Homologous proteins of type three secretion system (T3SS) in pathogens and the flagellum

		T3SS in pathogenic bacteria													Flagellar T3SS
		Mammalian pathogensss								Plant pathogens
Structural sub assembly of injectisome	Subunit function/role	Common name	EPEC	P. aeruginosa T3SS	Yersinia T3SS	Shigella flexneri	Salmonella sp. SPI 1	Salmonella enterica SPI 2	Chlamydia pneumoniae	Bordetella	P. syringae	R. solanacearum	Xanthomonas spp.	B. pseudomallei T3SS3	Yersinia Pestis	F1F0 ATPase
Search.. Close Accessory enzyme Assembly regulators ATPase complex Chaperones Cytoplasmic ring Export apparatus or Translocase Gatekeeper IM ring Needle OM-IM connector OM ring Transcription regulators Translocators None	Search.. Close Central stalk**, inserting in ATPase ring Component of 6 Pod assembly Connector of Pods with SctD External stator** connecting ATPase and Cytoplasmic ring For early substrates For early substrates (needle component) For flagellar substrate (FlgK) For flagellar substrate (FliC) For flagellar substrate (FliD) For late substrates (effectors) For middle substrates (filament component) For middle substrates (translocators) Gatekeeper/Affinity switch Global Regulator Hexameric ring-structure ATPase Inner rod Lipoprotein ring component Major component, external to channel Major IM ring component Minor component, external to channel Molecular ruler regulating needle/filament length Muramidase Needle component Pilotin Secretin Subunit 1 of SctW chaperone heterodimer Subunit 2 of SctW chaperone heterodimer Tip/filament protein Translocase channel Translocon pore protein	Search.. Close SctA SctB SctC SctD SctE SctF SctI SctJ SctK SctL SctN SctO SctP SctQ SctR SctS SctT SctU SctV SctW None		Search.. Close ExsB PcrD PcrH PcrV PopB PopD PopN PscC PscD PscE PscF PscG PscI PscJ PscK PscL PscN PscO PscP PscQ PscR PscS PscT PscU None	Search.. Close LcrV SycD SycE VirG YopB YopD YopN +TyeA YsaH YsaK YscC YscD YscE YscF YscG YscI YscJ YscK YscL YscN YscO YscP YscQ YscR YscS YscT YscU YscV (LcrD) None	Search.. Close IpaB IpaC IpaD IpgC IpgF MxiA MxiC MxiD MxiG MxiH MxiI MxiJ MxiK MxiM MxiN Spa13 Spa15 Spa24 Spa29 Spa32 Spa33 Spa40 Spa47 Spa9 None	Search.. Close IagB InvA InvB InvC/SpaL InvE InvG InvH InvI InvJ InvL/SpaP InvN/SpaR OrgA OrgB PrgH PrgI PrgJ PrgK SicA SigE SipB SipC SipD SpaO SpaQ SpaS None	Search.. Close IagB SpiC SsaC SsaD SsaG SsaI SsaJ SsaK SsaL SsaN SsaO SsaP SsaQ SsaR SsaS SsaT SsaU SsaV SseC SseD None	Search.. Close CdsC CdsD CdsF CdsJ CdsL CdsN CdsO CdsP CdsQ CdsR CdsS CdsT CdsU CdsV CopB1/2 CopD1/2 CopN CT584 or LcrV None	Search.. Close BopB BopD BopN BscC BscD BscF BscI BscJ BscK BscL BscN BscQ BscR BscS BscT BscU BscV BscW Bsp22 Btc22 Scc2/Scc3 None	Search.. Close HrcC HrcE HrcJ HrcN HrcQA+B HrcR HrcS HrcT HrcU HrcV HrpA HrpB HrpD HrpG HrpH HrpJ HrpK HrpO HrpP HrpQ HrpV None	Search.. Close HpaA HpaP HrcC HrcD, HrpW HrcJ HrcN HrcQ HrcR HrcS HrcT HrcU HrcV HrpD HrpF HrpJ HrpY PopF1/PopF2 XopA None	Search.. Close HcrV HpaA HpaC HrcC HrcD HrcJ HrcL HrcN HrcQA+B HrcR HrcS HrcT HrcU HrpB2 HrpB7 HrpE HrpK XopA None	Search.. Close BapC BicA BipB BipC BipD BsaJ BsaK BsaL BsaM BsaO BsaP BsaQ BsaS BsaU BsaV BsaW BsaX BsaY BsaZ HrpD or BsaU InvB OrgA OrgB None	Search.. Close FlgB/FlgC/FlgF/FlgG FlgI/FlgH * FlgN FlhA FlhB FliC FliF FliG FliH FliI FliJ FliK FliN/FliM FliP FliQ FliR FliS FliT None	Search.. Close F1: α/F1: β F1: γ F1: δ/F0: b None
Gatekeeper	Gatekeeper/Affinity switch	SctW 10	SepL - B7UM95	PopN 11	YopN +TyeA	MxiC	InvE	SsaL	CopN 14, 15	BopN  19	HrpJ	HpaA 24	HpaA 24	BsaP 13	-	-
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