STEPdb: Sub-cellular Topologies of E.coli Polypeptides.

View: E. coli K-12 / MG1655/ ATCC 47076 proteome  Export to Excel  Export to HTML  Export to XML  Export to CSV  

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E. coli K-12 / MG1655/ ATCC 47076 proteome

(mouse over and click on the one letter topology symbols to see which proteins of this specific subproteome are localized in each location)

Bacterial cell cartoon of sub-cellular locations


Protein ID
(Uniprot)
Accession
(Uniprot)
Gene Name
(Uniprot)
Order
Locus Name
Protein Name
(Uniprot)
Full Name
Symbol
Uniprot
EchoLOCATION
Extracellular Appendage
First Level
Targeting
Chaperoning
First Level
Secretion
System
Second Level
Targeting
Chaperoning
Second Level
Secretion
System
K-12 Core
Proteome
(yes/no)
K-12 Basic
Proteome
(yes/no)
ASLA_ECOLI
P25549
aslA

atsA

b3801 JW3773
Arylsulfatase (AS) (EC 3.1.6.1) (Aryl-sulfate sulphohydrolase)
Periplasmic
G
Secreted
Periplasmic
N/A
 
 
SEC
 
 
no
yes
ULAA_ECOLI
P39301
ulaA

sgaT yjfS

b4193 JW5744
Ascorbate-specific permease IIC component ulaA (Ascorbate-specific PTS system EIIC component)
Integral Inner Membrane
B
Cell inner membrane | Multi-pass membrane protein
Integral Membrane Protein
IM (predicted)
 
SRP
SEC
 
 
yes
yes
ULAC_ECOLI
P69820
ulaC

ptxA sgaA yjfU

b4195 JW4153
Ascorbate-specific phosphotransferase enzyme IIA component (EC 2.7.1.-) (PTS system ascorbate-specific EIIA component)
Peripheral inner membrane protein facing the cytoplasm
F1
Cytoplasm
Cytoplasmic
N/A
 
 
 
 
 
no
yes
ULAB_ECOLI
P69822
ulaB

sgaB yjfT

b4194 JW4152
Ascorbate-specific phosphotransferase enzyme IIB component (EC 2.7.1.69) (Ascorbate-specific PTS system EIIB component)
Peripheral inner membrane protein facing the cytoplasm
F1
Cytoplasm
Cytoplasmic
N/A
 
 
 
 
 
no
yes
ASNB_ECOLI
P22106
asnB
b0674 JW0660
Asparagine synthetase B [glutamine-hydrolyzing] (EC 6.3.5.4)
Peripheral inner membrane protein facing the cytoplasm
F1
 
Cytoplasmic
N/A
 
TF
 
 
 
yes
yes
SYN_ECOLI
P0A8M0
asnS

tss

b0930 JW0913
Asparaginyl-tRNA synthetase (EC 6.1.1.22) (Asparagine--tRNA ligase) (AsnRS)
Peripheral inner membrane protein facing the cytoplasm
F1
Cytoplasm
Cytoplasmic
N/A
 
TF
 
 
 
yes
yes
PAND_ECOLI
P0A790
panD
b0131 JW0127
Aspartate 1-decarboxylase (EC 4.1.1.11) (Aspartate alpha-decarboxylase) [Cleaved into: Aspartate 1-decarboxylase beta chain; Aspartate 1-decarboxylase alpha chain]
Cytoplasmic
A
Cytoplasm
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
AAT_ECOLI
P00509
aspC
b0928 JW0911
Aspartate aminotransferase (AspAT) (EC 2.6.1.1) (Transaminase A)
Peripheral inner membrane protein facing the cytoplasm
F1
Cytoplasm
Cytoplasmic (Experimental)
N/A
 
 
 
 
 
yes
yes
ASPA_ECOLI
P0AC38
aspA
b4139 JW4099
Aspartate ammonia-lyase (Aspartase) (EC 4.3.1.1)
Peripheral inner membrane protein facing the cytoplasm
F1
 
Cytoplasmic
N/A
 
TF
 
 
 
yes
yes
PYRB_ECOLI
P0A786
pyrB
b4245 JW4204
Aspartate carbamoyltransferase catalytic chain (EC 2.1.3.2) (Aspartate transcarbamylase) (ATCase)
Cytoplasmic
A
 
Cytoplasmic
N/A
 
TF
 
 
 
yes
yes
PYRI_ECOLI
P0A7F3
pyrI
b4244 JW4203
Aspartate carbamoyltransferase regulatory chain
Cytoplasmic
A
 
Cytoplasmic (Experimental)
N/A
 
 
 
 
 
yes
yes
ASNA_ECOLI
P00963
asnA
b3744 JW3722
Aspartate--ammonia ligase (EC 6.3.1.1) (Asparagine synthetase A)
Cytoplasmic
A
Cytoplasm
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
DHAS_ECOLI
P0A9Q9
asd

hom

b3433 JW3396
Aspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (ASADH) (EC 1.2.1.11)
Peripheral inner membrane protein facing the cytoplasm
F1
 
Cytoplasmic
IM (predicted-detected)
 
 
 
 
 
yes
yes
SYD_ECOLI
P21889
aspS

tls

b1866 JW1855
Aspartyl-tRNA synthetase (EC 6.1.1.12) (Aspartate--tRNA ligase) (AspRS)
Peripheral inner membrane protein facing the cytoplasm
F1
Cytoplasm
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
HIS1_ECOLI
P60757
hisG
b2019 JW2001
ATP phosphoribosyltransferase (ATP-PRT) (ATP-PRTase) (EC 2.4.2.17)
Peripheral inner membrane protein facing the cytoplasm
F1
Cytoplasm
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
ATPE_ECOLI
P0A6E6
atpC

papG uncC

b3731 JW3709
ATP synthase epsilon chain (ATP synthase F1 sector epsilon subunit) (F-ATPase epsilon subunit)
Peripheral inner membrane protein facing the cytoplasm
F1
Cell inner membrane | Peripheral membrane protein
Cytoplasmic (Experimental)
Soluble protein detected in Inner Membrane Fraction
 
 
 
 
 
no
yes
ATPG_ECOLI
P0ABA6
atpG

papC uncG

b3733 JW3711
ATP synthase gamma chain (ATP synthase F1 sector gamma subunit) (F-ATPase gamma subunit)
Peripheral inner membrane protein facing the cytoplasm
F1
Cell inner membrane | Peripheral membrane protein
Cytoplasmic (Experimental)
Soluble protein detected in Inner Membrane Fraction
 
 
 
 
 
yes
yes
ATPZ_ECOLI
P0ABC0
atpI

uncI

b3739 JW5611
ATP synthase protein I
Integral Inner Membrane
B
Cell inner membrane | Multi-pass membrane protein
Integral Membrane Protein
IM (predicted)
 
SRP
YidC
 
 
yes
yes
ATP6_ECOLI
P0AB98
atpB

papD uncB

b3738 JW3716
ATP synthase subunit a (ATP synthase F0 sector subunit a) (F-ATPase subunit 6)
Integral Inner Membrane
B
Cell inner membrane | Multi-pass membrane protein
Integral Membrane Protein (Experimental)
IM (predicted), Detected in IM Fraction
 
SRP
YidC
 
 
yes
yes
ATPA_ECOLI
P0ABB0
atpA

papA uncA

b3734 JW3712
ATP synthase subunit alpha (EC 3.6.3.14) (ATP synthase F1 sector subunit alpha) (F-ATPase subunit alpha)
Peripheral inner membrane protein facing the cytoplasm
F1
Cell inner membrane | Peripheral membrane protein
Cytoplasmic
IM (predicted)
 
TF
YidC
 
 
no
yes
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