STEPdb: Sub-cellular Topologies of E.coli Polypeptides.

View: E. coli K-12 / MG1655/ ATCC 47076 proteome  Export to Excel  Export to HTML  Export to XML  Export to CSV  

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E. coli K-12 / MG1655/ ATCC 47076 proteome

(mouse over and click on the one letter topology symbols to see which proteins of this specific subproteome are localized in each location)

Bacterial cell cartoon of sub-cellular locations


Protein ID
(Uniprot)
Accession
(Uniprot)
Gene Name
(Uniprot)
Order
Locus Name
Protein Name
(STEPdb)
Full Name
Symbol
Uniprot
EchoLOCATION
Extracellular Appendage
First Level
Targeting
Chaperoning
First Level
Secretion
System
Second Level
Targeting
Chaperoning
Second Level
Secretion
System
K-12 Core
Proteome
(yes/no)
K-12 Basic
Proteome
(yes/no)
SYD_ECOLI
P21889
aspS

tls

b1866 JW1855
cytoplasmic peripheral IM protein, Aspartate--tRNA ligase AspS
Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm
A, F1
Cytoplasm
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
FTSQ_ECOLI
P06136
ftsQ
b0093 JW0091
integral IM protein (SEC in IM), Cell division FtsQ
Integral Inner Membrane
B
Cell inner membrane
Membrane anchored
IM (predicted)
 
SRP
SEC
 
 
yes
yes
CYOA_ECOLI
P0ABJ1
cyoA
b0432 JW0422
integral IM protein (SEC in IM), Cytochrome bo(3) ubiquinol oxidase subunit 2 CyoA
Integral Inner Membrane
B
Cell inner membrane
Integral Membrane Protein
IM (predicted), Detected in IM Fraction
 
SRP
SEC
 
 
yes
yes
YIDC_ECOLI
P25714
yidC
b3705 JW3683
integral IM protein (SEC in IM), insertase YidC
Integral Inner Membrane
B
Cell inner membrane
Integral Membrane Protein
IM (predicted), Detected in IM Fraction
 
SRP (exp)
SEC
 
 
yes
yes
HFLC_ECOLI
P0ABC3
hflC

hflA

b4175 JW4133
integral IM protein (SEC in IM), Modulator of FtsH protease HflC
Integral Inner Membrane
B
Cell inner membrane
Membrane anchored (Experimental)
Soluble protein detected in Inner Membrane Fraction
 
SRP
SEC
 
 
yes
yes
HFLK_ECOLI
P0ABC7
hflK

hflA

b4174 JW4132
integral IM protein (SEC in IM), Modulator of FtsH protease HflK
Integral Inner Membrane
B
Cell inner membrane
Membrane anchored
IM (predicted)
 
SRP
SEC
 
 
yes
no
PPID_ECOLI
P0ADY1
ppiD

ybaU

b0441 JW0431
integral IM protein (SEC in IM), Peptidyl-prolyl cis-trans isomerase D PpiD
Integral Inner Membrane
B
Cell inner membrane
Membrane anchored (Experimental)
IM (predicted), Detected in IM Fraction
 
SRP
SEC
 
 
yes
yes
SECG_ECOLI
P0AG99
secG
b3175 JW3142
integral IM protein (SEC in IM), Protein-export SecG
Integral Inner Membrane
B
Cell inner membrane; Multi-pass membrane protein
Integral Membrane Protein
IM (predicted), Detected in IM Fraction
 
SRP
SEC
 
 
yes
yes
PTM3C_ECOLI
P00550
mtlA
b3599 JW3573
integral IM protein (SEC in IM), PTS system mannitol-specific EIICBA component MtlA
Integral Inner Membrane
B
Cell inner membrane
Integral Membrane Protein
IM (predicted), Detected in IM Fraction
 
SRP (exp)
SEC
 
 
yes
yes
SECE_ECOLI
P0AG96
secE

prlG

b3981 JW3944
integral IM protein (SEC in IM), translocase subunit SecE
Integral Inner Membrane
B
Cell inner membrane
Integral Membrane Protein
IM (predicted), Detected in IM Fraction
 
SRP (exp)
SEC
 
 
yes
yes
SECY_ECOLI
P0AGA2
secY

prlA

b3300 JW3262
integral IM protein (SEC in IM), translocase subunit SecY
Integral Inner Membrane
B
Cell inner membrane; Multi-pass membrane protein
Integral Membrane Protein (Experimental)
IM (predicted), Detected in IM Fraction
 
SRP
SEC
 
 
yes
yes
YFGM_ECOLI
P76576
yfgM
b2513 JW2497
integral IM protein (SEC in IM), UPF0070 YfgM
Integral Inner Membrane
B
Membrane
Membrane anchored
IM (predicted), Detected in IM Fraction
 
SRP
SEC
 
 
yes
yes
OMPA_ECOLI
P0A910
ompA

con tolG tut

b0957 JW0940
OM b-barrel protein (SEC through IM, inserted in OM by BAM), OmpA
Outer Membrane b-barrel protein
H
Cell outer membrane
Outer Membrane ??-barrel protein (Experimental)
Soluble protein detected in Inner Membrane Fraction
 
TF
SEC
SKP,SURA,DEGP,DSBA
BAM: β-Barrel Assembly Machinery
yes
yes
MLTA_ECOLI
P0A935
mltA

mlt ygdM

b2813 JW2784
OM lipoprotein (SEC through IM), inserted in OM by LOL), Membrane-bound lytic murein transglycosylase A MltA
Outer Membrane Lipoprotein
I
Cell outer membrane; Lipid-anchor
Outer membrane Lipoprotein (Experimental)
N/A
 
 
SEC
 
LOL: Localization Of Lipoproteins
no
yes
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