Peripheral Inner Membrane Proteome of E.coli K-12 (MG1655)

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Nucleoid Cytoplasmic Peripheral inner membrane protein facing the cytoplasm Integral inner membrane Ribosomal Inner membrane lipoprotein Peripheral inner membrane protein facing the periplasm Periplasmic Peripheral outer membrane protein facing the periplasm Outer membrane β-barrel protein Peripheral outer membrane protein facing the extra-cellular space Extra-cellular Outer membrane lipoprotein

Protein Information Subcellular Localization Targeting/Export System
Protein ID /
Accession #
(UniProt)
Gene Name
(UniProt)
Protein Name
(UniProt)
Order
Locus Name
Protein Name
(STEPdb)
Reference structure
Topology Class
Full name
(STEPdb)
Symbol
(STEPdb)
Topology Class
UniProt
Extracellular Appendage First Level
Targeting
Chaperoning
First Level
Secretion
System
Second Level
Targeting
Chaperoning
Second Level
Secretion
System
K-12 Core
Proteome
(yes/no)
K-12 Basic
Proteome
(yes/no)
SGRT_ECOLI
C1P5Z7
sgrT Putative inhibitor of glucose uptake transporter SgrT b4662 JW0068.1 cytoplasmic peripheral IM protein, Putative inhibitor of glucose uptake transporter SgrT no structure available Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm A,F1 - - - - - - no yes
YOBI_ECOLI
C1P604
yobI Uncharacterized protein YobI b4677 JW1850.1 cytoplasmic peripheral IM protein, YobI no structure available Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm A,F1 - - - - - - no yes
AZUC_ECOLI
C1P605
azuC Uncharacterized protein AzuC b4663 JW1891.1 cytoplasmic peripheral IM protein, AzuC no structure available Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm A,F1 Cell inner membrane - - - - - no yes
YSHB_ECOLI
C1P620
yshB Uncharacterized protein YshB b4686 JW3839.1 cytoplasmic peripheral IM protein, YshB no structure available Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm A,F1 - - - - - - no yes
6PGD_ECOLI
P00350
gnd 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) b2029 JW2011 cytoplasmic peripheral IM protein, 6-phosphogluconate dehydrogenase, decarboxylating Gnd 3fwn PDB ID, chain A, for protein P00350 Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm A,F1 - - - - - - yes yes
FRDA_ECOLI
P00363
frdA Fumarate reductase flavoprotein subunit (EC 1.3.5.4) b4154 JW4115 cytoplasmic peripheral IM protein, Fumarate reductase flavosubunit FrdA 5vpn PDB ID, chain E, for protein P00363 Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm A,F1 - - - - - - yes yes
DHNA_ECOLI
P00393
ndh NADH dehydrogenase (EC 1.6.99.3) b1109 JW1095 cytoplasmic peripheral IM protein, NADH dehydrogenase Ndh TBM Zhang model E12316 (score: 0.791) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm A,F1 Cell membrane - - - - - yes yes
RIR1_ECOLI
P00452
nrdA Ribonucleoside-diphosphate reductase 1 subunit alpha (EC 1.17.4.1) (Protein B1) (Ribonucleoside-diphosphate reductase 1 R1 subunit) (Ribonucleotide reductase 1) b2234 JW2228 cytoplasmic peripheral IM protein, Ribonucleoside-diphosphate reductase 1 subunit alpha NrdA 5r1r PDB ID, chain A, for protein P00452 Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm A,F1 - - TF - - - yes yes
AAT_ECOLI
P00509
aspC Aspartate aminotransferase (AspAT) (EC 2.6.1.1) (Transaminase A) b0928 JW0911 cytoplasmic peripheral IM protein, Aspartate aminotransferase AspC 4dbc PDB ID, chain A, for protein P00509 Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm A,F1 Cytoplasm - - - - - yes yes
AK1H_ECOLI
P00561
thrA Bifunctional aspartokinase/homoserine dehydrogenase 1 (Aspartokinase I/homoserine dehydrogenase I) (AKI-HDI) [Includes: Aspartokinase (EC 2.7.2.4); Homoserine dehydrogenase (EC 1.1.1.3)] b0002 JW0001 cytoplasmic peripheral IM protein, Bifunctional aspartokinase/homoserine dehydrogenase 1 ThrA TBM Zhang model E13013 (score: 0.716) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm A,F1 - - TF - - - yes yes
AK2H_ECOLI
P00562
metL Bifunctional aspartokinase/homoserine dehydrogenase 2 (Aspartokinase II/homoserine dehydrogenase II) (AKII-HDII) [Includes: Aspartokinase (EC 2.7.2.4); Homoserine dehydrogenase (EC 1.1.1.3)] b3940 JW3911 cytoplasmic peripheral IM protein, Bifunctional aspartokinase/homoserine dehydrogenase 2 MetL TBM Zhang model E12163 (score: 0.725) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm A,F1 - - - - - - yes yes
RPOD_ECOLI
P00579
rpoD RNA polymerase sigma factor RpoD (Sigma-70) b3067 JW3039 cytoplasmic nucleoid peripheral IM protein, RNA polymerase sigma factor RpoD 4lk1 PDB ID, chain F, for protein P00579 Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm A,N,F1 Cytoplasm - TF - - - yes yes
DPO1_ECOLI
P00582
polA DNA polymerase I (POL I) (EC 2.7.7.7) b3863 JW3835 cytoplasmic nucleoid peripheral IM protein, DNA polymerase I PolA 1d8y PDB ID, chain A, for protein P00582 Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm A,N,F1 - - - - - - no yes
CAPP_ECOLI
P00864
ppc Phosphoenolpyruvate carboxylase (PEPC) (PEPCase) (EC 4.1.1.31) b3956 JW3928 cytoplasmic peripheral IM protein, Phosphoenolpyruvate carboxylase Ppc 1jqn PDB ID, chain A, for protein P00864 Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm A,F1 - - - - - - yes yes
TRPE_ECOLI
P00895
trpE Anthranilate synthase component 1 (AS) (ASI) (EC 4.1.3.27) b1264 JW1256 cytoplasmic peripheral IM protein, Anthranilate synthase component 1 TrpE TBM Zhang model E13064 (score: 0.997) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm A,F1 - - - - - - yes yes
TRPGD_ECOLI
P00904
trpGD Bifunctional protein TrpGD [Includes: Anthranilate synthase component 2 (AS) (ASII) (EC 4.1.3.27) (Anthranilate synthase, glutamine amidotransferase component); Anthranilate phosphoribosyltransferase (EC 2.4.2.18)] b1263 JW1255 cytoplasmic peripheral IM protein, Bifunctional TrpG TBM Zhang model E13063 (score: 0.81) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm A,F1 - - - - - - yes yes
SYA_ECOLI
P00957
alaS Alanine--tRNA ligase (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS) b2697 JW2667 cytoplasmic nucleoid peripheral IM protein, Alanine--tRNA ligase AlaS 3hy0 PDB ID, chain A, for protein P00957 Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm A,N,F1 Cytoplasm - TF - - - no yes
SYM_ECOLI
P00959
metG Methionine--tRNA ligase (EC 6.1.1.10) (Methionyl-tRNA synthetase) (MetRS) b2114 JW2101 cytoplasmic peripheral IM protein, Methionine--tRNA ligase MetG 1pfv PDB ID, chain A, for protein P00959 Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm A,F1 Cytoplasm - TF - - - yes yes
SYGA_ECOLI
P00960
glyQ Glycine--tRNA ligase alpha subunit (EC 6.1.1.14) (Glycyl-tRNA synthetase alpha subunit) (GlyRS) b3560 JW3531 cytoplasmic peripheral IM protein, Glycine--tRNA ligase alpha subunit GlyQ TBM Zhang model E11709 (score: 0.946) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm A,F1 Cytoplasm - TF - - - no yes
SYGB_ECOLI
P00961
glyS Glycine--tRNA ligase beta subunit (EC 6.1.1.14) (Glycyl-tRNA synthetase beta subunit) (GlyRS) b3559 JW3530 cytoplasmic peripheral IM protein, Glycine--tRNA ligase beta subunit GlyS TBM Zhang model E11710 (score: 0.47) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm A,F1 Cytoplasm - - - - - yes yes
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