STEPdb: Sub-cellular Topologies of E.coli Polypeptides.

View: E.coli K-12 (MG1655) Exportome  Export to Excel  Export to HTML  Export to XML  Export to CSV  

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E.coli K-12 (MG1655) Exportome

(mouse over and click on the one letter topology symbols to see which proteins of this specific subproteome are localized in each location)

Bacterial cell cartoon of sub-cellular locations


Protein ID
(Uniprot)
Accession
(Uniprot)
Gene Name
(Uniprot)
Order
Locus Name
Protein Name
(Uniprot)
Full Name
Symbol
Uniprot
EchoLOCATION
Extracellular Appendage
First Level
Targeting
Chaperoning
First Level
Secretion
System
Second Level
Targeting
Chaperoning
Second Level
Secretion
System
K-12 Core
Proteome
(yes/no)
K-12 Basic
Proteome
(yes/no)
NLPA_ECOLI
P04846
nlpA
b3661 JW3635
Lipoprotein 28
Inner Membrane Lipoprotein
E
Soluble IM Fraction
Cell inner membrane | Lipid-anchor
Inner membrane lipoprotein
 
 
SEC
 
LOL
yes
yes
FLIC_ECOLI
P04949
fliC

flaF hag

b1923 JW1908
Flagellin
Peripheral outer membrane protein facing the extra-cellular space
F4
Soluble IM Fraction
SecretedBacterial flagellum
Cell surface appendage (Experimental)
flagellum
 
Flagellum
 
Fla
no
yes
PTRA_ECOLI
P05458
ptrA

ptr

b2821 JW2789
Protease 3 (EC 3.4.24.55) (Pitrilysin) (Protease III) (Protease pi)
Periplasmic
G
N/A
Periplasm
Periplasmic(experimental)
 
 
SEC
SURA
 
yes
yes
MCP3_ECOLI
P05704
trg
b1421 JW1417
Methyl-accepting chemotaxis protein III (MCP-III) (Ribose and galactose chemoreceptor protein)
Integral Inner Membrane
B
IM (predicted), Detected in IM Fraction
Cell inner membrane | Multi-pass membrane protein
Integral Membrane Protein
 
SRP
SEC
 
 
no
yes
YBFB_ECOLI
P0AAU5
ybfB
b0702 JW0691
Uncharacterized protein ybfB
Integral Inner Membrane
B
IM (predicted)
Cell membrane | Multi-pass membrane protein
Integral Membrane Protein
 
SRP
SEC
 
 
no
yes
YBGE_ECOLI
P0AAV0
ybgE
b0735 JW0725
Uncharacterized protein ybgE
Integral Inner Membrane
B
IM (predicted)
 
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
FEPA_ECOLI
P05825
fepA

fep feuB

b0584 JW5086
Ferrienterobactin receptor (Enterobactin outer-membrane receptor)
Outer Membrane b-barrel protein
H
N/A
Cell outer membrane | Multi-pass membrane protein
Outer Membrane β-barrel protein (Experimental)
 
 
SEC
SKP
BAM
yes
yes
BTUB_ECOLI
P06129
btuB

bfe cer dcrC

b3966 JW3938
Uncharacterized protein yhcF
Outer Membrane b-barrel protein
H
N/A
Cell outer membrane | Multi-pass membrane protein
Outer Membrane β-barrel protein (Experimental)
 
 
SEC
SKP
BAM
no
yes
FTSQ_ECOLI
P06136
ftsQ
b0093 JW0091
Cell division protein ftsQ
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane | Single-pass type II membrane protein
Membrane anchored
 
SRP
SEC
 
 
yes
yes
YBGS_ECOLI
P0AAV6
ybgS
b0753 JW0736
Uncharacterized protein ybgS
Periplasmic
G
N/A
 
Periplasmic
 
 
SEC
 
 
yes
yes
YBHQ_ECOLI
P0AAW5
ybhQ
b0791 JW0774
Inner membrane protein ybhQ
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane | Multi-pass membrane protein
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
YBHT_ECOLI
P0AAW9
ybhT
b0762 JW5102
Bacteriophage N4 adsorption protein B
Integral Inner Membrane
B
IM (predicted)
Membrane | Single-pass membrane protein
Membrane anchored
 
SRP
YidC
 
 
no
yes
CDH_ECOLI
P06282
cdh
b3918 JW3889
CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26) (CDP-diacylglycerol phosphatidylhydrolase) (CDP-diglyceride hydrolase)
Periplasmic
G
Soluble IM Fraction
Cell inner membrane | Single-pass membrane protein
Membrane anchored
 
 
SEC
 
 
yes
yes
BTUC_ECOLI
P06609
btuC
b1711 JW1701
Vitamin B12 import system permease protein BtuC
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane | Multi-pass membrane protein
Integral Membrane Protein
 
SRP
YidC
 
 
yes
yes
BIRA_ECOLI
P06709
birA

bioR dhbB

b3973 JW3941
Bifunctional protein BirA [Includes: Biotin operon repressor; Biotin--[acetyl-CoA-carboxylase] synthetase (EC 6.3.4.15) (Biotin--protein ligase)]. Deletion of BioR resulted in a 15-fold increase of bio operon transcription in the presence of high biotin levels.
Nucleoid, Integral Inner Membrane
N, B
IM (predicted)
 
Cytoplasmic
 
SRP
SEC
 
 
yes
yes
FHUA_ECOLI
P06971
fhuA

tonA

b0150 JW0146
Uncharacterized protein yohN
Outer Membrane b-barrel protein
H
N/A
Cell outer membrane | Multi-pass membrane protein
Outer Membrane β-barrel protein (Experimental)
 
SECB
SEC
SURA,SKP
BAM
yes
yes
YBIJ_ECOLI
P0AAX3
ybiJ
b0802 JW0787
Uncharacterized protein ybiJ
Periplasmic
G
N/A
Periplasm
Periplasmic
 
 
SEC
 
 
yes
yes
MCBA_ECOLI
P0AAX6
mcbA

ybiM

b0806 JW5106
Uncharacterized protein mcbA (MqsR-controlled colanic acid and biofilm protein A)
Periplasmic
G
N/A
Periplasm
Periplasmic
 
 
SEC
 
 
yes
yes
YBJH_ECOLI
P0AAY4
ybjH
b0843 JW0827
Uncharacterized protein ybjH
Periplasmic
G
N/A
 
Periplasmic
 
 
SEC
 
 
yes
yes
FHUB_ECOLI
P06972
fhuB
b0153 JW0149
Iron(3+)-hydroxamate import system permease protein fhuB (Ferric hydroxamate uptake protein B) (Ferrichrome transport system permease protein fhuB) (Ferrichrome uptake protein fhuB) (Iron(III)-hydroxamate import system permease protein fhuB)
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane | Multi-pass membrane protein
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
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