STEPdb: Sub-cellular Topologies of E.coli Polypeptides.

View: E. coli K-12 / MG1655/ ATCC 47076 proteome  Export to Excel  Export to HTML  Export to XML  Export to CSV  

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E. coli K-12 / MG1655/ ATCC 47076 proteome

(mouse over and click on the one letter topology symbols to see which proteins of this specific subproteome are localized in each location)

Bacterial cell cartoon of sub-cellular locations


Protein ID
(Uniprot)
Accession
(Uniprot)
Gene Name
(Uniprot)
Order
Locus Name
Protein Name
(Uniprot)
Full Name
Symbol
Uniprot
EchoLOCATION
Extracellular Appendage
First Level
Targeting
Chaperoning
First Level
Secretion
System
Second Level
Targeting
Chaperoning
Second Level
Secretion
System
K-12 Core
Proteome
(yes/no)
K-12 Basic
Proteome
(yes/no)
UBIG_ECOLI
P17993
ubiG

pufX yfaB

b2232 JW2226
3-demethylubiquinone-9 3-methyltransferase (EC 2.1.1.64) (3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase) (DHHB methyltransferase)
Cytoplasmic
A
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
KDSC_ECOLI
P0ABZ4
kdsC

yrbI yrbJ

b3198 JW3165
3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (EC 3.1.3.45) (KDO 8-P phosphatase)
Peripheral inner membrane protein facing the cytoplasm
F1
 
Cytoplasmic (Experimental)
N/A
 
 
 
 
 
yes
yes
KDTA_ECOLI
P0AC75
waaA

kdtA

b3633 JW3608
3-deoxy-D-manno-octulosonic-acid transferase (EC 2.4.-.-) (KDO transferase)
Integral Inner Membrane
B
Cell inner membrane | Single-pass membrane protein
Cytoplasmic
IM (predicted)
 
SRP
SEC
 
 
yes
yes
KDSB_ECOLI
P04951
kdsB
b0918 JW0901
3-deoxy-manno-octulosonate cytidylyltransferase (EC 2.7.7.38) (CMP-2-keto-3-deoxyoctulosonic acid synthase) (CKS) (CMP-KDO synthase)
Cytoplasmic
A
Cytoplasm
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
FABA_ECOLI
P0A6Q3
fabA
b0954 JW0937
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.60) (Beta-hydroxydecanoyl thioester dehydrase)
Cytoplasmic
A
Cytoplasm
Cytoplasmic
N/A
 
TF
 
 
 
yes
yes
LEUC_ECOLI
P0A6A6
leuC
b0072 JW0071
3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) (Alpha-IPM isomerase) (IPMI) (Isopropylmalate isomerase)
Cytoplasmic
A
 
Cytoplasmic
N/A
 
 
 
 
 
no
yes
LEUD_ECOLI
P30126
leuD
b0071 JW0070
3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) (Alpha-IPM isomerase) (IPMI) (Isopropylmalate isomerase)
Cytoplasmic
A
 
Cytoplasmic
IM (predicted)
 
 
 
 
 
no
yes
LEU3_ECOLI
P30125
leuB
b0073 JW5807
3-isopropylmalate dehydrogenase (EC 1.1.1.85) (3-IPM-DH) (Beta-IPM dehydrogenase) (IMDH)
Cytoplasmic
A
Cytoplasm
Cytoplasmic
N/A
 
 
 
 
 
no
yes
SGBH_ECOLI
P37678
sgbH

yiaQ

b3581 JW3553
3-keto-L-gulonate-6-phosphate decarboxylase sgbH (KGPDC) (EC 4.1.1.85) (3-dehydro-L-gulonate-6-phosphate decarboxylase)
Cytoplasmic
A
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
ULAD_ECOLI
P39304
ulaD

sgaH yjfV

b4196 JW4154
3-keto-L-gulonate-6-phosphate decarboxylase ulaD (EC 4.1.1.85) (3-dehydro-L-gulonate-6-phosphate decarboxylase) (KGPDC) (L-ascorbate utilization protein D)
Cytoplasmic
A
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
FADA_ECOLI
P21151
fadA

oldA

b3845 JW5578
3-ketoacyl-CoA thiolase (EC 2.3.1.16) (Acetyl-CoA acyltransferase) (Beta-ketothiolase) (Fatty acid oxidation complex subunit beta)
Cytoplasmic
A
Cytoplasm
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
FADI_ECOLI
P76503
fadI

yfcY

b2342 JW2339
3-ketoacyl-CoA thiolase (EC 2.3.1.16) (ACSs) (Acetyl-CoA acyltransferase) (Acyl-CoA ligase) (Beta-ketothiolase) (Fatty acid oxidation complex subunit beta)
Peripheral inner membrane protein facing the cytoplasm
F1
Cytoplasm
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
THTM_ECOLI
P31142
sseA
b2521 JW2505
3-mercaptopyruvate sulfurtransferase (MST) (EC 2.8.1.2) (Rhodanese-like protein)
Cytoplasmic
A
Cytoplasm
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
PANB_ECOLI
P31057
panB
b0134 JW0130
3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) (Ketopantoate hydroxymethyltransferase) (KPHMT)
Cytoplasmic
A
Cytoplasm
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
UBID_ECOLI
P0AAB4
ubiD

yigC yigY

b3843 JW3819
3-octaprenyl-4-hydroxybenzoate carboxy-lyase (EC 4.1.1.-) (Polyprenyl p-hydroxybenzoate decarboxylase)
Peripheral inner membrane protein facing the cytoplasm
F1
Cell membrane | Peripheral membrane protein
Cytoplasmic
IM (predicted)
 
 
 
 
 
yes
yes
UBIX_ECOLI
P0AG03
ubiX

dedF

b2311 JW2308
3-octaprenyl-4-hydroxybenzoate carboxy-lyase (EC 4.1.1.-) (Polyprenyl p-hydroxybenzoate decarboxylase)
Cytoplasmic
A
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
FABG_ECOLI
P0AEK2
fabG
b1093 JW1079
3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) (3-ketoacyl-acyl carrier protein reductase)
Peripheral inner membrane protein facing the cytoplasm
F1
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
FABB_ECOLI
P0A953
fabB

fabC

b2323 JW2320
3-oxoacyl-[acyl-carrier-protein] synthase 1 (EC 2.3.1.41) (3-oxoacyl-[acyl-carrier-protein] synthase I) (Beta-ketoacyl-ACP synthase I) (KAS I)
Peripheral inner membrane protein facing the cytoplasm
F1
Cytoplasm
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
FABF_ECOLI
P0AAI5
fabF

fabJ

b1095 JW1081
3-oxoacyl-[acyl-carrier-protein] synthase 2 (EC 2.3.1.179) (3-oxoacyl-[acyl-carrier-protein] synthase II) (Beta-ketoacyl-ACP synthase II) (KAS II)
Peripheral inner membrane protein facing the cytoplasm
F1
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
FABH_ECOLI
P0A6R0
fabH
b1091 JW1077
3-oxoacyl-[acyl-carrier-protein] synthase 3 (EC 2.3.1.180) (3-oxoacyl-[acyl-carrier-protein] synthase III) (Beta-ketoacyl-ACP synthase III) (KAS III) (EcFabH)
Cytoplasmic
A
Cytoplasm
Cytoplasmic
IM (predicted)
 
 
 
 
 
yes
yes
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