E.coli EPEC (O127:H6) proteome

Protein Information			Subcellular Localization
Protein ID / Accession # (UniProt))	Gene Names (UniProt)	Protein Name (UniProt)	Full name (STEPdb)	Symbol (STEPdb)	Topology Class (UniProt)	Molecular weight (kDa)	Protein Length	Protein Existence (UniProt)
			Search.. Close Cytoplasmic Cytoplasmic, Extra-cellular Cytoplasmic, Nucleoid Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm, Peripheral outer membrane protein facing the extra-cellular space Cytoplasmic, Peripheral plasma membrane protein facing the cytoplasm, Ribosomal Cytoplasmic, Periplasmic Cytoplasmic, Ribosomal Extra-cellular Inner Membrane Lipoprotein Inner Membrane Lipoprotein, Integral Inner Membrane Integral Inner Membrane Integral Inner Membrane, cytoplasmic side Outer Membrane b-barrel protein Outer Membrane Lipoprotein Outer Membrane Lipoprotein, Peripheral outer membrane protein facing the extra-cellular space Peripheral inner membrane protein facing the periplasm Peripheral outer membrane protein facing the extra-cellular space Peripheral outer membrane protein facing the periplasm Periplasmic Periplasmic, Extra-cellular Periplasmic, Peripheral outer membrane protein facing the periplasm	Search.. Close A A,F1 A,F1,F4 A,F1,r A,G A,N A,N,F1 A,r A,X B B,E E F2 F3 F4 G G,F3 G,X H I I,F4 N,B X	Search.. Close Autotransporter protein EspC translocator: Cell outer membrane Bacterial flagellum basal body but it can also form functional fimbria independent of EcpA. Cell inner membrane Cell membrane Cell outer membrane Cell surface Cytoplasm Cytoplasm. Cytoplasm. Cell inner membrane Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm. Cytoplasmic side cytosol Fimbrium Fimbrium. in a FtsZ-like pattern. it remains attached to the cell surface Lipid-anchor mainly by the tail-specific protease. Membrane Multi-pass membrane protein Multi-pass membrane protein. Multi-pass membrane protein. Note=Secreted via the type III secretion system (TTSS). Released into the host cytoplasm via TTSS and then independently inserts into the plasma membrane from a cytoplasmic location. In host cells Note=Assembles at midcell at the inner surface of the cytoplasmic membrane. Note=Associated with the membrane possibly through PlsY. Note=Attached to the inner leaflet of the outer membrane. Note=Distribution is 50-50. Note=Forms helical filaments along the long axis of the cell. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate Note=Is attached to the inner membrane when interacting with the YedZ subunit. Note=Is capable of associating with the outer membrane. Note=Localizes at mid-cell. Note=Localizes to mid-cell in an FtsZ-dependent manner. Note=Localizes to the division septum where it forms a ring structure. Note=Localizes to the division septum. Note=Localizes to the septum at mid-cell Note=Loosely associated with the cytoplasmic side of the inner membrane Note=May associate with membranes. Note=Polymerized EcpD is normally incorporated within the tip of ECP Note=Restricted to the nucleoid region. Note=The active form is cytosolic Note=The cleaved C-terminal fragment (autotransporter domain) is l Note=The SRP-RNC complex is targeted to the cytoplasmic membrane. nucleoid once secreted Peripheral membrane protein Periplasm Periplasmic side probably via SecY. Secreted Secreted autotransporter protein EspC: Secreted. Cell surface Secreted. Host cell membrane Serine protease EspC: Periplasm Single-pass membrane protein Single-pass membrane protein. Single-pass type I membrane protein Single-pass type II membrane protein Single-pass type III membrane protein while the periplasmic form is rapidly degraded None	-	-	Search.. Close Evidence at protein level Evidence at transcript level Inferred from homology Predicted
DNAA_ECO27 B7UMG9	dnaA E2348C_4013	Chromosomal replication initiator protein DnaA	Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm	A,N,F1	Cytoplasm	52	467	Inferred from homology
DPS_ECO27 B7UM08	dps E2348C_0764	DNA protection during starvation protein (EC 1.16.-.-)	Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm	A,N,F1	Cytoplasm, nucleoid	18	167	Inferred from homology
FIS_ECO27 B7UJZ2	fis E2348C_3531	DNA-binding protein Fis	Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm	A,N,F1	-	11	98	Inferred from homology
HDA_ECO27 B7UGN4	hda E2348C_2721	DnaA regulatory inactivator Hda	Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm	A,N,F1	-	26	233	Inferred from homology
HFQ_ECO27 B7UQI1	hfq E2348C_4495	RNA-binding protein Hfq	Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm	A,N,F1	-	11	102	Inferred from homology
IHFA_ECO27 B7US95	ihfA himA E2348C_1841	Integration host factor subunit alpha (IHF-alpha)	Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm	A,N,F1	-	11	99	Inferred from homology
IHFB_ECO27 B7UMZ8	ihfB himD E2348C_0905	Integration host factor subunit beta (IHF-beta)	Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm	A,N,F1	-	10	94	Inferred from homology
MALT_ECO27 B7UKC3	malT E2348C_3663	HTH-type transcriptional regulator MalT (ATP-dependent transcriptional activator MalT)	Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm	A,N,F1	-	103	901	Inferred from homology
MUKB_ECO27 B7UN10	mukB E2348C_0917	Chromosome partition protein MukB (Structural maintenance of chromosome-related protein)	Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm	A,N,F1	Cytoplasm, Note=Restricted to the nucleoid region., nucleoid	170	1486	Inferred from homology
MUKF_ECO27 B7UN08	mukF E2348C_0915	Chromosome partition protein MukF	Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm	A,N,F1	Cytoplasm, Note=Restricted to the nucleoid region., nucleoid	50	440	Inferred from homology
RECF_ECO27 B7UMG7	recF E2348C_4011	DNA replication and repair protein RecF	Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm	A,N,F1	Cytoplasm	40	357	Inferred from homology
RHLB_ECO27 B7UMN5	rhlB E2348C_4080	ATP-dependent RNA helicase RhlB (EC 3.6.4.13)	Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm	A,N,F1	Cytoplasm	47	421	Inferred from homology
RNB_ECO27 B7UR96	rnb E2348C_1480	Exoribonuclease 2 (EC 3.1.13.1) (Exoribonuclease II) (RNase II) (Ribonuclease II)	Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm	A,N,F1	Cytoplasm	72	644	Inferred from homology
RNC_ECO27 B7UH07	rnc E2348C_2844	Ribonuclease 3 (EC 3.1.26.3) (Ribonuclease III) (RNase III)	Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm	A,N,F1	Cytoplasm	25	226	Inferred from homology
RPOB_ECO27 B7UPE2	rpoB E2348C_4294	DNA-directed RNA polymerase subunit beta (RNAP subunit beta) (EC 2.7.7.6) (RNA polymerase subunit beta) (Transcriptase subunit beta)	Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm	A,N,F1	-	150	1342	Inferred from homology
RPOZ_ECO27 B7UM71	rpoZ E2348C_3913	DNA-directed RNA polymerase subunit omega (RNAP omega subunit) (EC 2.7.7.6) (RNA polymerase omega subunit) (Transcriptase subunit omega)	Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm	A,N,F1	-	10	91	Inferred from homology
RPPH_ECO27 B7UHP7	rppH nudH E2348C_3099	RNA pyrophosphohydrolase (EC 3.6.1.-) ((Di)nucleoside polyphosphate hydrolase)	Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm	A,N,F1	-	20	176	Inferred from homology
RRAA_ECO27 B7UNP9	rraA E2348C_4233	Regulator of ribonuclease activity A	Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm	A,N,F1	Cytoplasm	17	161	Inferred from homology
B7UQR2_ECO27 B7UQR2	rraB E2348C_4579	Regulator of ribonuclease activity B	Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm	A,N,F1	Cytoplasm	15	138	Inferred from homology
B7UN09_ECO27 B7UN09	mukE E2348C_0916	Chromosome partition protein MukE	Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm	A,N,F1	Cytoplasm, Note=Restricted to the nucleoid region., nucleoid	26	234	Inferred from homology
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