E. coli K-12 / MG1655/ ATCC 47076 proteome

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Nucleoid Cytoplasmic Peripheral inner membrane protein facing the cytoplasm Integral inner membrane Ribosomal Inner membrane lipoprotein Peripheral inner membrane protein facing the periplasm Periplasmic Peripheral outer membrane protein facing the periplasm Outer membrane β-barrel protein Peripheral outer membrane protein facing the extra-cellular space Extra-cellular Outer membrane lipoprotein

Protein Information Subcellular Localization Targeting/Export System
Protein ID /
Accession #
(UniProt)
Gene Name
(UniProt)
Protein Name
(UniProt)
Order
Locus Name
Protein Name
(STEPdb)
Reference structure
Topology Class
Full name
(STEPdb)
Symbol
(STEPdb)
Topology Class
UniProt
Extracellular Appendage First Level
Targeting
Chaperoning
First Level
Secretion
System
Second Level
Targeting
Chaperoning
Second Level
Secretion
System
K-12 Core
Proteome
(yes/no)
K-12 Basic
Proteome
(yes/no)
SODM_ECOLI
P00448
sodA Superoxide dismutase [Mn] (EC 1.15.1.1) (MnSOD) b3908 JW3879 periplasmic protein (SEC through IM), Superoxide dismutase SodA 1ix9 PDB ID, chain A, for protein P00448 Periplasmic G - - - SEC, non classical - - yes yes
AAT_ECOLI
P00509
aspC Aspartate aminotransferase (AspAT) (EC 2.6.1.1) (Transaminase A) b0928 JW0911 cytoplasmic peripheral IM protein, Aspartate aminotransferase AspC 4dbc PDB ID, chain A, for protein P00509 Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm A,F1 Cytoplasm - - - - - yes yes
TOLC_ECOLI
P02930
tolC Outer membrane protein TolC (Multidrug efflux pump subunit TolC) (Outer membrane factor TolC) b3035 JW5503 OM b-barrel protein (SEC through IM, inserted in OM by BAM), TolC 1tqq PDB ID, chain A, for protein P02930 Outer Membrane b-barrel protein H Cell outer membrane - SECB SEC SKP BAM yes yes
MIOC_ECOLI
P03817
mioC Protein MioC b3742 JW3720 cytoplasmic protein, MioC 2hna PDB ID, chain A, for protein P03817 Cytoplasmic A - - - - - - yes yes
FRSA_ECOLI
P04335
frsA Esterase FrsA (EC 3.1.-.-) b0239 JW0229 cytoplasmic protein, Esterase FrsA TBM Zhang model E11567 (score: 0.615) Cytoplasmic A - - - - - - yes yes
GSHB_ECOLI
P04425
gshB Glutathione synthetase (EC 6.3.2.3) (GSH synthetase) (GSH-S) (GSHase) (Glutathione synthase) b2947 JW2914 cytoplasmic protein, Glutathione synthetase GshB 1gsa PDB ID, chain A, for protein P04425 Cytoplasmic A - - - - - - yes yes
TYRB_ECOLI
P04693
tyrB Aromatic-amino-acid aminotransferase (ARAT) (AROAT) (EC 2.6.1.57) (Beta-methylphenylalanine transaminase) (EC 2.6.1.107) b4054 JW4014 cytoplasmic protein, Aromatic-amino-acid aminotransferase TyrB 3fsl PDB ID, chain A, for protein P04693 Cytoplasmic A Cytoplasm - - - - - yes yes
PDXB_ECOLI
P05459
pdxB Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) b2320 JW2317 cytoplasmic protein, Erythronate-4-phosphate dehydrogenase PdxB TBM Zhang model E12445 (score: 0.684) Cytoplasmic A Cytoplasm - - - - - yes yes
DLD_ECOLI
P06149
dld Quinone-dependent D-lactate dehydrogenase (EC 1.1.5.12) ((R)-lactate:quinone 2-oxidoreductase) (D-lactate dehydrogenase) (D-LDH) (Respiratory D-lactate dehydrogenase) b2133 JW2121 cytoplasmic peripheral IM protein, Quinone-dependent D-lactate dehydrogenase Dld 1f0x PDB ID, chain A, for protein P06149 Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm A,F1 Cell inner membrane - - - - - yes yes
BTUE_ECOLI
P06610
btuE Thioredoxin/glutathione peroxidase BtuE (EC 1.11.1.15) (EC 1.11.1.9) b1710 JW1700 cytoplasmic protein, Thioredoxin/glutathione peroxidase BtuE TBM Zhang model E11111 (score: 0.821) Cytoplasmic A Periplasm - - SEC, non classical - - yes yes
GSHR_ECOLI
P06715
gor Glutathione reductase (GR) (GRase) (EC 1.8.1.7) b3500 JW3467 cytoplasmic protein, Glutathione reductase Gor 1ges PDB ID, chain B, for protein P06715 Cytoplasmic A Cytoplasm - - - - - yes yes
FHUA_ECOLI
P06971
fhuA Ferrichrome outer membrane transporter/phage receptor (Ferric hydroxamate receptor) (Ferric hydroxamate uptake) (Ferrichrome-iron receptor) b0150 JW0146 OM b-barrel protein (SEC through IM, inserted in OM by BAM), Ferrichrome transporter/phage receptor FhuA 1by5 PDB ID, chain A, for protein P06971 Outer Membrane b-barrel protein H Cell outer membrane - SECB SEC SKP, SURA BAM yes yes
PROA_ECOLI
P07004
proA Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase) (GSA dehydrogenase) b0243 JW0233 cytoplasmic peripheral IM protein, Gamma-glutamyl phosphate reductase ProA TBM Zhang model E12566 (score: 0.99) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm A,F1 Cytoplasm - - - - - yes yes
USHA_ECOLI
P07024
ushA Protein UshA [Includes: UDP-sugar hydrolase (EC 3.6.1.45) (UDP-sugar diphosphatase) (UDP-sugar pyrophosphatase); 5'-nucleotidase (5'-NT) (EC 3.1.3.5)] b0480 JW0469 periplasmic protein (SEC through IM), UshA 1hpu PDB ID, chain A, for protein P07024 Periplasmic G Periplasm - - SEC - - no yes
AROB_ECOLI
P07639
aroB 3-dehydroquinate synthase (DHQS) (EC 4.2.3.4) b3389 JW3352 cytoplasmic protein, 3-dehydroquinate synthase AroB TBM Zhang model E11019 (score: 0.881) Cytoplasmic A Cytoplasm - - - - - yes yes
GLGB_ECOLI
P07762
glgB 1,4-alpha-glucan branching enzyme GlgB (EC 2.4.1.18) (1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase) (Alpha-(1->4)-glucan branching enzyme) (Glycogen branching enzyme) (BE) b3432 JW3395 cytoplasmic protein, 1,4-alpha-glucan branching enzyme GlgB 4lpc PDB ID, chain B, for protein P07762 Cytoplasmic A - - - - - - yes yes
IDH_ECOLI
P08200
icd Isocitrate dehydrogenase [NADP] (IDH) (EC 1.1.1.42) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase) b1136 JW1122 cytoplasmic peripheral IM protein, Isocitrate dehydrogenase (NADP) Icd 1pb1 PDB ID, chain A, for protein P08200 Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm A,F1 - - TF - - - yes yes
HEM4_ECOLI
P09126
hemD Uroporphyrinogen-III synthase (UROS) (EC 4.2.1.75) (Hydroxymethylbilane hydrolyase [cyclizing]) (Uroporphyrinogen-III cosynthase) b3804 JW3776 cytoplasmic protein, Uroporphyrinogen-III synthase HemD TBM Zhang model E11779 (score: 0.683) Cytoplasmic A - - - - - - yes yes
PFLB_ECOLI
P09373
pflB Formate acetyltransferase 1 (EC 2.3.1.54) (Pyruvate formate-lyase 1) b0903 JW0886 cytoplasmic peripheral IM protein, Formate acetyltransferase 1 PflB 1h16 PDB ID, chain A, for protein P09373 Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm A,F1 Cytoplasm - TF - - - yes yes
YIDB_ECOLI
P09996
yidB Uncharacterized protein YidB b3698 JW3675 cytoplasmic protein, YidB TBM Zhang model E10715 (score: 0.966) Cytoplasmic A - - - - - - yes yes
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