STEPdb: Sub-cellular Topologies of E.coli Polypeptides.

View: Proteins with multiple sub-cellular topologies in E.coli K-12 (MG1655)  Export to Excel  Export to CSV  

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Proteins with multiple sub-cellular topologies in E.coli K-12 (MG1655)

(mouse over and click on the one letter topology symbols to see which proteins of this specific subproteome are localized in each location)

Bacterial cell cartoon of sub-cellular locations


Protein ID
(Uniprot)
Accession
(Uniprot)
Gene Name
(Uniprot)
Order
Locus Name
Protein Name
(STEPdb)
Full Name
Symbol
Uniprot
EchoLOCATION
Extracellular Appendage
First Level
Targeting
Chaperoning
First Level
Secretion
System
Second Level
Targeting
Chaperoning
Second Level
Secretion
System
K-12 Core
Proteome
(yes/no)
K-12 Basic
Proteome
(yes/no)
MUKB_ECOLI
P22523
mukB
b0924 JW0907
cytoplasmic nucleoid peripheral IM protein, Chromosome partition MukB
Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm
A, N, F1
N/A
Cytoplasm; nucleoid
Cytoplasmic
 
 
 
 
 
yes
yes
MUKE_ECOLI
P22524
mukE

kicA ycbA

b0923 JW0906
cytoplasmic nucleoid peripheral IM protein, Chromosome partition MukE
Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm
A, N, F1
N/A
Cytoplasm; nucleoid
Cytoplasmic
 
 
 
 
 
yes
yes
FECI_ECOLI
P23484
fecI
b4293 JW4253
cytoplasmic nucleoid peripheral IM protein, Probable RNA polymerase sigma factor FecI
Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm
A, N, F1
N/A
 
Cytoplasmic
 
 
 
 
 
no
yes
CADC_ECOLI
P23890
cadC
b4133 JW4094
nucleoid & integral IM protein (SEC in IM), Transcriptional activator CadC
Integral Inner Membrane, Nucleoid
B, N
IM (predicted)
Cell membrane
Membrane anchored
 
SRP
SEC
 
 
no
yes
RADA_ECOLI
P24554
radA

sms

b4389 JW4352
cytoplasmic nucleoid peripheral IM protein, DNA repair RadA
Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm
A, N, F1
N/A
 
Cytoplasmic
 
 
 
 
 
yes
yes
NADR_ECOLI
P27278
nadR

nadI

b4390 JW5800
cytoplasmic nucleoid peripheral IM protein, Trifunctional NAD biosynthesis/regulator NadR
Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm
A, N, F1
N/A
Cell membrane; Peripheral membrane protein Cytoplasm
Cytoplasmic
 
 
 
 
 
yes
yes
RODZ_ECOLI
P27434
rodZ

yfgA

b2516 JW2500
nucleoid & integral IM protein (SEC in IM), Cytoskeleton RodZ
Integral Inner Membrane, Nucleoid
B, N
IM (predicted)
Cell inner membrane
Membrane anchored
 
 
SEC
 
 
yes
yes
RNB_ECOLI
P30850
rnb
b1286 JW1279
cytoplasmic nucleoid peripheral IM protein, Exoribonuclease 2 Rnb
Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm
A, N, F1
N/A
Cytoplasm
Cytoplasmic
 
 
 
 
 
yes
yes
MLRA_ECOLI
P33358
mlrA

yehV

b2127 JW2115
cytoplasmic nucleoid peripheral IM protein, HTH-type transcriptional regulator MlrA
Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm
A, N, F1
IM (predicted)
 
Cytoplasmic
 
 
 
 
 
yes
yes
RSGA_ECOLI
P39286
rsgA

engC yjeQ

b4161 JW4122
ribosomal cytoplasmic peripheral IM protein, Small ribosomal subunit biogenesis GTPase RsgA
Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm, ribosomal
A, F1, r
N/A
Cytoplasm
Cytoplasmic
ribosome
 
 
 
 
yes
yes
YGJI_ECOLI
P42590
ygjI
b3078 JW5512
nucleoid & integral IM protein (SEC in IM), transporter YgjI
Integral Inner Membrane, Nucleoid
B, N
IM (predicted)
Cell inner membrane; Multi-pass membrane protein
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
XAPB_ECOLI
P45562
xapB
b2406 JW2397
nucleoid & integral IM protein (SEC in IM), Xanthosine permease XapB
Integral Inner Membrane, Nucleoid
B, N
IM (predicted)
Cell inner membrane
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
FTSK_ECOLI
P46889
ftsK
b0890 JW0873
nucleoid & integral IM protein (SEC in IM), DNA translocase FtsK
Integral Inner Membrane, Nucleoid
B, N
IM (predicted)
Cell inner membrane
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
MLC_ECOLI
P50456
mlc
b1594 JW1586
cytoplasmic nucleoid peripheral IM protein, Mlc
Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm
A, N, F1
IM (predicted)
 
Cytoplasmic
 
 
 
 
 
yes
yes
CSGD_ECOLI
P52106
csgD
b1040 JW1023
cytoplasmic nucleoid peripheral IM protein, CsgBAC operon transcriptional regulatory protein CsgD
Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm
A, N, F1
N/A
Cell inner membrane
Cytoplasmic
 
 
 
 
 
yes
yes
FLIK_ECOLI
P52614
fliK

flaE flaR

b1943 JW1927
Flagellar cytoplasmic & extra-cellular protein (Flagellum secreted), hook-length control protein FliK
Cytoplasmic, Extra-cellular
A, X
N/A
 
Cytoplasmic
flagellum
 
Flagellum
 
Fla
no
yes
YBHD_ECOLI
P52696
ybhD
b0768 JW5896
nucleoid & integral IM protein (SEC in IM), HTH-type transcriptional regulator YbhD
Integral Inner Membrane, Nucleoid
B, N
N/A
 
Membrane anchored
 
SRP
SEC
 
 
no
yes
MUKF_ECOLI
P60293
mukF

kicB

b0922 JW0905
cytoplasmic nucleoid peripheral IM protein, Chromosome partition MukF
Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm
A, N, F1
N/A
Cytoplasm; nucleoid
Cytoplasmic
 
 
 
 
 
yes
yes
SECM_ECOLI
P62395
secM

srrA yacA

b0097 JW5007
cytoplasmic & periplasmic protein (SEC through IM), Secretion monitor SecM
Cytoplasmic, Periplasmic
A, G
N/A
Cytoplasm; cytosol
Periplasmic (Experimental)
 
 
SEC
SURA
 
yes
yes
AAER_ECOLI
P67662
aaeR

yhcS

b3243 JW3212
nucleoid & integral IM protein (SEC in IM), HTH-type transcriptional activator AaeR
Integral Inner Membrane, Nucleoid
B, N
IM (predicted)
 
Cytoplasmic
 
SRP
SEC
 
 
yes
yes
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