E. coli K-12 / MG1655/ ATCC 47076 proteome
| Protein Information | Subcellular Localization | Targeting/Export System | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Protein ID / Accession # (UniProt) |
Gene Name (UniProt) |
Protein Name (UniProt) |
Order Locus Name |
Protein Name (STEPdb) |
Reference structure |
Topology Class Full name (STEPdb) |
Symbol (STEPdb) |
Topology Class UniProt |
Extracellular Appendage | First Level Targeting Chaperoning |
First Level Secretion System |
Second Level Targeting Chaperoning |
Second Level Secretion System |
K-12 Core Proteome (yes/no) |
K-12 Basic Proteome (yes/no) |
| SODM_ECOLI P00448 |
sodA | Superoxide dismutase [Mn] (EC 1.15.1.1) (MnSOD) | b3908 JW3879 | periplasmic protein (SEC through IM), Superoxide dismutase SodA | 1ix9 PDB ID, chain A, for protein P00448 | Periplasmic | G | - | - | - | SEC, non classical | - | - | yes | yes |
| AAT_ECOLI P00509 |
aspC | Aspartate aminotransferase (AspAT) (EC 2.6.1.1) (Transaminase A) | b0928 JW0911 | cytoplasmic peripheral IM protein, Aspartate aminotransferase AspC | 4dbc PDB ID, chain A, for protein P00509 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A,F1 | Cytoplasm | - | - | - | - | - | yes | yes |
| TOLC_ECOLI P02930 |
tolC | Outer membrane protein TolC (Multidrug efflux pump subunit TolC) (Outer membrane factor TolC) | b3035 JW5503 | OM b-barrel protein (SEC through IM, inserted in OM by BAM), TolC | 1tqq PDB ID, chain A, for protein P02930 | Outer Membrane b-barrel protein | H | Cell outer membrane | - | SECB | SEC | SKP | BAM | yes | yes |
| MIOC_ECOLI P03817 |
mioC | Protein MioC | b3742 JW3720 | cytoplasmic protein, MioC | 2hna PDB ID, chain A, for protein P03817 | Cytoplasmic | A | - | - | - | - | - | - | yes | yes |
| FRSA_ECOLI P04335 |
frsA | Esterase FrsA (EC 3.1.-.-) | b0239 JW0229 | cytoplasmic protein, Esterase FrsA | TBM Zhang model E11567 (score: 0.615) | Cytoplasmic | A | - | - | - | - | - | - | yes | yes |
| GSHB_ECOLI P04425 |
gshB | Glutathione synthetase (EC 6.3.2.3) (GSH synthetase) (GSH-S) (GSHase) (Glutathione synthase) | b2947 JW2914 | cytoplasmic protein, Glutathione synthetase GshB | 1gsa PDB ID, chain A, for protein P04425 | Cytoplasmic | A | - | - | - | - | - | - | yes | yes |
| TYRB_ECOLI P04693 |
tyrB | Aromatic-amino-acid aminotransferase (ARAT) (AROAT) (EC 2.6.1.57) (Beta-methylphenylalanine transaminase) (EC 2.6.1.107) | b4054 JW4014 | cytoplasmic protein, Aromatic-amino-acid aminotransferase TyrB | 3fsl PDB ID, chain A, for protein P04693 | Cytoplasmic | A | Cytoplasm | - | - | - | - | - | yes | yes |
| PDXB_ECOLI P05459 |
pdxB | Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) | b2320 JW2317 | cytoplasmic protein, Erythronate-4-phosphate dehydrogenase PdxB | TBM Zhang model E12445 (score: 0.684) | Cytoplasmic | A | Cytoplasm | - | - | - | - | - | yes | yes |
| DLD_ECOLI P06149 |
dld | Quinone-dependent D-lactate dehydrogenase (EC 1.1.5.12) ((R)-lactate:quinone 2-oxidoreductase) (D-lactate dehydrogenase) (D-LDH) (Respiratory D-lactate dehydrogenase) | b2133 JW2121 | cytoplasmic peripheral IM protein, Quinone-dependent D-lactate dehydrogenase Dld | 1f0x PDB ID, chain A, for protein P06149 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A,F1 | Cell inner membrane | - | - | - | - | - | yes | yes |
| BTUE_ECOLI P06610 |
btuE | Thioredoxin/glutathione peroxidase BtuE (EC 1.11.1.15) (EC 1.11.1.9) | b1710 JW1700 | cytoplasmic protein, Thioredoxin/glutathione peroxidase BtuE | TBM Zhang model E11111 (score: 0.821) | Cytoplasmic | A | Periplasm | - | - | SEC, non classical | - | - | yes | yes |
| GSHR_ECOLI P06715 |
gor | Glutathione reductase (GR) (GRase) (EC 1.8.1.7) | b3500 JW3467 | cytoplasmic protein, Glutathione reductase Gor | 1ges PDB ID, chain B, for protein P06715 | Cytoplasmic | A | Cytoplasm | - | - | - | - | - | yes | yes |
| FHUA_ECOLI P06971 |
fhuA | Ferrichrome outer membrane transporter/phage receptor (Ferric hydroxamate receptor) (Ferric hydroxamate uptake) (Ferrichrome-iron receptor) | b0150 JW0146 | OM b-barrel protein (SEC through IM, inserted in OM by BAM), Ferrichrome transporter/phage receptor FhuA | 1by5 PDB ID, chain A, for protein P06971 | Outer Membrane b-barrel protein | H | Cell outer membrane | - | SECB | SEC | SKP, SURA | BAM | yes | yes |
| PROA_ECOLI P07004 |
proA | Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase) (GSA dehydrogenase) | b0243 JW0233 | cytoplasmic peripheral IM protein, Gamma-glutamyl phosphate reductase ProA | TBM Zhang model E12566 (score: 0.99) | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A,F1 | Cytoplasm | - | - | - | - | - | yes | yes |
| USHA_ECOLI P07024 |
ushA | Protein UshA [Includes: UDP-sugar hydrolase (EC 3.6.1.45) (UDP-sugar diphosphatase) (UDP-sugar pyrophosphatase); 5'-nucleotidase (5'-NT) (EC 3.1.3.5)] | b0480 JW0469 | periplasmic protein (SEC through IM), UshA | 1hpu PDB ID, chain A, for protein P07024 | Periplasmic | G | Periplasm | - | - | SEC | - | - | no | yes |
| AROB_ECOLI P07639 |
aroB | 3-dehydroquinate synthase (DHQS) (EC 4.2.3.4) | b3389 JW3352 | cytoplasmic protein, 3-dehydroquinate synthase AroB | TBM Zhang model E11019 (score: 0.881) | Cytoplasmic | A | Cytoplasm | - | - | - | - | - | yes | yes |
| GLGB_ECOLI P07762 |
glgB | 1,4-alpha-glucan branching enzyme GlgB (EC 2.4.1.18) (1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase) (Alpha-(1->4)-glucan branching enzyme) (Glycogen branching enzyme) (BE) | b3432 JW3395 | cytoplasmic protein, 1,4-alpha-glucan branching enzyme GlgB | 4lpc PDB ID, chain B, for protein P07762 | Cytoplasmic | A | - | - | - | - | - | - | yes | yes |
| IDH_ECOLI P08200 |
icd | Isocitrate dehydrogenase [NADP] (IDH) (EC 1.1.1.42) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase) | b1136 JW1122 | cytoplasmic peripheral IM protein, Isocitrate dehydrogenase (NADP) Icd | 1pb1 PDB ID, chain A, for protein P08200 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A,F1 | - | - | TF | - | - | - | yes | yes |
| HEM4_ECOLI P09126 |
hemD | Uroporphyrinogen-III synthase (UROS) (EC 4.2.1.75) (Hydroxymethylbilane hydrolyase [cyclizing]) (Uroporphyrinogen-III cosynthase) | b3804 JW3776 | cytoplasmic protein, Uroporphyrinogen-III synthase HemD | TBM Zhang model E11779 (score: 0.683) | Cytoplasmic | A | - | - | - | - | - | - | yes | yes |
| PFLB_ECOLI P09373 |
pflB | Formate acetyltransferase 1 (EC 2.3.1.54) (Pyruvate formate-lyase 1) | b0903 JW0886 | cytoplasmic peripheral IM protein, Formate acetyltransferase 1 PflB | 1h16 PDB ID, chain A, for protein P09373 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A,F1 | Cytoplasm | - | TF | - | - | - | yes | yes |
| YIDB_ECOLI P09996 |
yidB | Uncharacterized protein YidB | b3698 JW3675 | cytoplasmic protein, YidB | TBM Zhang model E10715 (score: 0.966) | Cytoplasmic | A | - | - | - | - | - | - | yes | yes |
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