STEPdb: Sub-cellular Topologies of E.coli Polypeptides.

View: E. coli K-12 / MG1655/ ATCC 47076 proteome  Export to Excel  Export to HTML  Export to XML  Export to CSV  

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E. coli K-12 / MG1655/ ATCC 47076 proteome

(mouse over and click on the one letter topology symbols to see which proteins of this specific subproteome are localized in each location)

Bacterial cell cartoon of sub-cellular locations


Protein ID
(Uniprot)
Accession
(Uniprot)
Gene Name
(Uniprot)
Order
Locus Name
Protein Name
(STEPdb)
Full Name
Symbol
Uniprot
EchoLOCATION
Extracellular Appendage
First Level
Targeting
Chaperoning
First Level
Secretion
System
Second Level
Targeting
Chaperoning
Second Level
Secretion
System
K-12 Core
Proteome
(yes/no)
K-12 Basic
Proteome
(yes/no)
FLIE_ECOLI
P0A8T5
fliE

fla AI flaN

b1937 JW1921
Flagellar periplasmic peripheral IM protein (Flagellum secreted through IM), hook-basal body complex FliE
Peripheral inner membrane protein facing the periplasm
F2
Bacterial flagellum basal body
Cytoplasmic
N/A
flagellum
 
Flagellum
 
 
no
yes
FECB_ECOLI
P15028
fecB
b4290 JW4250
periplasmic & peripheral IM protein (SEC through IM), Fe(3+) dicitrate-binding periplasmic FecB
Peripheral inner membrane protein facing the periplasm, periplasmic
F2, G
Secreted
Periplasmic (Experimental)
N/A
 
 
SEC
 
 
no
yes
MALE_ECOLI
P0AEX9
malE
b4034 JW3994
periplasmic & peripheral IM protein (SEC through IM), Maltose/maltodextrin-binding periplasmic MalE
Peripheral inner membrane protein facing the periplasm, periplasmic
F2, G
Periplasm
Periplasmic (Experimental)
N/A
 
SecB
SEC
SURA,SKP,YfgM
 
yes
yes
IAP_ECOLI
P10423
iap
b2753 JW2723
periplasmic peripheral IM protein (SEC through IM), Alkaline phosphatase isozyme conversion Iap
Peripheral inner membrane protein facing the periplasm
F2
 
Membrane associated (Experimental)
N/A
 
 
SEC
 
 
yes
yes
CUSB_ECOLI
P77239
cusB

ylcD

b0574 JW0563
periplasmic peripheral IM protein (SEC through IM), Cation efflux system CusB
Peripheral inner membrane protein facing the periplasm
F2
 
Membrane anchored
N/A
 
 
SEC
 
 
yes
yes
CPXP_ECOLI
P0AE85
cpxP

yiiO

b4484 JW5558
periplasmic peripheral IM protein (SEC through IM), CpxP
Peripheral inner membrane protein facing the periplasm
F2
Periplasm
Membrane associated (Experimental)
N/A
 
 
SEC
 
 
yes
yes
DACA_ECOLI
P0AEB2
dacA

pfv

b0632 JW0627
periplasmic peripheral IM protein (SEC through IM), D-alanyl-D-alanine carboxypeptidase DacA
Peripheral inner membrane protein facing the periplasm
F2
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side
Membrane anchored (Experimental)
Soluble protein detected in Inner Membrane Fraction
 
 
SEC
 
 
yes
yes
DACB_ECOLI
P24228
dacB
b3182 JW3149
periplasmic peripheral IM protein (SEC through IM), D-alanyl-D-alanine carboxypeptidase DacB
Peripheral inner membrane protein facing the periplasm
F2
Periplasm
Membrane anchored (Experimental)
N/A
 
 
SEC
 
 
yes
yes
DACC_ECOLI
P08506
dacC
b0839 JW0823
periplasmic peripheral IM protein (SEC through IM), D-alanyl-D-alanine carboxypeptidase DacC
Peripheral inner membrane protein facing the periplasm
F2
Cell inner membrane
Membrane anchored (Experimental)
Soluble protein detected in Inner Membrane Fraction
 
 
SEC
 
 
yes
yes
DACD_ECOLI
P33013
dacD

phsE yeeC

b2010 JW5329
periplasmic peripheral IM protein (SEC through IM), D-alanyl-D-alanine carboxypeptidase DacD
Peripheral inner membrane protein facing the periplasm
F2
Cell inner membrane
Membrane anchored (Experimental)
N/A
 
 
SEC
 
 
yes
yes
MDTA_ECOLI
P76397
mdtA

yegM

b2074 JW5338
periplasmic peripheral IM protein (SEC through IM), Multidrug resistance MdtA
Peripheral inner membrane protein facing the periplasm
F2
Cell inner membrane
Membrane anchored
N/A
 
 
SEC
 
 
yes
yes
PRC_ECOLI
P23865
prc

tsp

b1830 JW1819
periplasmic peripheral IM protein (SEC through IM), Tail-specific protease Prc
Peripheral inner membrane protein facing the periplasm
F2
Cell inner membrane; Peripheral membrane protein; Periplasmic side
Periplasmic (Experimental)
N/A
 
 
SEC
 
 
yes
yes
YADE_ECOLI
P31666
yadE
b0130 JW0126
periplasmic peripheral IM protein (SEC through IM), YadE
Peripheral inner membrane protein facing the periplasm
F2
 
Periplasmic
N/A
 
 
SEC
 
 
yes
yes
YDGA_ECOLI
P77804
ydgA
b1614 JW1606
periplasmic peripheral IM protein (SEC through IM), YdgA
Peripheral inner membrane protein facing the periplasm
F2
Cell inner membrane
Cytoplasmic
Soluble protein detected in Inner Membrane Fraction
 
 
SEC
 
 
yes
yes
FDNG_ECOLI
P24183
fdnG
b1474 JW1470
periplasmic peripheral IM protein (TAT through IM), Formate dehydrogenase, nitrate-inducible, major subunit FdnG
Peripheral inner membrane protein facing the periplasm
F2
Periplasm
Membrane associated (Experimental)
N/A
 
 
TAT
 
 
no
yes
YNFE_ECOLI
P77374
ynfE
b1587 JW1579
periplasmic peripheral IM protein (TAT through IM), Putative dimethyl sulfoxide reductase chain YnfE
Peripheral inner membrane protein facing the periplasm
F2
Cell membrane
Periplasmic
N/A
 
 
TAT
 
 
yes
yes
DMSB_ECOLI
P18776
dmsB
b0895 JW0878
periplasmic peripheral IM protein (TAT via piggyback through IM), Anaerobic dimethyl sulfoxide reductase chain B DmsB
Peripheral inner membrane protein facing the periplasm
F2
 
Cytoplasmic
N/A
 
 
TAT (piggyback)
 
 
yes
yes
MBHM_ECOLI
P0ACE0
hybC
b2994 JW2962
periplasmic peripheral IM protein (TAT via piggyback through IM), Hydrogenase-2 large chain HybC
Peripheral inner membrane protein facing the periplasm
F2
Cell membrane; Peripheral membrane protein
Periplasmic (Experimental)
Soluble protein detected in Inner Membrane Fraction
 
 
TAT (piggyback)
 
 
yes
yes
YNFG_ECOLI
P0AAJ1
ynfG
b1589 JW1581
periplasmic peripheral IM protein (TAT via piggyback through IM), Probable anaerobic dimethyl sulfoxide reductase chain YnfG
Peripheral inner membrane protein facing the periplasm
F2
 
Periplasmic
N/A
 
 
TAT (piggyback)
 
 
yes
yes
DMSA_ECOLI
P18775
dmsA
b0894 JW5118
periplasmic peripheral IM protein (TAT-SEC through IM), Dimethyl sulfoxide reductase DmsA
Peripheral inner membrane protein facing the periplasm
F2
Cell membrane
Periplasmic (Experimental)
Soluble protein detected in Inner Membrane Fraction
 
DmsD
TAT,SEC
 
 
yes
yes
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