E.coli K-12 (MG1655) Sec Secretome

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Nucleoid Cytoplasmic Peripheral inner membrane protein facing the cytoplasm Integral inner membrane Ribosomal Inner membrane lipoprotein Peripheral inner membrane protein facing the periplasm Periplasmic Peripheral outer membrane protein facing the periplasm Outer membrane β-barrel protein Peripheral outer membrane protein facing the extra-cellular space Extra-cellular Outer membrane lipoprotein

Protein Information Subcellular Localization Targeting/Export System
Protein ID /
Accession #
(UniProt)
Gene Name
(UniProt)
Protein Name
(UniProt)
Order
Locus Name
Protein Name
(STEPdb)
Reference structure
Topology Class
Full name
(STEPdb)
Symbol
(STEPdb)
Topology Class
UniProt
Extracellular Appendage First Level
Targeting
Chaperoning
First Level
Secretion
System
Second Level
Targeting
Chaperoning
Second Level
Secretion
System
K-12 Core
Proteome
(yes/no)
K-12 Basic
Proteome
(yes/no)
YMGJ_ECOLI
A5A612
ymgJ Uncharacterized protein YmgJ b4594 periplasmic protein (SEC through IM), YmgJ ab initio Zhang model E10797 (score: 0.515) Periplasmic G - - - SEC - - no yes
YJBT_ECOLI
A5A628
yjbT Uncharacterized protein YjbT b4620 periplasmic protein (SEC through IM), YjbT ab initio Zhang model E10740 (score: 0.458) Periplasmic G - - - SEC - - no yes
RZOQ_ECOLI
C1P601
rzoQ Putative lipoprotein RzoQ b4689 JW1545.1 IM lipoprotein (SEC through IM), inserted in OM by LOL), Putative RzoQ ab initio Zhang model E10367 (score: 0.604) Inner Membrane Lipoprotein E Cell membrane - - SEC - LOL no yes
YPDI_ECOLI
O32528
ypdI Uncharacterized lipoprotein YpdI b2376 JW2373 OM lipoprotein (SEC through IM, inserted in OM by LOL), YpdI SWISS-MODEL named O32528 (score: 0.5148481172) Outer Membrane Lipoprotein I Cell membrane - - SEC - LOL no yes
YFJS_ECOLI
O52982
yfjS Lipoprotein YfjS b2636 JW5921 IM lipoprotein (SEC through IM, inserted in OM by LOL), YfjS SWISS-MODEL named O52982 (score: 0.6690054512) Inner Membrane Lipoprotein E Cell inner membrane - - SEC - LOL no no
PPB_ECOLI
P00634
phoA Alkaline phosphatase (APase) (EC 3.1.3.1) b0383 JW0374 periplasmic protein (SEC through IM), Alkaline phosphatase PhoA 1y6v PDB ID, chain A, for protein P00634 Periplasmic G Periplasm - - SEC DSBA - no yes
ASPG2_ECOLI
P00805
ansB L-asparaginase 2 (EC 3.5.1.1) (L-asparaginase II) (L-ASNase II) (L-asparagine amidohydrolase II) (Colaspase) b2957 JW2924 periplasmic protein (SEC through IM), L-asparaginase 2 AnsB 5mq5 PDB ID, chain B, for protein P00805 Periplasmic G Periplasm - - SEC - - yes yes
AMPC_ECOLI
P00811
ampC Beta-lactamase (EC 3.5.2.6) (Cephalosporinase) b4150 JW4111 periplasmic protein (SEC through IM), Beta-lactamase AmpC 2ffy PDB ID, chain A, for protein P00811 Periplasmic G Periplasm - - SEC - - yes yes
ARAF_ECOLI
P02924
araF L-arabinose-binding periplasmic protein (ABP) b1901 JW1889 periplasmic protein (SEC through IM), L-arabinose-binding periplasmic AraF 8abp PDB ID, chain A, for protein P02924 Periplasmic G Periplasm - - SEC - - yes yes
RBSB_ECOLI
P02925
rbsB Ribose import binding protein RbsB b3751 JW3730 periplasmic protein (SEC through IM), Ribose import binding RbsB 2dri PDB ID, chain A, for protein P02925 Periplasmic G Periplasm - - SEC SKP - no yes
TOLC_ECOLI
P02930
tolC Outer membrane protein TolC (Multidrug efflux pump subunit TolC) (Outer membrane factor TolC) b3035 JW5503 OM b-barrel protein (SEC through IM, inserted in OM by BAM), TolC 1tqq PDB ID, chain A, for protein P02930 Outer Membrane b-barrel protein H Cell outer membrane - SECB SEC SKP BAM yes yes
OMPF_ECOLI
P02931
ompF Outer membrane protein F (Outer membrane protein 1A) (Outer membrane protein B) (Outer membrane protein IA) (Porin OmpF) b0929 JW0912 OM b-barrel protein (SEC through IM, inserted in OM by BAM), OmpF 3poq PDB ID, chain A, for protein P02931 Outer Membrane b-barrel protein H Cell outer membrane - TF SEC SKP, SURA BAM yes yes
PHOE_ECOLI
P02932
phoE Outer membrane pore protein E b0241 JW0231 OM b-barrel protein (SEC through IM, inserted in OM by BAM), PhoE 1pho PDB ID, chain A, for protein P02932 Outer Membrane b-barrel protein H Cell outer membrane, Multi-pass membrane protein - - SEC - BAM yes yes
LAMB_ECOLI
P02943
lamB Maltoporin (Lambda receptor protein) (Maltose-inducible porin) b4036 JW3996 OM b-barrel protein (SEC through IM, inserted in OM by BAM), Maltoporin LamB 1af6 PDB ID, chain A, for protein P02943 Outer Membrane b-barrel protein H Cell outer membrane - - SEC DEGP, SKP, SURA BAM yes yes
MALM_ECOLI
P03841
malM Maltose operon periplasmic protein b4037 JW3997 periplasmic protein (SEC through IM), Maltose operon periplasmic protein MalM ab initio Zhang model E12092 (score: 0.39) Periplasmic G Periplasm - - SEC - - yes yes
FIMA1_ECOLI
P04128
fimA Type-1 fimbrial protein, A chain (Type-1A pilin) b4314 JW4277 Fimbrial extra-cellular peripheral OM protein (SEC through IM, chaperone usher export system over OM), Type-1 protein, A chain FimA 2m5g PDB ID, chain A, for protein P04128 Peripheral outer membrane protein facing the extra-cellular space F4 Fimbrium fimbriae - SEC - CU yes yes
LIVK_ECOLI
P04816
livK Leucine-specific-binding protein (L-BP) (LS-BP) b3458 JW3423 periplasmic protein (SEC through IM), Leucine-specific-binding LivK 2lbp PDB ID, chain A, for protein P04816 Periplasmic G Periplasm - - SEC DSBA - yes yes
NLPA_ECOLI
P04846
nlpA Lipoprotein 28 b3661 JW3635 IM lipoprotein (SEC through IM, inserted in OM by LOL), NlpA TBM Zhang model E12340 (score: 0.873) Inner Membrane Lipoprotein E Cell inner membrane, Lipid-anchor - - SEC - LOL yes yes
PTRA_ECOLI
P05458
ptrA Protease 3 (EC 3.4.24.55) (Pitrilysin) (Protease III) (Protease pi) b2821 JW2789 periplasmic protein (SEC through IM), Protease 3 PtrA 1q2l PDB ID, chain A, for protein P05458 Periplasmic G Periplasm - - SEC SURA - yes yes
FEPA_ECOLI
P05825
fepA Ferrienterobactin receptor (Enterobactin outer-membrane receptor) b0584 JW5086 OM b-barrel protein (SEC through IM, inserted in OM by BAM), Ferrienterobactin receptor FepA 1fep PDB ID, chain A, for protein P05825 Outer Membrane b-barrel protein H Cell outer membrane, Multi-pass membrane protein - - SEC SKP BAM yes yes
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