STEPdb: Sub-cellular Topologies of E.coli Polypeptides.

View: Proteins with multiple sub-cellular topologies in E.coli K-12 (MG1655)  Export to Excel  Export to CSV  

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Proteins with multiple sub-cellular topologies in E.coli K-12 (MG1655)

(mouse over and click on the one letter topology symbols to see which proteins of this specific subproteome are localized in each location)

Bacterial cell cartoon of sub-cellular locations


Protein ID
(Uniprot)
Accession
(Uniprot)
Gene Name
(Uniprot)
Order
Locus Name
Protein Name
(Uniprot)
Full Name
Symbol
Uniprot
EchoLOCATION
Extracellular Appendage
First Level
Targeting
Chaperoning
First Level
Secretion
System
Second Level
Targeting
Chaperoning
Second Level
Secretion
System
K-12 Core
Proteome
(yes/no)
K-12 Basic
Proteome
(yes/no)
SECM_ECOLI
P62395
secM

srrA yacA

b0097 JW5007
Secretion monitor
Cytoplasmic, Periplasmic
A, G
N/A
Cytoplasm cytosolPeriplasm
Periplasmic (Experimental)
 
 
SEC
SURA
 
yes
yes
YQJD_ECOLI
P64581
yqjD
b3098 JW3069
Uncharacterized protein yqjD
Integral Inner Membrane, ribosomal
B, r
IM (predicted), Detected in IM Fraction
 
Membrane anchored
 
SRP
SEC
 
 
no
yes
AAER_ECOLI
P67662
aaeR

yhcS

b3243 JW3212
HTH-type transcriptional activator AaeR
Nucleoid, Integral Inner Membrane
N, B
IM (predicted)
 
Cytoplasmic
 
SRP
SEC
 
 
yes
yes
LPP_ECOLI
P69776
lpp

mlpA mulI

b1677 JW1667
Major outer membrane lipoprotein Lpp (Braun lipoprotein) (Murein-lipoprotein)
Outer Membrane Lipoprotein, Peripheral outer membrane protein facing the extra-cellular space
I, F4
Soluble IM Fraction
Cell outer membrane | Lipid-anchorCell outer membrane | Peptidoglycan-anchor
Outer membrane Lipoprotein (Experimental)
 
TF
SEC
 
LOL
yes
yes
CLCB_ECOLI
P76175
clcB

mriT ynfJ

b1592 JW5263
Voltage-gated ClC-type chloride channel ClcB
Nucleoid, Integral Inner Membrane
N, B
IM (predicted)
Cell inner membrane | Multi-pass membrane protein.
Integral Membrane Protein
 
SRP
SEC
 
 
yes
yes
HLYE_ECOLI
P77335
hlyE

clyA hpr sheA ycgD

b1182 JW5181
Hemolysin E, chromosomal (Cytotoxin ClyA) (Hemolysis-inducing protein) (Latent pore-forming 34 kDa hemolysin) (Silent hemolysin SheA)
Periplasmic, Extra-cellular
G, X
N/A
SecretedPeriplasmHost cell membrane | Single-pass membrane protein
Secreted and released (Experimental)
 
 
Uknown mechanism
 
OMV
no
yes
YQEI_ECOLI
Q46942
yqeI
b2847 JW2815
Uncharacterized J domain-containing protein djlB
Nucleoid, Integral Inner Membrane
N, B
IM (predicted)
 
Cytoplasmic
 
SRP
SEC
 
 
no
yes
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