STEPdb: Sub-cellular Topologies of E.coli Polypeptides.

View: E.coli K-12 (MG1655) proteome  Export to Excel  Export to HTML  Export to XML  Export to CSV  

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E.coli K-12 (MG1655) proteome

Bacterial cell cartoon of sub-cellular locations


Protein ID
(Uniprot)
Accession
(Uniprot)
Gene Name
(Uniprot)
Order
Locus Name
Protein Name
(Uniprot)
Full Name
Symbol
Uniprot
EchoLOCATION
Extracellular Appendage
First Level
Targeting
Chaperoning
First Level
Secretion
System
Second Level
Targeting
Chaperoning
Second Level
Secretion
System
K-12 Core
Proteome
(yes/no)
K-12 Basic
Proteome
(yes/no)
SKP_ECOLI
P0AEU7
skp

hlpA ompH

b0178 JW0173
Chaperone protein skp (DNA-binding 17 kDa protein) (Histone-like protein HLP-1) (Seventeen kilodalton protein)
Periplasmic
G
Secreted
Periplasmic(experimental)
N/A
 
 
SEC
 
 
yes
yes
SURA_ECOLI
P0ABZ6
surA
b0053 JW0052
Chaperone surA (Peptidyl-prolyl cis-trans isomerase surA) (PPIase surA) (EC 5.2.1.8) (Rotamase surA) (Survival protein A)
Periplasmic
G
Secreted
Periplasmic (Experimental)
N/A
 
 
SEC
 
 
yes
yes
DSBB_ECOLI
P0A6M2
dsbB

roxB ycgA

b1185 JW5182
Disulfide bond formation protein B (Disulfide oxidoreductase)
Integral Inner Membrane
B
Cell inner membrane | Multi-pass membrane protein
Integral Membrane Protein
IM (predicted), Detected in IM Fraction
 
SRP
YidC
 
 
yes
yes
FKBB_ECOLI
P0A9L3
fklB

ytfC

b4207 JW5746
FKBP-type 22 kDa peptidyl-prolyl cis-trans isomerase (FKBP22) (PPIase) (EC 5.2.1.8) (Rotamase)
Cytoplasmic
A
CytoplasmPeriplasm
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
FKBA_ECOLI
P45523
fkpA

yzzS

b3347 JW3309
FKBP-type peptidyl-prolyl cis-trans isomerase fkpA (PPIase) (EC 5.2.1.8) (Rotamase)
Periplasmic
G
Secreted
Periplasmic (Experimental)
N/A
 
SecB
SEC
 
 
yes
yes
BAMC_ECOLI
P0A903
nlpB

dapX nlpB

b2477 JW2462
Lipoprotein 34
Outer Membrane Lipoprotein
I
Cell outer membrane | Lipid-anchor
Outer membrane Lipoprotein (Experimental)
Soluble protein detected in Inner Membrane Fraction
 
 
SEC
 
LOL: Localization Of Lipoproteins
yes
yes
BAMB_ECOLI
P77774
yfgL

yfgL

b2512 JW2496
Lipoprotein yfgL
Outer Membrane Lipoprotein
I
Cell outer membrane | Lipid-anchor
Outer membrane Lipoprotein (Experimental)
Soluble protein detected in Inner Membrane Fraction
 
 
SEC
 
LOL: Localization Of Lipoproteins
yes
yes
BAMA_ECOLI
P0A940
bamA

yaeT yzzN yzzY

b0177 JW0172
Outer membrane protein assembly factor yaeT (Omp85)
Outer Membrane b-barrel protein
H
Single-pass type I membrane protein
Outer Membrane ss-barrel protein(experimental)
Soluble protein detected in Inner Membrane Fraction
 
 
SEC
 
BAM: β-Barrel Assembly Machinery
yes
yes
DEGP_ECOLI
P0C0V0
degP

htrA ptd

b0161 JW0157
Periplasmic serine endoprotease DegP
Periplasmic
G
Secreted
Periplasmic (Experimental)
N/A
 
SecB
SEC
DsbA
 
yes
yes
BAME_ECOLI
P0A937
smpA

smpA

b2617 JW2598
Small protein A
Outer Membrane Lipoprotein
I
Cell outer membrane | Lipid-anchor
Outer membrane Lipoprotein
Soluble protein detected in Inner Membrane Fraction
 
 
SEC
 
LOL: Localization Of Lipoproteins
yes
yes
DSBA_ECOLI
P0AEG4
dsbA

dsf ppfA

b3860 JW3832
Thiol:disulfide interchange protein DsbA
Periplasmic
G
Secreted
Periplasmic (Experimental)
N/A
 
SRP (exp)
SEC
 
 
yes
yes
DSBC_ECOLI
P0AEG6
dsbC

xprA

b2893 JW2861
Thiol:disulfide interchange protein DsbC
Periplasmic
G
Secreted
Periplasmic (Experimental)
N/A
 
 
SEC
 
 
yes
yes
DSBD_ECOLI
P36655
dsbD

cutA2 cycZ dipZ

b4136 JW5734
Thiol:disulfide interchange protein dsbD (EC 1.8.1.8) (C-type cytochrome biogenesis protein cycZ) (Inner membrane copper tolerance protein) (Protein-disulfide reductase) (Disulfide reductase)
Integral Inner Membrane
B
Cell inner membrane | Multi-pass membrane protein
Integral Membrane Protein (Experimental)
IM (predicted), Detected in IM Fraction
 
SRP
SEC
 
 
yes
yes
DSBE_ECOLI
P0AA86
dsbE

ccmG yejQ

b2195 JW2183
Thiol:disulfide interchange protein dsbE (Cytochrome c biogenesis protein CcmG)
Integral Inner Membrane
B
Cell inner membrane | Single-pass membrane protein | Periplasmic side
Periplasmic with N-terminal membrane anchor (Experimental)
N/A
 
SRP
SEC
 
 
yes
yes
DSBG_ECOLI
P77202
dsbG

ybdP

b0604 JW0597
Thiol:disulfide interchange protein DsbG
Periplasmic
G
Secreted
Periplasmic (Experimental)
N/A
 
 
SEC
 
 
yes
yes
BAMD_ECOLI
P0AC02
bamD

yfiO

b2595 JW2577
UPF0169 lipoprotein yfiO
Outer Membrane Lipoprotein
I
Cell outer membrane | Lipid-anchor
Outer membrane Lipoprotein(experimental)
Soluble protein detected in Inner Membrane Fraction
 
 
SEC
 
LOL: Localization Of Lipoproteins
yes
yes
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