STEPdb: Sub-cellular Topologies of E.coli Polypeptides.

View: E. coli K-12 / MG1655/ ATCC 47076 proteome  Export to Excel  Export to HTML  Export to XML  Export to CSV  

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E. coli K-12 / MG1655/ ATCC 47076 proteome

(mouse over and click on the one letter topology symbols to see which proteins of this specific subproteome are localized in each location)

Bacterial cell cartoon of sub-cellular locations


Protein ID
(Uniprot)
Accession
(Uniprot)
Gene Name
(Uniprot)
Order
Locus Name
Protein Name
(Uniprot)
Full Name
Symbol
Uniprot
EchoLOCATION
Extracellular Appendage
First Level
Targeting
Chaperoning
First Level
Secretion
System
Second Level
Targeting
Chaperoning
Second Level
Secretion
System
K-12 Core
Proteome
(yes/no)
K-12 Basic
Proteome
(yes/no)
YIAM_ECOLI
P37674
yiaM
b3577 JW3549
2,3-diketo-L-gulonate TRAP transporter small permease protein yiaM
Integral Inner Membrane
B
Cell inner membrane | Multi-pass membrane protein
Integral Membrane Protein
IM (predicted)
 
SRP
SEC
 
 
no
yes
YIAO_ECOLI
P37676
yiaO
b3579 JW3551
2,3-diketo-L-gulonate-binding periplasmic protein yiaO (2,3-DKG-binding protein) (Extracytoplasmic solute receptor protein yiaO)
Periplasmic
G
Secreted
Periplasmic
N/A
 
 
SEC
 
 
no
yes
FADH_ECOLI
P42593
fadH

ygjL

b3081 JW3052
2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34) (2,4-dienoyl coenzyme A reductase)
Cytoplasmic
A
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
DKGA_ECOLI
Q46857
dkgA

yqhE

b3012 JW5499
2,5-diketo-D-gluconic acid reductase A (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (EC 1.1.1.274) (AKR5C)
Cytoplasmic
A
Cytoplasm
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
DKGB_ECOLI
P30863
dkgB

yafB

b0207 JW0197
2,5-diketo-D-gluconic acid reductase B (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (EC 1.1.1.274) (AKR5D)
Cytoplasmic
A
Cytoplasm
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
CITG_ECOLI
P77231
citG

ybdT

b0613 JW0605
2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase (2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase) (EC 2.7.8.25)
Cytoplasmic
A
 
Cytoplasmic
IM (predicted)
 
 
 
 
 
yes
yes
KBL_ECOLI
P0AB77
kbl
b3617 JW3592
2-amino-3-ketobutyrate coenzyme A ligase (AKB ligase) (EC 2.3.1.29) (Glycine acetyltransferase)
Peripheral inner membrane protein facing the cytoplasm
F1
 
Cytoplasmic
N/A
 
TF
 
 
 
yes
yes
HPPK_ECOLI
P26281
folK
b0142 JW0138
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) (6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase) (PPPK) (7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase) (HPPK)
Cytoplasmic
A
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
ISPF_ECOLI
P62617
ispF

mecS ygbB

b2746 JW2716
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (MECDP-synthase) (MECPS) (EC 4.6.1.12)
Cytoplasmic
A
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
ISPD_ECOLI
Q46893
ispD

ygbP

b2747 JW2717
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (EC 2.7.7.60) (4-diphosphocytidyl-2C-methyl-D-erythritol synthase) (CDP-ME synthase) (MEP cytidylyltransferase) (MCT)
Cytoplasmic
A
 
Cytoplasmic
N/A
 
TF
 
 
 
yes
yes
DGOA_ECOLI
Q6BF16
dgoA

yidU

b4477 JW5628
2-dehydro-3-deoxy-6-phosphogalactonate aldolase (EC 4.1.2.21) (2-oxo-3-deoxygalactonate 6-phosphate aldolase) (6-phospho-2-dehydro-3-deoxygalactonate aldolase)
Cytoplasmic
A
 
Cytoplasmic
N/A
 
 
 
 
 
no
yes
KDUD_ECOLI
P37769
kduD

ygeC yqeD

b2842 JW2810
2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase (EC 1.1.1.127) (2-keto-3-deoxygluconate 5-dehydrogenase) (2-keto-3-deoxygluconate oxidoreductase) (KDG oxidoreductase)
Cytoplasmic
A
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
DGOK_ECOLI
P31459
dgoK

yidV

b3693 JW3670
2-dehydro-3-deoxygalactonokinase (EC 2.7.1.58) (2-keto-3-deoxy-galactonokinase) (2-oxo-3-deoxygalactonate kinase)
Cytoplasmic
A
 
Cytoplasmic
IM (predicted)
 
 
 
 
 
no
yes
KDGK_ECOLI
P37647
kdgK

yhjI

b3526 JW5668
2-dehydro-3-deoxygluconokinase (EC 2.7.1.45) (2-keto-3-deoxygluconokinase) (3-deoxy-2-oxo-D-gluconate kinase) (KDG kinase)
Cytoplasmic
A
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
KDSA_ECOLI
P0A715
kdsA
b1215 JW1206
2-dehydro-3-deoxyphosphooctonate aldolase (EC 2.5.1.55) (3-deoxy-D-manno-octulosonic acid 8-phosphate synthase) (KDO-8-phosphate synthase) (KDO 8-P synthase) (KDOPS) (Phospho-2-dehydro-3-deoxyoctonate aldolase)
Cytoplasmic
A
Cytoplasm
Cytoplasmic
IM (predicted)
 
 
 
 
 
yes
yes
PANE_ECOLI
P0A9J4
panE

apbA

b0425 JW0415
2-dehydropantoate 2-reductase (EC 1.1.1.169) (Ketopantoate reductase) (KPA reductase) (KPR)
Outer Membrane Lipoprotein
I
Cytoplasm
Cytoplasmic (Experimental)
IM (predicted)
 
 
SEC
 
LOL: Localization Of Lipoproteins
yes
yes
GARR_ECOLI
P0ABQ2
garR

yhaE

b3125 JW5526
2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60) (Tartronate semialdehyde reductase) (TSAR)
Cytoplasmic
A
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
GLXR_ECOLI
P77161
glxR

glxB1 ybbQ

b0509 JW0497
2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60) (Tartronate semialdehyde reductase) (TSAR)
Cytoplasmic
A
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
MHPC_ECOLI
P77044
mhpC
b0349 JW0340
2-hydroxy-6-oxononadienedioate/2-hydroxy-6-oxononatrienedioate hydrolase (EC 3.7.1.n1) (2-hydroxy-6-ketonona-2,4-diene-1,9-dioic acid 5,6-hydrolase) (2-hydroxy-6-oxonona-2,4,7-triene-1,9-dioic acid 5,6-hydrolase) (2-hydroxy-6-oxonona-2,4-diene-1,9-dioic a
Cytoplasmic
A
 
Cytoplasmic
N/A
 
 
 
 
 
no
yes
LEU1_ECOLI
P09151
leuA
b0074 JW0073
2-isopropylmalate synthase (EC 2.3.3.13) (Alpha-IPM synthase) (Alpha-isopropylmalate synthase)
Cytoplasmic
A
 
Cytoplasmic
N/A
 
 
 
 
 
no
yes
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