STEPdb: Sub-cellular Topologies of E.coli Polypeptides.

View: E.coli K-12 (MG1655) Sec secretome  Export to Excel  Export to HTML  Export to XML  Export to CSV  

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E.coli K-12 (MG1655) Sec secretome

(mouse over and click on the one letter topology symbols to see which proteins of this specific subproteome are localized in each location)

Bacterial cell cartoon of sub-cellular locations


Protein ID
(Uniprot)
Accession
(Uniprot)
Gene Name
(Uniprot)
Order
Locus Name
Protein Name
(STEPdb)
Full Name
Symbol
Uniprot
EchoLOCATION
Extracellular Appendage
First Level
Targeting
Chaperoning
First Level
Secretion
System
Second Level
Targeting
Chaperoning
Second Level
Secretion
System
K-12 Core
Proteome
(yes/no)
K-12 Basic
Proteome
(yes/no)
MLTF_ECOLI
P0AGC5
mltF

yfhD

b2558 JW2542
periplasmic peripheral OM protein (SEC through IM), Membrane-bound lytic murein transglycosylase F MltF
Peripheral outer membrane protein facing the periplasm
F3
N/A
Cell outer membrane
Periplasmic
 
 
SEC
 
 
no
yes
SODC_ECOLI
P0AGD1
sodC
b1646 JW1638
periplasmic protein (SEC through IM), Superoxide dismutase SodC
Periplasmic
G
N/A
Periplasm
Periplasmic (Experimental)
 
 
SEC
 
 
yes
yes
YEGJ_ECOLI
P76394
yegJ
b2071 JW2056
periplasmic protein (SEC through IM), YegJ
Periplasmic
G
N/A
 
Periplasmic
 
 
SEC
 
 
no
yes
YEGR_ECOLI
P76406
yegR
b2085 JW5837
OM lipoprotein (SEC through IM, inserted in OM by LOL), YegR
Outer Membrane Lipoprotein
I
N/A
 
Outer membrane Lipoprotein
 
 
SEC
 
LOL
yes
yes
YFAT_ECOLI
P76466
yfaT
b2229 JW2223
periplasmic protein (SEC through IM), YfaT
Periplasmic
G
N/A
 
Periplasmic
 
 
SEC
 
 
no
yes
YFDX_ECOLI
P76520
yfdX
b2375 JW2372
periplasmic protein (SEC through IM), YfdX
Periplasmic
G
N/A
 
Periplasmic (Experimental)
 
 
SEC
 
 
yes
yes
MLTC_ECOLI
P0C066
mltC

yggZ

b2963 JW5481
OM lipoprotein (SEC through IM), inserted in OM by LOL), Membrane-bound lytic murein transglycosylase C MltC
Outer Membrane Lipoprotein
I
N/A
Cell outer membrane
Outer membrane Lipoprotein (Experimental)
 
 
SEC
 
LOL
yes
yes
MEPA_ECOLI
P0C0T5
mepA
b2328 JW2325
periplasmic protein (SEC through IM), Penicillin-insensitive murein endopeptidase MepA
Periplasmic
G
N/A
Periplasm
Periplasmic (Experimental)
 
 
SEC
DSBA,DSBC
 
yes
yes
DEGP_ECOLI
P0C0V0
degP

htrA ptd

b0161 JW0157
periplasmic protein (SEC through IM), serine endoprotease DegP
Periplasmic
G
N/A
Cell inner membrane
Periplasmic (Experimental)
 
SECB
SEC
DSBA
 
yes
yes
EMTA_ECOLI
P0C960
emtA

mltE sltZ ycgP

b1193 JW5821
OM lipoprotein (SEC through IM), inserted in OM by LOL), Endo-type membrane-bound lytic murein transglycosylase A EmtA
Outer Membrane Lipoprotein
I
N/A
Cell outer membrane
Outer membrane Lipoprotein (Experimental)
 
 
SEC
 
LOL
yes
yes
YFFQ_ECOLI
P76548
yffQ
b2448
periplasmic protein (SEC through IM), YffQ
Periplasmic
G
N/A
 
Periplasmic
 
 
SEC
 
 
no
no
YFGI_ECOLI
P76573
yfgI
b2506 JW2490
periplasmic protein (SEC through IM), YfgI
Periplasmic
G
N/A
 
Periplasmic
 
 
SEC
 
 
no
yes
YKFB_ECOLI
P77162
ykfB
b0250 JW0239
periplasmic protein (SEC through IM), YkfB
Periplasmic
G
N/A
 
Periplasmic
 
 
SEC
 
 
no
no
ACFD_ECOLI
P0CK95
yghJ
b4466 JW5925 ECK2968
IM lipoprotein (SEC through IM), inserted in OM by LOL), Putative AcfD homolog YghJ
Inner Membrane Lipoprotein
E
N/A
Cell membrane
Inner membrane lipoprotein
 
 
SEC
 
LOL
no
yes
RLPA_ECOLI
P10100
rlpA
b0633 JW0628
OM lipoprotein (SEC through IM), inserted in OM by LOL), Endolytic PG transglycosylase RlpA RlpA
Outer Membrane Lipoprotein
I
N/A
Cell membrane
Outer membrane Lipoprotein (Experimental)
 
 
SEC
 
LOL
yes
yes
FADL_ECOLI
P10384
fadL

ttr

b2344 JW2341
OM b-barrel protein (SEC through IM, inserted in OM by BAM), Long-chain fatty acid transport FadL
Outer Membrane b-barrel protein
H
N/A
Cell outer membrane
Outer Membrane ??-barrel protein (Experimental)
 
 
SEC
SURA,SKP
BAM
yes
yes
CUSF_ECOLI
P77214
cusF

cusX ylcC

b0573 JW0562
periplasmic protein (SEC through IM), Cation efflux system CusF
Periplasmic
G
N/A
Periplasm
Periplasmic (Experimental)
 
 
SEC
 
 
yes
yes
YDDL_ECOLI
P77519
yddL
b1472 JW1468
OM b-barrel protein (SEC through IM), YddL
Outer Membrane b-barrel protein
H
N/A
 
Periplasmic
 
 
SEC
 
 
yes
yes
YSAB_ECOLI
Q2M7M3
ysaB
b4553 JW3532
OM lipoprotein (SEC through IM, inserted in OM by LOL), YsaB
Outer Membrane Lipoprotein
I
N/A
Cell membrane
Outer membrane Lipoprotein
 
 
SEC
 
LOL
yes
yes
IAP_ECOLI
P10423
iap
b2753 JW2723
periplasmic peripheral IM protein (SEC through IM), Alkaline phosphatase isozyme conversion Iap
Peripheral inner membrane protein facing the periplasm
F2
N/A
 
Membrane associated (Experimental)
 
 
SEC
 
 
yes
yes
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