STEPdb: Sub-cellular Topologies of E.coli Polypeptides.

View: E. coli K-12 / MG1655/ ATCC 47076 proteome  Export to Excel  Export to HTML  Export to XML  Export to CSV  

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E. coli K-12 / MG1655/ ATCC 47076 proteome

(mouse over and click on the one letter topology symbols to see which proteins of this specific subproteome are localized in each location)

Bacterial cell cartoon of sub-cellular locations


Protein ID
(Uniprot)
Accession
(Uniprot)
Gene Name
(Uniprot)
Order
Locus Name
Protein Name
(STEPdb)
Full Name
Symbol
Uniprot
EchoLOCATION
Extracellular Appendage
First Level
Targeting
Chaperoning
First Level
Secretion
System
Second Level
Targeting
Chaperoning
Second Level
Secretion
System
K-12 Core
Proteome
(yes/no)
K-12 Basic
Proteome
(yes/no)
CSGF_ECOLI
P0AE98
csgF
b1038 JW1021
Curli related extra-cellular peripheral OM protein (SEC through IM), secreted over OM by curli), Curli production assembly/transport component CsgF
Peripheral outer membrane protein facing the extra-cellular space
F4
Cell outer membrane
Periplasmic (Experimental)
N/A
Curli
 
SEC
 
Curli
yes
yes
CSGA_ECOLI
P28307
csgA
b1042 JW1025
Curli related extra-cellular peripheral OM protein (SEC through IM), secreted over OM by curli), Major curlin subunit CsgA
Peripheral outer membrane protein facing the extra-cellular space
F4
Fimbrium
Cell surface appendage (Experimental)
N/A
Curli
 
SEC
 
Curli
yes
yes
CSGB_ECOLI
P0ABK7
csgB
b1041 JW1024
Curli related extra-cellular peripheral OM protein (SEC through IM), secreted over OM by curli), Minor curlin subunit CsgB
Peripheral outer membrane protein facing the extra-cellular space
F4
Fimbrium
Cell surface appendage (Experimental)
N/A
Curli
 
SEC
 
Curli
yes
yes
CSGG_ECOLI
P0AEA2
csgG
b1037 JW1020
Curli related OM lipoprotein & extra-cellular peripheral OM protein (SEC through IM), inserted in OM by LOL), Curli production assembly/transport component CsgG
Outer Membrane Lipoprotein, Peripheral outer membrane protein facing the extra-cellular space
I, F4
Cell membrane
Outer membrane Lipoprotein (Experimental)
N/A
Curli
 
SEC
 
LOL: Localization Of Lipoproteins
yes
yes
CSGE_ECOLI
P0AE95
csgE
b1039 JW1022
Curli related periplasmic protein (SEC through IM), Curli production assembly/transport component CsgE
Periplasmic
G
 
Periplasmic (Experimental)
N/A
Curli
 
SEC
SurA
 
yes
yes
SECM_ECOLI
P62395
secM

srrA yacA

b0097 JW5007
cytoplasmic & periplasmic protein (SEC through IM), Secretion monitor SecM
Cytoplasmic, Periplasmic
A, G
Cytoplasm; cytosol
Periplasmic (Experimental)
N/A
 
 
SEC
SurA
 
yes
yes
YGFZ_ECOLI
P0ADE8
ygfZ

yzzW

b2898 JW2866
cytoplasmic & periplasmic protein (SEC through IM), tRNA-modifying YgfZ
Cytoplasmic, Periplasmic
A, G
Cytoplasm
Cytoplasmic (Experimental)
N/A
 
 
SEC
 
 
yes
yes
PMBA_ECOLI
P0AFK0
pmbA

tldE

b4235 JW4194
cytoplasmic metalloprotease PmbA
Cytoplasmic
A
Cytoplasm
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
TLDD_ECOLI
P0AGG8
tldD

yhdO

b3244 JW3213
cytoplasmic metalloprotease TldD
Cytoplasmic
A
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
ARCA_ECOLI
P0A9Q1
arcA

cpxC dye fexA msp seg sfrA

b4401 JW4364
cytoplasmic nucleoid peripheral IM protein, Aerobic respiration control ArcA
Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm
A, N, F1
Cytoplasm
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
SYA_ECOLI
P00957
alaS

lovB

b2697 JW2667
cytoplasmic nucleoid peripheral IM protein, Alanine--tRNA ligase AlaS
Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm
A, N, F1
Cytoplasm
Cytoplasmic
N/A
 
TF
 
 
 
no
yes
RHLB_ECOLI
P0A8J8
rhlB

mmrA

b3780 JW3753
cytoplasmic nucleoid peripheral IM protein, ATP-dependent RNA helicase RhlB
Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm
A, N, F1
Cytoplasm
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
PUTA_ECOLI
P09546
putA

poaA

b1014 JW0999
cytoplasmic nucleoid peripheral IM protein, Bifunctional PutA
Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm
A, N, F1
 
Cytoplasmic
Soluble protein detected in Inner Membrane Fraction
 
 
 
 
 
yes
yes
CRP_ECOLI
P0ACJ8
crp

cap csm

b3357 JW5702
cytoplasmic nucleoid peripheral IM protein, cAMP-activated global transcriptional regulator Crp
Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm
A, N, F1
 
Cytoplasmic
N/A
 
TF
 
 
 
yes
yes
DNAA_ECOLI
P03004
dnaA
b3702 JW3679
cytoplasmic nucleoid peripheral IM protein, Chromosomal replication initiator DnaA
Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm
A, N, F1
Cytoplasm
Cytoplasmic
N/A
 
 
 
 
 
no
yes
MUKB_ECOLI
P22523
mukB
b0924 JW0907
cytoplasmic nucleoid peripheral IM protein, Chromosome partition MukB
Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm
A, N, F1
Cytoplasm; nucleoid
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
MUKE_ECOLI
P22524
mukE

kicA ycbA

b0923 JW0906
cytoplasmic nucleoid peripheral IM protein, Chromosome partition MukE
Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm
A, N, F1
Cytoplasm; nucleoid
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
MUKF_ECOLI
P60293
mukF

kicB

b0922 JW0905
cytoplasmic nucleoid peripheral IM protein, Chromosome partition MukF
Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm
A, N, F1
Cytoplasm; nucleoid
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
CSGD_ECOLI
P52106
csgD
b1040 JW1023
cytoplasmic nucleoid peripheral IM protein, CsgBAC operon transcriptional regulatory protein CsgD
Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm
A, N, F1
Cell inner membrane
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
GYRA_ECOLI
P0AES4
gyrA

hisW nalA parD

b2231 JW2225
cytoplasmic nucleoid peripheral IM protein, DNA gyrase subunit A GyrA
Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm
A, N, F1
Cytoplasm
Cytoplasmic
N/A
 
TF
 
 
 
yes
yes
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