STEPdb: Sub-cellular Topologies of E.coli Polypeptides.

View: E. coli K-12 / MG1655/ ATCC 47076 proteome  Export to Excel  Export to HTML  Export to XML  Export to CSV  

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E. coli K-12 / MG1655/ ATCC 47076 proteome

(mouse over and click on the one letter topology symbols to see which proteins of this specific subproteome are localized in each location)

Bacterial cell cartoon of sub-cellular locations


Protein ID
(Uniprot)
Accession
(Uniprot)
Gene Name
(Uniprot)
Order
Locus Name
Protein Name
(STEPdb)
Full Name
Symbol
Uniprot
EchoLOCATION
Extracellular Appendage
First Level
Targeting
Chaperoning
First Level
Secretion
System
Second Level
Targeting
Chaperoning
Second Level
Secretion
System
K-12 Core
Proteome
(yes/no)
K-12 Basic
Proteome
(yes/no)
DNAK_ECOLI
P0A6Y8
dnaK

groP grpF seg

b0014 JW0013
cytoplasmic peripheral IM protein of Hsp70 family, Chaperone DnaK
Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm
A, F1
Cytoplasm
Cytoplasmic (Experimental)
Soluble protein detected in Inner Membrane Fraction
 
 
 
 
 
yes
yes
SYD_ECOLI
P21889
aspS

tls

b1866 JW1855
cytoplasmic peripheral IM protein, Aspartate--tRNA ligase AspS
Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm
A, F1
Cytoplasm
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
ATPA_ECOLI
P0ABB0
atpA

papA uncA

b3734 JW3712
cytoplasmic peripheral IM protein, ATP synthase subunit alpha AtpA
Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm
A, F1
Cell inner membrane
Cytoplasmic
IM (predicted)
 
TF
 
 
 
no
yes
ATPB_ECOLI
P0ABB4
atpD

papB uncD

b3732 JW3710
cytoplasmic peripheral IM protein, ATP synthase subunit beta AtpD
Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm
A, F1
Cell inner membrane; Peripheral membrane protein
Cytoplasmic
Soluble protein detected in Inner Membrane Fraction
 
 
 
 
 
yes
yes
CFA_ECOLI
P0A9H7
cfa

cdfA

b1661 JW1653
cytoplasmic peripheral IM protein, Cyclopropane-fatty-acyl-phospholipid synthase Cfa
Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm
A, F1
Cytoplasm
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
DADA_ECOLI
P0A6J5
dadA

dadR

b1189 JW1178
cytoplasmic peripheral IM protein, D-amino acid dehydrogenase DadA
Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm
A, F1
Cell inner membrane
Cytoplasmic
Soluble protein detected in Inner Membrane Fraction
 
TF
 
 
 
yes
yes
BETA_ECOLI
P17444
betA
b0311 JW0303
cytoplasmic peripheral IM protein, Oxygen-dependent choline dehydrogenase BetA
Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm
A, F1
Cell membrane
Cytoplasmic
N/A
 
 
 
 
 
no
yes
DLD_ECOLI
P06149
dld
b2133 JW2121
cytoplasmic peripheral IM protein, Quinone-dependent D-lactate dehydrogenase Dld
Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm
A, F1
Cell inner membrane
Cytoplasmic
Soluble protein detected in Inner Membrane Fraction
 
 
 
 
 
yes
yes
SRP54_ECOLI
P0AGD7
ffh
b2610 JW5414
cytoplasmic peripheral IM protein, Signal recognition particle Ffh
Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm
A, F1
Cytoplasm
Cytoplasmic
N/A
 
TF
 
 
 
yes
yes
FTSY_ECOLI
P10121
ftsY
b3464 JW3429
cytoplasmic peripheral IM protein, Signal recognition particle receptor FtsY
Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm
A, F1
Cell inner membrane
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
SFMC_ECOLI
P77249
sfmC
b0531 JW0520
Fimbrial periplasmic protein (SEC through IM), Probable chaperone SfmC
Periplasmic
G
Periplasm
Periplasmic
N/A
fimbriae
SRP (exp)
SEC
SurA
 
yes
yes
FTSQ_ECOLI
P06136
ftsQ
b0093 JW0091
integral IM protein (SEC in IM), Cell division FtsQ
Integral Inner Membrane
B
Cell inner membrane
Membrane anchored
IM (predicted)
 
SRP
SEC
 
 
yes
yes
CYOA_ECOLI
P0ABJ1
cyoA
b0432 JW0422
integral IM protein (SEC in IM), Cytochrome bo(3) ubiquinol oxidase subunit 2 CyoA
Integral Inner Membrane
B
Cell inner membrane
Integral Membrane Protein
IM (predicted), Detected in IM Fraction
 
SRP
SEC
 
 
yes
yes
YIDC_ECOLI
P25714
yidC
b3705 JW3683
integral IM protein (SEC in IM), insertase YidC
Integral Inner Membrane
B
Cell inner membrane
Integral Membrane Protein
IM (predicted), Detected in IM Fraction
 
SRP (exp)
SEC
 
 
yes
yes
HFLC_ECOLI
P0ABC3
hflC

hflA

b4175 JW4133
integral IM protein (SEC in IM), Modulator of FtsH protease HflC
Integral Inner Membrane
B
Cell inner membrane
Membrane anchored (Experimental)
Soluble protein detected in Inner Membrane Fraction
 
SRP
SEC
 
 
yes
yes
HFLK_ECOLI
P0ABC7
hflK

hflA

b4174 JW4132
integral IM protein (SEC in IM), Modulator of FtsH protease HflK
Integral Inner Membrane
B
Cell inner membrane
Membrane anchored
IM (predicted)
 
SRP
SEC
 
 
yes
no
NUOK_ECOLI
P0AFE4
nuoK
b2279 JW2274
integral IM protein (SEC in IM), NADH-quinone oxidoreductase subunit K NuoK
Integral Inner Membrane
B
Cell inner membrane; Multi-pass membrane protein
Integral Membrane Protein
IM (predicted), Detected in IM Fraction
 
SRP
SEC
 
 
yes
yes
PPID_ECOLI
P0ADY1
ppiD

ybaU

b0441 JW0431
integral IM protein (SEC in IM), Peptidyl-prolyl cis-trans isomerase D PpiD
Integral Inner Membrane
B
Cell inner membrane
Membrane anchored (Experimental)
IM (predicted), Detected in IM Fraction
 
SRP
SEC
 
 
yes
yes
PSPB_ECOLI
P0AFM9
pspB
b1305 JW1298
integral IM protein (SEC in IM), Phage shock B PspB
Integral Inner Membrane
B
Cell inner membrane; Single-pass membrane protein
Membrane anchored
IM (predicted), Detected in IM Fraction
 
SRP
SEC
 
 
no
yes
PSPC_ECOLI
P0AFN2
pspC
b1306 JW1299
integral IM protein (SEC in IM), Phage shock C PspC
Integral Inner Membrane
B
Cell inner membrane
Membrane anchored
IM (predicted)
 
SRP
SEC
 
 
yes
no
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