STEPdb: Sub-cellular Topologies of E.coli Polypeptides.

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E.coli K-12 (MG1655) Exportome

(mouse over and click on the one letter topology symbols to see which proteins of this specific subproteome are localized in each location)

Bacterial cell cartoon of sub-cellular locations


Protein ID
(Uniprot)
Accession
(Uniprot)
Gene Name
(Uniprot)
Order
Locus Name
Protein Name
(STEPdb)
Full Name
Symbol
Uniprot
EchoLOCATION
Extracellular Appendage
First Level
Targeting
Chaperoning
First Level
Secretion
System
Second Level
Targeting
Chaperoning
Second Level
Secretion
System
K-12 Core
Proteome
(yes/no)
K-12 Basic
Proteome
(yes/no)
YGBN_ECOLI
Q46892
ygbN
b2740 JW2710
integral IM protein (SEC in IM), permease YgbN
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane; Multi-pass membrane protein
Integral Membrane Protein (Experimental)
 
SRP
SEC
 
 
yes
yes
YGCS_ECOLI
Q46909
ygcS
b2771 JW5845
integral IM protein (SEC in IM), metabolite transport YgcS
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane; Multi-pass membrane protein
Integral Membrane Protein
 
SRP
SEC
 
 
no
yes
GUDP_ECOLI
Q46916
gudP

ygcZ

b2789 JW2760
integral IM protein (SEC in IM), Probable glucarate transporter GudP
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane; Multi-pass membrane protein
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
TCDA_ECOLI
Q46927
tcdA

csdL, ygdL

b2812 JW2783
integral IM protein (SEC in IM), tRNA threonylcarbamoyladenosine dehydratase TcdA
Integral Inner Membrane
B
IM (predicted)
Membrane
Membrane anchored
 
 
SEC
 
 
yes
yes
YQEI_ECOLI
Q46942
yqeI
b2847 JW2815
nucleoid & integral IM protein (SEC in IM), YqeI
Integral Inner Membrane, Nucleoid
B, N
IM (predicted)
 
Cytoplasmic
 
SRP
SEC
 
 
no
yes
HCAT_ECOLI
Q47142
hcaT

yfhS

b2536 JW2520
integral IM protein (SEC in IM), Probable 3-phenylpropionic acid transporter HcaT
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
FADE_ECOLI
Q47146
fadE

yafH

b0221 JW5020
integral IM protein (SEC in IM), Acyl-coenzyme A dehydrogenase FadE
Integral Inner Membrane
B
IM (predicted)
 
Integral Membrane Protein
 
SRP,TF
SEC
 
 
yes
yes
YAFL_ECOLI
Q47151
yafL
b0227 JW0217
periplasmic protein (SEC through IM), Probable endopeptidase YafL
Periplasmic
G
N/A
Cell membrane
Periplasmic
 
 
SEC
 
 
yes
yes
LFHA_ECOLI
Q47153
lfhA

fhiA

b0229 JW5811
integral IM protein (SEC in IM), Putative truncated export/assembly LfhA
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane
Integral Membrane Protein
 
SRP
SEC
 
 
yes
no
ARNE_ECOLI
Q47377
arnE

pmrL yfbW

b4544 JW2252
integral IM protein (SEC in IM), Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane; Multi-pass membrane protein
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
YAIO_ECOLI
Q47534
yaiO
b0358 JW0349
periplasmic protein (SEC through IM), YaiO
Periplasmic
G
N/A
Cell outer membrane
Periplasmic
 
 
SEC
 
 
no
yes
YAIP_ECOLI
Q47536
yaiP
b0363 JW0355
integral IM protein (SEC in IM), glycosyltransferase YaiP
Integral Inner Membrane
B
IM (predicted)
 
Integral Membrane Protein
 
SRP
SEC
 
 
no
yes
TAUA_ECOLI
Q47537
tauA

ssiA yaiR

b0365 JW0357
periplasmic protein (SEC through IM), Taurine-binding periplasmic TauA
Periplasmic
G
N/A
Periplasm
Periplasmic (Experimental)
 
 
SEC
 
 
no
yes
TAUC_ECOLI
Q47539
tauC

ssiC yaiJ

b0367 JW0359
integral IM protein (SEC in IM), Taurine transport system permease TauC
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane
Integral Membrane Protein
 
SRP
SEC
 
 
no
yes
SAPA_ECOLI
Q47622
sapA
b1294 JW1287
periplasmic protein (SEC through IM), Probable ABC transporter periplasmic-binding SapA
Periplasmic
G
N/A
Periplasm
Periplasmic (Experimental)
 
 
SEC
SURA
 
yes
yes
MMUP_ECOLI
Q47689
mmuP

ykfD

b0260 JW5027
integral IM protein (SEC in IM), Probable S-methylmethionine permease MmuP
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane
Integral Membrane Protein
 
SRP
SEC
 
 
yes
no
UIDC_ECOLI
Q47706
uidC

gusC

b1615 JW1607
OM b-barrel protein (SEC through IM, inserted in OM by BAM), Membrane-associated UidC UidC
Outer Membrane b-barrel protein
H
N/A
Cell outer membrane
Outer Membrane ??-barrel protein (Experimental)
 
 
SEC
 
BAM
no
yes
COPA_ECOLI
Q59385
copA

atcU f834 ybaR

b0484 JW0473
integral IM protein (SEC-YidC in IM), Copper-exporting P-type ATPase CopA
Integral Inner Membrane
B
IM (predicted), Detected in IM Fraction
Copper-exporting P-type ATPase: Cell inner membrane
Integral Membrane Protein (Experimental)
 
SRP
SEC-YidC
 
 
no
yes
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