STEPdb: Sub-cellular Topologies of E.coli Polypeptides.

View: E.coli K-12 (MG1655) Sec membranome  Export to Excel  Export to HTML  Export to XML  Export to CSV  

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E.coli K-12 (MG1655) Sec membranome

(mouse over and click on the one letter topology symbols to see which proteins of this specific subproteome are localized in each location)

Bacterial cell cartoon of sub-cellular locations


Protein ID
(Uniprot)
Accession
(Uniprot)
Gene Name
(Uniprot)
Order
Locus Name
Protein Name
(Uniprot)
Full Name
Symbol
Uniprot
EchoLOCATION
Extracellular Appendage
First Level
Targeting
Chaperoning
First Level
Secretion
System
Second Level
Targeting
Chaperoning
Second Level
Secretion
System
K-12 Core
Proteome
(yes/no)
K-12 Basic
Proteome
(yes/no)
ATKC_ECOLI
P03961
kdpC
b0696 JW0684
Potassium-transporting ATPase C chain (EC 3.6.3.12) (ATP phosphohydrolase [potassium-transporting] C chain) (Potassium-binding and translocating subunit C) (Potassium-translocating ATPase C chain)
Integral Inner Membrane
B
N/A
Cell inner membrane | Single-pass membrane protein
Membrane anchored
 
SRP
SEC
 
 
no
yes
MCP3_ECOLI
P05704
trg
b1421 JW1417
Methyl-accepting chemotaxis protein III (MCP-III) (Ribose and galactose chemoreceptor protein)
Integral Inner Membrane
B
IM (predicted), Detected in IM Fraction
Cell inner membrane | Multi-pass membrane protein
Integral Membrane Protein
 
SRP
SEC
 
 
no
yes
FTSQ_ECOLI
P06136
ftsQ
b0093 JW0091
Cell division protein ftsQ
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane | Single-pass type II membrane protein
Membrane anchored
 
SRP
SEC
 
 
yes
yes
PSIE_ECOLI
P0A7C8
psiE

yjbA

b4030 JW3990
Protein psiE
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane | Multi-pass membrane protein
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
TATE_ECOLI
P0A843
tatE

ybeC

b0627 JW0622
Sec-independent protein translocase protein tatE
Integral Inner Membrane
B
IM (predicted), Detected in IM Fraction
Cell inner membrane | Single-pass membrane protein
Membrane anchored
 
SRP
SEC
 
 
yes
yes
YFBV_ECOLI
P0A8D9
yfbV
b2295 JW2292
UPF0208 membrane protein yfbV
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane | Multi-pass membrane protein
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
BTUC_ECOLI
P06609
btuC
b1711 JW1701
Vitamin B12 import system permease protein BtuC
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane | Multi-pass membrane protein
Integral Membrane Protein
 
SRP
YidC
 
 
yes
yes
BIRA_ECOLI
P06709
birA

bioR dhbB

b3973 JW3941
Bifunctional protein BirA [Includes: Biotin operon repressor; Biotin--[acetyl-CoA-carboxylase] synthetase (EC 6.3.4.15) (Biotin--protein ligase)]. Deletion of BioR resulted in a 15-fold increase of bio operon transcription in the presence of high biotin levels.
Nucleoid, Integral Inner Membrane
N, B
IM (predicted)
 
Cytoplasmic
 
SRP
SEC
 
 
yes
yes
FHUB_ECOLI
P06972
fhuB
b0153 JW0149
Iron(3+)-hydroxamate import system permease protein fhuB (Ferric hydroxamate uptake protein B) (Ferrichrome transport system permease protein fhuB) (Ferrichrome uptake protein fhuB) (Iron(III)-hydroxamate import system permease protein fhuB)
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane | Multi-pass membrane protein
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
PNTA_ECOLI
P07001
pntA
b1603 JW1595
NAD(P) transhydrogenase subunit alpha (EC 1.6.1.2) (Nicotinamide nucleotide transhydrogenase subunit alpha) (Pyridine nucleotide transhydrogenase subunit alpha)
Integral Inner Membrane
B
IM (predicted), Detected in IM Fraction
Cell inner membrane | Multi-pass membrane protein
Integral Membrane Protein (Experimental)
 
SRP
SEC
 
 
yes
yes
USPB_ECOLI
P0A8S5
uspB

yhiO

b3494 JW3461
Universal stress protein B
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane | Multi-pass membrane protein
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
ESSD_ECOLI
P0A9R2
essD

ybcR

b0554 JW0543
Lysis protein S homolog from lambdoid prophage DLP12
Integral Inner Membrane
B
IM (predicted)
 
Integral Membrane Protein
 
SRP
SEC
 
 
yes
no
MCP2_ECOLI
P07017
tar

cheM

b1886 JW1875
Methyl-accepting chemotaxis protein II (MCP-II) (Aspartate chemoreceptor protein)
Integral Inner Membrane
B
IM (predicted), Detected in IM Fraction
Cell inner membrane | Multi-pass membrane protein
Integral Membrane Protein (Experimental)
 
SRP
SEC
 
 
yes
yes
MCP4_ECOLI
P07018
tap
b1885 JW1874
Methyl-accepting chemotaxis protein IV (MCP-IV) (Dipeptide chemoreceptor protein)
Integral Inner Membrane
B
IM (predicted), Detected in IM Fraction
Cell inner membrane | Multi-pass membrane protein
Integral Membrane Protein
 
SRP
SEC
 
 
no
yes
PUTP_ECOLI
P07117
putP
b1015 JW1001
Sodium/proline symporter (Proline permease) (Propionate transporter)
Integral Inner Membrane
B
IM (predicted), Detected in IM Fraction
Cell inner membrane | Multi-pass membrane protein
Integral Membrane Protein (Experimental)
 
SRP
SEC
 
 
yes
yes
PSTA_ECOLI
P07654
pstA

phoT

b3726 JW3704
Phosphate transport system permease protein pstA
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane | Multi-pass membrane protein
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
YMCE_ECOLI
P0AAA5
sfa

sfa

b0991 JW0975
Protein sfa
Integral Inner Membrane
B
N/A
Cell membrane | Single-pass membrane protein
Membrane anchored
 
SRP
SEC
 
 
no
yes
YAIY_ECOLI
P0AAP7
yaiY
b0379 JW0370
Inner membrane protein yaiY
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane | Multi-pass membrane protein
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
YAIZ_ECOLI
P0AAQ0
yaiZ
b0380 JW5053
Uncharacterized protein yaiZ
Integral Inner Membrane
B
IM (predicted)
Cell membrane | Multi-pass membrane protein
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
GLPT_ECOLI
P08194
glpT
b2240 JW2234
Glycerol-3-phosphate transporter (G-3-P transporter) (G-3-P permease)
Integral Inner Membrane
B
IM (predicted), Detected in IM Fraction
Cell inner membrane | Multi-pass membrane protein
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
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