STEPdb: Sub-cellular Topologies of E.coli Polypeptides.

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E.coli K-12 (MG1655) Exportome

(mouse over and click on the one letter topology symbols to see which proteins of this specific subproteome are localized in each location)

Bacterial cell cartoon of sub-cellular locations


Protein ID
(Uniprot)
Accession
(Uniprot)
Gene Name
(Uniprot)
Order
Locus Name
Protein Name
(STEPdb)
Full Name
Symbol
Uniprot
EchoLOCATION
Extracellular Appendage
First Level
Targeting
Chaperoning
First Level
Secretion
System
Second Level
Targeting
Chaperoning
Second Level
Secretion
System
K-12 Core
Proteome
(yes/no)
K-12 Basic
Proteome
(yes/no)
IBSD_ECOLI
C1P616
ibsD
b4664 JW3023.1
integral IM protein (SEC in IM), Small toxin IbsD
Integral Inner Membrane
B
N/A
Membrane
-
 
 
SEC
 
 
no
yes
PMRR_ECOLI
G3MTW7
pmrR
b4703 JW4072.1
integral IM protein (SEC in IM), Putative PmrR
Integral Inner Membrane
B
N/A
Cell inner membrane
-
 
 
SEC
 
 
no
 
YPDI_ECOLI
O32528
ypdI
b2376 JW2373
OM lipoprotein (SEC through IM, inserted in OM by LOL), YpdI
Outer Membrane Lipoprotein
I
N/A
Cell membrane
Outer membrane Lipoprotein
 
 
SEC
 
LOL
no
yes
YFJS_ECOLI
O52982
yfjS
b2636 JW5921
IM lipoprotein (SEC through IM, inserted in OM by LOL), YfjS
Inner Membrane Lipoprotein
E
N/A
Cell inner membrane
Inner membrane lipoprotein
 
 
SEC
 
LOL
no
no
GSPB_ECOLI
P03825
gspB

pinO pioO pno

b3322 JW3284
integral IM protein (SEC in IM), Putative general secretion pathway B GspB
Integral Inner Membrane
B
IM (predicted)
Cell membrane
Membrane anchored
 
SRP
SEC
 
 
no
yes
SODM_ECOLI
P00448
sodA
b3908 JW3879
periplasmic protein (SEC through IM), Superoxide dismutase SodA
Periplasmic
G
N/A
 
Cytoplasmic
 
 
SEC
 
 
yes
yes
PHSM_ECOLI
P00490
malP
b3417 JW5689
integral IM protein (SEC in IM), Maltodextrin phosphorylase MalP
Integral Inner Membrane
B
Soluble IM Fraction
 
Cytoplasmic
 
 
SEC
 
 
yes
yes
PTM3C_ECOLI
P00550
mtlA
b3599 JW3573
integral IM protein (SEC in IM), PTS system mannitol-specific EIICBA component MtlA
Integral Inner Membrane
B
IM (predicted), Detected in IM Fraction
Cell inner membrane
Integral Membrane Protein
 
SRP (exp)
SEC
 
 
yes
yes
YGDB_ECOLI
P08370
ygdB
b2824 JW5450
periplasmic protein (SEC through IM), YgdB
Periplasmic
G
N/A
 
Periplasmic
 
 
SEC
 
 
yes
yes
PPDB_ECOLI
P08371
ppdB

ygdC

b2825 JW5451
integral IM protein (SEC in IM), Prepilin peptidase-dependent B PpdB
Integral Inner Membrane
B
IM (predicted)
 
Membrane anchored
 
SRP
SEC
 
 
yes
yes
PPDC_ECOLI
P08372
ppdC

ygdA

b2823 JW2791
integral IM protein (SEC in IM), Prepilin peptidase-dependent C PpdC
Integral Inner Membrane
B
IM (predicted)
 
Membrane anchored
 
SRP
SEC
 
 
yes
yes
PPB_ECOLI
P00634
phoA
b0383 JW0374
periplasmic protein (SEC through IM), Alkaline phosphatase PhoA
Periplasmic
G
N/A
Periplasm
Periplasmic (Experimental)
 
 
SEC
DSBA
 
no
yes
LEP_ECOLI
P00803
lepB
b2568 JW2552
integral IM protein (SEC-YidC in IM), Signal peptidase I LepB
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane
Integral Membrane Protein
 
 
SEC-YidC
 
 
yes
yes
LSPA_ECOLI
P00804
lspA

lsp

b0027 JW0025
integral IM protein (SEC in IM), Signal peptidase II LspA
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
ASPG2_ECOLI
P00805
ansB
b2957 JW2924
periplasmic protein (SEC through IM), L-asparaginase 2 AnsB
Periplasmic
G
N/A
Periplasm
Periplasmic (Experimental)
 
 
SEC
 
 
yes
yes
FTSB_ECOLI
P0A6S5
ftsB

ygbQ

b2748 JW2718
integral IM protein (SEC in IM), Cell division FtsB
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane
Membrane anchored
 
SRP
SEC
 
 
yes
yes
PSIE_ECOLI
P0A7C8
psiE

yjbA

b4030 JW3990
integral IM protein (SEC in IM), PsiE
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane; Multi-pass membrane protein
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
YFBV_ECOLI
P0A8D9
yfbV
b2295 JW2292
integral IM protein (SEC in IM), UPF0208 YfbV
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane; Multi-pass membrane protein
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
AMPC_ECOLI
P00811
ampC

ampA

b4150 JW4111
periplasmic protein (SEC through IM), Beta-lactamase AmpC
Periplasmic
G
N/A
Periplasm
Periplasmic (Experimental)
 
 
SEC
 
 
yes
yes
MALF_ECOLI
P02916
malF
b4033 JW3993
integral IM protein (SEC in IM), Maltose/maltodextrin transport system permease MalF
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane
Integral Membrane Protein
 
SRP (exp)
SEC
YfgM
 
no
yes
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