Peripheral Inner Membrane Proteome of E.coli K-12 (MG1655)
| Protein Information | Subcellular Localization | Targeting/Export System | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Protein ID / Accession # (UniProt) |
Gene Name (UniProt) |
Protein Name (UniProt) |
Order Locus Name |
Protein Name (STEPdb) |
Reference structure |
Topology Class Full name (STEPdb) |
Symbol (STEPdb) |
Topology Class UniProt |
Extracellular Appendage | First Level Targeting Chaperoning |
First Level Secretion System |
Second Level Targeting Chaperoning |
Second Level Secretion System |
K-12 Core Proteome (yes/no) |
K-12 Basic Proteome (yes/no) |
| SGRT_ECOLI C1P5Z7 |
sgrT | Putative inhibitor of glucose uptake transporter SgrT | b4662 JW0068.1 | cytoplasmic peripheral IM protein, Putative inhibitor of glucose uptake transporter SgrT | no structure available | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A,F1 | - | - | - | - | - | - | no | yes |
| YOBI_ECOLI C1P604 |
yobI | Uncharacterized protein YobI | b4677 JW1850.1 | cytoplasmic peripheral IM protein, YobI | no structure available | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A,F1 | - | - | - | - | - | - | no | yes |
| AZUC_ECOLI C1P605 |
azuC | Uncharacterized protein AzuC | b4663 JW1891.1 | cytoplasmic peripheral IM protein, AzuC | no structure available | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A,F1 | Cell inner membrane | - | - | - | - | - | no | yes |
| YSHB_ECOLI C1P620 |
yshB | Uncharacterized protein YshB | b4686 JW3839.1 | cytoplasmic peripheral IM protein, YshB | no structure available | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A,F1 | - | - | - | - | - | - | no | yes |
| 6PGD_ECOLI P00350 |
gnd | 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) | b2029 JW2011 | cytoplasmic peripheral IM protein, 6-phosphogluconate dehydrogenase, decarboxylating Gnd | 3fwn PDB ID, chain A, for protein P00350 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A,F1 | - | - | - | - | - | - | yes | yes |
| FRDA_ECOLI P00363 |
frdA | Fumarate reductase flavoprotein subunit (EC 1.3.5.4) | b4154 JW4115 | cytoplasmic peripheral IM protein, Fumarate reductase flavosubunit FrdA | 5vpn PDB ID, chain E, for protein P00363 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A,F1 | - | - | - | - | - | - | yes | yes |
| DHNA_ECOLI P00393 |
ndh | NADH dehydrogenase (EC 1.6.99.3) | b1109 JW1095 | cytoplasmic peripheral IM protein, NADH dehydrogenase Ndh | TBM Zhang model E12316 (score: 0.791) | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A,F1 | Cell membrane | - | - | - | - | - | yes | yes |
| RIR1_ECOLI P00452 |
nrdA | Ribonucleoside-diphosphate reductase 1 subunit alpha (EC 1.17.4.1) (Protein B1) (Ribonucleoside-diphosphate reductase 1 R1 subunit) (Ribonucleotide reductase 1) | b2234 JW2228 | cytoplasmic peripheral IM protein, Ribonucleoside-diphosphate reductase 1 subunit alpha NrdA | 5r1r PDB ID, chain A, for protein P00452 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A,F1 | - | - | TF | - | - | - | yes | yes |
| AAT_ECOLI P00509 |
aspC | Aspartate aminotransferase (AspAT) (EC 2.6.1.1) (Transaminase A) | b0928 JW0911 | cytoplasmic peripheral IM protein, Aspartate aminotransferase AspC | 4dbc PDB ID, chain A, for protein P00509 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A,F1 | Cytoplasm | - | - | - | - | - | yes | yes |
| AK1H_ECOLI P00561 |
thrA | Bifunctional aspartokinase/homoserine dehydrogenase 1 (Aspartokinase I/homoserine dehydrogenase I) (AKI-HDI) [Includes: Aspartokinase (EC 2.7.2.4); Homoserine dehydrogenase (EC 1.1.1.3)] | b0002 JW0001 | cytoplasmic peripheral IM protein, Bifunctional aspartokinase/homoserine dehydrogenase 1 ThrA | TBM Zhang model E13013 (score: 0.716) | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A,F1 | - | - | TF | - | - | - | yes | yes |
| AK2H_ECOLI P00562 |
metL | Bifunctional aspartokinase/homoserine dehydrogenase 2 (Aspartokinase II/homoserine dehydrogenase II) (AKII-HDII) [Includes: Aspartokinase (EC 2.7.2.4); Homoserine dehydrogenase (EC 1.1.1.3)] | b3940 JW3911 | cytoplasmic peripheral IM protein, Bifunctional aspartokinase/homoserine dehydrogenase 2 MetL | TBM Zhang model E12163 (score: 0.725) | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A,F1 | - | - | - | - | - | - | yes | yes |
| RPOD_ECOLI P00579 |
rpoD | RNA polymerase sigma factor RpoD (Sigma-70) | b3067 JW3039 | cytoplasmic nucleoid peripheral IM protein, RNA polymerase sigma factor RpoD | 4lk1 PDB ID, chain F, for protein P00579 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A,N,F1 | Cytoplasm | - | TF | - | - | - | yes | yes |
| DPO1_ECOLI P00582 |
polA | DNA polymerase I (POL I) (EC 2.7.7.7) | b3863 JW3835 | cytoplasmic nucleoid peripheral IM protein, DNA polymerase I PolA | 1d8y PDB ID, chain A, for protein P00582 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A,N,F1 | - | - | - | - | - | - | no | yes |
| CAPP_ECOLI P00864 |
ppc | Phosphoenolpyruvate carboxylase (PEPC) (PEPCase) (EC 4.1.1.31) | b3956 JW3928 | cytoplasmic peripheral IM protein, Phosphoenolpyruvate carboxylase Ppc | 1jqn PDB ID, chain A, for protein P00864 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A,F1 | - | - | - | - | - | - | yes | yes |
| TRPE_ECOLI P00895 |
trpE | Anthranilate synthase component 1 (AS) (ASI) (EC 4.1.3.27) | b1264 JW1256 | cytoplasmic peripheral IM protein, Anthranilate synthase component 1 TrpE | TBM Zhang model E13064 (score: 0.997) | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A,F1 | - | - | - | - | - | - | yes | yes |
| TRPGD_ECOLI P00904 |
trpGD | Bifunctional protein TrpGD [Includes: Anthranilate synthase component 2 (AS) (ASII) (EC 4.1.3.27) (Anthranilate synthase, glutamine amidotransferase component); Anthranilate phosphoribosyltransferase (EC 2.4.2.18)] | b1263 JW1255 | cytoplasmic peripheral IM protein, Bifunctional TrpG | TBM Zhang model E13063 (score: 0.81) | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A,F1 | - | - | - | - | - | - | yes | yes |
| SYA_ECOLI P00957 |
alaS | Alanine--tRNA ligase (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS) | b2697 JW2667 | cytoplasmic nucleoid peripheral IM protein, Alanine--tRNA ligase AlaS | 3hy0 PDB ID, chain A, for protein P00957 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A,N,F1 | Cytoplasm | - | TF | - | - | - | no | yes |
| SYM_ECOLI P00959 |
metG | Methionine--tRNA ligase (EC 6.1.1.10) (Methionyl-tRNA synthetase) (MetRS) | b2114 JW2101 | cytoplasmic peripheral IM protein, Methionine--tRNA ligase MetG | 1pfv PDB ID, chain A, for protein P00959 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A,F1 | Cytoplasm | - | TF | - | - | - | yes | yes |
| SYGA_ECOLI P00960 |
glyQ | Glycine--tRNA ligase alpha subunit (EC 6.1.1.14) (Glycyl-tRNA synthetase alpha subunit) (GlyRS) | b3560 JW3531 | cytoplasmic peripheral IM protein, Glycine--tRNA ligase alpha subunit GlyQ | TBM Zhang model E11709 (score: 0.946) | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A,F1 | Cytoplasm | - | TF | - | - | - | no | yes |
| SYGB_ECOLI P00961 |
glyS | Glycine--tRNA ligase beta subunit (EC 6.1.1.14) (Glycyl-tRNA synthetase beta subunit) (GlyRS) | b3559 JW3530 | cytoplasmic peripheral IM protein, Glycine--tRNA ligase beta subunit GlyS | TBM Zhang model E11710 (score: 0.47) | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A,F1 | Cytoplasm | - | - | - | - | - | yes | yes |
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