E. coli K-12 / MG1655/ ATCC 47076 proteome

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Nucleoid Cytoplasmic Peripheral inner membrane protein facing the cytoplasm Integral inner membrane Ribosomal Inner membrane lipoprotein Peripheral inner membrane protein facing the periplasm Periplasmic Peripheral outer membrane protein facing the periplasm Outer membrane β-barrel protein Peripheral outer membrane protein facing the extra-cellular space Extra-cellular Outer membrane lipoprotein

Protein Information Subcellular Localization Targeting/Export System
Protein ID /
Accession #
(UniProt)
Gene Name
(UniProt)
Protein Name
(UniProt)
Order
Locus Name
Protein Name
(STEPdb)
Reference structure
Topology Class
Full name
(STEPdb)
Symbol
(STEPdb)
Topology Class
UniProt
Extracellular Appendage First Level
Targeting
Chaperoning
First Level
Secretion
System
Second Level
Targeting
Chaperoning
Second Level
Secretion
System
K-12 Core
Proteome
(yes/no)
K-12 Basic
Proteome
(yes/no)
ASPG2_ECOLI
P00805
ansB L-asparaginase 2 (EC 3.5.1.1) (L-asparaginase II) (L-ASNase II) (L-asparagine amidohydrolase II) (Colaspase) b2957 JW2924 periplasmic protein (SEC through IM), L-asparaginase 2 AnsB 5mq5 PDB ID, chain B, for protein P00805 Periplasmic G Periplasm - - SEC - - yes yes
SDHD_ECOLI
P00926
dsdA D-serine dehydratase (EC 4.3.1.18) (D-serine deaminase) (DSD) b2366 JW2363 cytoplasmic protein, D-serine dehydratase DsdA 3ss7 PDB ID, chain X, for protein P00926 Cytoplasmic A - - - - - - no yes
XYLA_ECOLI
P00944
xylA Xylose isomerase (EC 5.3.1.5) (D-xylulose keto-isomerase) b3565 JW3537 cytoplasmic protein, Xylose isomerase XylA TBM Zhang model E13193 (score: 0.976) Cytoplasmic A Cytoplasm - - - - - no yes
ASNA_ECOLI
P00963
asnA Aspartate--ammonia ligase (EC 6.3.1.1) (Asparagine synthetase A) b3744 JW3722 cytoplasmic protein, Aspartate--ammonia ligase AsnA 12as PDB ID, chain A, for protein P00963 Cytoplasmic A Cytoplasm - - - - - yes yes
FLIC_ECOLI
P04949
fliC Flagellin b1923 JW1908 Flagellar extra-cellular peripheral OM protein (Flagellum secreted), Flagellin FliC TBM Zhang model E11528 (score: 0.897) Peripheral outer membrane protein facing the extra-cellular space F4 Secreted Bacterial flagellum flagellum - Flagellum - Fla no yes
RECD_ECOLI
P04993
recD RecBCD enzyme subunit RecD (EC 3.1.11.5) (Exodeoxyribonuclease V 67 kDa polypeptide) (Exodeoxyribonuclease V alpha chain) (Exonuclease V subunit RecD) (ExoV subunit RecD) (Helicase/nuclease RecBCD subunit RecD) b2819 JW2787 nucleoid protein, RecBCD enzyme subunit RecD 5ld2 PDB ID, chain D, for protein P04993 Cytoplasmic, Nucleoid A,N - - - - - - yes yes
FPG_ECOLI
P05523
mutM Formamidopyrimidine-DNA glycosylase (Fapy-DNA glycosylase) (EC 3.2.2.23) (DNA-(apurinic or apyrimidinic site) lyase MutM) (AP lyase MutM) (EC 4.2.99.18) b3635 JW3610 nucleoid protein, Formamidopyrimidine-DNA glycosylase MutM 1k82 PDB ID, chain A, for protein P05523 Cytoplasmic, Nucleoid A,N - - TF - - - yes yes
MCP3_ECOLI
P05704
trg Methyl-accepting chemotaxis protein III (MCP-III) (Ribose and galactose chemoreceptor protein) b1421 JW1417 integral IM protein (SEC in IM), Methyl-accepting chemotaxis III Trg TBM Zhang model E13050 (score: 0.481) Integral Inner Membrane, cytoplasmic side B Cell inner membrane - SRP SEC - - no yes
PTHA_ECOLI
P05706
srlB PTS system glucitol/sorbitol-specific EIIA component (EIIA-Gut) (EIII-Gut) (Glucitol/sorbitol-specific phosphotransferase enzyme IIA component) b2704 JW2673 cytoplasmic peripheral IM protein, PTS system glucitol/sorbitol-specific EIIA component SrlB TBM Zhang model E10387 (score: 0.929) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm A,F1 Cytoplasm - - - - - no yes
SRLD_ECOLI
P05707
srlD Sorbitol-6-phosphate 2-dehydrogenase (EC 1.1.1.140) (Glucitol-6-phosphate dehydrogenase) (Ketosephosphate reductase) b2705 JW2674 cytoplasmic protein, Sorbitol-6-phosphate 2-dehydrogenase SrlD TBM Zhang model E12930 (score: 0.993) Cytoplasmic A - - - - - - no yes
RECN_ECOLI
P05824
recN DNA repair protein RecN (Recombination protein N) b2616 JW5416 nucleoid protein, RecN TBM Zhang model E12676 (score: 0.561) Cytoplasmic, Nucleoid A,N Cytoplasm - - - - - yes yes
AGAL_ECOLI
P06720
melA Alpha-galactosidase (EC 3.2.1.22) (Melibiase) b4119 JW4080 cytoplasmic protein, Alpha-galactosidase MelA TBM Zhang model E12143 (score: 0.942) Cytoplasmic A - - - - - - yes yes
SDIA_ECOLI
P07026
sdiA Regulatory protein SdiA b1916 JW1901 nucleoid protein, Regulatory SdiA 4lfu PDB ID, chain A, for protein P07026 Cytoplasmic, Nucleoid A,N - - - - - - yes yes
CHEA_ECOLI
P07363
cheA Chemotaxis protein CheA (EC 2.7.13.3) b1888 JW1877 cytoplasmic peripheral IM protein, Chemotaxis CheA 2lp4 PDB ID, chain A, for protein P07363 Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm A,F1 Cytoplasm - - - - - no yes
CHPS_ECOLI
P08365
chpS Antitoxin ChpS b4224 JW5750 nucleoid protein, Antitoxin ChpS TBM Zhang model E10034 (score: 0.596) Cytoplasmic, Nucleoid A,N - - - - - - no yes
XYLB_ECOLI
P09099
xylB Xylulose kinase (Xylulokinase) (EC 2.7.1.17) b3564 JW3536 cytoplasmic protein, Xylulose kinase XylB 2itm PDB ID, chain A, for protein P09099 Cytoplasmic A - - - - - - yes yes
NARG_ECOLI
P09152
narG Respiratory nitrate reductase 1 alpha chain (EC 1.7.5.1) (Nitrate reductase A subunit alpha) (Quinol-nitrate oxidoreductase subunit alpha) b1224 JW1215 cytoplasmic peripheral IM protein, Respiratory nitrate reductase 1 alpha chain NarG 1q16 PDB ID, chain A, for protein P09152 Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm A,F1 Cell membrane, Peripheral membrane protein - - - - - yes yes
RND_ECOLI
P09155
rnd Ribonuclease D (RNase D) (EC 3.1.13.5) b1804 JW1793 cytoplasmic protein, Ribonuclease D Rnd 1yt3 PDB ID, chain A, for protein P09155 Cytoplasmic A Cytoplasm - - - - - yes yes
GLPQ_ECOLI
P09394
glpQ Glycerophosphodiester phosphodiesterase, periplasmic (Glycerophosphoryl diester phosphodiesterase, periplasmic) (EC 3.1.4.46) b2239 JW2233 periplasmic protein (SEC through IM), Glycerophosphodiester phosphodiesterase, periplasmic GlpQ 1ydy PDB ID, chain A, for protein P09394 Periplasmic G Periplasm - - SEC - - yes yes
GLPK_ECOLI
P0A6F3
glpK Glycerol kinase (EC 2.7.1.30) (ATP:glycerol 3-phosphotransferase) (Glycerokinase) (GK) b3926 JW3897 cytoplasmic peripheral IM protein, Glycerol kinase GlpK 1bu6 PDB ID, chain Y, for protein P0A6F3 Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm A,F1 - - TF - - - yes yes
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