STEPdb: Sub-cellular Topologies of E.coli Polypeptides.

View: E. coli K-12 / MG1655/ ATCC 47076 proteome  Export to Excel  Export to HTML  Export to XML  Export to CSV  

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E. coli K-12 / MG1655/ ATCC 47076 proteome

(mouse over and click on the one letter topology symbols to see which proteins of this specific subproteome are localized in each location)

Bacterial cell cartoon of sub-cellular locations


Protein ID
(Uniprot)
Accession
(Uniprot)
Gene Name
(Uniprot)
Order
Locus Name
Protein Name
(Uniprot)
Full Name
Symbol
Uniprot
EchoLOCATION
Extracellular Appendage
First Level
Targeting
Chaperoning
First Level
Secretion
System
Second Level
Targeting
Chaperoning
Second Level
Secretion
System
K-12 Core
Proteome
(yes/no)
K-12 Basic
Proteome
(yes/no)
RF3_ECOLI
P0A7I4
prfC

miaD tos

b4375 JW5873
Peptide chain release factor 3 (RF-3)
Cytoplasmic
A
Cytoplasm
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
DEF_ECOLI
P0A6K3
def

fms

b3287 JW3248
Peptide deformylase (PDF) (EC 3.5.1.88) (Polypeptide deformylase)
Peripheral inner membrane protein facing the cytoplasm
F1
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
MSRA_ECOLI
P0A744
msrA

pms

b4219 JW4178
Peptide methionine sulfoxide reductase msrA (Protein-methionine-S-oxide reductase) (EC 1.8.4.11) (Peptide-methionine (S)-S-oxide reductase) (Peptide Met(O) reductase)
Cytoplasmic
A
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
MSRB_ECOLI
P0A746
msrB

yeaA

b1778 JW1767
Peptide methionine sulfoxide reductase msrB (EC 1.8.4.12) (Peptide-methionine (R)-S-oxide reductase)
Cytoplasmic
A
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
SAPA_ECOLI
Q47622
sapA
b1294 JW1287
Peptide transport periplasmic protein sapA
Periplasmic
G
Secreted
Periplasmic (Experimental)
N/A
 
 
SEC
SurA
 
yes
yes
SAPD_ECOLI
P0AAH4
sapD
b1291 JW1284
Peptide transport system ATP-binding protein sapD
Peripheral inner membrane protein facing the cytoplasm
F1
Cell inner membrane | Peripheral membrane protein
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
SAPF_ECOLI
P0AAH8
sapF
b1290 JW1283
Peptide transport system ATP-binding protein sapF
Peripheral inner membrane protein facing the cytoplasm
F1
Cell inner membrane | Peripheral membrane protein
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
SAPB_ECOLI
P0AGH3
sapB
b1293 JW1286
Peptide transport system permease protein sapB
Integral Inner Membrane
B
Cell inner membrane | Multi-pass membrane protein
Integral Membrane Protein
IM (predicted)
 
SRP
SEC
 
 
yes
yes
SAPC_ECOLI
P0AGH5
sapC
b1292 JW1285
Peptide transport system permease protein sapC
Integral Inner Membrane
B
Cell inner membrane | Multi-pass membrane protein
Integral Membrane Protein
IM (predicted)
 
SRP
SEC
 
 
yes
yes
FLGJ_ECOLI
P75942
flgJ

fla FX flaZ

b1081 JW1068
Peptidoglycan hydrolase flgJ (EC 3.2.1.-) (Muramidase flgJ)
Cytoplasmic
A
Secreted
Cytoplasmic
N/A
 
 
Flagellum
 
 
yes
yes
FTSI_ECOLI
P0AD68
ftsI

pbpB

b0084 JW0082
Peptidoglycan synthase ftsI (EC 2.4.1.129) (Penicillin-binding protein 3) (PBP-3) (Peptidoglycan glycosyltransferase 3)
Integral Inner Membrane
B
Cell inner membrane | Single-pass membrane protein | Periplasmic side
Membrane anchored
Soluble protein detected in Inner Membrane Fraction
 
SRP
SEC
 
 
yes
yes
PAL_ECOLI
P0A912
pal

excC

b0741 JW0731
Peptidoglycan-associated lipoprotein
Outer Membrane Lipoprotein
I
Cell outer membrane | Lipid-anchor
Outer membrane Lipoprotein (Experimental)
Soluble protein detected in Inner Membrane Fraction
 
 
SEC
 
LOL: Localization Of Lipoproteins
yes
yes
DCP_ECOLI
P24171
dcp
b1538 JW1531
Peptidyl-dipeptidase dcp (EC 3.4.15.5) (Dipeptidyl carboxypeptidase)
Cytoplasmic
A
Cytoplasm
Cytoplasmic
N/A
 
 
 
 
 
no
yes
PPIA_ECOLI
P0AFL3
ppiA

rot rotA

b3363 JW3326
Peptidyl-prolyl cis-trans isomerase A (PPIase A) (EC 5.2.1.8) (Cyclophilin A) (Rotamase A)
Periplasmic
G
Secreted
Periplasmic (Experimental)
N/A
 
 
SEC
 
 
yes
yes
PPIB_ECOLI
P23869
ppiB
b0525 JW0514
Peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (Rotamase B)
Peripheral inner membrane protein facing the cytoplasm
F1
Cytoplasm
Cytoplasmic (Experimental)
N/A
 
 
 
 
 
yes
yes
PPIC_ECOLI
P0A9L5
ppiC

parVA

b3775 JW3748
Peptidyl-prolyl cis-trans isomerase C (PPIase C) (EC 5.2.1.8) (Par10) (Parvulin) (Rotamase C)
Cytoplasmic
A
Cytoplasm
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
PPID_ECOLI
P0ADY1
ppiD

ybaU

b0441 JW0431
Peptidyl-prolyl cis-trans isomerase D (PPIase D) (EC 5.2.1.8) (Rotamase D)
Integral Inner Membrane
B
Cell inner membrane | Single-pass type II membrane protein | Periplasmic side
Membrane anchored (Experimental)
IM (predicted), Detected in IM Fraction
 
SRP
SEC
 
 
yes
yes
PTH_ECOLI
P0A7D1
pth
b1204 JW1195
Peptidyl-tRNA hydrolase (PTH) (EC 3.1.1.29)
Cytoplasmic
A
Cytoplasm
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
ARFB_ECOLI
P40711
arfB

yaeJ

b0191 JW0187
Peptidyl-tRNA hydrolase ArfB
Cytoplasmic, ribosomal
A, r
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
PPA_ECOLI
P07102
appA
b0980 JW0963
Periplasmic AppA protein [Includes: Phosphoanhydride phosphohydrolase (EC 3.1.3.2) (pH 2.5 acid phosphatase) (AP); 4-phytase (EC 3.1.3.26)]
Periplasmic
G
Secreted
Periplasmic (Experimental)
N/A
 
 
SEC
DsbC
 
yes
yes
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