STEPdb: Sub-cellular Topologies of E.coli Polypeptides.

View: E. coli K-12 / MG1655/ ATCC 47076 proteome  Export to Excel  Export to HTML  Export to XML  Export to CSV  

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E. coli K-12 / MG1655/ ATCC 47076 proteome

(mouse over and click on the one letter topology symbols to see which proteins of this specific subproteome are localized in each location)

Bacterial cell cartoon of sub-cellular locations


Protein ID
(Uniprot)
Accession
(Uniprot)
Gene Name
(Uniprot)
Order
Locus Name
Protein Name
(Uniprot)
Full Name
Symbol
Uniprot
EchoLOCATION
Extracellular Appendage
First Level
Targeting
Chaperoning
First Level
Secretion
System
Second Level
Targeting
Chaperoning
Second Level
Secretion
System
K-12 Core
Proteome
(yes/no)
K-12 Basic
Proteome
(yes/no)
RHMA_ECOLI
P76469
rhmA

yfaU

b2245 JW2239
2-keto-3-deoxy-L-rhamnonate aldolase (KDR aldolase) (EC 4.1.2.n3) (2-dehydro-3-deoxyrhamnonate aldolase) (2-keto-3-deoxy acid sugar aldolase)
Cytoplasmic
A
 
Cytoplasmic
IM (predicted)
 
 
 
 
 
yes
yes
KDGT_ECOLI
P0A712
kdgT
b3909 JW5560
2-keto-3-deoxygluconate permease (KDG permease)
Integral Inner Membrane
B
Cell inner membrane | Multi-pass membrane protein
Integral Membrane Protein
IM (predicted)
 
SRP
SEC
 
 
yes
yes
MHPD_ECOLI
P77608
mhpD
b0350 JW0341
2-keto-4-pentenoate hydratase (EC 4.2.1.80) (2-hydroxypentadienoic acid hydratase)
Cytoplasmic
A
 
Cytoplasmic
N/A
 
 
 
 
 
no
yes
PRPD_ECOLI
P77243
prpD

yahT

b0334 JW0325
2-methylcitrate dehydratase (EC 4.2.1.79)
Cytoplasmic
A
 
Cytoplasmic
N/A
 
 
 
 
 
no
yes
PRPC_ECOLI
P31660
prpC

yahS yzzD

b0333 JW0324
2-methylcitrate synthase (EC 2.3.3.5) (Citrate synthase 2) (Methylcitrate synthase)
Cytoplasmic
A
 
Cytoplasmic
N/A
 
 
 
 
 
no
yes
UBIF_ECOLI
P75728
ubiF

yleB

b0662 JW0659
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase (EC 1.14.13.-)
Cytoplasmic
A
 
Cytoplasmic
IM (predicted-detected)
 
 
 
 
 
yes
yes
UBIH_ECOLI
P25534
ubiH

visB

b2907 JW2875
2-octaprenyl-6-methoxyphenol hydroxylase (EC 1.14.13.-)
Peripheral inner membrane protein facing the cytoplasm
F1
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
ODO1_ECOLI
P0AFG3
sucA
b0726 JW0715
2-oxoglutarate dehydrogenase E1 component (EC 1.2.4.2) (Alpha-ketoglutarate dehydrogenase)
Peripheral inner membrane protein facing the cytoplasm
F1
 
Cytoplasmic
Soluble protein detected in Inner Membrane Fraction
 
TF
 
 
 
yes
yes
MEND_ECOLI
P17109
menD
b2264 JW5374
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase (SEPHCHC synthase) (EC 2.2.1.9) (Menaquinone biosynthesis protein menD)
Cytoplasmic
A
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
MENH_ECOLI
P37355
menH

yfbB

b2263 JW2258
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (SHCHC synthase) (EC 4.2.99.20)
Cytoplasmic
A
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
MENE_ECOLI
P37353
menE
b2260 JW2255
2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (o-succinylbenzoyl-CoA synthetase) (OSB-CoA synthetase)
Peripheral inner membrane protein facing the cytoplasm
F1
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
RLMB_ECOLI
P63177
rlmB

yjfH

b4180 JW4138
23S rRNA (guanosine-2'-O-)-methyltransferase rlmB (EC 2.1.1.-) (23S rRNA Gm2251 2'-O-methyltransferase)
Cytoplasmic
A
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
RLMD_ECOLI
P55135
rlmD

rumA ygcA

b2785 JW2756
23S rRNA (uracil-5-)-methyltransferase rumA (EC 2.1.1.-) (23S rRNA(M-5-U1939)-methyltransferase)
Cytoplasmic
A
 
Cytoplasmic
N/A
 
 
 
 
 
no
yes
RLMC_ECOLI
P75817
rlmC

rumB ybjF

b0859 JW0843
23S rRNA (uracil-5-)-methyltransferase rumB (EC 2.1.1.-) (23S rRNA(M-5-U747)-methyltransferase)
Cytoplasmic
A
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
FER_ECOLI
P0A9R4
fdx
b2525 JW2509
2Fe-2S ferredoxin
Cytoplasmic
A
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
CYSQ_ECOLI
P22255
cysQ

amtA

b4214 JW4172
3'(2'),5'-bisphosphate nucleotidase cysQ (EC 3.1.3.7) (3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase) (3'-phosphoadenosine 5'-phosphate phosphatase) (PAP phosphatase) (DPNPase)
Peripheral inner membrane protein facing the cytoplasm
F1
CytoplasmCell inner membrane | Peripheral membrane protein | Cytoplasmic side
Membrane associated (Experimental)
N/A
 
 
 
 
 
no
yes
RIBB_ECOLI
P0A7J0
ribB

htrP

b3041 JW3009
3,4-dihydroxy-2-butanone 4-phosphate synthase (DHBP synthase) (EC 4.1.99.12)
Peripheral inner membrane protein facing the cytoplasm
F1
Cell membrane | Peripheral membrane protein
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
MHPA_ECOLI
P77397
mhpA
b0347 JW0338
3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase (3-HCI hydroxylase) (3-HPP hydroxylase) (EC 1.14.13.n3)
Cytoplasmic
A
 
Cytoplasmic
IM (predicted)
 
 
 
 
 
no
yes
AROD_ECOLI
P05194
aroD
b1693 JW1683
3-dehydroquinate dehydratase (3-dehydroquinase) (EC 4.2.1.10) (Type I DHQase)
Cytoplasmic
A
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
AROB_ECOLI
P07639
aroB
b3389 JW3352
3-dehydroquinate synthase (EC 4.2.3.4)
Cytoplasmic
A
Cytoplasm
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
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