IM protein (SEC in IM), Motility A MotA
Integral Inner Membrane
B
IM (predicted), Detected in IM Fraction
Cell inner membrane; Multi-pass membrane protein
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
GLPG_ECOLI
P09391
glpG
b3424 JW5687
integral IM protein (SEC in IM), Rhomboid protease GlpG
Integral Inner Membrane
B
IM (predicted), Detected in IM Fraction
Cell inner membrane
Integral Membrane Protein
 
SRP (exp)
SEC
 
 
yes
yes
YIDQ_ECOLI
P0ADM4
yidQ
b3688 JW5633
IM lipoprotein (SEC through IM, inserted in OM by LOL), YidQ
Inner Membrane Lipoprotein
E
N/A
 
Outer membrane Lipoprotein(experimental)
 
 
SEC
 
LOL
yes
yes
YIDX_ECOLI
P0ADM6
yidX
b3696 JW5858
OM lipoprotein (SEC through IM, inserted in OM by LOL), YidX
Outer Membrane Lipoprotein
I
N/A
Membrane
Outer membrane Lipoprotein
 
 
SEC
 
LOL
no
yes
GLPQ_ECOLI
P09394
glpQ
b2239 JW2233
periplasmic protein (SEC through IM), Glycerophosphodiester phosphodiesterase, periplasmic GlpQ
Periplasmic
G
N/A
Periplasm
Periplasmic (Experimental)
 
 
SEC
 
 
yes
yes
DEDD_ECOLI
P09549
dedD
b2314 JW5378
integral IM protein (SEC in IM), Cell division DedD
Integral Inner Membrane
B
IM (predicted), Detected in IM Fraction
Cell inner membrane
Membrane anchored
 
SRP
SEC
 
 
yes
yes
ARGT_ECOLI
P09551
argT
b2310 JW2307
periplasmic protein (SEC through IM), Lysine/arginine/ornithine-binding periplasmic ArgT
Periplasmic
G
N/A
Periplasm
Periplasmic (Experimental)
 
 
SEC
 
 
yes
yes
UHPB_ECOLI
P09835
uhpB
b3668 JW3643
integral IM protein (SEC in IM), Signal transduction histidine-kinase/phosphatase UhpB
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
YGAM_ECOLI
P0ADQ7
ygaM
b2672 JW2647
integral IM protein (SEC in IM), YgaM
Integral Inner Membrane
B
IM (predicted), Detected in IM Fraction
Cell inner membrane
Membrane anchored
 
SRP
SEC
 
 
no
yes
YGGE_ECOLI
P0ADS6
yggE
b2922 JW2889
periplasmic protein (SEC through IM), YggE
Periplasmic
G
N/A
 
Periplasmic
 
 
SEC
 
 
yes
yes
YGIW_ECOLI
P0ADU5
ygiW
b3024 JW2992
periplasmic protein (SEC through IM), YgiW
Periplasmic
G
N/A
Periplasm
Periplasmic (Experimental)
 
SECB
SEC
 
 
yes
yes
UHPC_ECOLI
P09836
uhpC
b3667 JW3642
integral IM protein (SEC in IM), sensor UhpC
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
UBIB_ECOLI
P0A6A0
ubiB

aarF yigQ yigR yigS

b3835 JW3812
integral IM protein (SEC in IM), Probable kinase UbiB
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
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