STEPdb: Sub-cellular Topologies of E.coli Polypeptides.

View: E.coli K-12 (MG1655) membranome  Export to Excel  Export to HTML  Export to XML  Export to CSV  

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E.coli K-12 (MG1655) membranome

(mouse over and click on the one letter topology symbols to see which proteins of this specific subproteome are localized in each location)

Bacterial cell cartoon of sub-cellular locations


Protein ID
(Uniprot)
Accession
(Uniprot)
Gene Name
(Uniprot)
Order
Locus Name
Protein Name
(STEPdb)
Full Name
Symbol
Uniprot
EchoLOCATION
Extracellular Appendage
First Level
Targeting
Chaperoning
First Level
Secretion
System
Second Level
Targeting
Chaperoning
Second Level
Secretion
System
K-12 Core
Proteome
(yes/no)
K-12 Basic
Proteome
(yes/no)
DEDD_ECOLI
P09549
dedD
b2314 JW5378
integral IM protein (SEC in IM), Cell division DedD
Integral Inner Membrane
B
IM (predicted), Detected in IM Fraction
Cell inner membrane
Membrane anchored
 
SRP
SEC
 
 
yes
yes
UHPB_ECOLI
P09835
uhpB
b3668 JW3643
integral IM protein (SEC in IM), Signal transduction histidine-kinase/phosphatase UhpB
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
UHPC_ECOLI
P09836
uhpC
b3667 JW3642
integral IM protein (SEC in IM), sensor UhpC
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
UBIB_ECOLI
P0A6A0
ubiB

aarF yigQ yigR yigS

b3835 JW3812
integral IM protein (SEC in IM), Probable kinase UbiB
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
FLIL_ECOLI
P0ABX8
fliL

cheC1 fla AI fla QI

b1944 JW1928
integral IM protein (SEC in IM), FliL
Integral Inner Membrane
B
Soluble IM Fraction
Cell inner membrane
Outer membrane Lipoprotein
 
SRP
SEC
 
 
no
yes
FLIQ_ECOLI
P0AC07
fliQ

flaQ

b1949 JW1933
Flagellar integral IM protein (SEC in IM), biosynthetic FliQ
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane
Integral Membrane Protein
flagellum
SRP
SEC
 
 
no
yes
YEAL_ECOLI
P0ACY6
yeaL
b1789 JW1778
integral IM protein (SEC in IM), UPF0756 YeaL
Integral Inner Membrane
B
IM (predicted)
Cell membrane
Integral Membrane Protein
 
SRP
SEC
 
 
no
yes
YOHC_ECOLI
P0AD17
yohC
b2135 JW5356
integral IM protein (SEC in IM), YohC
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane; Multi-pass membrane protein
Integral Membrane Protein (Experimental)
 
SRP
SEC
 
 
yes
yes
CLSA_ECOLI
P0A6H8
clsA

cls nov yciJ

b1249 JW1241
integral IM protein (SEC in IM), Cardiolipin synthase A ClsA
Integral Inner Membrane
B
IM (predicted), Detected in IM Fraction
Cell inner membrane
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
CYSZ_ECOLI
P0A6J3
cysZ
b2413 JW2406
integral IM protein (SEC-YidC in IM), Sulfate transporter CysZ
Integral Inner Membrane
B
IM (predicted), Detected in IM Fraction
Cell inner membrane
Integral Membrane Protein (Experimental)
 
SRP
SEC-YidC
 
 
yes
yes
DSBB_ECOLI
P0A6M2
dsbB

roxB ycgA

b1185 JW5182
integral IM protein (SEC-YidC in IM), Disulfide bond formation B DsbB
Integral Inner Membrane
B
IM (predicted), Detected in IM Fraction
Cell inner membrane
Integral Membrane Protein
 
SRP
SEC-YidC
 
 
yes
yes
MRAY_ECOLI
P0A6W3
mraY

murX

b0087 JW0085
integral IM protein (SEC in IM), Phospho-N-acetylmuramoyl-pentapeptide-transferase MraY
Integral Inner Membrane
B
IM (predicted), Detected in IM Fraction
Cell inner membrane
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
YPHA_ECOLI
P0AD47
yphA
b2543 JW2527
integral IM protein (SEC in IM), YphA
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane; Multi-pass membrane protein
Integral Membrane Protein (Experimental)
 
SRP
SEC
 
 
yes
yes
YJJB_ECOLI
P0ADD2
yjjB
b4363 JW4327
integral IM protein (SEC in IM), UPF0442 YjjB
Integral Inner Membrane
B
IM (predicted)
Cell membrane
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
YHHN_ECOLI
P0ADI9
yhhN
b3468 JW3433
integral IM protein (SEC in IM), YhhN
Integral Inner Membrane
B
IM (predicted)
Cell membrane
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
YCIB_ECOLI
P0A710
yciB

ispZ

b1254 JW1246
integral IM protein (SEC in IM), Probable intracellular septation A YciB
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane; Multi-pass membrane protein
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
KDGT_ECOLI
P0A712
kdgT
b3909 JW5560
integral IM protein (SEC in IM), 2-keto-3-deoxygluconate permease KdgT
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane; Multi-pass membrane protein
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
MSCL_ECOLI
P0A742
mscL

yhdC

b3291 JW3252
integral IM protein (YidC in IM), Large-conductance mechanosensitive channel MscL
Integral Inner Membrane
B
IM (predicted), Detected in IM Fraction
Cell inner membrane
Integral Membrane Protein (Experimental)
 
SRP
YidC
 
 
yes
yes
RSXA_ECOLI
P0A766
rsxA

rnfA ydgL

b1627 JW1619
integral IM protein (SEC in IM), Ion-translocating oxidoreductase complex subunit A RsxA
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane
Integral Membrane Protein(experimental)
 
SRP
SEC
 
 
yes
yes
MNTH_ECOLI
P0A769
mntH

yfeP

b2392 JW2388
integral IM protein (SEC in IM), Divalent metal cation transporter MntH
Integral Inner Membrane
B
IM (predicted)
Cell inner membrane
Integral Membrane Protein (Experimental)
 
SRP
SEC
 
 
yes
yes
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