E. coli K-12 / MG1655/ ATCC 47076 proteome
| Protein Information | Subcellular Localization | Targeting/Export System | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Protein ID / Accession # (UniProt) |
Gene Name (UniProt) |
Protein Name (UniProt) |
Order Locus Name |
Protein Name (STEPdb) |
Reference structure |
Topology Class Full name (STEPdb) |
Symbol (STEPdb) |
Topology Class UniProt |
Extracellular Appendage | First Level Targeting Chaperoning |
First Level Secretion System |
Second Level Targeting Chaperoning |
Second Level Secretion System |
K-12 Core Proteome (yes/no) |
K-12 Basic Proteome (yes/no) |
| YCIZ_ECOLI A5A614 |
yciZ | UPF0509 protein YciZ | b4596 JW1277 | cytoplasmic protein, UPF0509 YciZ | ab initio Zhang model E10529 (score: 0.672) | Cytoplasmic | A | - | - | - | - | - | - | no | yes |
| YPFM_ECOLI A5A621 |
ypfM | Uncharacterized protein YpfM | b4606 JW2454.1 | cytoplasmic protein, YpfM | TBM Zhang model E14200 (score: 0.571) | Cytoplasmic | A | Cytoplasm | - | - | - | - | - | no | yes |
| 6PGD_ECOLI P00350 |
gnd | 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) | b2029 JW2011 | cytoplasmic peripheral IM protein, 6-phosphogluconate dehydrogenase, decarboxylating Gnd | 3fwn PDB ID, chain A, for protein P00350 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A,F1 | - | - | - | - | - | - | yes | yes |
| FRDA_ECOLI P00363 |
frdA | Fumarate reductase flavoprotein subunit (EC 1.3.5.4) | b4154 JW4115 | cytoplasmic peripheral IM protein, Fumarate reductase flavosubunit FrdA | 5vpn PDB ID, chain E, for protein P00363 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A,F1 | - | - | - | - | - | - | yes | yes |
| DHE4_ECOLI P00370 |
gdhA | NADP-specific glutamate dehydrogenase (NADP-GDH) (EC 1.4.1.4) | b1761 JW1750 | cytoplasmic protein, NADP-specific glutamate dehydrogenase GdhA | 4bht PDB ID, chain A, for protein P00370 | Cytoplasmic | A | - | - | - | - | - | - | yes | yes |
| DHNA_ECOLI P00393 |
ndh | NADH dehydrogenase (EC 1.6.99.3) | b1109 JW1095 | cytoplasmic peripheral IM protein, NADH dehydrogenase Ndh | TBM Zhang model E12316 (score: 0.791) | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A,F1 | Cell membrane | - | - | - | - | - | yes | yes |
| RIR1_ECOLI P00452 |
nrdA | Ribonucleoside-diphosphate reductase 1 subunit alpha (EC 1.17.4.1) (Protein B1) (Ribonucleoside-diphosphate reductase 1 R1 subunit) (Ribonucleotide reductase 1) | b2234 JW2228 | cytoplasmic peripheral IM protein, Ribonucleoside-diphosphate reductase 1 subunit alpha NrdA | 5r1r PDB ID, chain A, for protein P00452 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A,F1 | - | - | TF | - | - | - | yes | yes |
| KHSE_ECOLI P00547 |
thrB | Homoserine kinase (HK) (HSK) (EC 2.7.1.39) | b0003 JW0002 | cytoplasmic protein, Homoserine kinase ThrB | TBM Zhang model E13014 (score: 0.967) | Cytoplasmic | A | Cytoplasm | - | - | - | - | - | yes | yes |
| PTM3C_ECOLI P00550 |
mtlA | PTS system mannitol-specific EIICBA component (EIICBA-Mtl) (EII-Mtl) [Includes: Mannitol permease IIC component (PTS system mannitol-specific EIIC component); Mannitol-specific phosphotransferase enzyme IIB component (EC 2.7.1.197) (PTS system mannitol-specific EIIB component); Mannitol-specific phosphotransferase enzyme IIA component (PTS system mannitol-specific EIIA component)] | b3599 JW3573 | integral IM protein (SEC in IM), PTS system mannitol-specific EIICBA component MtlA | TBM Zhang model E12248 (score: 0.778) | Integral Inner Membrane, cytoplasmic side | B | Cell inner membrane | - | SRP (exp) | SEC | - | - | yes | yes |
| AK1H_ECOLI P00561 |
thrA | Bifunctional aspartokinase/homoserine dehydrogenase 1 (Aspartokinase I/homoserine dehydrogenase I) (AKI-HDI) [Includes: Aspartokinase (EC 2.7.2.4); Homoserine dehydrogenase (EC 1.1.1.3)] | b0002 JW0001 | cytoplasmic peripheral IM protein, Bifunctional aspartokinase/homoserine dehydrogenase 1 ThrA | TBM Zhang model E13013 (score: 0.716) | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A,F1 | - | - | TF | - | - | - | yes | yes |
| RPOD_ECOLI P00579 |
rpoD | RNA polymerase sigma factor RpoD (Sigma-70) | b3067 JW3039 | cytoplasmic nucleoid peripheral IM protein, RNA polymerase sigma factor RpoD | 4lk1 PDB ID, chain F, for protein P00579 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A,N,F1 | Cytoplasm | - | TF | - | - | - | yes | yes |
| AMPC_ECOLI P00811 |
ampC | Beta-lactamase (EC 3.5.2.6) (Cephalosporinase) | b4150 JW4111 | periplasmic protein (SEC through IM), Beta-lactamase AmpC | 2ffy PDB ID, chain A, for protein P00811 | Periplasmic | G | Periplasm | - | - | SEC | - | - | yes | yes |
| DCDA_ECOLI P00861 |
lysA | Diaminopimelate decarboxylase (DAP decarboxylase) (DAPDC) (EC 4.1.1.20) | b2838 JW2806 | cytoplasmic protein, Diaminopimelate decarboxylase LysA | 1knw PDB ID, chain A, for protein P00861 | Cytoplasmic | A | - | - | - | - | - | - | yes | yes |
| CAPP_ECOLI P00864 |
ppc | Phosphoenolpyruvate carboxylase (PEPC) (PEPCase) (EC 4.1.1.31) | b3956 JW3928 | cytoplasmic peripheral IM protein, Phosphoenolpyruvate carboxylase Ppc | 1jqn PDB ID, chain A, for protein P00864 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A,F1 | - | - | - | - | - | - | yes | yes |
| AROF_ECOLI P00888 |
aroF | Phospho-2-dehydro-3-deoxyheptonate aldolase, Tyr-sensitive (EC 2.5.1.54) (3-deoxy-D-arabino-heptulosonate 7-phosphate synthase) (DAHP synthase) (Phospho-2-keto-3-deoxyheptonate aldolase) | b2601 JW2582 | cytoplasmic protein, Phospho-2-dehydro-3-deoxyheptonate aldolase, Tyr-sensitive AroF | TBM Zhang model E11023 (score: 0.941) | Cytoplasmic | A | - | - | - | - | - | - | yes | yes |
| ILVI_ECOLI P00893 |
ilvI | Acetolactate synthase isozyme 3 large subunit (EC 2.2.1.6) (AHAS-III) (ALS-III) (Acetohydroxy-acid synthase III large subunit) | b0077 JW0076 | cytoplasmic protein, Acetolactate synthase isozyme 3 large subunit IlvI | TBM Zhang model E11905 (score: 0.975) | Cytoplasmic | A | - | - | - | - | - | - | yes | yes |
| ILVH_ECOLI P00894 |
ilvH | Acetolactate synthase isozyme 3 small subunit (EC 2.2.1.6) (ALS-III) (Acetohydroxy-acid synthase III small subunit) (AHAS-III) | b0078 JW0077 | cytoplasmic protein, Acetolactate synthase isozyme 3 small subunit IlvH | 2f1f PDB ID, chain A, for protein P00894 | Cytoplasmic | A | - | - | - | - | - | - | no | yes |
| TRPE_ECOLI P00895 |
trpE | Anthranilate synthase component 1 (AS) (ASI) (EC 4.1.3.27) | b1264 JW1256 | cytoplasmic peripheral IM protein, Anthranilate synthase component 1 TrpE | TBM Zhang model E13064 (score: 0.997) | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A,F1 | - | - | - | - | - | - | yes | yes |
| PABA_ECOLI P00903 |
pabA | Aminodeoxychorismate synthase component 2 (ADC synthase) (ADCS) (EC 2.6.1.85) (4-amino-4-deoxychorismate synthase component 2) (Aminodeoxychorismate synthase, glutamine amidotransferase component) | b3360 JW3323 | cytoplasmic protein, Aminodeoxychorismate synthase component 2 PabA | TBM Zhang model E12426 (score: 0.97) | Cytoplasmic | A | - | - | - | - | - | - | yes | yes |
| TRPGD_ECOLI P00904 |
trpGD | Bifunctional protein TrpGD [Includes: Anthranilate synthase component 2 (AS) (ASII) (EC 4.1.3.27) (Anthranilate synthase, glutamine amidotransferase component); Anthranilate phosphoribosyltransferase (EC 2.4.2.18)] | b1263 JW1255 | cytoplasmic peripheral IM protein, Bifunctional TrpG | TBM Zhang model E13063 (score: 0.81) | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A,F1 | - | - | - | - | - | - | yes | yes |
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