STEPdb: Sub-cellular Topologies of E.coli Polypeptides.

View: E.coli K-12 (MG1655) membranome  Export to Excel  Export to HTML  Export to XML  Export to CSV  

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E.coli K-12 (MG1655) membranome

(mouse over and click on the one letter topology symbols to see which proteins of this specific subproteome are localized in each location)

Bacterial cell cartoon of sub-cellular locations


Protein ID
(Uniprot)
Accession
(Uniprot)
Gene Name
(Uniprot)
Order
Locus Name
Protein Name
(STEPdb)
Full Name
Symbol
Uniprot
EchoLOCATION
Extracellular Appendage
First Level
Targeting
Chaperoning
First Level
Secretion
System
Second Level
Targeting
Chaperoning
Second Level
Secretion
System
K-12 Core
Proteome
(yes/no)
K-12 Basic
Proteome
(yes/no)
PTM3C_ECOLI
P00550
mtlA
b3599 JW3573
integral IM protein (SEC in IM), PTS system mannitol-specific EIICBA component MtlA
Integral Inner Membrane
B
IM (predicted), Detected in IM Fraction
Cell inner membrane
Integral Membrane Protein
 
SRP (exp)
SEC
 
 
yes
yes
LEP_ECOLI
P00803
lepB
b2568 JW2552
integral IM protein (SEC-YidC in IM), Signal peptidase I LepB
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane
Integral Membrane Protein
 
 
SEC-YidC
 
 
yes
yes
LSPA_ECOLI
P00804
lspA

lsp

b0027 JW0025
integral IM protein (SEC in IM), Signal peptidase II LspA
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
MALF_ECOLI
P02916
malF
b4033 JW3993
integral IM protein (SEC in IM), Maltose/maltodextrin transport system permease MalF
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane
Integral Membrane Protein
 
SRP (exp)
SEC
YfgM
 
no
yes
PBPA_ECOLI
P02918
mrcA

ponA

b3396 JW3359
integral IM protein (SEC in IM), Penicillin-binding 1A MrcA
Integral Inner Membrane
B
Soluble IM Fraction
Cell inner membrane
Membrane anchored (Experimental)
 
SRP
SEC
 
 
yes
yes
GSPB_ECOLI
P03825
gspB

pinO pioO pno

b3322 JW3284
integral IM protein (SEC in IM), Putative general secretion pathway B GspB
Integral Inner Membrane
B
IM (predicted)
Cell membrane
Membrane anchored
 
SRP
SEC
 
 
no
yes
PBPB_ECOLI
P02919
mrcB

pbpF ponB

b0149 JW0145
integral IM protein (SEC in IM), Penicillin-binding 1B MrcB
Integral Inner Membrane
B
IM (predicted), Detected in IM Fraction
Cell inner membrane; Single-pass type II membrane protein
Membrane anchored
 
SRP
SEC
 
 
yes
yes
LACY_ECOLI
P02920
lacY
b0343 JW0334
integral IM protein (SEC in IM), Lactose permease LacY
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
MELB_ECOLI
P02921
melB

mel-4

b4120 JW4081
integral IM protein (SEC in IM), Melibiose carrier MelB
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane
Integral Membrane Protein
 
SRP
SEC
 
 
no
yes
PPDB_ECOLI
P08371
ppdB

ygdC

b2825 JW5451
integral IM protein (SEC in IM), Prepilin peptidase-dependent B PpdB
Integral Inner Membrane
B
IM (predicted)
 
Membrane anchored
 
SRP
SEC
 
 
yes
yes
PPDC_ECOLI
P08372
ppdC

ygdA

b2823 JW2791
integral IM protein (SEC in IM), Prepilin peptidase-dependent C PpdC
Integral Inner Membrane
B
IM (predicted)
 
Membrane anchored
 
SRP
SEC
 
 
yes
yes
FTSB_ECOLI
P0A6S5
ftsB

ygbQ

b2748 JW2718
integral IM protein (SEC in IM), Cell division FtsB
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane
Membrane anchored
 
SRP
SEC
 
 
yes
yes
TONB_ECOLI
P02929
tonB

exbA

b1252 JW5195
integral IM protein (SEC in IM), TonB
Integral Inner Membrane
B
N/A
Cell inner membrane; Single-pass membrane protein; Periplasmic side
Membrane anchored
 
 
SEC
 
 
yes
yes
MCP1_ECOLI
P02942
tsr

cheD

b4355 JW4318
integral IM protein (SEC in IM), Methyl-accepting chemotaxis I Tsr
Integral Inner Membrane
B
IM (predicted), Detected in IM Fraction
Cell inner membrane
Integral Membrane Protein
 
SRP
SEC
 
 
no
yes
KEFC_ECOLI
P03819
kefC

trkC

b0047 JW0046
integral IM protein (SEC in IM), Glutathione-regulated potassium-efflux system KefC
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
KDPA_ECOLI
P03959
kdpA
b0698 JW0686
integral IM protein (SEC in IM), Potassium-transporting ATPase potassium-binding subunit KdpA
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane
Integral Membrane Protein
 
SRP
SEC
 
 
no
yes
PSIE_ECOLI
P0A7C8
psiE

yjbA

b4030 JW3990
integral IM protein (SEC in IM), PsiE
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane; Multi-pass membrane protein
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
YFBV_ECOLI
P0A8D9
yfbV
b2295 JW2292
integral IM protein (SEC in IM), UPF0208 YfbV
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane; Multi-pass membrane protein
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
USPB_ECOLI
P0A8S5
uspB

yhiO

b3494 JW3461
integral IM protein (SEC in IM), Universal stress B UspB
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane; Multi-pass membrane protein
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
KDPB_ECOLI
P03960
kdpB
b0697 JW0685
integral IM protein (SEC in IM), Potassium-transporting ATPase ATP-binding subunit KdpB
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
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 ©2017 Copyright KU Leuven and FORTH/ICE-HT. Last Update: February 2019.