STEPdb: Sub-cellular Topologies of E.coli Polypeptides.

View: E.coli K-12 (MG1655) Exportome  Export to Excel  Export to HTML  Export to XML  Export to CSV  

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E.coli K-12 (MG1655) Exportome

(mouse over and click on the one letter topology symbols to see which proteins of this specific subproteome are localized in each location)

Bacterial cell cartoon of sub-cellular locations


Protein ID
(Uniprot)
Accession
(Uniprot)
Gene Name
(Uniprot)
Order
Locus Name
Protein Name
(Uniprot)
Full Name
Symbol
Uniprot
EchoLOCATION
Extracellular Appendage
First Level
Targeting
Chaperoning
First Level
Secretion
System
Second Level
Targeting
Chaperoning
Second Level
Secretion
System
K-12 Core
Proteome
(yes/no)
K-12 Basic
Proteome
(yes/no)
MALF_ECOLI
P02916
malF
b4033 JW3993
Maltose transport system permease protein malF
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane | Multi-pass membrane protein | Periplasmic side
Integral Membrane Protein
 
SRP (exp)
SEC
YfgM
 
no
yes
PBPA_ECOLI
P02918
mrcA

ponA

b3396 JW3359
Penicillin-binding protein 1A (PBP-1a) (PBP1a) [Includes: Penicillin-insensitive transglycosylase (EC 2.4.2.-) (Peptidoglycan TGase); Penicillin-sensitive transpeptidase (EC 3.4.-.-) (DD-transpeptidase)]
Integral Inner Membrane
B
Soluble IM Fraction
Cell inner membrane | Single-pass type II membrane protein
Membrane anchored (Experimental)
 
SRP
SEC
 
 
yes
yes
RNFA_ECOLI
P0A766
rnfA

ydgL

b1627 JW1619
Electron transport complex protein rnfA
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane | Multi-pass membrane protein
Integral Membrane Protein(experimental)
 
SRP
SEC
 
 
yes
yes
PSIE_ECOLI
P0A7C8
psiE

yjbA

b4030 JW3990
Protein psiE
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane | Multi-pass membrane protein
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
TATE_ECOLI
P0A843
tatE

ybeC

b0627 JW0622
Sec-independent protein translocase protein tatE
Integral Inner Membrane
B
IM (predicted), Detected in IM Fraction
Cell inner membrane | Single-pass membrane protein
Membrane anchored
 
SRP
SEC
 
 
yes
yes
PBPB_ECOLI
P02919
mrcB

pbpF ponB

b0149 JW0145
Penicillin-binding protein 1B (PBP-1b) (PBP1b) (Murein polymerase) [Includes: Penicillin-insensitive transglycosylase (EC 2.4.1.129) (Peptidoglycan TGase) (Peptidoglycan glycosyltransferase); Penicillin-sensitive transpeptidase (EC 3.4.-.-) (DD-transpepti
Integral Inner Membrane
B
IM (predicted), Detected in IM Fraction
Cell inner membrane | Single-pass type II membrane protein
Membrane anchored
 
SRP
SEC
 
 
yes
yes
LACY_ECOLI
P02920
lacY
b0343 JW0334
Lactose permease (Lactose-proton symport)
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane | Multi-pass membrane protein
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
MELB_ECOLI
P02921
melB

mel-4

b4120 JW4081
Melibiose carrier protein (Melibiose permease) (Melibiose transporter) (Na+ (Li+)/melibiose symporter) (Thiomethylgalactoside permease II)
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane | Multi-pass membrane protein
Integral Membrane Protein
 
SRP
SEC
 
 
no
yes
YFBV_ECOLI
P0A8D9
yfbV
b2295 JW2292
UPF0208 membrane protein yfbV
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane | Multi-pass membrane protein
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
USPB_ECOLI
P0A8S5
uspB

yhiO

b3494 JW3461
Universal stress protein B
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane | Multi-pass membrane protein
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
FLIE_ECOLI
P0A8T5
fliE

fla AI flaN

b1937 JW1921
Flagellar hook-basal body complex protein fliE
Peripheral inner membrane protein facing the periplasm
F2
N/A
Bacterial flagellum basal body
Cytoplasmic
flagellum
 
Flagellum
 
 
no
yes
ARAF_ECOLI
P02924
araF
b1901 JW1889
L-arabinose-binding periplasmic protein (ABP)
Periplasmic
G
N/A
Periplasm
Periplasmic (Experimental)
 
 
SEC
 
 
yes
yes
RBSB_ECOLI
P02925
rbsB

prlB rbsP

b3751 JW3730
D-ribose-binding periplasmic protein
Periplasmic
G
Soluble IM Fraction
Periplasm
Periplasmic (Experimental)
 
 
SEC
SKP
 
no
yes
TONB_ECOLI
P02929
tonB

exbA

b1252 JW5195
Protein tonB
Integral Inner Membrane
B
N/A
Cell inner membrane | Single-pass membrane protein | Periplasmic side
Membrane anchored
 
 
SEC
 
 
yes
yes
TOLC_ECOLI
P02930
tolC

mtcB mukA refI

b3035 JW5503
Outer membrane protein tolC
Outer Membrane b-barrel protein
H
Soluble IM Fraction
Cell outer membrane | Multi-pass membrane protein
Outer Membrane β-barrel protein (Experimental)
 
SECB
SEC
SKP
BAM
yes
yes
YCCT_ECOLI
P0A8X4
yccT
b0964 JW0947
UPF0319 protein yccT
Periplasmic
G
N/A
 
Periplasmic
 
 
SEC
 
 
yes
yes
ESSD_ECOLI
P0A9R2
essD

ybcR

b0554 JW0543
Lysis protein S homolog from lambdoid prophage DLP12
Integral Inner Membrane
B
IM (predicted)
 
Integral Membrane Protein
 
SRP
SEC
 
 
yes
no
YOBA_ECOLI
P0AA57
yobA
b1841 JW1830
Protein yobA
Periplasmic
G
N/A
Periplasm
Periplasmic
 
 
SEC
 
 
yes
yes
OMPF_ECOLI
P02931
ompF

cmlB coa cry tolF

b0929 JW0912
Outer membrane protein F (Outer membrane protein 1A) (Outer membrane protein B) (Outer membrane protein IA) (Porin OmpF)
Outer Membrane b-barrel protein
H
Soluble IM Fraction
Cell outer membrane | Multi-pass membrane protein
Outer Membrane β-barrel protein (Experimental)
 
TF
SEC
SKP,SURA
BAM
yes
yes
PHOE_ECOLI
P02932
phoE

ompE

b0241 JW0231
Outer membrane pore protein E
Outer Membrane b-barrel protein
H
N/A
Cell outer membrane | Multi-pass membrane protein
Outer Membrane β-barrel protein (Experimental)
 
 
SEC
 
BAM
yes
yes
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