E.coli K-12 (MG1655) Sec Secretome

Protein Information						Subcellular Localization			Targeting/Export System
Protein ID / Accession # (UniProt)	Gene Name (UniProt)	Protein Name (UniProt)	Order Locus Name	Protein Name (STEPdb)	Reference structure	Topology Class Full name (STEPdb)	Symbol (STEPdb)	Topology Class UniProt	Extracellular Appendage	First Level Targeting Chaperoning	First Level Secretion System	Second Level Targeting Chaperoning	Second Level Secretion System	K-12 Core Proteome (yes/no)	K-12 Basic Proteome (yes/no)
						Search.. Close Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm, Peripheral outer membrane protein facing the extra-cellular space Cytoplasmic, Periplasmic Extra-cellular Inner Membrane Lipoprotein Outer Membrane b-barrel protein Outer Membrane Lipoprotein Outer Membrane Lipoprotein, Peripheral outer membrane protein facing the extra-cellular space Peripheral inner membrane protein facing the periplasm Peripheral inner membrane protein facing the periplasm, periplasmic Peripheral outer membrane protein facing the extra-cellular space Peripheral outer membrane protein facing the periplasm Periplasmic Periplasmic, Extra-cellular Periplasmic, Peripheral outer membrane protein facing the periplasm	Search.. Close A,F1,F4 A,G E F2 F2,G F3 F4 G G,F3 G,X H I I,F4 X	Search.. Close Antigen 43: Periplasm Cell inner membrane Cell membrane Cell outer membrane Cytoplasm Cytoplasmic side cytoskeleton Secreted Cell surface cytosol Fimbrium Lipid-anchor Membrane Multi-pass membrane protein Peripheral membrane protein Periplasm Periplasm Bacterial flagellum basal body Periplasm Cytoplasm Periplasmic side Periplasmic side Periplasm Probable autotransporter YfaL translocator: Cell outer membrane Probable autotransporter YfaL: Periplasm Probable secreted autotransporter protein YfaL: Secreted Cell surface Secreted Secreted Periplasm Host cell membrane Single-pass membrane protein None	Search.. Close Curli fimbriae flagellum None	Search.. Close DmsD SECB SRP SRP (exp) TF None	Search.. Close SEC TAT,SEC	Search.. Close DEGP DSBA DSBC SKP SURA YfgM None	Search.. Close Autotransporter(T5S) BAM CU Curli Fla LOL OMV T2S TAM None	Search.. Close no yes	Search.. Close no yes
YMGJ_ECOLI A5A612	ymgJ	Uncharacterized protein YmgJ	b4594	periplasmic protein (SEC through IM), YmgJ	ab initio Zhang model E10797 (score: 0.515)	Periplasmic	G	-	-	-	SEC	-	-	no	yes
YJBT_ECOLI A5A628	yjbT	Uncharacterized protein YjbT	b4620	periplasmic protein (SEC through IM), YjbT	ab initio Zhang model E10740 (score: 0.458)	Periplasmic	G	-	-	-	SEC	-	-	no	yes
RZOQ_ECOLI C1P601	rzoQ	Putative lipoprotein RzoQ	b4689 JW1545.1	IM lipoprotein (SEC through IM), inserted in OM by LOL), Putative RzoQ	ab initio Zhang model E10367 (score: 0.604)	Inner Membrane Lipoprotein	E	Cell membrane	-	-	SEC	-	LOL	no	yes
YPDI_ECOLI O32528	ypdI	Uncharacterized lipoprotein YpdI	b2376 JW2373	OM lipoprotein (SEC through IM, inserted in OM by LOL), YpdI	SWISS-MODEL named O32528 (score: 0.5148481172)	Outer Membrane Lipoprotein	I	Cell membrane	-	-	SEC	-	LOL	no	yes
YFJS_ECOLI O52982	yfjS	Lipoprotein YfjS	b2636 JW5921	IM lipoprotein (SEC through IM, inserted in OM by LOL), YfjS	SWISS-MODEL named O52982 (score: 0.6690054512)	Inner Membrane Lipoprotein	E	Cell inner membrane	-	-	SEC	-	LOL	no	no
PPB_ECOLI P00634	phoA	Alkaline phosphatase (APase) (EC 3.1.3.1)	b0383 JW0374	periplasmic protein (SEC through IM), Alkaline phosphatase PhoA	1y6v PDB ID, chain A, for protein P00634	Periplasmic	G	Periplasm	-	-	SEC	DSBA	-	no	yes
ASPG2_ECOLI P00805	ansB	L-asparaginase 2 (EC 3.5.1.1) (L-asparaginase II) (L-ASNase II) (L-asparagine amidohydrolase II) (Colaspase)	b2957 JW2924	periplasmic protein (SEC through IM), L-asparaginase 2 AnsB	5mq5 PDB ID, chain B, for protein P00805	Periplasmic	G	Periplasm	-	-	SEC	-	-	yes	yes
AMPC_ECOLI P00811	ampC	Beta-lactamase (EC 3.5.2.6) (Cephalosporinase)	b4150 JW4111	periplasmic protein (SEC through IM), Beta-lactamase AmpC	2ffy PDB ID, chain A, for protein P00811	Periplasmic	G	Periplasm	-	-	SEC	-	-	yes	yes
ARAF_ECOLI P02924	araF	L-arabinose-binding periplasmic protein (ABP)	b1901 JW1889	periplasmic protein (SEC through IM), L-arabinose-binding periplasmic AraF	8abp PDB ID, chain A, for protein P02924	Periplasmic	G	Periplasm	-	-	SEC	-	-	yes	yes
RBSB_ECOLI P02925	rbsB	Ribose import binding protein RbsB	b3751 JW3730	periplasmic protein (SEC through IM), Ribose import binding RbsB	2dri PDB ID, chain A, for protein P02925	Periplasmic	G	Periplasm	-	-	SEC	SKP	-	no	yes
TOLC_ECOLI P02930	tolC	Outer membrane protein TolC (Multidrug efflux pump subunit TolC) (Outer membrane factor TolC)	b3035 JW5503	OM b-barrel protein (SEC through IM, inserted in OM by BAM), TolC	1tqq PDB ID, chain A, for protein P02930	Outer Membrane b-barrel protein	H	Cell outer membrane	-	SECB	SEC	SKP	BAM	yes	yes
OMPF_ECOLI P02931	ompF	Outer membrane protein F (Outer membrane protein 1A) (Outer membrane protein B) (Outer membrane protein IA) (Porin OmpF)	b0929 JW0912	OM b-barrel protein (SEC through IM, inserted in OM by BAM), OmpF	3poq PDB ID, chain A, for protein P02931	Outer Membrane b-barrel protein	H	Cell outer membrane	-	TF	SEC	SKP, SURA	BAM	yes	yes
PHOE_ECOLI P02932	phoE	Outer membrane pore protein E	b0241 JW0231	OM b-barrel protein (SEC through IM, inserted in OM by BAM), PhoE	1pho PDB ID, chain A, for protein P02932	Outer Membrane b-barrel protein	H	Cell outer membrane, Multi-pass membrane protein	-	-	SEC	-	BAM	yes	yes
LAMB_ECOLI P02943	lamB	Maltoporin (Lambda receptor protein) (Maltose-inducible porin)	b4036 JW3996	OM b-barrel protein (SEC through IM, inserted in OM by BAM), Maltoporin LamB	1af6 PDB ID, chain A, for protein P02943	Outer Membrane b-barrel protein	H	Cell outer membrane	-	-	SEC	DEGP, SKP, SURA	BAM	yes	yes
MALM_ECOLI P03841	malM	Maltose operon periplasmic protein	b4037 JW3997	periplasmic protein (SEC through IM), Maltose operon periplasmic protein MalM	ab initio Zhang model E12092 (score: 0.39)	Periplasmic	G	Periplasm	-	-	SEC	-	-	yes	yes
FIMA1_ECOLI P04128	fimA	Type-1 fimbrial protein, A chain (Type-1A pilin)	b4314 JW4277	Fimbrial extra-cellular peripheral OM protein (SEC through IM, chaperone usher export system over OM), Type-1 protein, A chain FimA	2m5g PDB ID, chain A, for protein P04128	Peripheral outer membrane protein facing the extra-cellular space	F4	Fimbrium	fimbriae	-	SEC	-	CU	yes	yes
LIVK_ECOLI P04816	livK	Leucine-specific-binding protein (L-BP) (LS-BP)	b3458 JW3423	periplasmic protein (SEC through IM), Leucine-specific-binding LivK	2lbp PDB ID, chain A, for protein P04816	Periplasmic	G	Periplasm	-	-	SEC	DSBA	-	yes	yes
NLPA_ECOLI P04846	nlpA	Lipoprotein 28	b3661 JW3635	IM lipoprotein (SEC through IM, inserted in OM by LOL), NlpA	TBM Zhang model E12340 (score: 0.873)	Inner Membrane Lipoprotein	E	Cell inner membrane, Lipid-anchor	-	-	SEC	-	LOL	yes	yes
PTRA_ECOLI P05458	ptrA	Protease 3 (EC 3.4.24.55) (Pitrilysin) (Protease III) (Protease pi)	b2821 JW2789	periplasmic protein (SEC through IM), Protease 3 PtrA	1q2l PDB ID, chain A, for protein P05458	Periplasmic	G	Periplasm	-	-	SEC	SURA	-	yes	yes
FEPA_ECOLI P05825	fepA	Ferrienterobactin receptor (Enterobactin outer-membrane receptor)	b0584 JW5086	OM b-barrel protein (SEC through IM, inserted in OM by BAM), Ferrienterobactin receptor FepA	1fep PDB ID, chain A, for protein P05825	Outer Membrane b-barrel protein	H	Cell outer membrane, Multi-pass membrane protein	-	-	SEC	SKP	BAM	yes	yes
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